Esther Vögelin

Esther Vögelin
Inselspital, Universitätsspital Bern

About

199
Publications
13,787
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2,586
Citations
Citations since 2016
64 Research Items
1448 Citations
2016201720182019202020212022050100150200250
2016201720182019202020212022050100150200250
2016201720182019202020212022050100150200250
2016201720182019202020212022050100150200250

Publications

Publications (199)
Article
Background: Surgical exploration of the lumbosacral plexus is challenging. Previously described approaches reach from invasive open techniques with osteotomy of the ilium to laparoscopic techniques. Objective: To describe a novel surgical technique to explore lumbosacral plexopathies such as benign nerve tumors or iatrogenic lesions of the lumbosa...
Article
We retrospectively reviewed the charts of patients treated for bite injuries in our clinic from 2014 to 2019. The time from the bite event to surgery, duration of hospital stay, duration of antibiotic treatment, complications, incapacity for work and costs were analysed. Cat bites were compared with the other bite injuries and were found to be more...
Article
Full-text available
Purpose Phalangeal fractures are the most common injuries in humans and account for approximately 10% of all fractures. With plate fixation, anatomic reduction is achievable in most cases, but extension lag is seen in up to 67%. Intramedullary headless screw offers treatment of unstable proximal phalangeal fractures using a minimally invasive proce...
Article
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Introduction The aim of this study was to analyze primary flexor tendon repair results in zones I and II, comparing the rupture rate and clinical outcomes of the controlled active motion (CAM) protocol with the modified Kleinert/Duran (mKD) protocol. Materials and methods Patients who underwent surgery with traumatic flexor tendon lacerations in z...
Article
Aims of the study: This study set out to examine the association between current subspecialty (paediatric and hand surgery) consultation practice for children with hand and finger injuries presenting to a tertiary paediatric emergency department and length of stay in the paediatric emergency department. Also, incidence and injury pattern of hand a...
Article
Ultrasonography in hand surgery offers the option of imaging trauma consequences or degenerative problems in the wrist and fingers, involving bones, joints, ligaments, tendons, annular pulley, carpal and digital changes, soft masses, and foreign bodies including dynamic changes during motion. In the hands of the treating surgeon, ultrasonography al...
Article
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Background The purpose of this study is to assess outcomes in flexor pollicis longus tendon repairs with 6-strand core sutures with and without circumferential sutures. Methods A 6-strand core suture technique with and without circumferential sutures was used. Thirty-three patients were summarized in the C group (circumferential group) and 16 pati...
Article
The autologous synovium is a potential tissue source for local induction of chondrogenesis by tissue engineering approaches to repair articular cartilage defects such as they occur in osteoarthritis. It was the aim of the present study to ascertain whether the aging of human osteoarthritic patients compromises the chondrogenic potential of their kn...
Article
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The field of vascular anomalies (VA) has been subject to changes during the last few decades. The current classification of the International Society for the Study of Vascular Anomalies (ISSVA) offers a simple diagnostic structure. Hand surgeons commonly appear to have limited exposure to VA. Already recognized for more than 120 years, pyogenic gra...
Article
We present the case of a 31-year-old woman who was referred with a 12-month history of a tumor on the ulnar side of her dominant right hand. The eventual histopathologic diagnosis was an atypical pleomorphous lipomatous tumor, an entity that has only been recently classified in the World Health Organization Classification of Soft Tissue and Bone Tu...
Article
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Introduction Reconstruction of the scapho-lunate (SL) ligament is still challenging. Many different techniques, such as capsulodesis, tendon graft and bone-ligament-bone graft have been described to stabilize reducible SL dissociation. If primary ligament repair alone is not possible, an additional stabilizer is needed to achieve scapho-lunate stab...
Preprint
Full-text available
The autologous synovium is a potential tissue source for local induction of chondrogenesis by tissue engineering approaches to repair articular cartilage defects such as they occur in osteoarthritis. It was the aim of the present study to ascertain whether the aging of osteoarthritic patients compromises the chondrogenic potential of their knee-joi...
Article
Background: The lymphatic system plays an active role in modulating inflammation in autoimmune diseases and organ rejection. In this work, we hypothesized that the transfer of donor lymph node (LN) might be used to promote lymphangiogenesis and influence rejection in vascularized composite allotransplantation (VCA). Methods: Hindlimb transplanta...
