Evgeny Taratukhin

Evgeny Taratukhin
Pirogov Russian National Research Medical University | RNRMU · UNESCO Network Chair in Bioethics and Medical Law

MD, PhD, M.A., M.Psych

About

69
Publications
1,898
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
79
Citations
Citations since 2016
26 Research Items
76 Citations
201620172018201920202021202205101520
201620172018201920202021202205101520
201620172018201920202021202205101520
201620172018201920202021202205101520
Additional affiliations
November 2018 - May 2019
Pirogov Russian National Research Medical University
Position
  • Acting Head
May 2015 - present
Pirogov Russian National Research Medical University
Position
  • Professor (Associate)
April 2010 - May 2015
Pirogov Russian National Research Medical University
Position
  • Professor (Assistant)
Education
September 2014 - June 2016
September 2012 - June 2014
Ruhr-Universität Bochum
Field of study
  • Russian culture
September 2012 - June 2014
Russian State University for the Humanities
Field of study
  • cultural studies

Publications

Publications (69)
Article
Ethical norms are traditionally inseparable from medical work as such and are an unconditional part of the general idea of medicine and doctorhood. However, the structure of medical ethics is ambiguous and complex. It includes the ways in which ethically loaded decisions are made, the categories of ethically loaded decisions themselves and the good...
Article
In practice, a doctor constantly deals with difficult ethical situations, which requires optimal decisions. From weighing risks and benefits of an intervention to the need to change patient values in order to achieve prevention goals and increase compliance, questions of good and bad in a given situation are inevitable. At the same time, the deonto...
Article
When communicating with a patient, a doctor is within a certain cultural practice (science-based medicine and state health care system), falling outside the limits of which is not legal. However, a broader understanding of medicine as a cultural phenomenon with a focus on health also requires a more varied perspective on patient care. The patient’s...
Article
Full-text available
The concepts of spirituality and religiosity are studied in the context of cardiac disease and prevention. In psychology, psychosomatics, psychocardiology, spirituality is studied as a feature of human experience, attributed to certain transcendental ideas. Religiosity is a part of a person's self-identification, influencing his experience of inter...
Article
Full-text available
The article discusses ways to improve medication adherence using electronic devices. Applications for medication monitoring, currently available in the Russianlanguage Internet segment for Android OS devices in the Google Play Store is analyzed. For analysis, the main functional characteristics, determined by representative reviews of applications,...
Article
Full-text available
The health care system is a state institution that implements the constitutional right of citizens to health and medical care. It is part of the legal framework, and in case of unfavorable outcomes or the consequences of the medical process, law enforcement and judicial authorities may be involved. Sudden and rapid onset death is difficult categori...
Article
The article reveals the features of working with the patient as a social and psychological subject, who, in addition to somatic pathology, has an experience of the disease situation. Psychosocial risk factors for cardiovascular (and more generally non-infectious) pathology, as well as social well-being as a component of positive health, are conside...
Article
Full-text available
The article suggests the reasons for the delayed help-seeking in patients with acute coronary syndrome in terms of individualization of work. For analysis, the approach of narrative medicine was used, that is, a way to conceptualize medical situations using the methods of the humanities, or rather, to understand the disease as an event in the patie...
Article
Full-text available
The article shows biosocial relationships as elements of pathological changes of cardiovascular pathology — first at the functional, then at the morphological level. The ability to interact with the semantic, symbolic reality is the competence of a doctor, which allows helping people at the level of a person’s social identity. It is shown that in a...
Article
Full-text available
The review presents recent studies demonstrating somatic shifts in psychological processes regarded as the risk factors for myocardial infarction: depression, stress, anxiety. Based upon a metaphorical term “a perfect storm”, inflammatory, immunological, neuro-humoral predisposing factors are presented, important for myocardial infarction developme...
Article
The article is focused on the problem of evidence-based and individual approach relations in patient management, especially if a patient is on the periphery of statistical ranges. Recent literary data analyzed, on the opportunities for management individualization. Clinical case is provided of young female patient with spontaneous dissections of co...
Article
Full-text available
Aim. To assess the specifics of psychoemotional state of adult patients with non ST elevation acute coronary syndrome (NSTEACS) in 6 months post hospitalization. Material and methods. Totally, 101 patient included, with non-obstructive lesion of coronary flow. Groups were formed by gender: group 1 — 51 females, group 2 — 50 males. Mean age: women 5...
Article
