Fahmi KhanHamad Medical Corporation | HMC · Department of Medicine (Hamad General Hospital)
Fahmi Khan
MB BS, CABMs
About
128
Publications
590,599
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Introduction
Name: Fahmi Yousef Ahmed Khan
Date of Birth: 06/11/1964
Place of Birth: Aden/Republic of Yemen
Marital status: Married/three children
Nationality: Yemeni
Additional affiliations
January 2007 - present
September 2000 - October 2001
University of sciences and technology/Sana'a-Yemen
Position
- Research Assistant
Description
- I worked as assistance professor in medicine at university of sciences and technology/Sana'a-Yemen, which is a private university.
Education
September 1995
Al Thawra Modern General Hospital, Sana’a/Yemen
Field of study
- Arab Board Certificate in Internal Medicine
September 1985 - September 1992
Faculty of medicine, Aden University, Yemen
Field of study
Publications
Publications (128)
Background: Urogenital tuberculosis (UGTB) has not been extensively studied in the Gulf region, particularly in Qatar. This study aimed to describe the incidence, demography, presentation, diagnosis, and treatment outcomes of UGTB among adult patients in Qatar.
Materials and Methods: This retrospective descriptive study was conducted from January 1...
Tumor lysis syndrome (TLS) represents a serious oncological emergency characterized by hyperu-ricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia, carrying the potential for life-threatening complications such as arrhythmias, renal failure, and seizures. The diagnostic process relies on serum markers, though limitations in radiological and e...
Corynebacterium spp. are Gram-positive bacteria, and recent studies have proposed a potential link between granulomatous mastitis and Corynebacterium kroppenstedtii infections, posing a challenge in selecting appropriate antibiotics, particularly in pregnant women. A young pregnant woman presented with a palpable lump in her left breast. Subsequent...
Background: There is a lack of reliable information on stroke risk factors, clinical presentation, and mortality. The aim of this study was to describe stroke risk factors, clinical presentations, and in-hospital mortality and to identify the independent predictors of mortality among stroke patients admitted to three hospitals in Shabwa Governorate...
Background
Diabetes mellitus and central obesity are more common among South Asian populations than among White British people. This study explores the differences in diabetes and obesity in South Asians with stroke living in the United Kingdom, India, and Qatar compared with White British stroke patients.
Methods
The study included the UK, Indian...
Background: The incidence of stroke in the Middle East is high, given its relatively young population. Smoking is a well-recognized risk factor for ischaemic stroke, and its high regional prevalence may partly account for this increased stroke risk. This research aims to determine whether young male South Asian migrants in Qatar were adversely affe...
We described a rare case of a splenic infarction associated with typhoid fever in a 26-year-old Bangladeshi man who returned from a vacation 10 days ago from his home country and presented to the emergency department with fever followed by left hypochondrial pain. Contrast-enhanced computed tomography of the abdomen showed multiple areas of splenic...
Background: There is a lack of adequate data about the prevalence and types of tuberculosis (TB) disease in Hadramout Al-Sahel, Yemen. Hence, this study aimed to investigate the prevalence, types, and outcomes of TB disease in Hadramout Al-Sahel, Yemen. Materials and Methods: This cross-sectional study was conducted at the National TB Program (NTP)...
Background
The daily morning round is a routine activity performed by medical teams. During the morning round, updates on the patient’s clinical condition, new laboratory results, and other test results are reviewed and discussed between team members, the patient, and at times the family. Completing these tasks takes time. The design of the patient...
Background: Intracerebral hemorrhage (ICH) has not been widely investigated in young adults. This study aims to describe the risk factors of ICH with a focus on the possible effect of non-modifiable risk factors, such as genetic factors, to assess the ICH outcomes, and to identify the prognostic factors after ICH among young adult patients. Methods...
We described the case of a 34-year-old Bangladeshi man with an unremarkable personal and family history who presented to the emergency department with severe upper abdominal pain of one day’s duration and with elevated serum amylase and lipase. Further work-up revealed a serum triglyceride level of 39.8 mmol/L and his thyroid function test was cons...
Immune thrombocytopenia associated with tuberculosis is a rare clinical entity. We report immune thrombocytopenia associated with pleural tuberculosis in a 22-year-old Ethiopian previously healthy man who presented to the emergency department with one-month history of fever, night sweats and productive cough. Chest x-ray showed right pleural effusi...
