Eva-Lotta Brakemeier

Eva-Lotta Brakemeier
University of Greifswald · Institute of Psychology

Prof. Dr.

About

192
Publications
68,924
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
2,923
Citations
Citations since 2016
107 Research Items
2086 Citations
20162017201820192020202120220100200300400
20162017201820192020202120220100200300400
20162017201820192020202120220100200300400
20162017201820192020202120220100200300400
Additional affiliations
December 2012 - present
Psychologische Hochschule Berlin
Position
  • Professor
August 2007 - November 2012
University of Freiburg
Position
  • Medical Professional
October 2006 - February 2007
New York State Psychiatric Institute
Position
  • PhD Student

Publications

Publications (192)
Article
In recent decades, randomized-controlled trials (RCTs) have established a broad evidence base of psychotherapy with moderate-to-large effects for various mental disorders. In addition to determining the efficacy of psychotherapy, studies examining its effectiveness under everyday conditions historically paved the way for developing a practice-orien...
Article
Objectives: Predictive processing approaches to belief updating in depression propose that depression is related to more negative and more precise priors. Also, belief updating is assumed be negatively biased in comparison to normative Bayesian updating. There is a lack of efficient methods to mathematically model belief updating in depression. M...
Article
Full-text available
Background Perceived loneliness and objective social network size are related but distinct factors, which negatively affect mental health and are prevalent in patients who have experienced childhood maltreatment (CM), for example, patients with persistent depressive disorder (PDD) and borderline personality disorder (BPD). This cross-diagnostic stu...
Article
Background Childhood trauma is a common and potent risk factor for developing major depressive disorder in adulthood, associated with earlier onset, more chronic or recurrent symptoms, and greater probability of having comorbidities. Some studies indicate that evidence-based pharmacotherapies and psychotherapies for adult depression might be less e...
Article
Background: The Cognitive Behavioral Analysis System of Psychotherapy (CBASP) is an empirically supported psychotherapeutic treatment developed specifically for persistent depressive disorder. However, given the high rates of nonresponse and relapse, there is a need for optimization. Studies suggest that outcomes can be improved by increasing the...
Article
Full-text available
Background: Although intrusions are the hallmark symptom of posttraumatic stress disorder, there is still limited knowledge about the processes that contribute to the development of intrusions. Here, we used the well-established trauma film paradigm (TFP) to investigate how expectations about the intensity and controllability of intrusions influenc...
Article
Full-text available
Background Depression is a serious disorder in childhood and adolescence. Affected children and adolescents show significant impairments in various aspects of life. Studies on the effectiveness or efficacy of psychotherapy in depressed children and adolescents are qualitatively very heterogeneous and reveal small effect sizes. There is thus a need...
Article
Suicidal ideation and behavior (SIB) are common in persistent depressive disorder (PDD) and may be related to interpersonal dysfunction. While SIB has been extensively analyzed in other high-risk disorders (e.g., borderline personality disorder, BPD), data on interpersonal risk factors and effects of specific psychotherapy on SIB in PDD are limited...
Article
Full-text available
Background With a lack of experimental designs that explore which therapeutic style is helpful for which patient, the aim of this study was to test the feasibility of experimentally varying the therapeutic style under realistic conditions and to investigate how this affects alliance ratings by clients and counselors. Methods We defined two manuali...
Article
Full-text available
Eine Leitlinie soll Fachpersonen, Betroffenen und der gesamten Bevölkerung evidenzbasierte Empfehlungen auf Basis des aktuellen wissenschaftlichen Erkenntnisstands zu Diagnostik- und Behandlungsmöglichkeiten geben. Der 3. Entwurf zur Nationalen Versorgungsleitlinie (NVL) Depression wird aktuell zur Diskussion gestellt. Gerade die Diskussionsvorlage...
Conference Paper
Full-text available
Depression is a large-scale and consequential problem in youth and young adults. Conversational agents (CAs) can contribute to addressing current barriers to seeking treatment, such as long waiting lists, and reduce the high dropout rates reported for other digital health interventions. However, existing CAs have not considered differences between...
Article
Dysfunctional expectations are a particularly important subset of cognitions that influence the development and maintenance of various mental disorders. This study aimed to develop and validate a scale to assess dysfunctional expectations in posttraumatic stress disorder (PTSD), the "Posttraumatic Expectations Scale" (PTES). In a cross-sectional st...
