Fabiano Antonio Cadioli

Fabiano Antonio Cadioli
São Paulo State University | Unesp · Departamento de Clínica e Cirurgia e Reprodução Animal

Associated Professor (Habilitation professorship), DVM, MSc, PhD

About

73
Publications
19,515
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346
Citations
Additional affiliations
April 2006 - present
Universidade Estadual Paulista
Position
  • Large Animal Internal Medicine Professor; Post graduation Professor
March 2006 - present
São Paulo State University
Position
  • Animal trypanosomiasis
March 2006 - December 2014
São Paulo State University
Position
  • Patogenicity evaluation of Trypanosoma evansi and T. vivax in domestic and laboratory animals
Education
March 1992 - February 1996
São Paulo State University
Field of study
  • Veterinary Medicine

Publications

Publications (73)
Article
It was investigated how many cattle become infected with Trypanosoma vivax by subcutaneous (SC), intramuscular (IM) and intravenous (IV) routes, using the same syringe and needle from an animal with acute T. vivax infection. Besides, the T. vivax viability in 109 injectable veterinary drugs (antibiotics, antiparasitics, reproductive hormones, vitam...
Article
Full-text available
Trypanosoma vivax outbreaks have been reported with increasing frequency worldwide, causing significant economic losses in livestock. Though several studies have suggested that cytokine responses may influence infection caused by Trypanosoma sp., their exact role remains unclear and may vary according to the animal species and parasite strain. The...
Article
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Although co-infections of Trypanosoma vivax, Anaplasma spp., and Babesia spp. have been reported, knowledge gaps remain that need to be addressed. The present study evaluated the efficacy of enrofloxacin (7.5 mg/kg) against A. marginale in naturally infected cattle and cattle experimentally co-infected with T. vivax by observation of the variation...
Article
Trypanosoma vivax causes bovine trypanosomosis in cattle and resulting in economic losses to farmers. In Brazil, shared contaminated materials is the main transmission pathway. To evaluate the effectiveness of different disinfectants for T. vivax, in vitro and in vivo analyses were performed. At the laboratory, 21 disinfectants were tested. The dis...
Article
Full-text available
Trypanosoma vivax infections cause nonspecific clinical signs in cattle associated with aparasitemic intervals, making disease diagnosis a challenge. In Brazil, diminazene aceturate and isometamidium chloride (ISM) are available to treat bovine trypanosomosis. The objective of this study was to follow-up, by molecular and serological techniques, da...
Article
Bovine trypanosomosis has been spreading in Brazil. In the present study, we evaluated the spatial distribution, prevalence and risk factors of this disease in the state of in Goiás, Brazil, and performed both molecular and phylogenetical analyses of Trypanosoma vivax. A total of 4,049 blood samples were collected from cattle for a period of two ye...
Article
In this study, we evaluated the therapeutic efficacy of diminazene diaceturate at a dose of 7 mg/kg (DA), imidocarb dipropionate at 4.8 mg/kg (IMD), isometamidium chloride at 0.5 and 1.0 mg/kg (ISM 0.5 and ISM 1.0) and combinations applied through different methods to treat Trypanosoma vivax in experimentally infected calves. Thirty male Girolando...
Article
The aim of the present study was to compare the infection capacity of Trypanosoma vivax experimentally inoculated through different routes in calves naturally infected with latent Anaplasma marginale. On Day 0 of the study, 25 calves (breed: Girolando) were divided into five groups. The first four groups of five calves each received approximately 1...
Article
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Livestock infections by Trypanosoma vivax have been occurring with increasing frequency, mainly due to the presence of animals with subclinical infections and without apparent parasitaemia, making diagnosis challenging. The aim of the present study was to evaluate several techniques used for T. vivax diagnosis in order to assess the best way of usi...
Article
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The objective of this study was to investigate the occurrence of trypanosomiasis in a dairy farm in municipality of Timon, State of Maranhão, Brazil. The owner reported abortus, births of weak calves, and mortality of adult animals with progressive weight loss. Visits to the property were carried out to obtain the history, realize animal examinatio...
Article
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Trypanosoma vivax is a parasite widespread across Africa and South America. Immunological methods using recombinant antigens have been developed aiming at specific and sensitive detection of infections caused by T. vivax. Here, we sequenced for the first time the transcriptome of a virulent T. vivax strain (Lins), isolated from an outbreak of sever...
