Evangelina Espósito

Evangelina Espósito
McGill University | McGill

MD. Ophthalmologist.

About

46
Publications
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194
Citations

Publications

Publications (46)
Article
Full-text available
Resumen Objetivos: Determinar los resultados refractivos poscirugía de catarata en pacientes mayores de 40 años y la influencia del largo axial y de la edad en ellos. Métodos: Estudio observacional, retrospectivo y analítico. Se estudiaron los pacientes mayores de 40 años sometidos a cirugía de catarata mediante facoemulsificación e implante de len...
Article
Full-text available
Purpose: To evaluate whether a mathematical tool that predicts severe retinopathy of prematurity (ROP) using clinical parameters at 6 weeks of life (ROPScore calculator smartphone application; PABEX Corporation) can be useful to predict severe ROP in a population of premature infants in Argentina. Methods: In this retrospective study, data from the...
Article
Full-text available
Objective: To assess current practices of intrav-itreal injections (IVI) and related complications among ophthalmologists in Argentina. Methods: In 2016, an anonymous web-based 39-question survey was designed using Google Forms tool and made accessible to 5,436 affiliated ophthalmologists to the Argentine Council of Ophthalmology currently practici...
Chapter
Choroidal neovascularization (CNV) is one of the most sight threatening complications of multiple eye diseases. While the diagnosis is primarily based on clinical and imaging findings, knowing the histopathology is fundamental to understanding the underlying causative pathophysiology. Due to the extensive differential diagnosis and potential etiolo...
Chapter
Choroidal neovascularization (CNV) is one of the most sight-threatening complications of multiple eye diseases. While the diagnosis is primarily based on clinical and imaging findings, knowing the histopathology is fundamental to understanding the underlying causative pathophysiology. Due to the extensive differential diagnosis and potential etiolo...
Article
Full-text available
INTRODUCCIÓN: Los drusen de papila son depósitos de material hialino calcificado a nivel de la cabeza del nervio óptico. Pueden ser difíciles de distinguir de la verdadera inflamación del nervio óptico y su identificación correcta es relevante debido a la morbilidad visual y sistémica que conlleva el diagnóstico de un verdadero edema de papila. OBJ...
Article
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INTRODUCCIÓN: En Argentina, la Sociedad Argentina de Oftalmología Infantil recomienda el examen ocular por parte de un especialista para todos los niños cuando nacen, a los seis meses, a los tres años y al inicio de la etapa escolar. Hasta el presente, no se han presentado en nuestros medios datos estadísticos de los hallazgos obtenidos OBJETIVO: D...
Article
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Resultados de los exámenes oftalmológicos en niños nacidos a término y sus antecedentes maternos Resumen INTRODUCCIÓN: En Argentina, la Sociedad Argentina de Oftalmología Infantil recomienda el examen ocular por parte de un especialista para todos los niños cuando nacen, a los seis meses, a los tres años y al inicio de la etapa escolar. Hasta el pr...
Article
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Objective: The purpose of our work was to study and compare the cornea and tear film of people and sheep inhabiting in a region of Argentinean Patagonia (PATG), and in a geographically and climatically different region in the Argentinean Pampa (CAPT). Methods: Using cross sectional study, corneal examinations were performed in people and Merino she...
Article
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Purpose Granuloma annulare (GA) is a rare clinical entity that does not classically arise from the peri-orbital area in adults. The purpose of this case report is to present a 69-year-old female with GA of the orbit. As well, the pathological and immunohistochemical features of these tumors will be discussed. Observations One case of GA of the orb...
Article
Objective: To develop a methodology to correlate optical coherence tomography (OCT) images and histopathological sections from the same eye. Part 1: To determine the best fixative for optimal OCT and histopathological analysis in post-mortem eyes. Part 2: A protocol is proposed to correlate histopathological features and OCT scans from the same po...
Article
Purpose/aim: Posterior capsular opacification (PCO) is the leading complication following cataract surgery. However, PCO grading methods vary between studies and rely on subjective scoring methods, hence they are prone to error. Therefore, software that reduces subjectivity and enhances reproducibility is needed. The aim of the study was to evaluat...
Article
Metastatic tumours to the orbit account for only a small proportions of orbital mass lesions and typically come from breast, prostate, lungs or metastatic melanomas. Identifying the source of the primary tumour may represent a challenge, as they are sometimes undiagnosed or the malignancies may sometimes have a different microscopic morphology. In...
Article
Full-text available
