Eva Aguirre

• National Autonomous University of Mexico

Mexico is considered one of the countries with the greatest diversity of the Salvia genus. A significant percentage of its species are known for their use in traditional medicine, highlighting their use as an analgesic. The objective of this work was to determine the chemical composition of the methanolic extracts of S. cinnabarina, S. lavanduloide...

The genus Salvia (Lamiaceae) is widely distributed in Mexico with approximately 300 species. Aerial parts, leaves, and branches of sages are prepared as infusions or decoctions in traditional Mexican medicine to treat conditions such as dysentery, diarrhea, gastritis, stomach-ache, headache, sore throat, cough, bronchitis, fever, diabetes, epilepsy...

Nepetoideae is the most diverse subfamily of Lamiaceae, and some species are well known for their culinary and medicinal uses. In recent years, there has been growing interest in the therapeutic properties of the species of this group regarding inflammatory illnesses. This study aims to collect information on traditional uses through ethnobotanical...

Salvia semiatrata Zucc. (Lamiaceae) is endemic to Oaxaca, Mexico, and is known for its analgesic properties. Terpenoids and phenolic compounds with antinociceptive potential have been characterised from this species. The aim of this research was to determine the variation in terpenoids and flavonoids in ethyl acetate extracts of S. semiatrata colle...

Ethnopharmacology relevance: Petiveria alliacea L., commonly known as macura and gully root, is an important medicinal plant used in the Caribbean and Central America to treat ailments associated to the central nervous system, including poor memory. Aim of the study: To assess the effects of the P. alliacea leaves methanol fraction (PMF) on a sc...

Salvia amarissima Ortega is an endemic species of Mexico used in folk medicine to alleviate pain and as a nervous tranquilizer. The S. amarissima extract and one of its abundant metabolites, identified and isolated through chromatographic techniques, were investigated to obtain scientific evidence of its potential effects to relieve nociplastic pai...

Salvia is the most diverse genus within the mint family (Lamiaceae), many of its species are well-known due to their medicinal and culinary uses. Most of the ethnopharmacological and phytochemical studies on Salvia are centred on species from the European and Asian clades. However, studies about the most diverse clade, the Neotropical sages (Salvia...

Ethnopharmacological relevance Petiveria alliacea L. is traditionally used as a folk medical herb in different regions of the world to treat different ailments including those related to the central nervous system. Previous studies have proved that extracts from P. alliacea show improvement in memory and learning process. Aim of the study To study...

Antecedentes: Salvia purpurea Cav., comúnmente conocida como “salvia moradita”, es una planta medicinal usada en Oaxaca, Veracruz y Chiapas por sus propiedades analgésica, antiinflamatoria y antidiarreica. Sin embargo, no existen evidencias científicas que soporten su potencial para el alivio del dolor. Hipótesis: Terpenos y compuestos fenólicos s...

The search for molecules that contribute to the relief of pain is a field of research in constant development. Lamiaceae is one of the most recognized families world-wide for its use in traditional medicine to treat diseases that include pain and inflammation. Mexico can be considered one of the most important centers of diversification, and due to...

Three derivatives of the scaffold, 1,3-bis(benzimidazol-2-yl)benzene 1–3, were synthesized and structurally characterized by single X-ray diffraction. Spectroscopic studies by fluorescence competitive displacement assays, UV–Vis, circular dichroism, and docking simulations revealed that the interaction of these derivatives with ds-DNA at pH= 7.4 is...

Context Salvia semiatrata Zucc. (Lamiaceae) is a species used as a tranquilizer and to relieve pain in folk medicine in Santiago Huauclilla, Oaxaca, Mexico. Objective To evaluate the antinociceptive and anxiolytic-like effects of S. semiatrata extracts and identify a bioactive metabolite. Materials and methods The extracts were obtained by macera...

p align="left"> Background : Salvia circinata is an endemic species of Mexico used in the folk medicine of Santiago Huauclilla, Oaxaca, mainly as remedy for gastrointestinal diseases. Hypothesis : If the extracts of Salvia circinata have secondary metabolites with antinociceptive activity, then the behavior of nociception in the model of “whriting”...