Conference Paper
Full-text available
Trypanosoma vivax causa lesões no encéfalo mesmo na ausência de sinais neurológicos [a] Resumo O Trypanosoma vivax causa doença em ruminantes na África, América Central e América do Sul. O parasita tem sido incriminado como causador de alterações neurológicas em ruminantes. Este estudo foi aprovado pela Comissão de Ética no uso de animais da FCAV/U...
Conference Paper
Full-text available
Trypanosoma vivax spreads in herds worldwide mainly by the introduction of animals in chronic phase of the infection, where parasitaemia is low and intermittent, which makes diagnosis challenging. Direct T. vivax visualization still the more widely used method for the disease diagnosis, but is inaccurate in low parasitaemia. The aim of the present...
Conference Paper
Full-text available
Trypanosoma vivax infections in livestock have been occurring with increasing frequency all over the planet, however the disease still poorly studied and some aspects of its pathophysiology remain obscure. Knowledge of the immune response profile is important not only for understand the host-parasite relationship, but also for the development of ne...
Article
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Infections by Trypanosoma vivax cause great losses to livestock in Africa and Central and South Americas. Outbreaks due this parasite have been occurred with increasing frequency in Brazil. Knowledge of changes caused by T. vivax during the course of this disease can be of great diagnostic value. Thus, clinical signs, parasitemia, hematologic and b...
Article
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RESUMO Entomoftoromicoses são um grupo de enfermidades cosmopolitas causadas por Conidiobolus ssp e Basidiobolus haptosporus (B. ranarum) que afetam tanto o ser humano quanto animais, embora infecções em equídeos sejam pouco comuns. Entomophthorales são encontrados no solo, em folhas secas e parasitando insetos e aranhas e causam lesões piogranulom...
Research
Full-text available
O uso da qPCR para a detecção do T. vivax é técnica recente e esta é a primeira vez que é testada na detecção de isolado brasileiro. Os resultados obtidos indicam ser uma ferramenta útil para o diagnóstico precoce desta tripanossomíase, principalmente em animais com parasitemia não evidente, o que poderá contribuir em medidas de controle da dispers...
Article
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Nutritional secondary hyperparathyroidism is a metabolic disorder that commonly affects horses, but can also manifest in goats and pigs. The etiology is related to changes in serum calcium and phosphorus due to dietary imbalance, leading to hypersecretion of parathyroid hormone, and consequent hyperparathyroidism manifested by fibrous osteodystroph...
Article
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O hiperparatireoidismo nutricional secundario e um disturbio metabolico que acomete principalmente equideos, mas pode se manifestar em caprinos e suinos. A etiologia esta relacionada a alteracoes nas concentracoes sericas de calcio e fosforo devido a ingestao desbalanceada na dieta, levando a hipersecrecao do paratormonio e consequente hiperparatir...
Conference Paper
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LAMP NA DETECÇÃO DE ISOLADOS BRASILEIROS DE TRYPANOSOMA VIVAX » Á rea de pesquisa: PROTOZOOLOGIA » Instituição: Faculdade de Medicina Veterinária de Araçatuba/Unesp (FMVA) » Agência de fomento e patrocinadores: FAPESP Proc. 14/04066-9 T. vivax causa anemia, emaciação progressiva e morte em equinos, bovinos e outras espécies de ruminantes. A fase cr...
Article
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Lymphoma is the most prevalent neoplasia in dairy cattle. The etiology can be viral in animals affected by bovine leukemia virus (BLV) or be classified as primary. Lymphoma can affect several organs and according to the system involved, the clinical signs could manifest themselves in different ways. These tumors can be classified through macroscopi...
Conference Paper
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Trypanosoma vivax is a hemoprotozoa which infects a wide variety of wild and domestic ungulate animals causing important economic losses in cattle herds in tropical regions of Africa, Central and South America. The economic impact of this disease may reach 17% of the total herd. The aim of this study was to verify the humoral immune response of nat...
Article
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The Rhipicephalus (Boophilus) microplus is the main bovine ectoparasite and it is associated to a several diseases, causing economic losses to dairy and beef industry. The arose of commercial acaricides resistant population of R. microplus is a problem in many farms worldwide, causing US$ 7 billion losses each year. The properly use of each acarici...
Article
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Copper (Cu) is an essential microelement for mammals, however, when ingested in high amounts in a short or prolonged period can cause severe intoxication. The ability to accumulate Cu in tissues varies with the species and breeds within species. Among species affected, we highlight the sheep, and to a lesser extent, canine, porcine and bovine. Acut...