1) Background: Qatar does not have any indigenous cases of dengue; however, the influx of immigrants from dengue endemic countries, the environment, and climate suitability for Aedes vector mosquitoes suggest a potential risk for local transmission. In this study, we investigated various demographic factors to determine the epidemiological features...
Background
The incidence of ESBL infections is exponentially increasing with variable prevalence among geographical areas and treatment settings. Identifying local prevalence rate and patient-related factors will help in earlier recognition and initiation of appropriate antibiotics treatment of patients with ESBL infections.
Methods
Retrospective...
A novel rapid spreading and changing virus called SARS-CoV-2 appeared in Wuhan city in December 2019. It was announced by the World Health Organization (WHO) as a pandemic disease in March 2020. It commonly presents with respiratory symptoms; however, it may be asymptomatic. Electrolyte abnormalities are not uncommon features of SARS-CoV-2 infectio...
Chronic kidney disease (CKD) is one of the most common disabling diseases globally. The main etiopathology of CKD is attributed to progressive renal fibrosis secondary to recurrent renal insults. Anemia is a known complication in CKD patients, associated with higher hospitalization rates and increased mortality risk. CKD-associated anemia (CKD-AA)...
The past decades have witnessed several attempts to establish renowned medical journals in the Republic of Yemen. Some of these initiatives were successful but fell short of the researchers' expectations because they failed to meet international standards of scholarly writing in the medical field. Recently, the civil war has dashed any hope of laun...
Hypertension (HTN) is common in chronic kidney disease (CKD), and it may aggravate CKD progression. The optimal blood pressure (BP) value in CKD patients is not established yet, although systolic BP ≤130 mmHg is acceptable as a target. Continuous BP monitoring is essential to detect the different variants of high BP and monitor the treatment respon...
Background & objectives:
Splenic abscess (SA) is a rare clinical entity. There is a lack of information on SA in most Arab and Gulf countries, including Qatar. This study describes the demographics, clinical features, microbiologic etiologies, treatments, and outcomes of patients with SA at the largest tertiary medical center in Qatar over the pre...
Background: There is a lack of robust epidemiological information on portal vein thrombosis (PVT) in Qatar. This study aimed to describe the risk factors, clinical presentation, diagnosis, and treatment outcomes of PVT in patients with and without liver cirrhosis admitted to Hamad General Hospital.
Recent studies have shown that genetic factors may play an important role in the pathogenesis of stroke, as known modifiable and non-modifiable risk factors may account for only 50% of the risk of stroke. Evidence for a genetic basis can be elucidated from twin studies, family history studies, and animal models. Qatar is currently leading the strok...
Background: Data on the effect of metformin on serum vitamin B12 (VitB12) level in patients with type 2 diabetes mellitus (T2DM) in Qatar are limited; therefore, we aimed to assess the prevalence of VitB12 deficiency and its related factors among patients with T2DM treated with metformin at Hamad General Hospital in Doha, Qatar, from January 1, 201...
Background: Statins are well tolerated but associated with various statin‑associated symptoms, including statin‑associated rhabdomyolysis.
Objectives: The aim of this study was to evaluate the frequency of rhabdomyolysis in patients treated with various statins and to describe their
clinical features and outcomes in our local setting. Patients and...
Serum calcium concentration is the main determinant of parathyroid hormone (PTH) release. Defect in the activation of vitamin D in the kidneys due to chronic kidney disease (CKD) leads to hypocalcemia and hyperphosphatemia, resulting in a compensatory increase in parathyroid gland cellularity and parathyroid hormone production and causing secondary...
Chronic Kidney Disease (CKD) and end-stage renal disease (ESRD) are associated with significant heart structure and function changes such as increased left ventricular muscle mass, arrhythmias, and sudden death. This interplay of pathophysiological phenomena secondary to either acute or chronic kidney disease leading to Chronic heart dysfunction is...
BACKGROUND: Reports on coronavirus disease 2019 (COVID-19) associated with acute pancreatitis continue to emerge. In this series, we present three cases of acute pancreatitis associated with COVID-19 with no obvious etiology.