Article
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Purpose Lunotriquetral (LT) instability is uncommon and few biomechanical analyses of the condition exist. For chronic LT instabilities, arthrodesis has long been the treatment of choice but has a high risk for nonunion. The aim of this study was to evaluate an alternative treatment option using a bone–ligament–bone graft in a cadaver model and com...
Article
Full-text available
The consensus wrist index (CWI) is a new method that combines existing, valid, and established assessment tools to create a comprehensive representation of the patient’s functional situation. Patient rated outcome measures (PROMs) are used to gain the patient’s perspective. Both objective measurements and PROMs are performed at regular intervals to...
Article
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Finally, the 2c level of evidence-based practice - to treat Complex Regional Pain Syndrome of the upper extremity with SRM (cohort n=48) – suggests that this method is a good alternative to other conservative treatments (Packham et al., 2018). As to medical malpractice in nerve injury (Krauss et al., 2020), rehabilitation of neuropathic pain should...
Article
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Background: The lymphatic system may play an important role in local immunomodulation in vascularized composite allotransplantation (VCA). Currently, there is no standardized VCA model that includes the regional draining lymphatic tissue. The aim of this study was to develop a rapid and efficient orthotopic hindlimb transplantation model in rats t...
Article
Introduction Vascularized nerve grafts (VNG) may offer an advantage in peripheral nerve regeneration by avoiding ischemic damage and central necrosis observed in non-VNG, particularly for the treatment of large and long nerve defects. However, surgical complexity, donor site morbidity and limited nerve availability remain important drawbacks for th...
Article
Pain assessment of CRPS in Hand Therapy Abstract. Pain massively controls everyday life of affected persons. In case of a nerve being damaged, pain becomes more complex, as the trophism of the affected skin area may significantly be altered in addition to loss of sensibility and / or motor function. Quantifying pain is, therefore, difficult. Nevert...
Article
Treatment of acute injuries of the hand Abstract. Injuries to the hand are a common presentation in primary care units. When accurately assessed, many open injuries may be handled in the emergency department without referral to a hand surgery specialist. We would like to give some recommendations on how to treat the most frequent injuries like lesi...
Article
Full-text available
The consensus wrist index (CWI) is a new method that combines existing, valid, and established assessment tools to create a comprehensive representation of the patient’s functional situation. A group of 18 health care professionals met to discuss and define measures for the evaluation of the wrist. The CWI requires that both objective measurements...
Article
High-resolution ultrasonography is an important tool used for the diagnosis and management of inflammatory arthritis of the hand and wrist. This imaging modality has also proven its utility in the evaluation of traumatic lesions of tendons, nerves, annular pulleys, ligaments, and carpal and digital injuries and for detecting foreign bodies and caus...
Chapter
Using an endoscopically assisted technique, we are able to identify all possible compression sites and where required to release them. The entry point, located 5 cm proximal of the radial humeral epicondyle between the brachioradialis/brachialis and triceps muscle, allows endoscopic exposure of the superficial and deep radial nerve branches distal...
Chapter
Radial nerve injuries, at different levels, have been reported in swimming, tennis, golf, weight lifting, and several kinds of throwing sports. The mechanisms of injury include direct trauma and compression injuries. Radial tunnel syndrome is an uncommon pathology. However 5–8% of patients with chronic lateral epicondylitis have involvement of the...
Article
Full-text available
Introduction Finger proximal interphalangeal joint (PIP) reconstruction after the destruction of parts of the joint remains challenging. Surgical techniques include implant arthroplasty, arthrodesis, free vascularized joint transfer, and non-vascularized bone and joint transfer. This study analyzes our experience after non-vascularized transfer in...
Article
Introduction: Acellular nerve allografts are viable treatment modality for bridging nerve gaps. Several small studies have demonstrated equal results to autologous grafts, however there is lacking information regarding outcomes for wider indications. The aim of this retrospective case series was to evaluate the outcomes of patients treated with a...
Article
Metacarpal neck fractures with severe displacement are commonly treated surgically with intramedullary Kirschner wires. We present the results of treatment of fifth metacarpal neck fractures using a light curable intramedullary photodynamic polymer (IlluminOss™, IlluminOss Medical Inc., East Providence, RI, USA). Twenty-nine patients with isolated...
Article
Full-text available
Vascularized composite allotransplantation (VCA), such as hand and face transplantation, is emerging as a potential solution in patients that suffered severe injuries. However, adverse effects of chronic high-dose immunosuppression regimens strongly limit the access to these procedures. In this study, we developed an in situ forming implant (ISFI)...
