Faraz Mojab

Shahid Beheshti University of Medical Sciences · Pharmacognosy

Piper nigrum is one of the most familiar spices due to its' pharmacological and physiological properties. Piperine is a main active alkaloid of Piper nigrum with a broad spectrum of biological activities including anti-aging, anti-inflammatory, anti-cancer, anti-depressant, and cognition enhancer, thus it is effective in correlated diseases. Princi...

: Cytotoxic activity of crude extract and fractions (petroleum ether, dichloromethane, and n-butanol) of Artemisia haussknechtii aerial parts was investigated by MTT assay. Dichloromethane fraction showed the highest cytotoxic effect on MCF-7 cell line (IC50 = 297.17 ± 7.99 µg/mL). Phytochemical analysis of the most effective fraction was carried o...

Background: Vulvovaginal candidiasis is the second most common cause of vulvovaginal infections. Due to the increasing resistance to synthetic antifungal drugs, the use of drugs with a natural origin is a priority. The aim of the present study was to compare the effectiveness of Arnebia euchroma with vaginal cream clotrimazole 1% United States Pha...

This research aimed to evaluate the cytotoxicity, anti-bacterial, anti-fungal and heme polymerization inhibition activities, as well as the detection of the chemical composition of essential oils and measurement of the amount of total phenol and flavonoids of Cousinia harazensis and C. calocephala. In-vitro growth inhibitory effects of methanol ext...

Objectives: Heavy Menstrual Bleeding (HMB) is the most important problems of Uterine Leiomyoma (UL). This study aimed to assess the effect of the extract of the Capsella bursa-pastoris (CBP) on the control of HMB and quality of life in patients with uterine leiomyoma. Design: In a double-blind randomized, clinical trial 54 women with uterine leiomy...

Objectives: At the present study, we aimed at evaluating the effect of Salvia officinalis (S. officinalis) extract on "anthropometric indices" and "insulin resistance markers" in Polycystic Ovary Syndrome (PCOS) patients. Design and setting: This was a randomized, triple-blinded, controlled trial performed in gynecology hospitals affiliated to I...

Background: Spermatogenesis is a necessary process in fertility and reproductive capacity of humans. In view of the relative high prevalence of spermatogenesis disorders in men and the failure of treatments provided in conventional medicine, new therapeutic approaches are being considered. This study will be designed to investigate the effect of C...

Introduction: Phlebitis, that disrupts chemotherapy, is the inflammation of the vein and the most common complication of intravenous injection of chemotherapy drugs. Aim: the aim was determine the effect of topical application of N. sativa oil on the prevention of phlebitis caused by chemotherapy. Methods: This single-blind clinical trial was condu...

Antidepressant-like activity of T. kotschyanus has been recently reported by scientists but insufficient attention has been so far devoted to T. kotschyanus, and there is a lack of information on the other neurobehavioral effects and side effects of this species. In the current study, the anticonvulsant, anxiolytic, and sedative-hypnotic, effects o...

Background & Aims: Candidiasis accounts for 50-90% of vaginal infections in women. Resistance to azole drugs has prompted research into new drugs for the treatment of vaginal infections. The present study aimed to compare the effects of Glycyrrhiza Glabra vaginal cream and clotrimazole on the symptoms of fungal vulvovaginitis. Materials & Methods:...

Background and purpose Chemotherapy-induced phlebitis (CIP) is one of the most important and common complications in patients with cancer. Currently, the use of complementary methods to prevent or alleviate phlebitis symptoms has attracted great attention. In this study, we aimed to assess the effects of topical sesame oil in reducing the pain seve...

Background: Ferula species have shown wide range of pharmacological properties but there is no study on oral safety profile of Ferula persica due to standard toxicology guidelines. Objective: This study aimed to evaluate the acute and subchronic oral toxicity of the alcoholic extract of the aerial parts of Ferula persica to provide its safe dose fo...

