Farinawati Yazid

Farinawati Yazid
Universiti Kebangsaan Malaysia | ukm ·  Faculty of Dentistry

Master of Dental Surgery

About

34
Publications
4,218
Reads
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121
Citations
Citations since 2017
33 Research Items
97 Citations
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Introduction
Farinawati Yazid currently works at the Paediatric Dentistry Unit, Faculty of Dentistry, Universiti Kebangsaan Malaysia. Her research interest is in regenerative dentistry utilizing dental stem cells with various biomaterials and growth factors for in-vitro and in-vivo studies. She is also actively investigating the oral biomarkers both saliva and gingival crevicular fluid in dental diseases detection such as caries, periodontal disease and root resorption.
Additional affiliations
September 2006 - present
Universiti Kebangsaan Malaysia
Position
  • Lecturer

Publications

Publications (34)
Article
Full-text available
Orthodontically induced inflammatory root resorption (OIIRR) is inevitable as the force applied during orthodontic treatment to initiate tooth movement induces inflammation, causing iatrogenic root resorption. Even with the use of new technologies in orthodontic appliances, the traumatic effects on the periodontium are still present. Therefore, a p...
Article
Full-text available
Pembezaan sel stem secara in vitro kepada osteoblas secara umumnya melibatkan gabungan aruhan asid askorbik dan β-gliserofosfat. Namun, β-gliserofosfat didapati menyebabkan penurunan keviabelan sel. Maka, kajian ini adalah untuk menentukan potensi asid askorbik tanpa kehadiran β-gliserofosfat dalam mengaruh pembezaan osteoblas serta mengenal pasti...
Preprint
Background Activity-based costing (ABC) is a micro costing method. The concept of ABC is production of service consumes activities and these activities consume resources. The objective of this study is to conduct an ABC of common treatments for caries management done under general anaesthesia (GA) among paediatric patients at Hospital Canselor Tuan...
Article
Background Proteomic is capable of elucidating complex biological systems through protein expression, function, and interaction under a particular condition. Objective This study was aimed to determine the potential of ascorbic acid alone in inducing differentially expressed osteoblast-related proteins in dental stem cells via liquid chromatograph...
Article
Full-text available
Dental caries is one of the most prevalent chronic diseases. Early detection is prominent to avoid the tooth weakening or worst the tooth loss. UV absorption spectroscopy is a non-invasive techniqueused for the detection of salivary alpha-amylase which are increasing in the presence of caries. Spectrum acquired from patient at Faculty of dentistry,...
Article
Full-text available
This research aimed to investigate the potential of ascorbic acid (Asc) to act independently as an osteogenic induction factor in a murine pre-osteoblast (MC3T3-E1) model. MC3T3-E1 cells were seeded in culture wells and hydroxyapatite scaffold for two-dimensional and three-dimensional analyses respectively. Cell morphology, viability, osteoblast di...
Article
Full-text available
Background: The selection of appropriate scaffold plays an important role in ensuring the success of bone regeneration. The use of scaffolds with different materials and their effect on the osteogenic performance of cells is not well studied and this can affect the selection of suitable scaffolds for transplantation. Hence, this study aimed to inv...
Article
Full-text available
Background A force applied during orthodontic treatment induces inflammation to root area and lead to root resorption known as orthodontically induced inflammatory root resorption (OIIRR). Dentine sialophosphoprotein (DSPP) is one of the most abundant non-collagenous proteins in dentine that was released into gingival crevicular fluid (GCF) during...
Article
Full-text available
Gingivitis and periodontitis are periodontal diseases that present as an inflammatory periodontium. Enterococcus faecalis is a gram-positive, facultative microorganism that can increase periodontal destruction. High levels of medically important pathogens in the periodontitis associated microbiota may pose a risk to the development of infections at...
Article
Aim The aim of this study was to compare dental pulp tissue in human exfoliated deciduous teeth (SHEDs) and dental pulp stem cells (DPSCs) in response to ascorbic acid as the sole osteoblast inducer. Background A cocktail of ascorbic acid, β-glycerophosphate, and dexamethasone has been widely used to induce osteoblast differentiation. However, und...
Article
Full-text available