Article
Full-text available
Background To slow down the spread of COVID-19, the observance of basic hygiene measures, and physical distancing is recommended. Initial findings suggest that physical distancing in particular can prevent the spread of COVID-19. Objectives To investigate how information to prevent the spread of infectious diseases should be presented to increase...
Article
Importance: Major depressive disorder (MDD) affects approximately 10% of the population globally. Approximately 20% to 30% of patients with MDD do not sufficiently respond to standard treatment. Therefore, there is a need to develop more effective treatment strategies. Objective: To investigate whether the efficacy of cognitive behavioral therap...
Preprint
Full-text available
Introduction Breast cancer is the most common form of cancer in women. A considerable number of women with breast cancer who have been treated with chemotherapy, subsequently develop neurological symptoms such as concentration and memory difficulties (also known as ‘chemobrain’). Currently, there are no validated therapeutic approaches available to...
Article
Full-text available
Introduction A substantial number of patients diagnosed with COVID-19 experience long-term persistent symptoms. First evidence suggests that long-term symptoms develop largely independently of disease severity and include, among others, cognitive impairment. For these symptoms, there are currently no validated therapeutic approaches available. Cogn...
Article
Full-text available
The objectives of this study were to investigate the naturalistic effectiveness of routine inpatient treatment for patients with obsessive–compulsive disorder (OCD) and to identify predictors of treatment outcome. A routinely collected data set of 1,596 OCD inpatients (M = 33.9 years, SD = 11.7; 60.4% female) having received evidence-based psychoth...
Article
Full-text available
Understanding implementation-related factors and processes is key to ensuring that Internet-based interventions are embedded in practice and provide added value to the delivery of evidence-based care. The aim of this study was to evaluate the attitudes towards an Internet-based cognitive behavioural therapy (iCBT) intervention for the treatment of...
Article
Full-text available
Purpose: Depressive disorders in children and adolescents have an enormous impact on their general quality of life. There is a clear need to effectively treat depression in this age group. Effects of psychotherapy can be enhanced by involving caregivers. In our systematic review and meta-analysis, we examine for the first time the effects of careg...
Article
Full-text available
Practitioners and researchers alike assume that there is individual variability in the effects of treatments for mental disorders. However, for psychotherapy, up to now this assumption has never been empirically tested. Using a large database of randomized-controlled trials on psychotherapy of depression in adults (306 trials including a total of 5...
Article
Background A routinely collected dataset was analyzed (1) to determine the naturalistic effectiveness of inpatient psychotherapy for depression in routine psychotherapeutic care, and (2) to identify potential predictors of change. Methods In a sample of 22,681 inpatients with depression, pre-post and pre-follow-up effect sizes were computed for va...
Article
Full-text available
Background: Divergent outcomes of treatment for depression occur regularly, but often go undetected by clinical judgment alone. To date, no comprehensive studies are available on what the detection rate of divergent outcomes is in routine care. Method: We analyzed a large (N = 20,882) database of clinician-rated and patient-reported outcomes from...
Chapter
Ziel der interpersonellen Diskriminationsübung ist es, Patienten dafür zu sensibilisieren, dass ihr Verhalten Konsequenzen in anderen Personen bewirkt. Die Durchführung der interpersonellen Diskriminationsübung basiert auf einer therapeutischen Haltung, in der sich der Therapeut diszipliniert persönlich einbringt. Sie basiert zudem auf der Kenntnis...
Preprint
BACKGROUND The Cognitive Behavioral Analysis System of Psychotherapy (CBASP), developed specifically for the treatment of persistent depressive disorder (PDD), is an empirically supported treatment. However, given the high rates of non-response and relapse, there is need for optimization. Studies suggest that outcomes can be improved by increasing...
Chapter
Die Situationsanalyse ist eine strukturierte, mehrstufige, interpersonelle Problemlöse- bzw. Situation-Reaktion-Konsequenz-Technik. Mithilfe der Situationsanalyse sollen Patienten lernen, ihre Aufmerksamkeit auf konkrete, zeitlich klar umgrenzte interpersonelle Situationen zu fokussieren und dafür alternative, zum erwünschten Ziel führende Denk- un...
Article
Full-text available
The COVID-19 pandemic is one of the most serious health and economic crises of the 21st century. From a psychological point of view, the COVID-19 pandemic and its consequences can be conceptualized as a multidimensional and potentially toxic stressor for mental health in the general population. This selective literature review provides an overview...
