Etiane M Hundertmarck Saccol

Federal University of Santa Maria · Department of Physiology and Pharmacology

We analysed the effects of quercetin-containing diet on blood parameters, antioxidant status and pituitary hormone expression in silver catfish. Diets containing three concentrations of quercetin (0, 0.15 and 0.30%) were provided to fish once a day. The results indicated that quercetin did not promote any significant change on the haematological an...

The aim of this study was to determine oxidative stress parameters in the liver and gill of Brazilian flounder juveniles (307.0 ± 16.0 g and 30.0 ± 4.0 cm) submitted to different water temperature (17.1, 23.0 and 28.8ºC) for 72 h and maintained at salinity 25‰. After the acclimation of 7 days, in 23ºC, fish were transferred to 200 L tanks containin...

Inadequate stocking densities (e.g. high stocking density) activated stress system, affecting the metabolism of lipids, carbohydrates and proteins. The aim of this study was to evaluate the effects of adding essential oil of Myrcia sylvatica (EOMS) in the diet of Sparus aurata juveniles held at different stocking densities. Juvenile specimens were...

Aquaculture activities promote stress situations that decrease fish welfare. In this sense, the objective of this study was to evaluate the effects of adding essential oil of Myrcia sylvatica (EOMS), a substance that has been used to mitigate activation of stress system in other teleost, in the diet of gilthead sea bream (Sparus aurata). Juveniles...

The effects of adding rutin to the diet (0, 0.15 or 0.30 %) of silver catfish for 21 days on blood parameters, oxidative stress biomarkers and pituitary hormones expression were investigated. Fish that received the diet containing 0.15 % rutin exhibited reduced plasma cortisol levels. The levels of lipid peroxidation were lowered in the all tissues...

It is unknown whether the flavonoid rutin can protect the silver catfish liver in response to exposure to a known stressor, such as the prophylactic usage of the antimicrobial agent oxytetracycline. Thus, the current study aimed to assess the effect of rutin incorporation into the silver catfish diet formulation on oxytetracycline-induced liver oxi...

The effects of dietary supplementation of graded level (0, 0.25, 0.5, 1.0, and 2.0 ml/kg diet) of Citrus aurantium essential oil (EOCA) on the growth, metabolic, and oxidative parameters of silver catfish (Rhamdia quelen) were investigated in a 60‐day growth trial. Fish fed with 2.0 ml EOCA per kg exhibited significantly better growth performance t...

The effects of pre-transport handling and addition of essential oil of Myrcia sylvatica (EOMS) during transport on stress pathways activation in Rhamdia quelen were investigated. Fish (n = 400, 25.2 ± 2.9 g) were captured in production ponds and transferred to 100-L tank (density 100 g L− 1). After 24 h, 10 fish were sampled (before transport group...

The effects of diet supplemented with Myrcia sylvatica essential oil (EOMS) on growth and stress tolerance to different stocking densities were assessed in Sparus aurata. Initially, three experimental groups were established: i) control, ii) 1.0 and iii) 2.0 mL EOMS kg dry feed-1. After 90 days, nine fish per group were anesthetized, weighed and sa...

Protective or ameliorative effects of quercetin on the oxytetracycline (OTC) induced oxidative stress and presence of OTC residues in the muscle of silver catfish (Rhamdia quelen) were assessed. Fish were divided into four different experimental groups and received the following experimental diets for 14 or 21 days: (i)-control; (ii)-quercetin; (ii...

Ocimum gratissimum L. (known for its relaxant/sedative effects and antimicrobial properties) and Hesperozygis ringens (Benth.) Epling (known for its anti-parasitic properties) are two plants belonging to the family Lamiaceae. Currently, studies have demonstrated that the essential oils (EO) of these two plants present anesthetic and sedative activi...

We examined the effects of dietary supplementation for 21 days with different levels (0, 0.25 and 2.0 ml/kg) of the Aloysia triphylla essential oil (EOAT) on silver catfish (Rhamdia quelen). Cortisol levels were lower in fish fed EOAT at 2.0 ml/kg diet, and lactate levels were lower in those fed at both doses. Glucose, alanine aminotransferase, asp...

Objective: To investigate the effects of rapid anesthesia and long-term sedation with the essential oils (EOs) of Myrcia sylvatica (EOMS) and Curcuma longa (EOCL) on biochemical and oxidative parameters in matrinxã. Study design: Prospective, randomized, laboratory experiment. Animals: A total of 72 matrinxã (Brycon amazonicus) adults weighing...

