Eugene Voropay

Eugene Voropay
Belarusian State University | BSU · Department of Laser Physics and Spectroscopy

Prof.

About

25
Publications
760
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77
Citations
Additional affiliations
January 1997 - present
Belarusian State University
Position
  • Head of Department

Publications

Publications (25)
Article
A laser atomic emission multichannel spectrometer (LAEMS) with an achromatic optical configuration is developed for research and educational purposes. The new spectrometer fits all the requirements for equipment for laser atomic emission spectroscopy, and has a number of advantages owing to the features of the design and technical characteristics o...
Article
The paper presents the results of studies of the spectral properties of a photosensitizer based on indotricarbocyanine dye when accumulating in tissues of experimental animals. Using laser fluorescence spectroscopy, the in vivo and ex vivo fluorescence spectra of tissue-localized indotricarbocyanine dye were obtained for different time counts after...
Article
Full-text available
Spectral and luminescent properties of an indotricarbocyanine dye are studied in solutions and after deposition on quartz or silicon substrates. It is found that the dye molecules self-assemble in aqueous EtOH solutions to form H*-aggregates. The absorption band of the H*-aggregates shows a hypsochromic shift of 192 nm (5291 cm–1) relative to the a...
Article
The effect of nitrogen defects in natural and synthetic diamond single crystals on the position and half-width of the fundamental Raman band was investigated. Samples containing the main types of nitrogen lattice defects at impurity contents of 1–1500 ppm were studied. The parameters of the Stokes and anti-Stokes components in Raman spectra of crys...
Article
Full-text available
We have studied the feasibility of using an indotricarbocyanine dye as a marker for the efficacy of photodynamic therapy (PDT) of cancers with the photosensitizer Photolon®. We have established that on exposure to laser emission at λ = 667 nm with an exposure dose of 100 J/cm2, we observe that the Photolon® concentration drops by about a factor of...
Article
Full-text available
The possibility for double pulse LIBS in the process of a direct layer-by-layer analysis of the titanium-based PVD-coatings on polished flat blank samples of steel and silicon and also of the TiAlN/TiN-coating on a milling cutter is considered. A method is proposed to control thickness of the radiation evaporated layer by defocusing the laser beam...
Article
Regularities in the generation of singlet oxygen sensitized by the indotricarbocyanine dye HITC with I- and ClO4 (-) anions in highly and slightly polar solvents were studied as functions of dye concentration (C-d). The yield of singletoxygen formation (gamma(Delta)) by HITC (I-) increased in slightly polar solvents as its concentration increased....
Article
Results of studies on the photonics of HITC indotricarbocyanine dye molecules with I–, Br–, and ClO4– counterions were presented. Introduction of an additional salt (tetrabutylammonium bromide) (10–2 M) to slightly polar solutions of the tricarbocyanine dye was shown to cause significant changes in the dye photophysical and photochemical characteri...
Article
The propagation processes of the plasma excited by double laser pulses in multicomponent copper alloys have been investigated. The methods to study direct and reverse substance deposition from the erosion plume have been developed. The spatial heterogeneity of the brass and bronze ablative plasma composition has been exhibited. With the use of lase...
Article
We present the results for studies of the spectral luminescence properties of a symmetric indotricarbocyanine dye (PD1) in HeLa tumor cells and animal tissues in vivo during a photochemotherapy session and after the end of the session. We have established that when the dye is exposed to light in tumor tissues, changes occur in the position and half...
Article
It is found that when indotricarbocyanine dye in HeLa cells is exposed to photons with different energies the efficiency of cell damage is wavelength independent provided the photosensitizer absorbs the same number of photons per unit time. In vivo animal experiments with two strains of tumor show that when the wavelength of the irradiating light i...
Article
The paper presents recent experimental results on the peculiarities of fluorescence and transient absorption exhibited by indotricarbocyanine dyes in solutions of different nature. The dynamics of transient absorption spectra of the molecules under study is analyzed within the framework of the concept of intra- and intermolecular vibrational relaxa...
Article
In low-polarity solvents the yield of the formed singlet oxygen is higher for the molecules of polymethine dyes (photsensitizers used in chemotherapy), with the anions which contribute to the ionic equilibrium accenting towards the increased portion of contact ion pairs and also with the anions containing heavy atoms.
Article
Full-text available
As demonstrated by the performed studies, the molecules of tricarbocyanine dye in vivo are localized in the low-permittivity region of the medium, predominantly in the form of contact ion pairs. Comparison of the experimental data and numerical simulation results has revealed that deformation of the dye fluorescence spectrum upon photochemotherapy...
Article
Full-text available
To evaluate the effect of cell oxygenation on photocytotoxicity of a novel tricarbocyanine indolenine dye covalently bound to glucose (TICS). HeLa cells were incubated with 5 microM TICS, 2 h later irradiated by laser at 740 nm with a light dose of 10 J/cm(2), delivered at a power density of 10, 20, 25 or 30 mW/cm(2), in air or in argon atmosphere,...
Article
In this paper we describe a compact, portable light-emitting diode (LED)-based fiber-optic system allowing in vivo diffuse reflectance spectra registration in visible and near IR spectral range at two distances between illuminating and collecting fibers. The construction of fiber optic probe is adapted for endoscopy application. We further report t...
Article
Investigation of the spectral properties of polymethine dyes in organic solvents, water, nutritious media and cell cultures at various concentrations has demonstrated that the tumor cells contain monomers of the dye molecules. Pharmacokinetics of the different dyes has been studied both in vivo and in vitro. After incubation of a cell culture in th...
Article
Investigated polymethine dye TICS has near IR bands of fluorescence and absorption within the transparency region of biological tissues. It can be detected up to 1.5 cm from the surface of the skin. The intensity of a fluorescence signal of TICS is linear for doses up to 2 mg/kg in both tumor and muscle tissue. The ratio of an intensity of light in...
Article
Photophysical and photochemical properties of five recently synthesized tricarbocyanine dyes have been investigated. The dyes investigated showed a capability for accumulation in HeLa cells. It was shown that the dyes accumulated in cells mainly in a monomeric form. Dark toxicity of dyes In vitro was studied and photodynamic efficiency of the five...

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