Episiotomy is one of the most common midwifery interventions method for preventing injuries to the pelvic floor during the delivery process. Traditional medicine has a special place in improving the quality of postpartum care. Sesame is one of the herbs with anti-inflammatory, anti-bacterial and antioxidant activity. This study was evaluate the eff...

We conducted a double-blind randomized placebo controlled trial to evaluate the impact of Lemon balm (Melissa officinalis L.) on the bleeding and systemic manifestations of menstruation. A total of 90 students were randomly assigned to treatment or placebo group. Bleeding and systemic manifestations were evaluated with a menstrual pictogram and mul...

Background The present study was conducted on the effect of prangos ferulacea vaginal cream on accelerating the recovery of bacterial vaginosis. Methods This randomized controlled clinical trial was conducted on 100 non-pregnant women referring to health centers affiliated to Lorestan University of Medical Sciences in 2016 with the diagnosis of ba...

Objectives: Heavy menstrual bleeding (HMB) is one of the leading causes of low quality of life and iron deficiency anemia in women. This study aimed to determine the effect of hydroalcoholic extracts of Capsella bursa-pastoris on HMB. Design: This study is a triple-blinded, randomized clinical trial. Setting: The study was conducted in gynecol...

Using plants and natural products as medicine is increasing every day. The reason might be a tendency that the societies mostly have toward natural and original products especially natural drugs. Essential oils are referred to aromatic composition found in different parts of a plant and can be used for different remedial and hygienic purposes. One...

Bacterial vaginosis (BV) is a common disorder among women of reproductive age. This study aimed to compare the effect of a Calendula officinalis extract-based cream and metronidazole on BV among women of reproductive age. In this study, 80 women of reproductive age with BV were randomly assigned to the C. officinalis (n = 40) or metronidazole (n =...

The essential oils are frequently used in food processing industry, perfumery, cosmetics, and pharmaceuticals. Most of the oils were obtained by steam distillation and water distillation. It is necessary to specify the best conditions of essential oils production to get much more major compound(s) and higher yield oil. So, fennel oil was selected i...

Because of undesirable side effects of synthetic antioxidants and antibiotics, there is considerable interest in the use of phytomedicines. For this purpose, the present study evaluated total phenolic content, antibacterial, and antioxidant effect of ethanolic extract of Helichrysum leucocephalum for the first time in the world. Ethanolic extract o...

Primary dysmenorrhea refers to painful cramps during menstruation with no organic reason. With respect to its high incidence and adverse outcomes in quality of life and some evidences regarding the sedative and antispasmodic effects of Melissa officinailson smooth muscles as an herb, this double-blind clinical trial was conducted to determine the e...

Introduction: Premenstrual syndrome (PMS) is one of the most common psychosomatic disorders in women which significantly affects their social quality of life. Some studies have demonstrated the effects of Salvia on some problems of menstruation. Therefore, this study was performed with aim to investigate the effects of Salvia extract on the symptom...

Introduction: Nowadays, herbal essence and aromatherapy are used as a form of complementary medicine and nonpharmacological interventions alongside modern medicine and pharmacological interventions. Aim: To evaluate the effect of chamomile flower essence on pain severity following elective caesarean section under spinal anaesthesia. Materials and M...

Objective Painful nipple fissure is a troublesome problem for breastfeeding mothers. This study was conducted to evaluate the effect of saqez (Pistacia atlantica) ointment on the improvement of nipple fissure in breastfeeding women during one-month follow-up. Materials and Methods This randomized controlled clinical trial was conducted on 100 elig...

Background Nipple fissure is a common problem in breastfeeding women, and the main reason for the early discontinuation of breastfeeding. Objective To determine the effect of Saqez (Pistacia atlantica) ointment on the treatment of nipple fissure and nipple pain in breastfeeding women. Methods This randomized clinical trial was conducted on 100 su...

The species Asteraceae Centaurea repens (Asteraceae), known as Acroptilon repens, and Talkhe in persian is used in folk medicine as an emetic, anti-epileptic, and anti-malaria herb in many parts of the world but its toxic effects have not determined yet. This study aimed to evaluate the acute and subchronic toxicity of this extract to find its poss...