CASE REPORTS: The first case was a 47-year-old man who presented with severe abdominal periumbilical pain, preceded by fever...
We reported an anaphylactic reaction following ingestion of rivaroxaban in a 48-years-old male, who was recently discharged from the hospital as a case of deep vein thrombosis. At home, the patient developed a diffuse itchy skin rash, shortness of breath, and vomiting 30 minutes after rivaroxaban ingestion. Emergency Medical Service found that the...
Background:
several studies have been reported piperacillin-tazobactam (TAZ / PIPC)-associated AKI with various frequencies. The aim of this study was to determine the frequency of TAZ/PIPC- associated AKI among our patients and to identify the risk factors for this clinical entity.
Methods:
this retrospective cross-sectional study was conducted...
COVID-19 has surfaced as a multi-organ disease predominantly affecting the respiratory system. Detection of the viral RNA through reverse transcriptase–PCR (RT-PCR) from a nasopharyngeal or throat sample is the preferred method of diagnosis. Recent evidence has suggested that COVID-19 patients can shed the SARS-CoV-2 for several weeks. Herein, we r...
Background & objectives:
Enterococcal meningitis/ventriculitis (EMV) is a relatively rare condition that usually affects patients with underlying diseases. This study was designed to describe the clinical profile, laboratory parameters, treatment, and outcomes of EMV in patients admitted to Hamad General Hospital, Qatar.
Methods and material:
Th...
Prolonged SARS-CoV-2 Shedding in Six COVID-19 Patients more than 6 weeks: Case Series and Literature Review
The concomitant occurrence of tuberculous adenitis and Hodgkin lymphoma is rare, posing a diagnostic dilemma since both have similar symptoms, such as lymphadenopathy, weight loss, fever, and night sweats. We reported such a case in a 15-year-old girl who presented with fever and neck swelling and was found to have lymphadenopathy. A biopsy of the...
Objectives: We sought to evaluate the role of bronchoscopy-related procedures such
as bronchoalveolar lavage (BAL), bronchial wash (BW), bronchial brush (B brush),
transbronchial biopsy (TBB), and post-bronchoscopy sputum (PBS), alone or in
combination, in the rapid diagnosis of negative sputum smear disseminated tuberculosis
(TB). Methods: We perf...
Background:
The main purpose of this study was to describe the demographic and clinical features of cryptic disseminated TB; it was also aimed to shed light on diagnostic test, procedure results, organ involvement, and outcomes of cryptic disseminated TB in patients with confirmed disseminated TB.
Materials and methods:
We performed a secondary...
Background:
Qatar is located on the north-eastern coast of the Arabian Peninsula. Qatari natives account for less than 15% of the population while the largest migrant group comprising 60% derives from South Asia. Despite projections that stroke burden in Qatar will increase with population ageing, epidemiological studies focusing on stroke in Qata...
Malaria remains a significant public health challenge and is of global importance. Imported malaria is a growing problem in non-endemic areas throughout the world and also in Qatar due to a massive influx of migrants from endemic countries. Antimalarial drug resistance is an important deterrent in our fight against malaria today. Molecular markers...
Introduction: Typhoid splenic abscess is a rare clinical entity that can be fatal if left untreated. Herein, we reported a case of typhoid splenic abscess who responded to ultrasound-guided aspiration and antibiotic therapy. Case Presentation: A 25-year-old Nepalese man with no significant medical history presented to the emergency department with...
Objectives: We sought to describe the epidemiological and clinical features of typhoid
fever in Qatar. Methods: We conducted a retrospective study of adult patients treated
for typhoid fever at Hamad General Hospital and Alkhor Hospital between 2005 and
2012. Results: The mean age of the 354 patients enrolled in the study was 28.4±9.3
years; 296 (8...
Background/aims:
Acute pancreatitis (AP) is one of the most common gastrointestinal causes of hospital admission in Qatar. The aim of the present study was to investigate the epidemiological features and demographic characteristics of patients with AP and to estimate the annual incidence rates of this disease among adult inhabitants in Qatar.
Mat...
We report a case of Haemophilus parainfluenzae pyogenic liver abscess in a 53-year-old Filipino female who was admitted with a 3-day history of abdominal pain and fever. Clinical examination showed tenderness in right hypochondrium, and the liver edge was just palpable. Abdominal ultrasound revealed heterogeneous lesion in the left liver lobe, cons...