Article
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O cobre (Cu) é um microelemento essencial aos mamíferos, entretanto, quando ingerido em altas quantidades, num período curto ou prolongado, pode provocar uma intoxicação severa. A habilidade de acumular Cu nos tecidos varia de acordo com as espécies e com as raças dentro da própria espécie, dentre as espécies acometidas, destacam-se a ovina, e em m...
Article
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This is the first description of a Trypanosoma vivax outbreak in the state of São Paulo (municipality of Lins). Fever, jaundice, decreased milk production, weight loss, profuse diarrhea, abortion, anemia, leukocytosis and hyperfibrinogenemia were observed in the affected animals. Thirty-one cows and calves died out of a total of 1080 in the herd. T...
Article
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This study compared the hematological and serological analysis of diagnosis of canine ehrlichiosis. The survey of Ehrlichia canis was performed through the evaluation of blood smears from 150 dogs. The serological test was performed on 12 samples selected by the platelet count (less than 170,000 platelets / uL). Serologic testing was performed with...
Article
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An 18-year-old Quarter Horse mare presented with an 18 week history of dermatological lesions characterised by recurrent urticaria and recent signs of enlarged mammary glands, pyrexia, alopecia and intense pruritus. Haematological and serum biochemical analyses revealed anaemia, leucocytosis, thrombocytopenia and hyperfibrinogenaemia. Mammary disch...
Article
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An adult Girolando dairy cow with severe lethargy was presented for examination to the UNESP Veterinary Hospital, Araçatuba, Brazil. The cow had generalized lymph node enlargement, cachexia, severe signs of anemia, and decreased milk production. Analysis of the hemogram revealed severe nonregenerative anemia, as evidenced by markedly decreased RBC...
Conference Paper
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Introduction: The rectal temperature (RT) is the most diffused method for body temperature measure in Veterinary Medicine, being the mercury thermometer (HgT) considered the most precise, although you have to wait two minutes to obtain reliable RT and during this time the animal can become uneasy and break the HgT inside the rectum causing importan...
Conference Paper
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Introduction: The rectal temperature (RT) is the most diffused method for body temperature measurement in Veterinary Medicine, being the mercury thermometer considered the most precise, although you have to wait two minutes to obtain reliable RT, which is impracticable in face of a large animals number. In this case the digital thermometer (DigT) c...
Conference Paper
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Introduction: Digital affections are very frequent in cattle bringing about irregular distribution of weight, producing stress of joints, tendons and ligaments causing severe LAMENESS that could influence the production performance and causes important economic losses. Although this problem has been knew, the bovine foot radiographic changes were a...
Conference Paper
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Introduction: Bone marrow (BM) evaluation has proven to be a valuable diagnostic tool for the veterinary practitioner. It is indicated for patients with blood findings that suggest neoplastic conditions or in unexplained cytopenias, in which the CBC does not provide evidence of the normal performance of BM, and possible interferences in the hematop...
Conference Paper
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Introduction: Lamb disbudding is not a common procedure, but sometimes it is used for several purposes, including ANIMAL WELFARE and handling. In other hand, disbudding with fire-heated iron is a common procedure, but sometimes overenthusiastic application of it can lead to brain damage.
Article
The clinical efficacy of IV infusion of lidocaine for treatment of equine endotoxemia has not been studied. Hypothesis: Lidocaine infusion after exposure to lipopolysaccharide (LPS) will inhibit the inflammatory response and have inhibitory effects on the hemodynamic and cytokine responses to endotoxemia. Twelve horses. Two equal groups (n=6): sali...
Article
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O objetivo deste estudo foi determinar as concentrações séricas de imunoglobulina G, PT e de sua fração eletroforética γ globulina, assim como a atividade enzimática de GGT e ALP. Estabeleceu-se a possibilidade da atividade destas enzimas ser utilizada indiretamente como indicadoras de um adequado nível de proteção humoral e/ou como falha de transf...
Article
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The aim of this study was to determine the serum concentrations of immunoglobulin G, TP and the γ globulin electrophoretic fraction, as well as the enzymatic activities of GGT and ALP. This was done in order to explore the possibility of using changes in activities of these enzymes as indirect indicators of adequate humoral immunity and/ or failure...
