Evrim Karadag-Saygi

Evrim Karadag-Saygi
Marmara University · Department of Physical Medicine and Rehabilitation

Professor, MD

About

107
Publications
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586
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Publications

Publications (107)
Article
Full-text available
Small fiber neuropathy (SFN) is one of the main neurological manifestations in primary Sjögren’s Syndrome (pSS). For the detection of SFN, cutaneous silent period (CSP) measurement is gaining popularity recently due to its non-invasiveness and practical application. Evaluating SFN involvement in patients with pSS using CSP and evaluating its relati...
Article
Sjögren-Larsson syndrome (SLS) is a rare neurocutaneous disorder characterized by the presence of congenital ichthyosis, spasticity, and mental retardation. As with other rare genetic diseases, treatment is mainly symptomatic. Due to the absence of definitive treatment, lifelong follow-up and support of patients are important to improve the quality...
Article
Even though the effect of several factors on sit-to-stand (STS) performance of children with CP has been previously explored, the potential role of lower extremity selective control, trunk control and sitting function on the performance of STS has not been examined. This study aimed to investigate the association of trunk control and lower extremit...
Article
Full-text available
New molecular therapies are available for the treatment of spinal muscular atrophy (SMA) but early intervention is required. We report two cases that were diagnosed prenatally, where treatment with nusinersen was initiated within 7 h and three days respectively. The children were followed up for 13 months and almost six years respectively. Both chi...
Article
Introduction:This study aimed to evaluate the validity of the PASE in stroke patients by comparing its scores with activity data derived from an accelerometer. Materials and Method:25 patients with stroke who walked independently or with an assistive device were included in the study. An accelerometer was held on participants’ non-paretic hips on M...
Article
Introduction: Patients with Duchenne muscular dystrophy (DMD) have lost their access to on-site rehabilitation due to the COVID-19 pandemic. Telerehabilitation can be a viable approach for these patients to protect their muscle strength and functional status. The aim of this study is to compare telerehabilitation with home-based video exercises....
Article
Background Neurological involvement has a great importance in the clinical spectrum of primary Sjögren’s syndrome (pSS) (1). The presence of small fiber neuropathy (SFN), which cannot be detected in routine electrophysiological examinations, causes the peripheral nervous system involvement to be underestimated in the course of the disease and cause...
Article
Background/objective: With the COVID-19 (coronavirus disease 2019) pandemic, telemedicine applications gained momentum, and clinicians tried to develop various musculoskeletal examination methods to be used in telemedicine visits. The aim of this study is to investigate the interrater reliability, acceptability, and practicality of the real-time v...
Article
Objective: The Modified Ashworth Scale, the Modified Tardieu Scale, and measuring the passive range of motion is commonly preferred examination tools for spasticity in cerebral palsy (CP). Ultrasonography has become increasingly used to provide relevant insight into spastic muscle morphology and structure recently. It was aimed to reveal associati...
Article
The quick motor function test (QMFT) is used to evaluate Pompe patients' motor function. This study aims to evaluate the convergent validity and reliability of the cross-culturally adapted Turkish version of QMFT in patients with Duchenne muscular dystrophy (DMD). Twenty-eight patients diagnosed with DMD were included in the study. The QMFT was tra...
Article
Background: Respiratory failure is the leading cause of mortality in spinal muscular atrophy type 1 (SMA1) children. The current study aims to evaluate the effect of nusinersen treatment on respiratory outcome of the patients with SMA1. Methods: In this retrospective, single-center study, 52 SMA1 patients treated with nusinersen were included in...
Article
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Objectives: This study aims to assess psychosocial functioning in relation to lesion level and ambulatory status in children with spina bifida (SB) and compare them to their peers. Patients and methods: Between March 2013 and May 2013, a total of 31 patients with SB (11 males, 20 females; mean age: 9.4 years; range, 6 to 14.7 years) and 36 typicall...
Article
Background: Postural and aerobic exercises are essential in rehabilitation in CF. The aim of this study is to examine the effect of telerehabilitation on the quality of life, depression and anxiety levels of children with CF and their caregivers' mood and anxiety levels. Materials and methods: Patients between the ages of 6-13 with CF were rando...
Article
Introduction Airway clearance techniques, which include positive expiratory pressure (PEP) devices, are essential in the pulmonary rehabilitation of cystic fibrosis (CF). Bottle-PEP is a low-cost but an effective alternative. Objective The aim of this study is to document the sustainability and safety of Bottle-PEP therapy as a home rehabilitation...