Full-text available
The review is focused on the recent translational studies linking biological processes with the three common psychological states — risk factors for myocardial infarction. Subclinical inflammation, shifts of cortisol and other hormones levels are reviewed, and epidemiological data provided. In general, the data makes it to conclude that further stu...
Article
Aim. To investigate on psychological parameters of spiritiality and religiousness as events taking place during psychosocial rehabilitation of post myocardial infarction (MI) patients. Material and methods. Into the study, 103 patients (45 females) included, after an event of MI (≥3 days, during admittance). Mean age Me (Q1;Q3) =64,0 (56,0;77,5) y....
Article
The issue of non-communcable diseases risk factors is one of the main in global targets of healthcare. However the key point in this direction is still a patient-clinician communication that demands high level of understanding and empathy. A useful tool for clinical work might be person-centered interview. Aim. To evaluate epistemological role of p...
Article
Full-text available
Aim. Life quality is an integral parameter of medical care efficacy. In incomplete revascularization after myocardial infarction the quality of life might change in relevance with the severity of residual lesion. The study is done with an aim to reveal the specifics of patients life quality in such clinical situation. Material and methods. The inve...
Article
Full-text available
The literary analysis is presented to underline the importance and controversy of the meaning of patient-centered medicine, which attracts more and more researchers and practitioners. The origins of this concept are reviewed, its further directions as a novel generalized physician approach to a human with opportunity to launch positive dynamics on...
Article
Full-text available
Medicine of 21st Century has absorbed a broadest knowledge of biochemistry, genetics, pathology, pharmacology, which make to do wonders. More and more common is definition of medicine as personalized or patient-centred. However exact meanings of such “centredness” are still vague. This article is an attempt for modern reading of a classical text by...
Article
The study is one of the priority points of the Russian Scientific Medical Society of Internal Medicine, initiated due to known high average level of LDL cholesterol in Russian population and necessity for its optimized control by better access to treatment. Aim: To conduct comparative analysis of efficacy and safety of the rosuvastatin compound a...
Article
Full-text available
The case provided, about post-tachicardic cardiomyopathy that mimiced an acute coronary syndrome at admittance of patient. Regardless old age of the patient, after normal rhythm return there was successful cardiac function normalization, with normal clinical, electro-and echocardiographic parameters.
Article
Full-text available
Qualitative research is an aristocracy among research methods. Being capable to reach the understanding of events so deep and individual that unattainable for quantification, it requires the same level of capacities from an investigator. In cardiology, biomedical in her origins, novel patient-centered paradigm demands new understanding of the relev...
Article
Full-text available
The article focuses on new data on trimetazidine MB cytoprotection studies. The data provided on novel mechanisms of its effect including systemic action not related to myocardium. The results of epidemiological studies and meta-analysis are provided that confirm safety and efficacy of the medication in ischemic heart disease and chronic heart fail...
Article
Full-text available
The article focuses on the form of ethical controversy of the new drugs studies on humans. The issue is at its most importance in early phases of clinical trials that resemble an experiment, therefore requiring specific regulation. Has the difficulties been resolved, that are related to ethical aspects of human participants in new drugs investigati...
Article
Full-text available
The article takes into consideration a novel integrated approach that combines cultural and psychological parts of human being with biological signs of the disease and health. The historical roots from GL Engel are sketched, and some thoughts provided on evaluation and scientific significance of the approach in research and clinical practice.
Article
Full-text available
The article is focused on recent (last two years) data from the trials of alphaadrenoblocker urapidil as a drug of choice for severe refractory hypertension, for controlled hypotension, and for outpatient care as part of combination therapy.
Article
Full-text available
The article focuses on the review of recent data on Nebivolol as hypotensive and cardioprotecting medication. The accent is set upon the specific properties of nebivolol, partly, its influence on nitric oxide metabolism. The new information is provided on the study of pleiotropic effects of the drug.
Article
Full-text available
The review takes into consideration the novel data on heart failure treatment: application of mineralocorticoid antagonists. The pathogenetic points are highlighted that are proved by clinical trials, as epidemiological concerns. Further opportunites are sketched for this special kind of treatment by the growth of receptor interaction selectiveness...
Article
Full-text available
The article is on some contemporary data about genetic specifics of patients with sleep apnea syndrome. The data discussed is concerned on either adult and newborn subjects with the syndrome.
