Fabrizio Margheritini

Fabrizio Margheritini
Italian University of Sport and Movement "Foro Italico"

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70
Publications
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Publications

Publications (70)
Article
A trend within the orthopedic community is rejection of the belief that “one size fits all.” Freddie Fu, among others, strived to individualize the treatment of anterior cruciate ligament (ACL) injuries based on the patient’s anatomy. Further, during the last two decades, greater emphasis has been placed on improving the outcomes of ACL reconstruct...
Article
Full-text available
Purpose: To establish recommendations for diagnosis, classification, treatment, and rehabilitation of posteromedial corner (PMC) knee injuries using a modified Delphi technique. Methods: A list of statements concerning the diagnosis, classification, treatment and rehabilitation of PMC injuries was created by a working group of four individuals. Us...
Article
PurposeThe management of posterolateral corner (PLC) injuries has significantly evolved over the past 2 decades. The purpose of this study was to determine the current worldview of key concepts on the diagnosis, treatment strategy, and rehabilitation for patients presenting with PLC injuries.MethodsA 12-question multiple-choice online survey was de...
Chapter
Bicruciate (anterior cruciate ligament (ACL)/posterior cruciate ligament (PCL)) lesions are rare, usually are caused by closed knee dislocations, and often are associated with peripheral injuries. The result of combinated anterior and posterior cruciate ligament lesions is a painful and debilitating knee instability that involves a discomfort for t...
Article
Full-text available
Purpose To develop a statement on the diagnosis, classification, treatment, and rehabilitation concepts of posterolateral corner (PLC) injuries of the knee using a modified Delphi technique. Methods A working group of three individuals generated a list of statements relating to the diagnosis, classification, treatment, and rehabilitation of PLC in...
Article
In skeletal muscle, which mainly contains postmitotic myonuclei, it has been suggested that telomere length remains roughly constant throughout adult life, or shortens in response to physiopathological conditions in muscle diseases or in the elderly. However, telomere length results from both the replicative history of a specific tissue and the exp...
Chapter
The posterior cruciate ligament (PCL) is the primary stabilizer of the knee joint and is the major restraint to posterior tibial translation. PCL insufficiency after the ligament’s rupture modifies the knee kinematics and may result in functional limitations in sports and daily activities. The management of PCL injuries remains a matter of debate,...
Article
Osteotomies around the knee are well-recognized treatments for unloading the affected compartment in cases of lower limb malalignment. There are few papers in the literature describing the outcomes of distal femoral osteotomy (DFO), as compared with the studies reporting on high tibial osteotomy (HTO), probably because valgus malalignment is less c...
Chapter
Injury to the posterolateral ligament structures of the knee is uncommon and frequently related to high-energy trauma and knee dislocations. Chronic grade 3 posterolateral injuries usually are seen in combination with chronic cruciate ligament injuries. It has been shown that untreated grade 3 posterolateral corner injuries are a major cause of fai...
Book
Knee ligament injuries are very common and are frequently sports related, although they may arise from trauma experienced during everyday activities. This book provides in-depth descriptions of the extra articular surgical techniques that may be employed when performing ligament reconstruction in patients with injuries involving the posterolateral...
Chapter
Abstract The PCL is considered an intra-articular and extra-synovial structure and its dimensions have been well described. Its length is 32–38 mm with a cross-sectional area of 11 mm 2, and the bony insertion sites are three times larger than its mid-substance [11]. The average area of the femoral footprint of the anterolateral (AL) bundle is 1...
Chapter
Posterior cruciate ligament (PCL) reconstruction has gained a great interest in the scientific community over the last decades. Despite this increasing interest, the management of PCL injuries remains a matter of debate, largely due to the lack of prospective studies delineating the true natural history of the injury and the absence of randomized t...
Article
Several techniques for posterior cruciate ligament reconstruction have been developed. The purpose of this paper is to present a new surgical technique that provides greater anatomical femoral fixation avoiding the sharp angle made by the graft at the exit of the femoral tunnel. Level of evidence V.
Chapter
Knee injuries are common and account for 15–50% of all sports injuries, 40% of which are ligamentous in nature [1]. Historically, the athletic population has been considered at risk for injuries involving the posterior cruciate ligament (PCL), but, interestingly, the reported incidence of these lesions is relatively low. However, PCL injuries are m...
Chapter
Full-text available
Ligaments are specialized connective tissues whose biomechanical properties allow them to adapt to and carry out the complex functions required of the body. While ligaments were once thought to be inert, it is now recognized that they are in fact responsive to many local and systemic factors which influence their performance within the organism. In...
