Farzan Vahedifard

Rush University Medical Center | Rush

At-home neuromodulation with transcranial devices is likely to fill a large gap in the treatment of patients suffering from major depressive disorder (MDD). In fact, many depressed individuals either do not have access to, do not respond to, or simply decline approved pharmacotherapy, evidence-based psychotherapy, and in-office neuromodulation.1–3...

Background: Head injury is a silent epidemic in developed countries and is one of the leading causes of death and disability. Determining the precise and early prognosis of head injury, especially in severe cases, is essential and will help define treatment actions and rehabilitation plans and counsel other family members. The purpose of this study...

Serum creatinine levels also assessed the transplanted kidney's function. Result: Ultrasound showed a significant difference between the two groups in iliac and interlobar PSV. The ROC analysis showed a high diagnostic value of the iliac artery PSV, in distinguishing ATN from kidney transplant rejection. Serum creatinine level correlated directly w...

Introduction: Personal identification is an important aspect of forensic medicine, and different approaches are used. Because of the durant nature of bones, they are regarded as a well-suited part to investigate, especially in complex cases where other body remnants are highly degraded. Many studies have revealed sexual dimorphism and ethnic differ...

Background: Doppler ultrasonography can evaluate vascular and renal parenchymal disorders. In this study, color Doppler patterns in transplanted kidneys were compared with histological diagnosis to develop diagnostic models for transplanted kidney failure. Method: 45 kidney transplant patients participated in this cross-sectional study (16 sufferin...

The considerable connection between OCD and tic disorders, such as Tourette's Disorder (TD), has piqued researchers' curiosity. Tics of TD, are involuntary, stereotyped motor motions or phonic outputs occasionally accompanied by premonitory sensory cravings. Clinically, it is not easy to distinguish between OCD and TD symptoms. Simple motor or phon...

Introduction: The prevalence of substance use disorders is higher in patients receiving opioid analgesics, and pain management in these patients is more challenging. This study aimed to investigate the pattern of analgesic drug administration and evaluate the associated factors. Method: The cross-sectional study was performed on 230 patients admitt...

Introduction: Mood and anxiety disorders are a prevalent and significant leading cause of years lived with a disability worldwide. Existing antidepressants drugs are only partially effective, having burdensome side effects. One-third of patients do not achieve remission after several adequate antidepressant trials, and relapses of depression are fr...

Introduction: Psychosis is the third most debilitating disorder among adolescents worldwide. Very early-onset schizophrenia (VEOS), before age 13, is extremely rare, with a frequency of 1/10,000. Its clinical appearance, course, and outcome are distinct from early-onset (years 13-18) and adult-onset (ages 18 and up) schizophrenia. It is linked to p...

Background: Patients with symptoms without apparent signs suffer from a lack of understanding and support from others, called 'invalidation.' In rheumatoid arthritis (RA), some of the physical problems are often hidden, leading to conflict, and affecting the quality of life (QOL). We investigated the correlation between 'invalidation' of disease fr...

Introduction: Fluoxetine raises the levels of BDNF (brain-derived neurotrophic factor). BDNF is known to improve neurogenesis and plasticity, so it seems to improve Anterior Ischemic Optic Neuropathy (AION). The goal of this study was to find out how Fluoxetine affects the clinical outlook of people with AION. Methods: In this double-blind, placebo...

Delirious mania (D.M.), which is described as an advancement of delirium in a patient with acute mania, is related to the high morbidity and mortality rate. Despite the high occurrence of delirium (15-20%) in bipolar disorder, D.M. is frequently misdiagnosed. D.M. is not classified as a DSM diagnosis, and no treatment guidelines exist. This case re...

Introduction: Fetal Magnetic Resonance Imaging (MRI) provides great anatomic details for diagnosing perinatal disorders when ultrasound is inconclusive. Immediate interventions can be attempted when abnormal anatomic changes of fetal brain structures are identified early during gestation. Measuring Fetal MRI can detect the normal size of brain stru...

Three of every 1000 pregnant mothers have fetuses with neurological abnormalities, so initial detection and categorization of fetal Brain abnormalities are critical. Manually detecting and segmenting Fetal Brain MRI, could be expensive, time-consuming, and have the challenge of interpreter experience. Artificial Intelligence (AI), specifically Mach...

Recent advances in medical image analysis have been made to improve our understanding of how the disease develops, behaves, and responds to treatment. Magnetic resonance imaging (MRI) and positron emission tomography (PET) advanced imaging strategies provide structural and functional phenotypic biomarkers that correlate with key disease processes....

Background: This study aimed to evaluate chronic pain and fatigue in COVID-19 patients after 12 months of hospitalization. Methods: We studied the COVID-19 patients discharged from Hospital, between March 10 to April 20, 2020. Results: A total of 157 patients were included in this study. Forty-three patients (27.4%) complained of chronic fatigue an...

