
Eva Rodriguez HortelanoUniversity of the Basque Country | UPV/EHU · Biochemistry and Molecular Biology
Eva Rodriguez Hortelano
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Publications (4)
Fusion and fission drive all vesicular transport. Although topologically opposite, these reactions pass through the same hemi-fusion/fission intermediate, characterized by a 'stalk' in which only the outer membrane monolayers of the two compartments have merged to form a localized non-bilayer connection. Formation of the hemi-fission intermediate r...
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Coupling between membrane shape and composition plays an important role in dynamic life of cellular membranes. It becomes increasingly understood that intrinsic curvature preferences of membrane components, proteins and lipids, provides one of the driving forces for such coupling. However, monitoring curvature-driven sorting of membrane components...
Dynamin I, a prototype GTPase controlling membrane remodeling in cells, converts the energy of nucleotide hydrolysis into elastic stress driving membrane fission. The energy transduction requires the concerted action of many dynamin subunits, however, it remains unclear how many subunits, and how they are coordinated in time and space. Using lipid...