Background and Objective: Cerebral venous sinus thrombosis (CVST) is associated with serious morbidity and mortality. This study aimed to analyze the characteristics of patients with CVST, clinical features, and predisposing factors of CVST in a series of 43 patients. Subjects and Methods: We conducted a retrospective study including 43 patients wi...
Imported malaria has been a great challenge for public health in Qatar due to influx of
large number of migrant workers. Antimalarial drug resistance has emerged as one of the
greatest challenges facing malaria control today. Monitoring parasite haplotypes that
predict susceptibility to major antimalarial can guide treatment policies. This study ai...
Plasmodium vivax is the most prevalent parasite worldwide, escalating by spread of drug resistance. Currently, in Qatar, chloroquine (CQ) plus primaquine are recommended for the treatment of P. vivax malaria. The present study examined the prevalence of mutations in dihydrofolate reductase (dhfr), dihydropteroate synthase (dhps) genes and CQ resist...
Helicobacter pylori is a ubiquitous organism that is present in about 50% of the global population. Chronic infection with H. pylori causes atrophic and even metaplastic changes in the stomach, and it represents a key factor in the etiology of various gastrointestinal diseases, ranging from chronic active gastritis without clinical symptoms to pept...
Background and Objectives
Bacterial meningitis is a common medical condition in Qatar. The aim of this study was to describe the clinical characteristics of bacterial meningitis, the frequency of each pathogen, and its sensitivity to antibiotics and risk factors for death.
Patients and Methods
This retrospective study was conducted at Hamad Genera...
Editorial Serum procalcitonin (PCT), which is usually produced in thyroid C-cells, is a precursor of calcitonin. In general, PCT is not released into the blood and, therefore, cannot be detected in healthy individuals [1]. However, serum procalcitonin increased significantly in response to stimulation by bacterial infections showing a favorable pha...
We report a case of group B streptococcus meningitis in a 72-year-old female patient who was admitted in our hospital with a 21-day history of bilateral lower thigh pain and swelling associated with fever, headache, and vomiting. Her past medical history was remarkable for DM type 2, hypertension, and hypothyroidism. Upon admission, examination sho...
Background: There is limited information about extra pulmonary tuberculosis (EPTB) in Qatar. The aim of this study is to describe the demographic characteristics of patients with Tuberculosis (TB) in Qatar, and to compare the characteristics of EPTB with those of Pulmonary Tuberculosis (PTB). Patients and Methods: The study was conducted at Hamad M...
Objective
. The purpose of this study is to collect data on epidemiology, microbiology, and outcome of VAP in our ICUs for reevaluation of the therapeutic strategies.
Methods
. This retrospective study involved all adult patients, 15 years of age or older, diagnosed with VAP in multidisciplinary ICUs at Hamad General Hospital between January 2010 a...
This retrospective study was conducted at Hamad General Hospital, Qatar, to describe the demographic data, clinical features underlying diseases, antimicrobial susceptibility, and outcome of A. baumannii infection. It involved all adult patients 15 years of age or older who were managed at Hamad General Hospital for A. baumannii infection from Janu...
Objectives: To describe the demographic, clinical features, diagnostic and procedure results, organ involvement and outcomes in patients with disseminated tuberculosis (TB).
Patients and methods: This retrospective observational study was conducted at Hamad general hospital in Qatar. It involved all patients 15 years of age or older who were admitt...
Background
Imported malaria has been a great challenge for public health in the State of Qatar due to the large number of immigrant workers come from the Indian subcontinent and Sub-Saharan Africa. Antimalarial drug resistance has emerged as one of the greatest challenges facing malaria control today. Chloroquine (CQ) resistance in Plasmodium falci...
Rhabdomyolysis syndrome has many acquired
pathophysiological causes, resulting in a common
pathway of muscle tissue degradation and
the dispersing of its components onto circulation,
causing systemic effects such as electrolyte
abnormalities, arrhythmia, kidney injury,
compartment syndrome, and DIC. Exertional
rhabdomyolysis (ER) is the most common...
