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Publications
Publications (115)
This study compares the one-year outcomes of standalone Ahmed glaucoma valve (AGV) implantation and standalone Paul glaucoma implant (PGI) in adult patients with primary and secondary glaucoma. A retrospective, single-center, comparative study was conducted on adult patients who underwent standalone PGI and AGV at the University Medical Center Main...
PURPOSE. Restricted fetal growth is associated with impaired neurodevelopment in childhood. We examined the effects of fetal growth restriction, fetal overgrowth, and other perinatal parameters on optic nerve head (ONH) morphology in term-born
children and adolescents.
METHODS. This retrospective cohort study with a prospective ophthalmologic exami...
Purpose
To compare the peripapillary retinal nerve fiber layer (pRNFL) thickness of large optic discs in children (LOD-C) with normal sized optic discs in children (NOD-C) and large optic discs in adults (LOD-A).
Methods
We included 127 eyes per group (n = 381). Optic discs were considered large if the Bruch's membrane opening (BMO) area was ≥2.5...
Background: The aim of this study was to evaluate the short-term efficacy and safety of the Paul Glaucoma Implant (PGI) in pediatric eyes diagnosed with glaucoma following congenital cataract surgery (GFCS). Methods: A retrospective, single-center, descriptive study was conducted on consecutive children diagnosed with GFCS who underwent PGI implant...
Purpose
This study assesses morphological characteristics using SD-OCT in patients with hypotony maculopathy (HM) following glaucoma filtering surgery and evaluates the results of its treatment.
Material and Methods
Retrospective analysis of all HM patients between January 2019 and March 2023. Inclusion criteria consisted of both pre-operative and...
Purpose
To investigate the longitudinal change in intraocular pressure (IOP) over 5 years and its relationship with cardiovascular parameters in a population-based sample in Germany.
Methods
The Gutenberg Health Study is a prospective, observational, single-center cohort study. The sample was equally stratified for sex, residence, and age decade....
Glaucoma is not a rare entity but because very few symptoms occur and visual field defects are frequently first recognized at a late stage, a large proportion of glaucoma diseases remain undetected. The aim of this study was to identify the proportion of undiagnosed glaucoma in German population-based cohort studies and to contextualize them in the...
Purpose
To assess long-time results of primary surgical treatment in children with glaucoma after congenital cataract surgery.
Methods
A retrospective study of 37 eyes from 35 children with glaucoma after congenital cataract surgery, who underwent surgery between 2011 and 2021 at the Childhood Glaucoma Center, University Medical Center Mainz, Germ...
Prcis:
After the open bleb revision following PreserFlo, the mean postoperative intraocular pressure (IOP) was lowered from 26.4 ± 9.9 mm Hg to 12.9 ± 5.6 mm Hg at 1 month and 15.9 ± 4.1 mm Hg at 12 months.
Purpose:
The purpose of this study was to evaluate the effectiveness and safety of an open bleb revision with mitomycin-C (MMC) for bleb fib...
Purpose:
To investigate the association between intraocular pressure (IOP) and climate parameters.
Methods:
The Gutenberg Health Study (GHS) is a population-based cohort study in Mainz, Germany. Participants underwent two comprehensive ophthalmologic examinations (baseline visit and five-year follow up) including non-contact tonometry, objective...
Glaucoma in infancy and childhood is a rare disease. An immediate diagnosis and treatment are absolutely necessary to prevent blindness of affected children. Childhood glaucoma is characterized by a heterogeneous phenotype: besides primary congenital glaucoma, secondary types often exist and the individualized treatment requires an experienced inte...
Background: To evaluate the long-term efficacy and safety of modified canaloplasty versus trabeculectomy in open-angle glaucoma. Methods: In total, 210 subjects with open-angle glaucoma were included. 70 were treated with Mitomycin C-augmented modified canaloplasty with enhanced subconjunctival filtration and 140 with Mitomycin C-augmented trabecul...
Objective
To evaluate the long-term outcomes of trabeculectomy (TE) surgery in a large cohort with a minimum follow-up of 3 years.