Article
Full-text available
Background: There is an urgent need for effective follow-up treatments after acute electroconvulsive therapy (ECT) in depressed patients. Preliminary evidence suggests psychotherapeutic interventions to be a feasible and efficacious follow-up treatment. However, there is a need for research on the long-term usefulness of such psychotherapeutic offe...
Article
Full-text available
Background: A growing number of studies indicate that the Cognitive Behavioral Analysis System of Psychotherapy (CBASP) is effective in treating chronic depression. However, there is no systematic research into possible negative effects. Therefore, the objectives of the study were to investigate the rate of occurrence of negative effects of an inpa...
Article
Full-text available
Background Meta-analytic results indicate that posttraumatic stress disorder (PTSD) is associated with hypoactivation of the medial prefrontal cortex (mPFC), hyperactivation of the amygdala, and volume reductions of the hippocampus. Effective psychotherapeutic treatments were hypothesized to normalize these neural patterns via upregulation of prefr...
Article
Full-text available
Despite effective treatment approaches within the cognitive behavioral framework general treatment effects for chronic pain are rather small to very small. Translation from efficacy trials to naturalistic settings is questionable. There is an urgent need to improve the effectiveness of well-established treatments, such as cognitive-behavior therapy...
Preprint
Full-text available
We read the article “Clinimetric Criteria for Patient-Reported Outcome Measures” with great interest. Highlighting certain test characteristics for patient-reported outcome measures (PROMs) that seem to be neglected in the psychometric literature is a commendable endeavor. We share the authors' intention of supporting clinical practice by providing...
Article
Die Psychotherapie sollte in der Behandlung der Depression neben der akuten Symptomreduktion auch die Wahrscheinlichkeit eines erneuten Auftretens der Störung bzw. eines Rückfalls verringern. Der Patient soll lernen, erneuten Verschlechterungen eigenverantwortlich vorzubeugen und diese zu bewältigen. Im Beitrag werden bewährte und neuere Ansätze de...
Article
Background Loneliness is a distressing and prevalent symptom in patients with persistent depressive disorder (PDD) that is associated with depression severity, a history of childhood maltreatment and rejection sensitivity. As loneliness is no primary focus of psychotherapy to date and the Cognitive Behavioral Analysis System of Psychotherapy (CBASP...
Preprint
Objective: Although intrusions are the hallmark symptom of Posttraumatic Stress Disorder (PTSD), there is still limited knowledge about the processes that contribute to the development of intrusions. Here, we used the well-established trauma film paradigm (TFP) to investigate how expectations about the intensity and controllability of intrusions in...
Article
Background: Many depressed patients are treated in institutional settings. The number of studies focusing on psychotherapies for depressed patients in institutional settingsis limited, and only a few up-to-date meta-analyses have integrated the results of these studies. Methods: We conducted a meta-analysis of 32 randomized trials with 37 compariso...
Article
Full-text available
Im Zuge der Anfänge der Verhaltenstherapie (VT) und der “kognitiven Wende” wurde der aktiven Beziehungsgestaltung und damit verbundenen Faktoren zunächst nur zweitrangig Beachtung geschenkt, obwohl die Bedeutung der Beziehung zwischen Therapeut und Patient auch in der VT bereits relativ früh erkannt wurde. Seitdem hat sich die VT substanziell weite...
Article
Full-text available
The Cognitive Behavioral Analysis System of Psychotherapy (CBASP) was originally developed for outpatients with persistent depressive disorder (PDD). We adapted CBASP as inpatient treatment on a general acute psychiatric ward and evaluated its outcome and feasibility. Sixty PDD patients received a 12-week multidisciplinary CBASP program. Hamilton D...
Article
Full-text available
Posttraumatic stress disorder (PTSD) is characterized by intrusions, avoidance, and hyperarousal while patients of the dissociative subtype (PTSD-D) experience additional dissociative symptoms. A neurobiological model proposes hyper-inhibition of limbic structures mediated by prefrontal cortices to underlie dissociation in PTSD. Here, we tested whe...
Preprint
Dysfunctional expectations are a particularly important subset of cognitions that influence the development and maintenance of various mental disorders. This study aimed to develop and validate a scale to assess dysfunctional expectations in posttraumatic stress disorder (PTSD), the “Posttraumatic Expectations Scale” (PTES). In a cross-sectional st...
Article
Full-text available
Background: Comorbidities in mental disorders are often understood by assuming a common cause. The network theory of mental disorders offers an alternative to this assumption by understanding comorbidities as mutually reinforced problems. In this study, we used network analysis to examine bridge symptoms between anxiety and depression in a large sa...