Aim:
The aim is to determine the pattern of patients with colorectal cancer (CRC) seen in two tertiary hospitals in Benghazi, Libya.
Materials and methods:
The cohort includes all patients of CRC who were presented between January 2007 and December 2009 to the Oncology Department, Aljomhoria Hospital and 7th October Hospital, Benghazi. Patient's a...
Clostridium difficile is a Gram-positive, strictly anaerobic, spore-forming bacterium. It is the most common cause of antibiotic-associated diarrhea in hospitals and other healthcare facilities and is of significant concern because of the increasing morbidity and mortality rates as well as increased health care costs. Spectrum of presentation of Cl...
Objective:
To describe the clinical presentation, underlying diseases, antimicrobial susceptibility, treatment and outcome of Klebsiella pneumoniae meningitis patients.
Methods:
This retrospective study involved all patients with 15 years of age or older who admitted to Hamad General Hospital with culture proven Klebsiella pneumoniae meningitis...
Objective:
To describe the etiology, clinical presentation, management and outcome of liver abscess in adult patients admitted at Hamad general hospital, Qatar.
Methods:
A cross sectional study was conducted to involve all adult patients who sequentially encountered episodes of liver abscess during the period from January 1, 2009, to December 31...
We report a case of ischaemic hepatitis associated with recurrent fast atrial fibrillation (AF) episodes in a 59-year-old male who presented with shortness of breath, nausea and vomiting. The patient had a history of ischaemic cardiomyopathy. An emergency electrocardiogram showed fast AF with a ventricular rate of 190 min−1. The aspartate aminotran...
Rhabdomyolysis, literally meaning the breakdown of muscle tissue, is a common syndrome with many causes, acquired ones such as exertion, trauma, infections, temperature extremes, drugs, toxins, electrolyte and endocrine abnormalities, and congenital ones such as myopathies and connective tissue disorders. All results in a common pathophysiologic pa...
We report four cases of nosocomial E. coli meningitis, in male patients with accidental and neurosurgical trauma. The interval between accidents/neurosurgical procedures and the onset of meningitis was 2-15 days (mean 6.25 days). The most consistent clinical features were fever and deterioration of consciousness level. Emergence of extended spectru...
We report isoniazid (INH)-induced encephalopathy in two male patients on hemodialysis. One of them had tuberculous adenitis, and the other had pulmonary tuberculosis. Both were given rifampicin, INH, pyrazinamide, and ethambutol with pyridoxine 40 mg/day. Two patients developed disturbances in consciousness. After excluding other causes, INH-induce...
The aim of this retrospective study was to determine the epidemiological and clinical characteristics, coexisting conditions, causative organisms, and outcomes of all adult patients 15 years of age or older who had definite septic arthritis at Hamad General Hospital, Qatar, from 2006 to 2011. During this period, 56 patients were diagnosed with sept...
To investigate the diagnostic utility of interferon-gamma (IFN-γ) and adenosine deaminase (ADA) in tuberculous pleural effusions by determining the best cutoff levels of these two markers for pleural tuberculosis, in the context of the local epidemiological settings in Qatar.
We prospectively studied IFN-γ and ADA levels in the pleural fluid of pat...
A 35-year-old Qatari man presented to our hospital with a 4-month history of mild abdominal pain, weight loss, and jaundice. He was found to have central intra-abdominal mass and a single testis in the scrotum. His investigations showed cholestatic jaundice and very high level of β -HCG (1131379 IU/L). CT scans of the chest and abdomen showed a hug...
We report a case of right-sided hemichorea associated with systemic lupus erythematosus (SLE) in a female patient who presented with involuntary movements of hand and foot, without any other manifestation of SLE. Further workup showed positive tests for antinuclear antibody, anti-Smith antibody, anti-dsDNA, and antiphospholipid antibody (aPL). The...
We report three male patients of younger age group presented with acute vein thrombosis of different sites, right lower limb, cortical venous sinuses thrombosis with cerebral vascular accident and third case is mesenteric vein thrombosis. All patients were Vegetarian, had low level of cobalamin with marked hyper homocysteinemia with normal serum an...
Objectives
The aim of this study was to evaluate the appropriateness of piperacillin/tazobactam (Tazocin®; Pfizer, New York, NY) usage in our hospital.