Design
Retrospective cohort study.
Setting
University Eye Hospital, Germany.
Participants
Three hundred and seventy-nine patients with open-angle glaucoma underwent TE with mitomycin C (MMC) between January 2013 and...
The aim of this study was to investigate the effects of atropine on patients’ perception of visual quality after trabeculectomy. Forty patients undergoing standard trabeculectomy with mitomycin C were enrolled in this prospective randomized study. All surgeries were conducted at the ophthalmology department of the University Medical Center of Mainz...
Objective
The aim of this prospective pilot study is to establish an initial database to register patients diagnosed with different types of childhood glaucoma and the set-up of a national registry for childhood glaucoma (ReCG) in Germany. 28 children with different types of diagnosed childhood glaucoma, who were admitted and treated at the Childho...
Background
Trabeculectomy (TE) remains one of the most frequently performed glaucoma procedures. This surgery enables sufficient reduction of intraocular pressure (IOP) and freedom from using eye drops; however, complication management and time-consuming postoperative care make many ophthalmic surgeons reluctant to include TE in their treatment reg...
Trabeculectomy represents the glaucoma surgical procedure that achieves the greatest reduction in intraocular pressure and enables a low pressure regulation especially in normal pressure glaucoma. For the beginner the operation is challenging due to potential intraoperative and postoperative difficulties. With this in mind this article explains how...
Purpose:
This study investigated whether prematurity and associated factors or prenatal growth restriction have long-term effects on the peripapillary retinal nerve fiber layer (pRNFL) in adulthood.
Design:
Retrospective cohort study.
Methods:
The Gutenberg Prematurity Eye Study (GPES) is a retrospective cohort study with a prospective ophthal...
Zusammenfassung
Glaukomerkrankungen im Kindesalter sind selten. Da ohne Behandlung in der Regel die Erblindung eintritt, ist eine umgehende Diagnosestellung und Therapie von höchster Bedeutung. Die Heterogenität der Erkrankung erfordert eine genaue Kenntnis der möglichen Ursachen und deren individuelle Behandlung. Dieser Artikel soll einen Überblic...
Objective:
We aimed to compare intraocular pressure (IOP) measurements using iCare® PRO rebound tonometry (iCare) and Perkins applanation tonometry (Perkins) in childhood glaucoma subjects and healthy children and the influence of anaesthesia depth, age and corneal thickness.
Material:
Prospective clinical, case-control study of children who und...
Purpose:
The purpose of this study was to investigate the association between intraocular pressure (IOP) and ocular geometry.
Methods:
The Gutenberg Health Study is a population-based cohort study in Mainz, Germany. Study participants underwent a comprehensive ophthalmologic examination including noncontact tonometry, objective refraction, optic...
Childhood glaucoma is a heterogeneous disease and can be associated with various genetic alterations. The aim of this study was to report first results of the phenotype–genotype relationship in a German childhood glaucoma cohort. Forty-nine eyes of 29 children diagnosed with childhood glaucoma were prospectively included in the registry. Besides me...
Purpose
This study assesses short-term intraocular pressure (IOP) change in the fellow eye of glaucoma patients after mitomycin C–augmented trabeculectomy, filtering canaloplasty, or PreserFlo™ microshunt implantation in the treated eye.
Materials and methods
Retrospective chart review of 235 glaucoma patients (235 eyes) was performed. Patients un...
Introduction
Neonates and young infants with diagnosed or highly suspected glaucoma require an examination under anaesthesia to achieve accurate intraocular pressure (IOP) measurements, since crying or squinting of the eyes may increase IOP and lead to falsely high values. IOP considerably depends on perioperative variables such as haemodynamic fac...
Purpose:
To assess surgical success and the post-operative development of intraocular pressure between XEN45® gelstent, Preserflo® MicroShunt and trabeculectomy with mitomycin C.
Methods:
Data from 105 eyes from 105 patients of matched cases with refractory open-angle glaucoma, who underwent surgery between January 2019, and August 2020, were ev...
Purpose
To evaluate long-term results of glaucoma surgery in newborn and infants with glaucoma.