Chapter
A careful and precise examination of the knee is mandatory for correct diagnosis, and fundamental for decision-making. It must be preceded by a complete patient history in order to address the clinical examination, even if symptoms are often non-specific. In addition, the clinical examination must be bilateral and well standardized. Every surgeon m...
Article
Full-text available
The human acetabulofemoral joint is commonly modelled as a pure ball-and-socket joint, but there has been no quantitative assessment of this assumption in the literature. Our aim was to test the limits and validity of this hypothesis. We performed experiments on four adult cadavers. Cortical pins, each equipped with a marker cluster, were implanted...
Article
Full-text available
The complete isolated rupture of the popliteus tendon has been described as a rare injury and this report describes the case of a 31-year-old soccer player who sustained a partial rupture of the popliteus tendon during a game. The injury was suspected clinically and at MRI but confirmed only by the arthroscopic examination. The treatment consisted...
Article
The human hip joint is normally represented as a spherical hinge and its centre of rotation is used to construct femoral anatomical axes and to calculate hip joint moments. The estimate of the hip joint centre (HJC) position using a functional approach is affected by stereophotogrammetric errors and soft tissue artefacts. The aims of this study wer...
Article
It has recently been postulated that a variety of growth factors may be released from cancellous bone after an acromioplasty. The aim of this study was to demonstrate the presence of growth factors in the subacromial space after acromioplasty. Between October 2006 and March 2007, 23 patients underwent arthroscopic acromioplasty. A sample of at leas...
Article
Rapid chondrolysis after partial arthroscopic lateral meniscectomy has been seldom reported in literature. Considering the relatively high number of partial lateral meniscectomy performed, we cannot understand why this complication is so rare. The purpose of this paper is to report a series of athletes developing a chondrolysis associated with post...
Article
The separation of a bipartite patella combined with quadriceps tendon rupture is a rare injury. Up to now, only 2 cases are reported in the literature. In this report we describe the case of a man, 71 years old and with no underlying disease, who presented diagnostic difficulties. The treatment of quadriceps tendon suture to the patella and excisio...
Chapter
The community of middle-aged and sport-active patients is growing. There is increased interest in high-impact or high-risk sports and these activities bring with them concomitant trauma to bones, joint surfaces, and soft tissue. Epidemiological studies from the early 1990s investigated the incidence of knee ligament injuries in the United States. T...
Article
We report a full arthroscopic inlay reconstruction technique to avoid the morbidity of traditional open inlay procedure. With the transeptal approach a trough is created arthroscopically at the anatomical tibial insertion of the PCL, which must fit with the patellar bone block of a quadriceps tendon autograft. The bone plug is harvested with two no...
Article
Soccer is the world's most popular organised sport with over 200 million males and 21 million females registered with the Fedeation Internationale de Football Association [International Football Federation (FIFA)]. Despite the widespread distribution of this sports activity and the fact that the knee is the second most frequent location of injury [...
Article
Tissue allografts allow the orthopaedic surgeon to reconstruct ligament without having to harvest additional tissue from the patient, which can eliminate donor tissue site morbidity and reduce surgical time. Despite some good clinical reports, there is still much to be learned about the biological aspects of the remodelling and incorporations of al...
Article
To review a series of tears of the posterior cruciate ligament (PCL) in order to understand its healing process, as well as to identify prognostic factors. Prospective study. Eighteen patients with isolated or combined PCL tears were evaluated and followed-up for 1 year after their initial injury. Magnetic resonance imaging (MRI) scans and stress r...
Article
Clinical success of posterior cruciate ligament (PCL) reconstruction continues to lag behind that of its anterior counterpart. The tibial site of PCL graft fixation has been a focus of recent research. This study examined the effect of combined distal and proximal tibial fixation on the ability of a transtibial PCL reconstruction to restore intact...
Article
The syndrome of the snapping popliteus tendon is a rare cause of lateral knee pain and may be difficult to diagnose, leading to patients undergoing inappropriate therapy or surgical intervention. In this report, we describe the arthroscopic findings of the snapping popliteus tendon. Two men and 1 woman presented complaining of pain and a snapping s...
Article
Full-text available
Functional adaptations of patients with posterior cruciate ligament deficiency (grade II) are largely unknown despite increased recognition of this injury. Posterior cruciate ligament-deficient subjects (grade II, 6- to 10-mm bilateral difference in posterior translation) will present with neuromuscular and biomechanical adaptations to overcome sig...
Article
The arthroscopic transeptal approach to the posterior joint spaces is an advanced technique that requires arthroscopic experience and knowledge of posterior knee anatomy. The main advantage this approach provides is superior access, including a broader field of vision and ample room for surgical instruments, to the posterior compartments. Therefore...