Objectives: Postpartum hemorrhage (PPH) is one of three main causes of maternal mortality and a life-threatening condition throughout the world. PPH can have irreversible complications for the mother even if it does not lead to death. This study was conducted to determine the effect of hydroalcoholic extract of Capsella bursa pastoris on early PPH...

Introduction: Postpartum after pain relief is effective in convenience of the mother and improve her interaction with the newborn.one of the ways of pain relief is using herbal medicines. Aim: This study was conducted to compare the effect of mefenamic acid (the common pain reliever) and anise capsule on postpartum after-pain. Method: In this cli...

The essential oil composition of flowering aerial parts of Centaurea imperialis Hausskn. ex Bornm. (Asteraceae) from Iran was analyzed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) for the first time. Thirty seven constituents constituting 88.6% of the total oil were detected. The sesquiterpene hydrocarbons had the hig...

Introduction: Dysmenorrhea is one of the most common gynecological problems in women which can be treated with chemical drugs, herbal medicines, acupuncture, acupressure, and massage therapy. With regard to the possible positive effect of Achillea-Millefolium (AM) on dysmenorrhea and lack of adequate studies in the area, this study was performed wi...

Because of inappropriate use of antibiotics and prevalence of resistant bacteria, there is urgent need for antibacterial drugs that have fewer side effects than antibiotics. Myrtus communis is a medicinal plant which had many uses in traditional medicine. In this study, ethanol leave extract of this plant is tested on Acinetobacter baumannii. In t...

Objectives: To investigate the effects of Matricaria recutita and Mentha piperita on oral mucositis (OM) in patients undergoing hematopoietic stem cell transplantation (HSCT). Design: Randomized double blind placebo controlled clinical trial. Setting: Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, and Bone Marrow Transpla...

Primary dysmenorrhea is a prevalent issue and it can reduce the quality of life in many females worldwide. Based on the properties of Teucrium polium as a herbal medicine with analgesic and inflammatory properties, this triple-blind, randomized, placebo controlled trial was performed. The study aimed to evaluate the effects of Teucrium polium on th...

Background and objectives Primary dysmenorrhea refers to painful menstrual cramps without an organic cause and is one of the most common problems for women during reproductive ages. Given the high prevalence of primary dysmenorrhea and its undesirable effects on the quality of life, and also given the evidence on the analgesic properties of pepperm...

Introduction: Nowadays, use of non-pharmacological methods and complementary medicine to reduce pain intensity and anxiety during labor is increasing. Therefore, this study was performed with aim to compare the effects of Peppermint and Clove essential oil aroma on pain intensity and anxiety at first stage of labor. Methods: This clinical trial stu...

Primary dysmenorrhea is a prevalent problem and its effects decrease the quality of life in many women across the world. Due to the side-effects of synthetic drugs, there is an increasing trend toward herbal medicine. The aim of this study was to research the effect of Teucrium Polium compared to placebo on the pain duration of Dysmenorrhea. This t...

The Publisher regrets that this article is an accidental duplication of an article that has already been published, http://dx.doi.org/10.1016/j.ctcp.2015.09.003. The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.

BACKGROUND AND OBJECTIVE: Similar to other wounds, episiotomy could lead to infections and delayed recovery. Since olive oil has antibacterial and wound healing properties, this study aimed to compare the effects of cold compress with gel packs and topical olive oil on the recovery of episiotomy wounds in primigravid women. METHODS: This clinical...

Background and Objectives: Considering the painfulness of labor and its resulting anxiety, and also, complications such as uterine dysfunction, prolonged labor, and unpleasant memories, the present study was performed aimed to investigate the effect of peppermint aroma on the level of pain and anxiety in the first stage of labor in nulliparous wome...

Background: Rhus coriaria was growth in some areas of Iran. Fruit powder is used as a flavor in foods. Fruits are used as traditional drug, too. Some researches have isolated some phytochemicals from thye herb. There isn't any report about identification of the essential oil of this plant. Objectives: Identification of the essential oil of seeds an...