Article
Abdominal spasms are involuntary contractions that can be caused by denervation due to spinal cord injury. We present a case that benefited from botulinum toxin injections. A 42-year-old male patient was followed up due to spinal cord injury that developed secondary to burst fracture in the 6th thoracic vertebra as a result of falling off the train...
Article
Background: To describe and understand the experiences and beliefs of caregivers of children with cerebral palsy following botulinum toxin injection. Methods: A descriptive case study approach with focus group interviews was employed. A semi-structured questionnaire was conducted to collect data. Twenty-one caregivers of children (3-13 years old...
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Aim: This study aims to reveal the problems faced by families of children with spinal muscular atrophy (SMA), by evaluating their care burden, needs, and expectations. Materials and methods: The participants were the primary caregivers of 34 children between the ages of 0 and 18 years diagnosed with SMA. Thirteen children were diagnosed with typ...
Article
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Objectives: The aim of this study was to investigate the impact of ankle-foot orthoses (AFOs) on the balance and gait and to compare the effects of hinged AFOs with solid AFOs on balance in patients with cerebral palsy (CP). Patients and methods: Between January 2015 and January 2016, 19 hemiplegic children with CP (11 males, 8 females; mean age...
Article
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Objectives: This study aims to investigate the effects of postural exercises as an adjunct to chest physiotherapy program on respiratory function, exercise tolerance, quality of life (QoL), and postural stability in patients with cystic fibrosis (CF). Patients and methods: In this single-blind, randomized-controlled trial, 19 pediatric CF patients...
Article
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Spasticity is the most common motor disturbance in cerebral palsy (CP). Lock-down in the COVID-19 outbreak has profoundly changed daily routines, and similarly caused the suspension of spasticity treatment plans. Besides, the delay in botulinum toxin (BoNT) injection, which is important in the management of focal spasticity, led to some problems in...
Article
Aim: This study aims to investigate reliability of quantitative ultrasound measurement of the flexor dig-itorum superficialis (FDS) and flexor digitorum profundus (FDP) muscles in stroke. Materials & methods: Patients with a history of stroke were recruited. FDP and FDS muscles on both upper extremities were investigated with ultrasound. Two indepe...
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Objective:The aim of this study is to investigate the frequency of fractures and related factors in children with spina bifida who were followed up in our hospital.Materials and Methods:By retrospectively examination of the medical records of 450 patients with spina bifida, who were followed up by our clinic between 2000 and 2018, the patients were...
Article
Aim We aim to describe the demographic characteristics, etiology, neurophysiology, imaging findings, treatment, prognosis, and prognostic factors of acute flaccid myelitis. Methods The clinical data, laboratory test and, magnetic resonance imaging (MRI) results of pediatric patients diagnosed with acute flaccid myelitis according to the Centers fo...
Article
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Background Chest physiotherapy (CP) is a recommended treatment modality in primary ciliary dyskinesia (PCD). Objective Primary aim was to compare the efficacy and safety of the conventional chest physiotherapy (CCP) and oscillatory positive expiratory pressure therapy (OPEPT). Secondary aims were to compare the exacerbation rate, time until the fi...
Article
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Background: Chest physiotherapy (CP) is a recommended treatment modality in primary ciliary dyskinesia (PCD). Objective: Primary aim was to compare the efficacy and safety of the conventional chest physiotherapy (CCP) and oscillatory positive expiratory pressure therapy (OPEPT). Secondary aims were to compare the exacerbation rate, time until the f...
Article
Purpose Children with low lumbar and sacral level myelomeningocele are expected to be community ambulators. However, they do not always meet the expected ambulation level by the time they reach adulthood. The purpose of this study is to investigate daily activity energy expenditure and physical activity levels of these patients in daily routine. M...
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Idiopathic brachial neuritis (IBN) is an uncommon clinical disorder with an onset of acute, aching shoulder pain, followed by progressive muscle weakness and atrophy of the shoulder girdle and upper extremity. A 47-year-old male patient presented with an onset of acute left shoulder pain, which has lasted for two months. On physical examination, he...
Article
Despite sore throat exists in the product characteristics of abobotulinum toxin A as one of the side effects, no available reports of sore throat after abobotulinum toxin A injection for adult upper limb spasticity could be found in the literature to guide physicians for the management. Herein, we report a case of poststroke spasticity who develop...
Article
Study Design Prospective single-blind, randomized controlled study. Introduction Children with perinatal brachial plexus palsy (PBPP) have motion limitations in the affected upper extremity. Modified constraint-induced movement therapy (mCIMT) is one of the treatment options used for the improvement of the function of the affected limb. Purpose o...