Article
Full-text available
The article takes into account the opportunity of the positive health, that is possible instead of the fight against diseases. As a main part of such interdisciplinary approach the personality is evaluated. To summon up the knowledge from biochemical to cultural bodies of human existence might turn medical science from the negation of a somatic dis...
Article
Full-text available
The article is about contemporary views on thrombolytic drugs usage. Although there is a great improvement in endovascular treatments, systemic thrombolysis is still one of the most important approaches to MI with ST elevation. The data of a few studies of thrombolytics with percutaneous intervention is provided, as with it or instead of it. Also t...
Article
Full-text available
The article takes into consideration a novel integrated approach that combines cultural and psychological parts of human being with biological signs of the disease and health. The historical roots from GL Engel are sketched, and some thoughts provided on evaluation and scientific significance of the approach in research and clinical practice.
Article
The article is focused on recent (last two years) data from the trials of alphaadrenoblocker urapidil as a drug of choice for severe refractory hypertension, for controlled hypotension, and for outpatient care as part of combination therapy.
Article
The article focuses on the form of ethical controversy of the new drugs studies on humans. The issue is at its most importance in early phases of clinical trials that resemble an experiment, therefore requiring specific regulation. Has the difficulties been resolved, that are related to ethical aspects of human participants in new drugs investigati...
Article
The article focuses on the review of recent data on Nebivolol as hypotensive and cardioprotecting medication. The accent is set upon the specific properties of nebivolol, partly, its influence on nitric oxide metabolism. The new information is provided on the study of pleiotropic effects of the drug.
Article
The article focuses on new data on trimetazidine MB cytoprotection studies. The data provided on novel mechanisms of its effect including systemic action not related to myocardium. The results of epidemiological studies and meta-analysis are provided that confirm safety and efficacy of the medication in ischemic heart disease and chronic heart fail...
Article
Full-text available
The paper is focused on additional, or off-target, effects of angiotensin-converting enzyme inhibitors (ACEI), zofenopril in particular. This is a new area in the pharmacological research, which is also relevant to antihypertensive agents. The authors present the data on potential interaction between ACEI and acetylsalicylic acid, as well as the re...
Article
Full-text available
The paper focuses on the problems in the treatment of patients with resistant arterial hypertension. The relevant recommendations from the European guidelines are presented. Angiotensin receptor antagonists are considered as a group of antihypertensive agents with additional benefits and good tolerability. The evidence on antihypertensive combinati...
Article
Full-text available
The paper is focused on the importance of Viktor A. Lusov, as well as the department he had been heading for many years, for the Russian cardiology. The biographical information and the data on Professor Lusov’s students and colleagues are presented. The authors emphasise the important role of the clinical school maintained by Viktor A. Lusov — a t...
Article
Full-text available
Aim. To assess the association between the changes in heart rate variability (HRV) and hemostatic parameters in patients with coronary heart disease (CHD) and chronic heart failure (CHF) as its complication. Material and methods. In total, 65 patients were examined at the O. M. Filatov City Clinical Hospital No. 15. The main group included 51 patie...
Article
Full-text available
The paper focuses on the important issue of cardio-cerebral interactions, cardiac comorbidities, and the need for complex therapeutic approaches. While stroke is traditionally regarded as a neurologic problem, cardiologists play an important role in its prevention, via modification of multiple risk factors. One of the key preventive measures is art...
Article
Full-text available
The paper presents the modern evidence on pharmacological treatment of patients with obesity and comorbidities, who try to modify their lifestyle, but are unsuccessful due to metabolic disturbances. The main and recently discovered additional effects of orlistat are discussed.
Article
Full-text available
The paper focuses on cytoprotective and additional effects of mildronate. The emphasis is on the latest original research evidence on mildronate effects in the settings of cardiovascular and cerebral ischemia. The authors also describe the latest laboratory data on the new therapeutic potential of mildronate.
Article
Full-text available
The paper discusses the importance of high treatment compliance in the case of long-term or life-long therapy. This problem can be resolved by the use of combination pharmacological treatment, such as the combination of a calcium channel blocker and an ACE inhibitor. Apart from the higher treatment compliance, this combination provides additional m...
Article
Full-text available