One of the most common causes of chronic abdominal pain is ‘Chronic Abdominal Wall Pain, “CAWP”, which frequently goes undiagnosed. CAWP accounts for 10-30% of patients in surgical, gynecological, and gastrointestinal clinics who have a primary complaint of persistent abdominal pain. CAWP, on the other hand, may be treated quickly and efficiently u...

Sexual dysfunction (SD) is frequently encountered in patients suffering from depression. There is a bidirectional relationship between various types of SD and depression, so the presence or treatment of one condition may exacerbate or improve the other condition. The most frequent sexual problem in untreated depressed patients is declining sexual d...

Neuroplasticity, the brain's capacity to adapt to internal and external environmental changes, occurs physiologically throughout growth and in reaction to damage. Many MRI studies of neuroplasticity have shown strong evidence that the brain changes quickly and extensively when people have new experiences.  In this paper, we review the most advance...

Vascular fenestration is a rare congenital variant, in which a segment of vessels divides into two distinct channels, covered by a layer of endothelium. It is usually asymptomatic, but is sometimes accompanied by other structural abnormalities, such as intracerebral vascular aneurysms. Fenestration may be detected deliberately or accidentally by im...

• This study aimed to evaluate chronic pain and fatigue in patients 12 months after hospitalization for Covid-19. • Methods : We studied the COVID-19 patients discharged from Hospital, March 10 and April 20, 2020. • Results : A total of 157 patients were included in this study. Forty-three patients (27.4%) complained of chronic fatigue and muscle...

Fetal Magnetic Resonance Imaging (MRI) is often considered when ultrasound is inconclusive for assessing fetal anatomy during all phases of gestation. Fetal MRI provides clear images for diagnosis and early detection of perinatal disorders of development • Measuring fetal MRI can be a time-consuming process to attain specificity of brain anatomy me...

Major depressive disorder (MDD) is clinically diverse and has a high frequency in primary care practice. There is no biological diagnostic test for MDD, individuals of various ages and ethnicities are afflicted, and diagnosis is now dependent on the physician's interpretation of the patients' symptoms. Many patients treated in primary care do not r...

Background Gastric cancer is the third leading cause of cancer-related death. Determining molecular and histopathologic tumor features, which may contribute to the development or progression of gastric cancer, can improve the prognosis. Expression patterns of DNA repair proteins such as MLH1, MSH2, MSH6, and PMS2 that are associated with microsatel...

Why Knowing the Mechanism of Radiofrequency is Important? • Patient: Doctor! How do these RF waves help relieve my pain? • Doctor: Well, sometimes it destroys your nerves, and most of the time, it doesn’t! • Patient: So, how does it calm my pain? • Doctor: “What does not kill you, makes you stronger! Understanding the mechanism of radiofrequency...

Besides conventional indications of Radiofrequency Ablation (RFA) in pain management, recently several novel and trending therapeutic targets for RF, have been studied. Different painproducing components can be ablated or modulated by RF to relieve pain. These new indications of RF can be divided into: Headaches, post-operative pains, post-trauma...

Background: Carpal tunnel syndrome (CTS) is the most prevalent entrapment syndrome in the upper limbs, for which pregnancy is a known risk factor. CTS diagnosis is confirmed via nerve conduction studies (NCSs), which sometimes is expensive, and the electrical stimulation makes it an unpleasant diagnostic modality, especially for pregnant subjects....

Background & objective: Transitional cell carcinoma (TCC) is the world's seventh most common tumor and forms more than 90% of urinary bladder tumors. Invasive tumors are associated with poor prognosis, even with surgical treatment and chemotherapy. Some studies have found that an increase in the number of mast cells in TCC is related to the tumor...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the recent outbreak of coronavirus 2019 (COVID-19). Although nearly two decades have passed since the emergence of pandemics such as SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), no effective drug against the CoV family has yet been approved, so there is...

Background: Focal nodular hyperplasia (FNH) is a benign rare liver neoplasm in children and includes only 2% of all pediatric liver tumors. Here we reported the case of a 14-year-old girl with vague flank pain who was managed conservatively. Case presentation: Our case is a 14-year-old child (female), with a 5 cm diameter lesion in the right lob...

Introduction: Optic nerve sheath diameter (ONSD) measured by ultrasound seems to be able to determine increased intracranial pressure. Likewise, US might estimate the severity of acute ischemic stroke at the initial presentation. Prompt diagnosis and optimal treatment in cases of acute ischemic stroke will result in a favorable outcome. Objective...

Ankylosing spondylitis (AS) is a chronic inflammatory disease that causes deterioration in the function of the spine and peripheral joints. In addition to history and examination, imaging is important in diagnosing this disease. Pelvic X-rays in particular may show pseudowidening, erosion, and sclerosis sacroiliac joint. Spinal X-rays may also iden...

Brachymetatarsia is a rare forefoot deformity caused by premature closure of the epiphyseal plate of the metatarsal, which leads to abnormal shortness of a metatarsal bone. Various factors such as trauma, iatrogenic and congenital issues are involved in the formation of this problem with and without association with systematic syndromes (1). This d...