Article
Objectives: Comparison of self-rating method and telephone interview method on outcome measures' results. Methods: This cross-sectional study included 100 patients aged 18-40 years who applied to Physical Medicine and Rehabilitation outpatient clinics with mechanical low back pain. Outcome measures [Oswestry Disability Index (ODI), Roland Morris...
Article
Background: Dynamic lycra splints are proposed to modify hypertonicity due to their characteristics – neutral warmth, circumferential pressure, and creating a low-intensity prolonged stretch on hypertonic muscles – to contribute to increased sensory awareness of the involved limb. Objectives: The aim of this study was to investigate the effects of...
Article
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Objective: To assess static and dynamic postural stability changes in children with high sacral level spina bifida. Methods: Thirty-five children with high sacral level spina bifida and 35 age-matched healthy controls were enrolled. Their lower extremity muscle strengths and static and dynamic postural stability parameters were measured with the us...
Article
Purpose: To investigate the effect of caregiver burden, resilience, and quality of life of the parents of patients who are followed-up in a tertiary pediatric rehabilitation clinic. Design and methods: This is a correlational cross-sectional study. Parents of patients who attend to utilize pediatric rehabilitation outpatient clinics of a tertiar...
Article
Background: Dynamic Gait Index (DGI) is a performance-based tool can be applied in a short time and evaluates dynamic balance and gait ability. Research question: Is the DGI valid and reliable for assessing gait and balance disorders in children with hemiplegic cerebral palsy (CP)? Methods: Sixteen children with hemiplegic CP (5 females, 11 ma...
Article
Introduction: Caregiver burden impacts both the social and economic framework of society. Cystic fibrosis (CF) causes significant caregiver burden, but the current data is scarce. In the case of primary ciliary dyskinesia (PCD), even less is known. This study aims to compare the caregiver burden of the parents of patients with CF and PCD. Methods...
Chapter
In the majority of patients with cerebral palsy, there is an involvement in hand functions, which vary according to the type of disease and extent of neurological involvement. Especially, deformities and postural disorders due to spasticity are important causes of deficiency. Problems associated with accompanying sensory and visual functions make t...
Article
Full-text available
Despite sore throat exists in the product characteristics of abobotulinum toxinA as one of the side effects, no available reports of sore throat after abobotulinum toxinA injection for adult upper limb spasticity could be found in the literature to guide physicians for the management. We report a case of poststroke spasticity who develop sore throa...
Article
Objectives: The aim of this review to evaluate the clinical aspects and effectiveness of suit therapy for patients with cerebral palsy (CP). Materials and methods: A literature search was performed in the PubMed, SCOPUS, Web of Science, and PEDro databases within the period from the establishment of the relevant database to July 2018. The articl...
Article
Objective To investigate the effect and superiority of fluoroscopy-guided intraarticular shoulder injection (IAI), suprascapular nerve block (SSNB), and combination treatment in hemiplegic shoulder pain (HSP). Design We included 30 patients diagnosed with HSP. Patients were divided into three groups: IAI, SSNB, and combination treatment. Patients...
Article
Full-text available
Objectives:The aims of this review to evaluate the clinical aspects and effectiveness of suit therapy for cerebral palsy. Patients and Methods:A literature search was performed in the PUBMED, SCOPUS, Web of Science and PEDro databases within the period from the establishment of the database through July 2018. The articles were categorized according...
Article
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Background Advances in surgical techniques, implant technology, radiotherapy, and chemotherapy have increased the recovery chances of patients with bone sarcomas. Accordingly, patients’ expectations on life quality have also increased, highlighting the importance of objective evaluation of the functional results of reconstruction. Methods Thirteen...
Article
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Purpose: To evaluate the effects of vest type dynamic elastomeric fabric orthosis on posture and balance during sitting and gross manual dexterity and to compare the efficacy of daily wearing time of 2 h versus 6 h. Method: Twenty-four children with cerebral palsy (CP) aged 3–9 years with GMFCS levels III and IV were randomised to either of three g...
Article
Introduction/Background The objective of this study is to investigate the effect of postural exercises addition to pulmonary rehabilitation in children with cystic fibrosis (CF) on pain, exercise tolerance, respiratory function, quality of life, balance and spinal deformities. Material and method Patients diagnosed with CF between the ages of 6 an...