Purpose: To evaluate the results of Ahmed valve implantation in refractory glaucoma patients. Patients, Material and Methods: 14 eyes in 13 patients with refractory glaucoma to medical treatment, which underwent an implan- tation of an Ahmed valve between August 2007 and April 2015, with a minimum follow up of 24 months were retrospectively reviewe...
Chapter
Full-text available
Pterygium is an abnormal overgrowth of epithelial and fibrovas- cular tissue of the bulbar conjunctiva onto the corneoscleral limbus that may progress invading the superficial corneal layers. Usually, it develops horizontally on the nasal area of the interpalpebral fissure, but it may also affect the temporal side, and rarely both areas in a same e...
Article
Programmed cell death-1/ligand (PD-1/PD-L1) interaction negatively regulates T cell activity. PD-L1 expression in tumor cells, antigen-presenting cells, and lymphocytes of the tumor microenvironment is associated with response to treatment with PD-1/PD-L1 inhibitors, but there is still debate on the cutoff value that correlates with responders. In...
Article
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Purpose: Superior limbic keratoconjunctivitis (SLK) is a chronic and recurrent condition of unknown etiology. It is often managed conservatively, but there is a high rate of success with surgical management for severe or recalcitrant cases. The purpose of this article is to describe and analyze clinicopathological features of patients with SLK who...
Chapter
The choroid provides the main blood supply to the eye and plays a key role in eye physiology. Different entities can compromise its structure and function, having a striking impact on vision. Knowing the histology of the normal eye is fundamental for the correct understanding of the pathologic processes. This chapter is therefore organized into pat...
Article
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Background: Retinal tears complicating the course of a posterior vitreous detachment (PVD) may be unique or multiple, and when multiple they may occur simultaneously or subsequently at different moments in the evolution of a PVD. The purpose of our study was to analyze the prevalence of subsequent retinal tears (SRT) in patients with a PVD, and to...
Article
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Background Light exposure and more specifically the spectrum of blue light contribute to the oxidative stress in Age-related macular degeneration (AMD). The purpose of the study was to establish whether blue light filtering could modify proangiogenic signaling produced by retinal pigmented epithelial (RPE) cells under different conditions simulatin...
Cover Page
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Cover: The cover image, by Maria Fernanda Suarez et al., is based on the Article, Phospholipidomic Studies in Human Cornea From Climatic Droplet Keratopathy, DOI: 10.1002/jcb.26045.
Article
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Objetivo: Evaluar los resultados del implante de válvula de Ahmed en pacientes con diferentes tipos de glaucoma refractario. Pacientes, material y métodos: 14 ojos de 13 pacientes mayores de 18 años con glaucoma refractario al tratamiento médico máximo y operados mediante la implantación de válvula de Ahmed (Modelo AGV-FP7) entre Agosto de 2007 y...
Article
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Introducción: Dentro de las vasculopatías retinianas, las oclusiones venosas de la retina (OVR) representan la segunda causa más frecuente de pérdida de visión luego de la retinopatía diabética. Se han descripto dos tipos diferentes de OVR: la oclusión de vena central de la retina (OVCR), y la oclusión de rama venosa retinal (ORVR). De acuerdo al c...
Article
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Climatic droplet keratopathy (CDK) is an acquired degenerative disease predominantly affecting males over 40 years old. It results in progressive corneal opacities usually affecting both eyes. CDK is multifactorial and its etiology remains unknown. Our recent findings are consistent with CDK pathology being driven by environmental factors with oxid...
Article
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Purpose: To investigate the effect of nicotinamide on the secretion of pro-an giogenic and pro-inflammatory cytokines in uveal melanoma cell lines. Methods: Two human uveal melanoma cell lines (92.1 and OCM-1) were treated with nicotinamide (10 mmol/L) or control media for 48 hours in culture. The su perna tant from each culture was used in sandwi...
Article
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Objetivo: El objetivo de este trabajo fue determinar las preferencias de los cirujanos argentinos en el manejo perioperatorio de la cirugía de cataratas para la prevención de endoftalmitis posquirúrgica. Métodos: El Consejo Argentino de Oftalmología realizó por internet una encuesta a sus miembros sobre los factores de riesgo para endoftalmitis en...
Article
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Background: Retinoblastoma (RB) is the most common primary intraocular malignancy. Current therapies are associated with high morbidity in the short- and long-term. Human epidermal growth factor receptor 2 (HER2) is a transmembrane protein detected in 15-30% of breast cancers, but it has also been described in other malignancies. Recently, it has...
Article