Methods
Seventy-nine eyes of 52 children (age: 3 weeks–15.3 years) with primary congenital or secondary glaucoma treated between 2015 and 2017 were included. The median follow-up time was 3.9 years. Conventional probe trabeculotomy, 360° catheter-assist...
Background
Glaucomatous eyes often show strong intraocular pressure (IOP) fluctuations and individual measurements at different time points are necessary for personalized therapy. To survey IOP variations 48-hours diurnal and nocturnal IOP measurements were performed on two consecutive days. Aims of this study were to investigate the short-term rep...
Open-angle glaucomas are a group of chronic progressive optic nerve neuropathies with a gonioscopic open anterior chamber angle. They are one of the main causes of visual impairment and blindness in industrialized countries. The aim of this article is to discuss and evaluate the epidemiology and risk factors for the development of open-angle glauco...
An amendment to this paper has been published and can be accessed via the original article.
Background
Severe congenital ophthalmological malformations and glaucoma might be an important occasional feature in patients with Coffin-Siris syndrome (CSS), especially Coffin-Siris syndrome 9 (CSS9, OMIM #615866) caused by SOX11 mutation. Recently, primary (open-angle) glaucoma was described in two children with the most common form of Coffin-Si...
PRéCIS:: Treatment of leakage with ocular hypotony after trabeculectomy with MMC can be safely achieved through conjunctival patch alone or combined with donor scleral graft in cases of melted underlying sclera.
Purpose:
To report outcomes of two surgical approaches for treating ocular hypotony in eyes with blebs with late-onset leakage after sta...
Background
Central retinal vein occlusion is a variable disease pattern. Preliminary stages of a complete occlusion of the central vein, wich are subsumed under the term venous stasis retinopathy, may occur as transient blurred vision and with subtle alterations of the fundus. Course and prognosis are benign, visual acuity usually recovers. By now,...
Purpose: Low birth weight is associated with altered retinal development in childhood, including reduced peripapillary retinal nerve fiber layer (pRNFL) thickness. However, to the best of our knowledge, no population-based study has analyzed the relationship of low birth weight to pRNFL thickness in adulthood. The purpose of this study was to inves...
Background:
Glaucoma is a group of chronically progressive disorders of the optic nerve. In this article, we present the epidemiology of and risk factors for glaucoma, as well as the diagnostic work-up and treatment options.
Methods:
This review is based on pertinent publications retrieved by a selective search in Medline and the Cochrane Librar...
Purpose:
Using a bleb-grading system clinically facilitates long-term follow-up of patients with previous glaucoma surgery. Clinical evaluation of these patients can be challenging for untrained ophthalmologists. Morphological bleb configuration might influence planning of follow-up visits in glaucoma patients due to different and individual progn...
Purpose:
Since the role of short- and long-term intraocular pressure (IOP) fluctuation as a predictor of glaucoma progression is still controversial, the purpose of this study was to investigate the role of IOP fluctuation in a non-selected patient cohort.
Materials and methods:
Two-hundred and forty eyes of 120 glaucoma patients (51% female) wi...
Purpose:
To evaluate the distribution of peripapillary retinal nerve fiber layer thickness as measured by optical coherence tomography and its associations with ocular parameters in a population-based setting.
Methods:
In the population-based Gutenberg Health Study, 1974 subjects from the Mainz-Bingen region were scheduled for ophthalmologic exa...
Purpose
To determine feasibility, efficacy, and safety of ab externo 360-degree trabeculotomy with illuminated microcatheter for congenital glaucoma.
Patients and Methods
The postoperative results of 36 eyes in 23 consecutive patients who underwent 360-degree trabeculotomy for primary congenital glaucoma (PCG) or secondary congenital glaucoma usin...
Background
Glaucoma is a neurodegenerative disease, leading to thinning of the retinal nerve fibre layer (RNFL). The exact influence of ocular, cardiovascular, morphometric, lifestyle and cognitive factors on RNFL thickness (RNFLT) is unknown and was analysed in a subgroup of the Gutenberg Health Study (GHS).