Article
The objective of this study was to evaluate the bone mineral density (BMD) of the proximal tibia in the area adjacent to the fixation of the posterior cruciate ligament (PCL) and compare with the BMD in a similar area at the ideal site for anterior cruciate ligament fixation. Twenty healthy male subjects, undertaking similar daily physical activity...
Article
We report a case of a rare neurological tumour arising in the knee joint with no apparent connection to the major nerve trunks in the area. After the patient failed to improve through rehabilitation, surgery was performed, revealing a concomitant tear of the medial meniscus as well as a mass which was excised through an external supero-medial incis...
Article
The tibial inlay technique for posterior cruciate ligament reconstruction has been proposed to provide a more anatomic reconstruction because it eliminates the sharp turn in the graft as it exits the proximal margin of the tibial tunnel in the transtibial technique. Reconstruction of the posterior cruciate ligament using the tibial inlay technique...
Article
The posterior cruciate ligament has become an increasingly popular subject of orthopaedic research and debate. While biomechanical studies have shown its role as major stabilizer of the knee, clinical studies have shown its increasing incidence. Furthermore, injuries to posterolateral structures are frequently encountered and failure to recognize a...
Article
Different authors are currently debating the validity of various techniques for anterior cruciate ligament (ACL) reconstruction. Our group has thus designed a study aimed at determining which postoperative pain management protocol of locoregional analgesia might be most adequate for such procedure. Patients were randomly allocated in three groups o...
Article
The objective of this study was to evaluate the efficacy of different stress radiography techniques in quantifying a posterior cruciate ligament (PCL) lesion. Prospective serial study. Sixty patients with subacute or chronic PCL injuries, confirmed using magnetic resonance imaging (MRI) or arthroscopic evaluation, were enrolled in this study. The p...
Article
The posterior cruciate ligament is one of the most controversial issues in sports medicine. There is no consensus in the literature with respect to its incidence, natural history, and treatment indications. Injury evaluation is often underestimated, with the result of misdiagnosed injury or wrong treatment. This contribution reviews the principles...
Article
Septic arthritis is a medical emergency that can lead to rapid joint destruction. Staphylococcus and Streptococcus are the predominant organisms. The key to success is early diagnosis, system antibiotic therapy, and decompression of the affected joint. The aim of this article is to review the most up-to-date knowledge about this topic, providing us...
Article
Anatomic graft fixation in anterior cruciate ligament reconstruction has been shown to be extremely important for achieving acceptable postoperative knee stability. Different methods have been proposed for customizing graft length, so that anatomic graft fixation is obtained at the native anterior cruciate ligament site. A technique has been descri...
Article
The synovial cyst within the posterior cruciate ligament is uncommon lesion with a no specifically clinical onset and difficult visualization because of their location. The posterior arthroscopic approach is not always succesful in localising and removing the cyst. The aim of this case report is to present the use of the trans-septal arthroscopic t...
Article
Recently, the posterior cruciate ligament (PCL) has become an increasingly popular subject of orthopaedic research and debate. In the past several years, anatomic and biomechanical studies have provided invaluable information concerning the structure and function of the PCL. However, many aspects of PCL injury are still not fully understood. Diagno...
Article
Snapping with pain the lateral aspect of the knee can be caused by various affections. These pathologies include iliotibial band friction syndrome, lateral meniscal tear, osteochondritis dissecans, symptomatic degenerative joint diseases, lateral collateral ligament lesion, subluxation of the proximal tibio-peroneal syndesmosis, tendonitis of popli...
Article
Recently, the posterior cruciate ligament (PCL) has become an increasingly popular subject of orthopaedic research and debate. In the past several years, anatomic and biomechanical studies have provided invaluable information concerning the structure and function of the PCL. However, many aspects of PCL injury are still not fully understood. Diagno...
Article
Our purpose was to prospectively analyze serial changes in magnetic resonance imaging (MRI) signal of the bone-patellar tendon-bone autograft when used for posterior cruciate ligament (PCL) reconstruction and to retrospectively determine at mid-term follow-up the relationship between MRI graft appearance and clinical stability in patients who have...
Article
We studied changes in C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) to establish normal values after uncomplicated anterior cruciate ligament (ACL) reconstruction. The levels of CRP and ESR were determined by serial measurements in 45 consecutively treated patients. Blood samples were collected before surgery and on postoperativ...
Article
To retrospectively evaluate 15 consecutive patients who underwent simultaneous isolated, arthroscopically assisted anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) reconstruction. Type of Study: Case series. A bone-patellar tendon-bone autograft was used as the PCL substitute and doubled hamstring tendons were used as the ACL...