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Background: Acute-onset postoperative endophthalmitis after cataract surgery remains a rare but important cause of visual loss. There is no global consensus regarding the optimal strategies for prophylaxis of endophthalmitis and practices vary substantially around the world, especially with respect to the use of intracameral antibiotics. The Europ...
Article
Conjunctival melanoma is the second most common conjunctival malignancy. Its differential diagnosis with other conjunctival melanocytic neoplasms is inherently difficult. The presence of epithelial cysts is a useful feature in conjunctival tumors and favors a benign lesion. Herein 2 cases of conjunctival melanoma with cysts are presented. To the be...
Article
As metabolism is controlled by the input of genes and the environment, metabolic disorders result from some disturbance in the interaction between genes and environmental factors. Many metabolic disorders consist in congenital enzyme deficiencies, also known as “inborn errors of metabolism”, that may be disabling or cause severe illness and death,...
Article
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The eye ans skin may offer critical clues to the diagnosis of a varied spectrum of metabolic diseases from endocrine origin and their different stages of severity, such as diabetes mellitus and Graves disease. On the other hand, such entities may compromise the eye and the visual function severely, and to be aware of these possible associations is...
Article
Full-text available
Objective: The purpose of our work was to study and compare the cornea and tear film of people and sheep inhabiting in a region of Argentinean Patagonia (PATG), and in a geographically and climatically different region in the Argentinean Pampa (CAPT). Methods: Using cross sectional study, corneal examinations were performed in people and Merino she...
Article
Full-text available
Climatic droplet keratopathy (CDK) is a degenerative corneal disease of unknown etiology. We described CDK for the first time in Latin America in the Argentinean Patagonia (El Cuy). A deeper knowledge of CDK pathogenic mechanisms will provide new therapeutic strategies. For that reason we investigated the prevalence of CDK in El Cuy and its existen...
Article
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Background: Conjunctival amyloidosis is a very rare condition, generally unilateral, and presents mostly as an isolated condition without systemic compromise. Our purpose is to present a new case of systemic amyloidosis with a bilateral conjunctival involvement. Case presentation: A 66-years-old caucasian female complaining of conjunctival hemor...
Poster
Full-text available
Abstract Purpose: Climatic droplet keratopathy (CDK) is a human degenerative corneal disease characterized by protein aggregation under the epithelium and caused by unfavorable environmental conditions (chronic exposure to ultraviolet radiation (UVR), constant erosions of the cornea) which induce oxidative stress. In an attempt to develop an experi...
Article
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To present a case of a complicated posterior melanocytoma that was successfully treated with intravitreal bevacizumab. A 50-year-old Caucasian man was referred with sudden-onset metamorphopsia and decreased vision in his right eye over the course of the last 2 months. His best-corrected visual acuity was 20/80 and poorer than Jaeger 14 in the right...
Article
We report a case of Alternaria keratitis and hypopyon following clear-corneal cataract surgery. A 66-year-old woman presented with a painful red left eye several months after uneventful self-sealing clear-corneal phacoemulsification that was unresponsive to prolonged treatment with topical/oral quinolones and topical corticosteroids. A full-thickne...
Chapter
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The cornea plays important roles in the eye since it not only maintains the ocular pressure and protects against different aggressions and forces but constitutes the primary lens in many animals' eyes as well. In order to fulfill these extremely crucial functions, the cornea requires sophisticated structures called the epithelium, Bowman's membrane...
Article
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Although frequently underdiagnosed, squamous cell carcinoma is the most commonly observed malignancy of the conjunctiva. Multiple different treatments have been proposed to date. The purpose of this paper is to report our experience in the treatment of In situ carcinoma of the conjunctiva by surgical excision associated with cryotherapy. Four eyes...
Article
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ARCHIVOS DE ALERGIA E INMUNOLOGÍA CLÍNICA 2013;44(3):90-96 ABSTRACT Purpose. To investigate Single Nucleotide Polymorphism (SNP) at-308 position (G/A) of TNF-α gen and involving of TNF-α and MCP-1 cytokines in Climatic Droplet Keratopathy (CDK) patients and healthy controls. Materials and methods. Fifteen patients with CDK and fi fteen healthy con...

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Projects (3)
Project
To perform immunologic, metabolomic, proteomic, lipidomic and RNA sequencing studies in human diseases which involve epithelium and connective tissue abnormalities, in order to get inside into their etiopathogenesis.