Methods
Global peripapillary RNFLT was...
Objectives:
To investigate the results of an adaptive approach of bleb revision surgery for late onset hypotony after trabeculectomy with mitomycin C due to bleb leakage and/or scleral melting.
Methods:
29 eyes of 27 patients, aged 63.8±11.7 years with hypotony maculopathy (IOP ≤6▒mm Hg) due to late onset bleb leakage and/or scleral melting afte...
We report a case of a rare complication after trabeculotomy combined with a small trabeculectomy with mitomycin C in a young patient with juvenile glaucoma. The patient underwent uneventful surgery. However, postoperatively, he experienced a long-lasting hypotony with the need of two revision surgeries and two short episodes of high intraocular pre...
Purpose
Intraocular pressure (IOP) fluctuation is considered as a risk factor for glaucoma progression. We investigated IOP values and IOP fluctuation before and after trabeculectomy (TE) with mitomycin C (MMC) measured by 48-hour diurnal-nocturnal-IOP-profiles (DNP).
Methods
Pre- and postoperative DNPs of 92 eyes undergoing primary TE with MMC we...
Introduction:
Suprachoroidal hemorrhage is a rare, but potentially vision-threatening event with poor long-term visual prognosis. At present, there is disagreement whether surgical intervention or conservative treatment is superior in the management. We report on a case of spontaneous resolution of severe SCH after needling procedure in the only e...
Purpose:
To compare the diagnostic performance and evaluate diagnostic agreement for early glaucoma detection between a confocal scanning laser ophthalmoscope (CSLO) and a spectral-domain optical coherence tomography (SD-OCT).
Patients and methods:
Fifty-five eyes of 55 open-angle glaucoma patients and 42 eyes of 42 healthy control subjects were...
Background:
The exact pathogenesis of open angle glaucoma and ocular hypertension remains unclear. Hemodynamic influences are discussed as potential risk factors and the choroid may play an important role in the pathogenesis of open angle glaucoma or ocular hypertension. The current study investigates peripapillary choroidal thickness and choroida...
Purpose:
To determine whether baseline Heidelberg Retina Tomograph (HRT) measurements of the optic disc are associated with the development of open-angle glaucoma (OAG) in individuals with ocular hypertension in the European Glaucoma Prevention Study (EGPS).
Design:
Retrospective analysis of a prospective, randomized, multicenter, double-masked,...
Purpose:
To compare the outcome of fornix-based trabeculectomy with mitomycin C (MMC) using 2 different sizes of subconjunctival preparation (36 mm² compared with 72 mm²).
Methods:
Prospective, randomized interventional case series.
Study population:
Patients 18 to 85 years of age with open-angle glaucoma and progressive visual field defects u...
Background:
To compare the diagnostic accuracy and to evaluate the correlation of optic nerve head and retinal nerve fiber layer thickness values between Fourier-Domain optical coherence tomography (FD-OCT), confocal scanning laser ophthalmoscopy (CSLO), and scanning laser polarimetry (SLP) for early glaucoma detection.
Patients and methods:
Nin...
The aim of this study was to evaluate the correlations between general anthropometric features and cardiovascular parameters and central corneal thickness (CCT) in an adult European cohort.
Analysis was based on a Gutenberg Health Study cohort that included 5000 subjects (2540 male, 2460 female), aged 35 to 74 years at enrollment. The participants...
To evaluate the distribution of central corneal thickness (CCT) in a large German cohort and to analyse its relationship with intraocular pressure and further ocular factors.
Population-based, prospective, cohort study.
The Gutenberg Health Study (GHS) cohort included 4,698 eligible enrollees of 5,000 subjects (age range 35-74 years) who participat...
Intraocular pressure (IOP)-lowering therapy has been shown to arrest or retard the progression of optic neuropathy typical for glaucoma and can, thus, be described as neuroprotective. At present, six classes of medical therapy are employed, namely parasympathomimetics, alpha/beta-sympathomimetics, β-blockers, carbonic anhydrase inhibitors, α2-adren...