Aim: The aim of this article is to investigate the association between quality of life (QoL) and oral health problems among residents from low income groups in an urban area. Materials and Methods: Forty-five participants aged between 18 and 70 years residing in a residential area allocated for Malaysian citizens from the bottom 40% household incom...
Article
Full-text available
Glass ionomer cement (GIC) or polyalkenoate cement is a water-based cement that is commonly used in clinical dentistry procedures as a restorative material. It exhibits great properties such as fluoride-ion release, good biocompatibility, ease of use and great osteoconductive properties. However, GIC’s low mechanical properties have become a major...
Preprint
Full-text available
Background: A force applied during orthodontic treatment induces inflammation to root area and lead to root resorption known as Orthodontically Induced Inflammatory Root Resorption (OIIRR). Dentine sialophosphoprotein (DSPP) is one of the most abundant non-collagenous protein in dentine that was released into gingival crevicular fluid (GCF) during...
Article
Caries is one of the non-communicable diseases that has a high prevalence trend. The current methods used to detect caries require sophisticated laboratory equipment, professional inspection, and expensive equipment such as X-ray imaging device. A non-invasive and economical method is required to substitute the conventional methods for the detectio...
Article
Objective The optimal timing of orthodontic tooth movement (OTM) could allow earlier tooth movements across alveolar bone defects while minimizing the adverse effects. The objective of this scoping systematic review was therefore designed to review pre-clinical animal studies on the ideal protocol for the timing of orthodontic traction across alveo...
Article
Full-text available
ABSTRAK Fasa pengekalan adalah asas dalam rawatan ortodontik. Lebih kurang 70% pesakit mengalami kambuh semula selepas rawatan ortodontik. Risiko kambuh semula dapat dikurangkan dengan penggunaan aplians penahan yang sesuai dengan keadaan klinikal pesakit sebelum rawatan dan berdasarkan ciri-ciri aplians penahan. Apabila aplians penahan boleh tangg...
Article
Full-text available
Background Mesenchymal stem cells isolated from the dental pulp of primary and permanent teeth can be differentiated into different cell types including osteoblasts. This study was conducted to compare the morphology and osteogenic potential of stem cells from exfoliated deciduous teeth (SHED) and dental pulp stem cells (DPSC) in granular hydroxyap...
Chapter
This chapter presents an overview related to the modern approach of hydroxyapatite (HA) based composite for biomedical applications. Composite refers to a heterogeneous combination made up of two or more materials having different composition, properties and morphology in order to produce new materials with specific physical, chemical and mechanica...
Article
Full-text available
A hydroxyapatite scaffold is a suitable biomaterial for bone tissue engineering due to its chemical component which mimics native bone. Electronic states which present on the surface of hydroxyapatite have the potential to be used to promote the adsorption or transduction of biomolecules such as protein or DNA. This study aimed to compare the morph...
Article
Full-text available
Tissue engineering aims to restore lost, damaged, diseased or defective tissues in the human body using engineered or regenerated products. The advancement of tissue engineering has given a promising opportunity for better clinical practice in treating dental patients especially in the fields of endodontic, bone and periodontal tissue as well as wh...
Article
Full-text available
Background Orthodontically induced inflammatory root resorption (OIIRR) is unwelcome iatrogenic damage associated with orthodontic treatment. Patients with a high risk of developing OIIRR are commonly monitored using radiographic techniques. Alternative, more sensitive methods using biological markers facilitate the early detection of OIIRR, which...
Article
Full-text available
Studies on porous titanium for use in dental applications have been growing due to their excellent properties such as low elastic modulus, biocompatibility and excellent strength. The porosity and pore size of titanium scaffold play an important role in bone formation. Thus, this paper reviews the properties of titanium scaffold and the relationshi...
Article
Full-text available
The enthusiastic development of non-autogenous bone graft materials to correct oral cleft defects in dentistry is founded on arguments of post-operative morbidity and quantity limitation when using conventional iliac crest bone grafts. While success in tooth movement is usually reported for the grafted extraction socket, the results cannot be extra...