Article
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Introduction In Switzerland, collagenase Clostridium histolyticum therapy (CCH) for Dupuytren’s disease was introduced in 2011. This study analyzes possible differences between CCH and limited fasciectomy (LF) in terms of range of motion, patient satisfaction and postoperative rehabilitation. Materials and methods This retrospective study included...
Article
Background: Implant-related infections in hand surgery are dreaded complications, potentially leading to loss of finger joint function or amputation. Knowledge about the clinical presentation and treatment concepts of these infections is limited. The aim of this study is to present a consecutive series of patients with implant-related infections o...
Article
Purpose of review: The long-term adverse effects of immunosuppressive treatment, the high rate of acute rejection and the development of chronic rejection are the main factors preventing a wider clinical application of vascularized composite allotransplantation (VCA). Targeted immunosuppression using innovative drug delivery systems (DDS) may help...
Article
Full-text available
Background: Routine application of vascularized composite allotransplantation is hampered by immunosuppression-related health comorbidities. To mitigate these, we developed an inflammation-responsive hydrogel for local immunosuppression. Here, we report on its long-term effect on graft survival, immunological, and toxicological impact. Methods:...
Article
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Introduction: Human ear reconstruction is recognized as the emblematic enterprise in tissue engineering. Up to now, it has failed to reach human applications requiring appropriate tissue complexity along with an accessible vascular tree. We hereby propose a new method to process human auricles in order to provide a poorly immunogenic, complex and...
Article
Background: Despite various exisiting monitoring methods, there is still a need for new technologies to improve the quality of post-operative evaluation of digital replantation. The purpose of the study is using a laser Doppler imaging device (Easy-LDI) as an additional tool to assess perfusion. In this method, the changes in the frequency of the...
Article
Purpose: Psychological factors have shown to be associated with treatment outcomes in hand injury patients. This study aimed to investigate the role of health locus of control (HLOC) and its dimensions internal, social-external, and fatalistic-external HLOC in treatment outcomes of hand injury patients. Method: One hundred thirty-two consecutive...
Article
Full-text available
Background Perilunate dislocations and fracture-dislocations are a subcategory of the carpal instability complex. Herein, we report our university hospital experience with this complex injury. The goal of our study was to find predictive factors and quantify the development of arthritis and lunate necrosis. We tried to measure the impact of arthrit...
Article
Background In order that the thumb as the most important part of a functioning hand can assume its functions, it must be stable, sufficiently long, sensitively innervated and sufficiently able to move. Objective Alternatives to a thumb reconstruction, demonstration of a thumb lengthening procedure using a semi-circular distraction fixator and deve...
Article
Background Immunosuppressive therapies derived from solid organ transplantation are effective in promoting survival of vascularized composite allotransplantation (VCA), but they cause serious side effects that are difficult to justify for this non–life-saving procedure. Unlike solid organ transplantation, hand and face transplants offer the possibi...
Article
Background: In pig-to-human xenotransplantation, interactions between human natural killer (NK) cells and porcine endothelial cells (pEC) are characterized by recruitment and cytotoxicity. Protection from xenogeneic NK cytotoxicity can be achieved in vitro by the expression of the non-classical human leukocyte antigen-E (HLA-E) on pEC. Thus, the a...
Article
Revascularization of an amputated limb within 4–6 h is essential to avoid extensive ischemia/reperfusion (I/R) injury leading to vascular leakage, edema and tissue necrosis. I/R injury is a pathological inflammatory condition that occurs during reperfusion of an organ or tissue after prolonged ischemia. It is characterized by a complex crosstalk be...
Article
Introduction: The management of volar plate avulsion fractures in the context of a stable joint and a bony fragment of less than 30% has traditionally been conservative. This study was performed to assess volar plate healing with high-resolution ultrasound in order to provide early full mobilization. Material and methods: Between January 2012 an...
Article
Objective: During the last decade, face allotransplantation has been shown to be a revolutionary reconstructive procedure for severe disfigurements. However, offer to patients remains limited due to lifelong immunosuppression. To move forward in the field, a new pathway in tissue engineering is proposed. Background: Our previously reported techn...