HPLC analysis of capsaicin and dihydrocapsaicine concentrations obtained from fruits of Capsicum annuum var. glabris-culum, collected from four localities in the state of Tamaulipas, Mex-ico, was investigated. Selection of localities for this study was carried out considering that 65% of the people living in them gather wild chilli pepper for eithe...

Flavonoids are compounds that are secondary metabolites, but which play an important role in the biological activities of plants. They can be responsible for the color of flowers and fruits and for the attraction of pollinators. They also participate in plant-microorganism symbiosis. These relationships can be used to naturally control weeds and in...

Context: Lippia species (Verbenaceae) are widely used in Latin America and Africa as folk medicine for their tranquilizing properties. Objective: To evaluate the anxiolytic-like effects and safety of Lippia graveolens Kunth. by exploring its aqueous and organic leaf extracts and identifying the responsible chemical constituents. Material and method...

INTRODUCTION: The inflorescences of Tilia americana var. mexicana are used as an infusion in Mexican traditional medicine due to their tranquilizing effects; however, pharmacological and phytochemical studies of the leaves are lacking. OBJECTIVE: In this research, the anxiolytic and sedative-like efficacy of the Tilia americana var. mexicana leave...

Tilia genus is commonly used around the world for its central nervous system properties; it is prepared as tea and used as tranquilizing, anticonvulsant, and analgesic. In this study, anticonvulsant activity of the Tilia americana var. mexicana inflorescences and leaves was investigated by evaluating organic and aqueous extracts (100, 300, and 600...

Tilia americana L. var. mexicana (Schltdl.) Hardin (Tiliaceae) (T. americana) is widely used by people for its therapeutic effects on the central nervous system. Although pharmacological effects of this plant species have been reported in experimental models of nociception and depressant activities associated to the presence of flavonoids, other Ti...

Annona genus contains plants used in folk medicine for the treatment of diabetes. In the present study, an aqueous extract prepared from Annona macroprophyllata (Annonaceae, also known as A. diversifolia) leaves was evaluated on both the activity of yeast α -glucosidase (an in vitro assay) and sucrose tolerance in Wistar rats. The results have show...

Species from the Ternstroemiaceae family are commonly used in Mexican traditional medicine prepared as infusion or decoction. In the present study, aqueous extracts obtained from the flowers, fruits, and seeds of Ternstroemia genera and fruits of two species of Cleyera genera were evaluated for flavonoid presence by planar chromatography using NP-P...

Around the world, Tilia species have been used in traditional medicine for their properties as tranquilizer. Furthermore, Mexican species of Tilia have been grouped as Tilia americana var. mexicana, but their specific content in flavonoids is poorly described. In this study, inflorescences of Mexican Tilia were collected in three different regions...

Tilia species are well known around the world for their properties in traditional medicine. Antinociceptive activity of hexane, methanol and aqueous extracts from Tilia americana var. mexicana inflorescences was evaluated in the pain-induced functional impairment model in rats (PIFIR). A preliminar 300 mg/kg dosage of aqueous extracts i.p., but not...

Tilia species have been used as anxiolytics for many years. In a previous study anxiolytic-like effects of a hexane extract of Tilia americana var. mexicana inflorescences were observed in experimental models in mice. To get additional insights into the neuroactive actions of this particular Tilia species, in this study we report a bioactivity guid...

The anxiolytic and sedative effects of Tilia americana L. var. mexicana (Schltdl.) Hardin inflorescence extracts and its acute toxicity were tested. Sodium pentobarbital (SP)-induced hypnosis potentiation (SPP), as well as ambulatory activity and anti-anxiety response in three different experimental models were evaluated with hexane and methanol ex...