Conference Paper
Full-text available
A force applied during the orthodontic treatment induces inflammation which is essential for tooth movement, can lead to root resorption. Previous research works have proved a protein biomarker which can monitor the root resorption during orthodontic tooth movement. Dentine sialophosphoprotein (DSPP) is one of most abundant non- collagenous protein...
Conference Paper
Full-text available
Human saliva has been studied as a potential diagnostic tool to detect various types of diseases including dental caries. Caries is a multifactorial disease that occurs due to imbalance of host, environmental and microorganism factor. Salivary alpha-amylase direct relationship with caries activity makes it an important biomarker from host-related f...
Article
Full-text available
Abstract. A force applied during the orthodontic treatment induces inflammation which is essential for tooth movement, can lead to root resorption. Previous research works have proved a protein biomarker which can monitor the root resorption during orthodontic tooth movement. Dentine sialophosphoprotein (DSPP) is one of most abundant noncollagenous...
Chapter
Dental caries is one of the serious oral health issues among children in Malaysia especially to those with poor access to healthcare services. According to the national survey, caries prevalence among children in Malaysia are still high at the rate of 74.5%. One of the main preventive strategies that can be applied is through a correct tooth brushi...
Article
Full-text available
Dental pulp stem cells from permanent (DPSC) and deciduous teeth (Stem Cells from Human Exfoliated Deciduous Teeth; SHED) are adult mesenchymal stem cells that are easily available for cellular therapy. Isolation of these cells acquired less invasive approached. The characterization and osteogenic differentiation potential of the DPSC and SHED are...
Article
Full-text available
Abstract: Background and Objective: Effectiveness of bone tissue regeneration utilizing cells and scaffold mainly determined by initial seeding density. Initial seeding density controlled cell-cell interaction which greatly influenced cell osteoblast differentiation. Therefore, the objective of this study was to determine the effect of different in...
Article
Full-text available
This study was conducted to assess the changes of salivary pH level, salivary buffering capacity and salivary flow rate after consumption of tualang honey (TH). Fourty-four USIM dental students who fulfilled the inclusion criteria participated in this experimental blinded crossover study. Criteria for subject selection were: subjects with no active...
Article
Oral Pathology course has always been synonym with practical learning using microscope to identify histological features in order to diagnose. However, many students had expressed their difficulty in learning this subject when using light microscope (LM). The study was to evaluate the effectiveness of digital microscope (DM) as a teaching aid in Or...
Article
Full-text available
The isolation method for dental pulp stem cells (DPSCs) is still unclear to obtain a conducive environment for DPSCs to proliferate. Enzymatic digestion and outgrowth method are two commonly used methods for DPSCs isolation but are not well characterized in mice DPSCs. This study aimed to compare these isolation methods and differentiation potentia...
Chapter
Dental pulp stem cells from permanent (hDPSC) and deciduous teeth (SHED) are adult mesenchymal stem cells that are less invasive and easily available for cellular therapy. The characterization and osteogenic differentiation of hDPSC and SHED are important in manipulating these cells for regenerative medicine and dentistry. Objectives: This study is...
Article
Full-text available
The aim of this study was to investigate the immunodulatory properties of dental pulp stem cells derived from healthy (SCD) and inflamed pulp deciduous (SCDIP) tissues. The overall hypothesis is that SCDIP possess equal immune properties with SCD and could be used as an alternative tissue source in regenerative medicine. An intra-oral examination w...

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Project (1)
Project
Understanding cellular interaction of Dental Stem Cells with different scaffold material for bone tissue engineering. The 3D scaffold material are hydroxyapaptite of different sources (nacre, limestone), polycaprolactone, carbon black, chitosan, hydrogel and titanium. These interactions are observed in in-vitro and in-vivo cell culture.