Article
Full-text available
Introduction/Background Cystic fibrosis (CF) affects the musculoskeletal system via a multifactorial pathway that includes vitamin D deficiency and involvement of respiratory muscles such as intercostals due to recurrent upper and lower respiratory tract infections. Eventual result is the deterioration of musculoskeletal health and posture in CF pa...
Article
Full-text available
Introduction/Background The present study aimed: 1. To determine if children with SB demonstrate psychiatric disorders more than typically developing children 2. To assess if children with SB have more problems in executive functions and social responsiveness than TD children. 3. To investigate their relationship with neurologic level, ambulation s...
Article
Introduction/Background The aim of this study is to investigate the effects of kinesiology taping and different application techniques in the treatment of CMT in addition to therapeutic exercises. Material and method Thirty-three infants with congenital muscular torticollis were randomly assigned to three groups. Each was received stretching, stre...
Article
Background and aims The aim of this study was to investigate if the use of a vest type dynamic elastomeric fabric orthosis (DEFO) will lead to improvement in sitting balance, hip lateralization and gross manual dexterity. Methods Twenty-four children with CP between the ages of 3–7 with impaired trunk control were allocated to either of three grou...
Article
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Objectives: This study aims to evaluate pain in children with cerebral palsy (CP), to investigate its association with dependency level, verbal abilities, and the quality of life (QoL) of children and sociodemographic status, depression levels, and QoL of their caregivers. Patients and methods: Between February 2016 and April 2016, a total of 85...
Article
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Objective: The objective is to compare the fine and gross motor function of unaffected arms of children with obstetric brachial plexus palsy (OBBP) with typically developing children's dominant upper extremities. Methods: Fifty-three patients with OBBP and fifty-one typically developing children between the age of 4 and 13 were included in the s...
Article
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Objectives: This study aims to investigate whether the use of a lycra-based compression orthosis known as stabilizing input pressure orthosis (SPIO) vest improves trunk posture and hip lateralization in children with cerebral palsy (CP) and to compare the effects of two- and six-hours daily wear of the orthosis. Patients and methods: Between Dec...
Article
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Objectives: This study aims to investigate if function and mood involvement correlate in female patients who have a pre-diagnosis of carpal tunnel syndrome (CTS) and its correlation with physical examination and electrodiagnostic findings. Patients and methods: A total of 170 patients between the ages of 18-65 who applied to Physical Medicine an...
Article
Full-text available
Background Cystic fibrosis (CF) affects the musculoskeletal system via a multifactorial pathway that includes vitamin D deficiency and involvement of respiratory muscles such as intercostals due to recurrent upper and lower respiratory tract infections. Eventual result is the deterioration of musculoskeletal health and posture in CF patients. Postu...
Article
Full-text available
Background: The pediatric Gait, Arms, Leg, and Spine (pGALS) is a practical questionnaire for musculoskeletal (MSK) system evaluation in school-age children. Objective: The aim of this study was to evaluate the acceptability/practicality of pGALS Turkish translation in Turkey (cross-sectional study). Methods: The Turkish translation of pGALS w...
Article
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Objectives: This study aims to demonstrate the relationship between obesity and musculoskeletal system examination findings and functionality among 5-16 years old population-based sample. Patients and methods: This is a cross-sectional field study. Sample of this study was selected from 4,246 participants of a study, which assessed the prevalenc...
Article
Purpose: To investigate the validity and reliability of the Duruöz Hand Index (DHI) in patients with unilateral cerebral palsy (CP). Methods: Assessments of patients (n = 23) were performed using the Modified Ashworth Scale (MAS), the Manual Ability Classification System (MACS), the grip and pinch strength tests, and DHI. Following the data coll...
Article
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The respiratory secretions of patients with cystic fibrosis (CF) cause frequent pulmonary infections by thickening. These recurrent infections lead to lung damage and other pulmonary diseases. Pulmonary rehabilitation is descriptive in the management of CF and has an important role to clear the airways, to relieve shortness of breath and to increas...
Article
Full-text available
Objective: To investigate the effects of kinesiology taping and different types of application techniques of kinesiology taping in addition to therapeutic exercises in the treatment of congenital muscular torticollis. Design: Prospective, single blind, randomized controlled trial. Setting: An outpatient rehabilitation clinic in a tertiary univ...
Article
Background: The Pediatric Outcomes Data Collection Instrument (PODCI) has been created to evaluate functional status, to assess therapeutic needs and changes after treatment in 2 to 18 years old children and adolescents who have orthopedic problems. The PODCI has three forms; parent form for children, parent and self report forms for adolescents....