Background: Primary dysmenorrhea, sometimes with one or more systemic symptoms and is associated with severe bleeding. Objective we conducted a double-blind randomized placebo controlled clinical trial to evaluate the impact of Valerian on the bleeding and systemic manifestations of menstruation. Methods: A total of 100 students were randomly assig...

Itching is one of the most common skin symptoms. Generalized pruritus occurs in 1-8% of pregnant women. It can create unpleasant feeling for these women especially at nights. Most pregnant women avoid using synthetic drugs because of their side effects. Peppermint is a plant which has been used as a traditional drug in Iran. It decreases skin’s tem...

To evaluate the impact of valerian-a herb with sedative effects and antispasmodic effects on smooth muscles-on the severity of dysmenorrhea. In a double-blind, randomized, placebo-controlled trial, 100 students were randomly assigned to receive valerian (n=49) or placebo (n=51). Valerian (dose 255 mg) was given 3 times daily for 3 days beginning at...

Peristomal skin complications interfere with stoma appliance use and negatively affect patient quality of life. To find an alternative to long-term peristomal skin treatment involving corticosteroid products, a prospective study was conducted to compare the effect of a German chamomile solution to topical steroids on peristomal skin lesions in col...

Background: Menstrual bleeding is a reaction of periodic falling secretary endometrial for the reason that decreases production of estradiol and progesterone. In traditional medicine, Foeniculum vulgare Mill is used as a tonic, sedative, galactogogue drug and increases menstrual bleeding. Objective: This study aimed to determine efficacy of Foenicu...

During the last two decades, various medicinal plants have been studied for their possible antimicrobial activity to discover new antimicrobial agents capable of resolving problems such as the development of drug resistance in pathogenic microorganisms as well as the side effects of some present antibiotics. In this study, the antibacterial activit...

The roots and rhizomes of Tanacetum parthenium (L.) Schulz. Bip. (Asteraceae), have been used in Iranian traditional medicine under the name of Aqhovan, as digestive and stomachic tonic. Composition of the essential oil, which was obtained from the root of T. parthenium collected from Karaj, was determined by gas chromatography, combined GC/MS and...

Background: One of the famous medicinal plants is Cucurbita pepo (Cucurbitaceae), which its seeds used as diuretic and anthelminthic. Recently, the seeds have used as symptomatic relief of Benign Prostate Hyperplasia. It is said, seeds' steroids are responsible for these effects. Objectives: This research was performed for identification and quanti...

Introduction: The Persian toothbrush tree or Miswak (Salvadora Persica L.) has been used as a brushing stick for more than 1,300 years. Pharmacological studies indicated antibacterial and antiinflammatory activities of Miswak extract. The present study was performed to determine antibacterial effects of Miswak extract.Material and Methods: The pres...

Effects of different carbon sources on growth and production of antifungal agent(s) by Gymnopilus spectabilis were investigated. Different carbon sources including; Glucose, fructose, lactose, maltose, manitol and sucrose at the concentration of 10 g/l and slow releasing carbon sources including malt extract and soluble starch at the concentration...

The essential oil of Stachys lavandulifolia Vahl (Lamiaceae) was isolated by of the aerial parts of the plant, with a yield of 0.25%. The chemical composition of volatile oil was analyzed by capillary GC and GC/ MS. The main components were germacrene-D (13.2%), β-phellandrene (12.7%), β-pinene (10.2%), myrcene (9.4%), α-pinene (8.4%) and Z-β-ocime...

A phytochemical screening of fifty five Iranian plants belonging to 21 families was carried out. A qualitative phytochemical analysis was performed for the presence of alkaloids, tannins, saponins and flavonoids. The medicinal uses of these plants are also reported

The essential oil of the root of Heracleum persicum (Apiaceae) was analyzed by capillary GC and GC /MS. The major constituents were identified as viridiflorol (23.05 %), elemol (3.63 %), β-maliene (3.07 %), spathulenol (3.34 %) and 2-tetradecanol (3.38 %).