Article
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The seroprevalence of Maedi-Visna in sheep from Araçatuba region - SP, was determined and correlated to age, gender, breed, or sheep production systems. Blood samples were collected from 444 sheep, aging from two to 12 year-old. Both sexes and different breeds were sampled in 20 farms of this region. Physical examination was performed in all animal...
Conference Paper
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INSTITUIÇÃO: FOA/UNESP ‐ CAMPUS DE ARAÇATUBA TEMA: Métodos de diagnósticos RESUMO: Trypanosoma spp. are Kinetoplastida:Trypanosomatidae protozoan which causes trypanosomiasis worldwide in humans, domestic and wild animals. Some of Trypanosoma spp. can be found at South America and the ones identified as responsible for causing losses in pecuary are...
Article
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The occurrence of Cryptosporidium in fecal samples of lambs was determined in order to test correlations among the type of animal raising, feces consistence, index of oocysts elimination, animal age, and molecular characterization of species and genotypes involved in this parasitism. A total of 460 fecal samples were collected from lambs during the...
Article
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This study established the electrophoretic profile of serum proteins of Wistar rats experimentally infected with Tripanosoma evansi. For such, 40 rats were allocated into eight groups of five animals. A group was kept as control (G1) and the others (G2 to G8) were intraperitoneally inoculated with 1.0 x 103 tripomastigote of T. evansi. Blood sample...
Article
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The goals of this study were to evaluate if hemoglobin played a role as adjuvant in experimental peritonitis in horses and could cause clinical and haematological alterations that could be used for diagnosis and prognosis of cases of peritonitis. Fifteen adult horses were randomly divided into 5 equal groups, which were injected intraperitoneally w...
Article
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Five adult donkeys were experimentally infected with Brazilian strain of Trypanosoma evansi originally isolated from a naturally infected dog to study the hematological biochemical and histopathological alterations during the evolution of the disease. The course of the experimental infection was followed up to 145 days. Hematological analyses of th...
Article
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negativas para a presença de anticorpos anti-T. evansi (Reação de Imunofluorescência Indireta -RIFI). Desses dez animais, quatro foram utilizados como testemunhos (G3) e os seis restantes constituíram os grupos G1 e G2. As ovelhas do G1 e G2 foram inoculadas via intravenosa, com cerca de 2,4 x 10 6 e 2,4 x 10 7 tripomastigotas de T. evansi, respect...
Article
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RESUMO Diminuição da concentração plasmática de glicose tem sido observada durante o curso da doença causada pelo T. evansi e pode ser decorrente da espoliação de glicose e nutrientes sangüíneos pelo parasita. O objetivo deste trabalho foi estimar o consumo de glicose, in vitro, pelo T. evansi, pelas hemácias de rato Wistar e pela associação de amb...
Article
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Physical, biochemical and cytological characteristics of the digital flexor tendon sheath synovial fluid were studied in nine clinically normal horses. It is a viscous, pale yellow, clear fluid, without flocculent material and does not clot at room temperature. Its hyaluronic acid mean concentration was 60.20mg/dL, glucose levels were similar to th...
Article
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Foram estudadas as características físico-químicas e citológicas do líquido sinovial da bainha tendínea digital de nove eqüinos hígidos. Verificou-se que o líquido é viscoso, amarelo claro, límpido, livre de partículas e que não coagula à temperatura ambiente. Sua concentração média de ácido hialurônico foi 60,20mg/dl, a taxa de glicose, similar à...
Article
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Os autores abordam a descrição morfológica da bainha tendínea sinovial digital dos eqüinos e sua função, bem como o processo de formação de seu líquido sinovial, indicando a importância do estudo de tal estrutura.
Article
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Objetivo: Descrever a ocorrência de abscessos na coluna vertebral de seis bezerros e d.ois cordeiros criados no Estado de São Paulo. Descrição: Os animais acometidos tinham entre 50 e 150 dias de idade. Os sinais clínicos eram caracterizados por ataxia e paralisia caudal à lesão compressiva da medula espinhal. Um bezerro apresentou abscesso no corp...
Article
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The authors report the morphological description of equine digital tendon sheath, its functions, how its synovial fluid is produced, and the importance of such study.
Article
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The clinical, surgical, and anatomopathologic findings of four cases of intussusception in cattle are described. In three cows it was observed jejunum intussusception with fatal obstruction, and in one cow, intussusception of the colon with partial obstruction. The presence of massive parasitism by Oesophagostomum sp. in two animals suggests the pa...