Subjects and methods
This retrospective study was designed to involve all patients admitted to Hamad General Hospital and prescribed piperacillin/tazobactam as an empiric therapy from January 1 to...
We report a case of parathyroid hormone-related protein–mediated hypercalcemic crisis in a 36-year-old pregnant woman, who was admitted to women hospital with recurrent vomiting and epigastric pain. She was diagnosed with uterine fibroid since the first month of her pregnancy, but the pregnancy had been uneventful. Serum calcium was 4.8 mmol/l, whi...
There is limited information about peritoneal tuberculosis in Qatar. This retrospective study aimed to review our experience with peritoneal tuberculosis in patients admitted to Hamad general hospital over a period of 5 years, from 2005 to 2009, with emphasis on presentation, investigation, diagnosis and therapeutic outcome. Fifty-four patients wit...
This study was conducted at Hamad General Hospital to determine the incidence of fungal peritonitis and to describe its clinical and microbiological findings in patients undergoing continuous ambulatory peritoneal dialysis in Qatar.
The medical records of these patients between 1 January 2005 and 31 December 2008 were retrospectively reviewed and t...
Escherichia coli (E. coli) was isolated from the pleural space of two patients; the irst one was a 32-year-old
Nepali man who was healthy before, presented with 15 day fever and cough. Chest x-ray showed left-sided
pleural effusion. After diagnostic workup, he was diagnosed to have E. coli parapneumonic empyema. In addition
to the antibiotics and...
Neurocysticercosis is the most common parasitic infection of the central nervous system. It is a major cause of seizures in developing countries, especially in the Indian subcontinent and most of Asia, Latin America and Africa. It is increasing in prevalence in Muslim countries, especially in the Gulf region reflecting the demographics of these cou...
We report a case of Enterococcus gallinarum meningitis in a 53-year-old female who was admitted to our hospital with a fever, headache, and consciousness disturbance one week after a life-saving craniotomy operation. There was obvious neck stiffness; lumber puncture was performed and cerebrospinal fluid parameters were consistent with bacterial men...
We conducted a one-year observational study from July 2007 to June 2008 to describe the epidemiology of bacteraemia at Hamad general hospital. During this period, a total of 452 episodes of bacteraemia occurred, which corresponds to a rate of 19/1000 hospital admissions. Most patients 58.8% (266/452) had community acquired bacteraemia, and primary...
We report an unusual association of pulmonary tuberculosis with moyamoya syndrome in a 30-year-old Filipino female who was admitted to our hospital with a 1-week history of fever and cough. Chest X-ray showed widespread bilateral consolidation with cavity, whereas sputum was positive for acid fast bacilli (AFB). Two weeks after starting antitubercu...
A 42-year-old Indian man received 450 mg rifampicin (RIF) and 150 mg isoniazid (INH) daily after being diagnosed of a latent tuberculosis infection. Baseline serum aminotransferase and total bilirubin levels were within normal limits. On day 31 of treatment, the patient experienced epigastric discomfort and general malaise and one week later he dev...
A 40-year-old man was admitted with a 6-day history of fever and abdominal pain. His right upper quadrant was tender on palpation. A blood smear revealed trophozoite forms of Plasmodium vivax and Plasmodium falciparum. Abdominal ultrasound findings were consistent with acute acalculous cholecystitis. He was treated successfully with quinine and dox...
This is a report of a case of blackwater fever in a 28-year-old Nigerian man who was admitted to hospital with fever, jaundice and passing dark urine. Abdominal examination revealed splenomegaly and an examination of the peripheral smear of the patient showed the ring form of the trophozoites of Plasmodium falciparum (P. falciparum). Serum creatini...
A case of typhoidal acalculous cholecystitis is described in a 31-year-old Indian man, who was admitted with 4-day fever, abdominal pain, diarrhea and vomiting. On examination, he looked ill, but was conscious and febrile with icteric sclera. The right upper quadrant of the abdomen was tender. Investigations showed high liver enzymes with high tota...
Background: There is limited information about the clinical profile of hyponatraemia in Qatar.
Objectives: The aim of this study was to describe the clinical presentation and aetiology of moderate and severe hyponatraemia in patients admitted to Hamad general hospital.
Patients And Methods: This descriptive observational hospital-based study was...