Article
Full-text available
Introduction: The Cognitive Behavioral Analysis System of Psychotherapy (CBASP) was developed for the treatment of persistent depressive disorder (PDD), where comorbid personality disorders (PD) are common. In contrast to other PD, comorbid borderline personality disorder (BPD) is often regarded as an exclusion criterion for CBASP. In clinical sett...
Article
Full-text available
Objective: Little is known about the specific psychological features that differentiate persistent depressive disorder (PDD) and episodic depression (ED). Thus, the present study aimed to investigate differences in social cognition and interpersonal problems between these two forms of depression and healthy controls. In addition, we aimed to examin...
Preprint
Objective: In psychotherapy process research, there is a lack of experimental designs that specifically explore which therapeutic style is helpful for which patient. Thus, the aim of this study was to test the feasibility of experimentally varying the therapeutic style under realistic conditions and how this affects alliance. Method: We defined two...
Article
Zusammenfassung. Die COVID-19-Pandemie als multidimensionaler und potenziell toxischer Stressfaktor führt auch in Deutschland zu psychischen Problemen in der Allgemeinbevölkerung und wird voraussichtlich einen Anstieg der Inzidenz- und Prävalenzraten psychischer Störungen bedingen. In diesem Positionspapier erfolgt daher eine wissenschaftlich diffe...
Preprint
Full-text available
Background Psychotherapy is an evidence-based treatment for depression, but its average effect is modest. Thus, identifying subgroups that respond especially well to psychotherapy is an important goal. This would allow maximizing the efficacy of interventions. However, the extent of treatment effect heterogeneity (TEH) has not yet been systematical...
Preprint
BACKGROUND To slow down the spread of COVID-19, the observance of basic hygiene measures, and physical distancing is recommended. Initial findings suggest that physical distancing in particular can prevent the spread of COVID-19. Attitudes towards these measures are influenced by many factors and are likely to play an important role in their compli...
Article
Objective: The aims of this study were to determine the effectiveness of a routine clinical care treatment and to identify predictors of treatment outcome in PTSD inpatients. Methods: A routinely collected data set of 612 PTSD inpatients (M = 42.3 years [SD = 11.6], 75.7% female) having received trauma-focused psychotherapy was analyzed. Primary ou...
Article
Childhood maltreatment (CM) is a risk factor for numerous mental disorders. However, the specificity of CM types in mental disorders is still being discussed. The present study examined the prevalence of five CM types in patients with schizophrenia/schizoaffective disorder (SZ; n=107), bipolar disorder (BD; n=103), depression (MDD; n=604; with the...
Article
Background A routinely collected big data set was analyzed to determine the effectiveness of naturalistic inpatient treatment and to identify predictors of treatment outcome and discontinuation. Methods The sample included 878 patients with borderline personality disorder who received non-manualized dialectic behavioral therapy in a psychosomatic...
Article
Objective To examine attachment insecurity and low social support as potential mediators of the association between childhood maltreatment (CM) types and depression severity in patients with a lifetime history of major depressive disorders (MDD). Method Participants with an acute or remitted MDD (N = 580) completed questionnaires about CM (Childho...
Article
In light of ongoing demographic changes, it is essential to tailor psychotherapeutic approaches and interventions to the specific needs and characteristics of older adults. An interpersonal skills group (ISG) for older adults consisting of modified Cognitive Behavioral Analysis System of Psychotherapy (CBASP) elements (Situational Analysis, Kiesler...
Article
Full-text available
Freier Download: https://www.karger.com/Article/FullText/507820 Einleitung: Voraussetzung für die Approbation im Rahmen der neuen Psychotherapeutenausbildung ist u.a. das Bestehen einer anwendungsorientierten Parcoursprüfung. Da diese Prüfung von Lehrenden und Studierenden als Herausforderung angesehen wird, wurde eine Kurzform der Parcoursprüfung...
Article
Difficult situations in psychotherapy and how therapists deal with themObjectives: In theory and research, it is assumed that therapeutic competences are especially relevant in difficult situations. In the present study, we collected and categorized situations that psychotherapists subjectively evaluated as difficult. Additionally, we inspected the...
Article
Full-text available
Objective: While the efficacy of psychotherapy in the treatment of mental disorders is well examined, systematic research into negative effects of psychotherapy seems comparatively rare. Therefore, this review evaluates instruments for assessing negative effects of psychotherapy in order to create a consensus framework and make recommendations for...