This literature review focuses on the angiotensin II receptor antagonists as one of the new and promising classes of antihypertensive medications. Apart from their antihypertensive activity, these agents possess a number of other beneficial effects. The results of multiple studies, including large multi-centre clinical trials, are presented for olm...
Article
Full-text available
The paper focuses on the problem of intravascular thrombosis and the methods of its treatment. The data on haemostasis pathophysiology, which underlie the occurrence of acute ischemic events in humans, are presented, together with the data on the action mechanisms of fibrinolytic medications. The focus is on tenecteplase, as a modified agent which...
Article
Full-text available
The paper emphases the need for dual antihypertensive therapy and describes its benefits, such as synergetic hypotensive action and other beneficial effects. One of the pathogenetically justified variants of combination therapy – a third-generation dihydropyridine calcium channel antagonist and an angiotensin-converting enzyme inhibitor – is discus...
Article
Full-text available
The paper describes the key aspects of arterial hypertension pathogenesis and the relevant therapeutic strategies. The authors discuss the role of increased peripheral vascular resistance and hypervolemia as factors which can be targeted by calcium channel blockers. The new evidence on this medication class, including the third-generation calcium a...
Article
Full-text available
The paper is focussed on the role of increased sympathetic activation in the pathogenesis of arterial hypertension (AH), its exacerbations (hypertensive crises), and complications. One of the effective methods of interrupting pathogenetic “vicious circles” in AH is the blockage of peripheral alpha-adrenoreceptors. One of the medications of choice f...
Article
Full-text available
The paper is focussed on the therapeutic choice of angiotensin receptor antagonists (ARA). The author presents the data on the comparison between different sartansand their benefits which are not explained by the blood pressure reduction. The findings from large multi-centre studies (EUTOPIA, DOHSAM, and OLIVUS-Ex) are also discussed. The evidence...
Article
Full-text available
The paper addresses the role of calcium channel blockers (CCB) in the treatment of patients with arterial hypertension and concomitant pathology. The authors present the findings of the recent studies on CCB effects on renal function, bronchial function, and systemic inflammation. This additional information on comorbidities is essential for the do...
Article
Full-text available
This review presents the modern evidence on the association between sleep apnoea syndrome and cardiovascular disease. Among other aspects, the recently discovered mechanisms linking sleep apnoea and the development of atherosclerosis, coronary heart disease, and cardiac arrhythmias, are discussed. The authors focus on the sleep apnoea syndrome impa...
Article
Full-text available
The paper discusses key aspects of the chronic heart failure (CHF) pathogenesis, which justify the use of ß-adrenoblockers (ß-AB) in the treatment of CHF. The authors present the clinical and experimental evidence confirming the effectiveness of these agents in CHF patients. Dose titration and the use of ß-AB in various clinical groups are also dis...
Article
Full-text available
The paper considers arterial hypertension and coronary heart disease as pathologies which share multiple pathogenetic mechanisms. The role of angiotensin Il receptor antagonists (ARA) in the effective treatment of these diseases and in prevention of their complications is discussed. The modern views on ARA and their indications are presented.
Article
Full-text available
The review presents the modern evidence on new properties of enalapril, which widens our perception of therapeutic effects of this medication.
Article
Full-text available
Heart rate variability (HRV) is a new method of non-invasive assessment of functional status, various levels of regulatory systems, and adaptation to internal and external factors. This review describes the development of HRV analysis, its physiological basis, some methodological aspects, and clinical potential.
Article
Full-text available
The paper is focused on the role of polyunsaturated fatty acids (PUFA) in the prevention of atherosclerosis and its complications. The description of PUFA chemical structure, their position in the lipid sub-class of fatty acids, and their main dietary sources is presented. The data from numerous studies confirm the beneficial role of PUFA in the tr...
Article
Full-text available
This document is an updated and extended version of the clinical guidelines by the Expert Committee of the Society of Cardiology of the Russian Federation, the Schmidt-Kudryashov All-Russian Association of Thrombosis, Haemorrhage, and Vascular Pathology, and the Russian Flebologists’ Association. The previous version was approved in 2006, at the jo...
Article
The activity of sympatho-adrenal system was investigated in 103 patients with post-infarction cardiosclerosis (mean age 59 years, mean body mass index – 27 kg/m2), with night sleep apnoea syndrome of varying severity. Morning blood pressure (BP) level, mean nighttime heart rate (HR), and urinary concentrations of vanilylamygdalic acid and total met...

Network

Cited By

Projects

Projects (3)
Archived project
Research on the impact of sleep apnea syndrome in coronary heart disease setting
Archived project
To analyze and provide updates on state of the art cardiovascular medications, including generics available in Russia