Article
The purpose of this study was to investigate the outcomes of 2 different methods of femoral fixation for arthroscopically assisted anterior cruciate ligament (ACL) reconstruction. Type of Study: Double-blind prospective study. Fifty-five patients were prospectively evaluated at 2-year follow-up. In group A, 24 patients underwent arthroscopic ACL re...
Article
Infection after total hip or knee arthroplasty is a major concern for the orthopedic surgeon. Because postoperative recovery in patients undergoing hip or knee replacement is always characterized by a shift in basal laboratory parameters, the value of the routine use of these parameters in the detection of this major complication is controversial....
Article
This study compared postoperative bleeding during anterior cruciate ligament (ACL) reconstruction following notchplasty by power instrumentation with that following radiofrequency. Between January 1998 and April 1998 we prospectively divided 24 consecutive patients undergoing arthroscopic ACL reconstruction with bone-patellar tendon-bone autograft...
Article
Full-text available
Injuries to the posterior cruciate ligament (PCL) have traditionally been reported to be rare but in the last decade, this ligament has captured the attention of orthopaedic surgeons world-wide. While new or improved surgical techniques involving the PCL have achieved attractive results, accurate evaluation of the PCL-deficient knee still remains a...
Article
We present the outcome of a mould arthroplasty implanted for a congenital hip dysplasia in 1955 to revise a previous cup arthroplasty. This type of prosthesis, which has been developed on the basis of the concept of Smith-Peterson, by Prof. Marino-Zuco in Rome in the early 1940s, showed excellent results and was widely used until the advent of Char...
Article
The healing process of tendon grafts used in cruciate ligament reconstruction is called ligamentization. The tendon structural architecture changes progressively into the histological appearance of normal ligament. Amiel and Clancy have demonstrated that this process is time-dependent in anterior cruciate ligament (ACL) reconstruction, the tendon g...
Article
We evaluated the utility and the safety of arthroscopy for diagnosing and treating symptoms in patients with osteoarthritis (OA) of the hip. We studied 133 patients consecutively treated for hip OA, using a modified Harris Hip Score (HHS) for the clinical assessment: There were no related complications or infections. At an average follow-up of 18 m...
Article
Full-text available
This report describes a rare intra-articular lipoma of the hip which developed in a 31-year-old male after a football injury. A plain X-ray and an MRI scan of the hip showed no bony abnormalities. After the patient failed to improve with a rehabilitation programme, arthroscopy of the hip was performed, revealing a lump in the acetabular fossa assoc...
Article
The fundamental role played by macrophages and fibroblasts of the synovial-like membrane in aseptic hip prosthesis loosening (AHPL) has recently been confirmed by numerous studies. In this study, the activity of these cells in patients with prosthetic loosening was analyzed by evaluating the main markers of fibroblast and macrophage activation in s...
Article
The authors analyse the implications connected with the prosthetic surgery in RA, evaluating surgical approaches, biomaterials and most recent data concerning osteointegration. Prosthetic surgery must be seen in the context of a wider medical strategy, involving rheumatologist and physiatrist, for a more rational approach to optimise surgical and r...
Article
The Authors carried out a clinical and electromyographic study on two groups of patients undergoing total hip replacement with two different surgical approaches, evaluating the evolution of the clinical results at three and fifteen months after operation and comparing the same to the electromyographic results of the muscles involved during surgical...
Article
The authors conducted two studies to demonstrate the presence of a relationship between osteoporosis and arthrosis: the first study was experimental involving thirty femoral heads removed during hip arthroplasty, and the second was a clinical study conducted on forty patients with coxarthrosis. The results obtained confirm how the presence of one o...
Article
The total hip replacement operation needs a specific surgical approach and a wide exposure of the hip joint. In the last century, many of them have been proposed for this type of operation, with variations that were more or less significant and important. With time only some types of surgical approaches have been selected and others have proved to...
Article
A stress fracture is a disruption in the continuity of normal bone occuring without a specific history of trauma. The initial sympton is diffuse heel pain, meanwhile the initial X-rays cannot show any osseus abnormality. It is often necessary a total-body scintigram to determine the lesion. Also MRI is able to demonstrate the bony injury. The autho...
Article
We report a study on how the bone-implant interface of 20 T.H.A. failed because of aseptic loosening. The aim of this study was to look for the mechanism that promotes the activation of the cell-population located in the tissues at the interface. We have demonstrated, with the help of cytochemical and enzymatic techniques, that cell-activation can...