Long-term administration of valproic acid (VPA) is known to promote reproductive impairment mediated by increase in testicular oxidative stress. Vitamin E (VitE) is a lipophilic antioxidant known to be essential for mammalian spermatogenesis. However, the capacity of this vitamin to abrogate the VPA-mediated oxidative stress has not yet been assess...

Valproic acid (VPA) is a drug widely use for the treatment of epilepsy in both children and adults. Evidence suggests that long-term use of VPA may lead to an impairment in the male reproductive function. Oxidative stress is considered to play a major role in VPA associated toxicity. In the present work, we demonstrated that the natural antioxidant...

Anaesthetic substances are necessary to reduce fish stress during aquaculture activities. The objectives of this study were: (i) to determine the efficacy of essential oils (EOs) of Myrcia sylvatica (EOMS) and Curcuma longa (EOCL) as anaesthetics for Colossoma macropomum and (ii) to evaluate the effects of rapid anaesthesia and long-term sedation (...

Aquaculture practices include several procedures as capture, handling and transport, which cause stress in fish. Anesthetics or sedative substances have been used to reduce this stress. The aim of this study was to evaluate the effects of essential oil of Myrcia sylvatica (EOMS) in the water on stress system activation in the silver catfish Rhamdia...

Morphometry of gills and antioxidant/oxidant status in gills, brain, liver and blood of Rhamdia quelen sedated with propofol were studied. The purpose was to investigate structural and functional responses upon administration of the drug in order to validate its use for the species. The fish were exposed to 0, 0.4 or 0.8 mg L−1 propofol for 1, 6 or...

Long-term intake of aspartame at the acceptable daily ingestion dose causes oxidative stress in the rat kidney through the dysregulation of glutathione homeostasis. N-acetylcysteine (NAC) provides the cystein required for the production of GSH, being effective in treating disorders associated with oxidative stress. The aim of this research was to i...

Long-term intake of aspartame at the acceptable daily dose causes oxidative stress in rodent brain mainly due to the dysregulation of glutathione (GSH) homeostasis. N-Acetylcysteine provides the cysteine that is required for the production of GSH, being effective in treating disorders associated with oxidative stress. We investigated the effects of...

Responses to anaesthesia with essential oil (EO) of Aloysia triphylla (135 and 180 mg L−1) and tricaine methanesulfonate (MS222) (150 and 300 mg L−1) were assessed in silver catfish. Exposure to the anaesthetics elicited a stress response in the species. In the case of MS222, it was displayed as a release of cortisol into bloodstream, elevation in...

Aquatic animals are naturally exposed simultaneously to environments with different concentrations of humic acid (HA) and seasonal or daily variations of dissolved oxygen (DO) levels. This study investigated the effects of simultaneous exposure to different HA and DO levels on plasma ion levels and some hematological and oxidative parameters in dif...

The growth, metabolic and blood parameters and oxidative stress biomarkers effects of adding Lippia alba essential oil (EO) to the diet (0 = control, 0.25, 0.5, 1.0 or 2.0 mL EO per kg diet) of juvenile silver catfish were investigated for 60 days. Liver and muscle were used to measure the glucose, glycogen and lactate levels. Lipid peroxidation (L...

This study aimed to evaluate oxidative stress parameters in juvenile tambaqui (Colossoma macropomum) exposed to 3.88 mg l(-1) Mn(2+) for 96 hours. Biomarkers of oxidative stress, such as thiobarbituric acid reactive substances (TBARS), superoxide dismutase (SOD), catalase (CAT), and glutathione-S-transferase (GST) activities, as well as content of...

Hyperthyroidism may lead to a loss of sperm motility and an increase in oxidative stress (OS) in testes and may cause male reproductive disorders. Thus, the use of compounds with antioxidant properties may be a strategy for preventing these disorders. The effect of resveratrol (RSV) on sperm motility and on variables of the antioxidant status in th...

The effect of parboiled rice (PR) and white rice (WR) diets on oxidative stress (OS) parameters was investigated in the kidneys of rats with streptozotocin-induced diabetes (40 mg kg(-1), iv). The experimental groups (n=8) were control fed with PR (CPR), control fed with WR, diabetic fed with PR, and diabetic fed with WR. After 30 days of treatment...

Aquatic organisms are continuously exposed to environmental variations, which can lead to physiological and biochemical alterations. Leporinus macrocephalus, known as piavuçu, is a migratory species that may be exposed to variations in dissolved oxygen levels. Studies evaluating oxidative changes undergone by this species in these conditions are sc...