Article
Buy Article Permissions and Reprints Zusammenfassung Zur Daumenrekonstruktion nach traumatischer Amputation hat sich auch die Kallusdistraktion mittels Distraktionsfixateur etabliert. Die Wahl des geeigneten Verfahrens hängt von der Amputationshöhe, dem Alter, Beruf und vom funktionellen Anspruch des Patienten ab. Wir berichten über unsere Erfahru...
Article
Full-text available
Background Pyogenic arthritis of the small joints (SJA) of the hand and wrist is a known but poorly described entity. The objective of this work was to characterize the clinical presentation, antimicrobial treatment and surgical interventions of native SJA treated in our tertiary centre. Methods According to predefined variables, medical records o...
Article
Rubber band syndrome is a rare entity seen in younger children mainly in communities where rubber bands are worn around the wrist for decorative purposes. When the band is worn for a long duration, it burrows through the skin and soft tissues resulting in distal edema, loss of function, and even damage to the neurovascular structures. These symptom...
Article
Full-text available
Niklaus Egloff,1,2 Barbara Wegmann,1 Bettina Juon,3 Stefanie Stauber,1 Roland von Känel,2,4 Esther Vögelin3 1Division of Psychosomatic Medicine, Department of General Internal Medicine, Inselspital Bern University Hospital, 2Department of Clinical Research, University of Bern, 3Department of Plastic and Hand Surgery, Inselspital Bern University Hos...
Conference Paper
Background and Hypothesis: Side effects associated with systemic immunosuppression remain a pace-limiting obstacle to widespread adoption of vascularized composite allotransplantation (VCA). Unlike most solid organ transplantations, VCA offer unique possibilities to monitor rejection and deliver immunosuppressive drugs directly into the graft, in p...
Conference Paper
Introduction: During the last decade vascularized composite allotransplantation (VCA) has been established as clinical practice with excellent functional and aesthetic outcomes. Minimization of immunosuppression is one of the most important open questions in the field. Drug delivery systems able to release immunosuppressive drugs directly into the...
Data
Currently, systemic immunosuppression is used in vascularized composite allotransplantation (VCA). This treatment has considerable side effects and reduces the quality of life of VCA recipients. We loaded the immunosuppressive drug tacrolimus into a self-assembled hydrogel, which releases the drug in response to proteolytic enzymes that are overexp...
Article
The thickness of 210 A1 pulleys of 21 male and female healthy volunteers in two different age groups (20-35 y and 50-70 y) were measured by ultrasound. In a second group, the thickness of 15 diseased A1 pulleys and 15 A1 pulleys of the corresponding other hand of 10 patients with the clinical diagnosis of trigger finger were measured by ultrasound....
Article
Purpose: To assess the visual performance of Swiss hand surgeons in an environment similar to their workplace. The influence of Galilean (lenses only) and Keplerian loupes (lenses and prisms), the surgeon's age, and the credibility of a self-assessment of his or her own optical performance were evaluated. Methods: Sixty-three hand surgeons betwe...
Article
The loss of the upper extremity implicates a grave insult in the life of the involved person. To compensate for the loss of function different powered prosthetic devices are available. Ever since their first development 70 years ago numerous improvements in terms of size, weight and wearing comfort have been developed, but issues regarding the cont...
Article
Patients in whom conventional peroneal nerve repair surgery failed to reconstitute useful foot lift need to be evaluated for their suitability to undergo a concomitant tendon transfer procedure or nerve transfers. To report our first clinical experience with nerve transfers for persistent traumatic peroneal nerve palsy. Between 2007 and 2013, 8 pat...
Article
Persistent traumatic peroneal nerve palsy, following nerve surgery failure, is usually treated by tendon transfer or more recently by tibial nerve transfer. However, when there is destruction of the tibial anterior muscle, an isolated nerve transfer is not possible. In this article, we present the key steps and surgical tips for the Ninkovic proced...
Article
Dysregulation of the coagulation system due to inflammatory responses and cross-species molecular incompatibilities represents a major obstacle to successful xenotransplantation. We hypothesized that complement inhibition mediated by transgenic expression of human CD46 in pigs might also regulate the coagulation and fibrinolysis cascades and tested...
Book
Full-text available
Das Buch enthält alle notwendigen Grundlagen zur zuverlässigen sonografischen Diagnosestellung von Erkrankungen und Veränderungen der Hand. Nach einer umfassenden Einführung in die physikalischen Grundlagen der Sonografie und die sonografische Anatomie der Hand samt Varianten, werden entzündliche, degenerative, kompressive und traumatische Veränder...