Purpose:
To describe the study design and baseline factors of the Heidelberg Retina Tomograph ancillary study within the EGPS. Furthermore, to examine the relationship between HRT optic disc topographic measurements and baseline demographic and ocular factors.
Methods:
Four hundred and eighty-nine ocular hypertensive participants were included....
Background:
To evaluate the relationship and agreement between standard automated perimetry (SAP) and Matrix frequency doubling technology (Matrix-FDT) in subjects with ocular hypertension and healthy control subjects.
Methods:
Forty-four eyes of 44 ocular hypertensive subjects and 29 eyes of 29 healthy age-matched control subjects were included...
Purpose:
To describe the distribution of intraocular pressure (IOP) and its association with ocular features and cardiovascular risk factors in an adult European cohort.
Design:
Population-based, cross-sectional study.
Participants:
This analysis was based on a Gutenberg Health Study (GHS) cohort that included 4335 eligible enrollees from amon...
Purpose:
To present the 4-year follow-up results in the surgical treatment of hypotony following trabeculectomy with mitomycin C in glaucoma patients with additional flap sutures.
Design:
Retrospective interventional case series.
Methods:
Since 2006, 53 patients with hypotony maculopathy attributable to overfiltration following glaucoma surger...
Purpose:
During donor tissue preparation for Descemet stripping automated endothelial keratoplasty (DSAEK), either microkeratome or femtosecond laser can be used for intrastromal cutting. We compared morphological and functional outcomes after DSAEK using both cutting techniques.
Methods:
In this retrospective study, 22 uneventful DSAEK surgerie...
PURPOSE:
Flicker defined form perimetry (FDF) and frequency doubling technology perimetry (FDT) are alleged to detect glaucoma at an earlier stage than standard automated perimetry (SAP). It is the purpose of this study to investigate the structure-function relationship between FDF, FDT, SAP, and confocal scanning laser ophthalmoscopy (cSLO) in pat...
Purpose:
Flicker defined form perimetry (FDF) and frequency doubling technology perimetry (FDT) are alleged to detect glaucoma at an earlier stage than standard automated perimetry (SAP). It is the purpose of this study to investigate the structure-function relationship between FDF, FDT, SAP, and confocal scanning laser ophthalmoscopy (cSLO) in pa...
Retinal nerve fiber layer (RNFL) thinning and optic nerve head cupping
are key diagnostic features of glaucomatous optic neuropathy. The higher
resolution of the recently introduced SD-OCT offers enhanced
visualization and improved segmentation of the retinal layers, providing
a higher accuracy in identification of subtle changes of the optic disc...
To evaluate the diagnostic ability of Fourier-domain optical coherence tomography (FD-OCT) measurements in glaucoma patients, patients with ocular hypertension, and normal subjects.
Ninety-three participants with open-angle glaucoma (OAG), 58 patients with ocular hypertension (OHT), and 60 healthy control subjects were included in the study. All st...
To evaluate the learning curve and fatigue effect of flicker defined form (FDF) perimetry.
Prospective cross-sectional study.
One hundred forty-one eyes of 75 healthy subjects were included in the study. Every subject was measured 3 times on 3 different days within 3 months. Differences among the tests were analyzed for mean sensitivity (MS), mean...
To evaluate the inter- and intraobserver variability of ocular response analyzer (ORA) measurements, namely corneal-compensated intraocular pressure (IOPcc), corneal resistance factor (CRF) and corneal hysteresis (CH).
One randomly chosen eye of 46 healthy volunteers was included in this study. Three clinical observers performed three consecutive m...
At present time domain optical coherence tomography (TD-OCT) plays a less important role in glaucoma diagnostics and is used mainly for macula diagnostics. The Fourier domain optical coherence tomography (FD-OCT) with enhanced resolution has new options to detect glaucoma changes. This new technology is referred as frequency domain or spectral doma...
Tonometry is the measurement of intraocular pressure (IOP). Normal IOP values range from 10 to 21 mmHg (15.5 mmHg+/-2 SD). They are influenced by various factors, including the patient's position during measurement, central corneal thickness, corneal diameter and curvature, rigidity of the cornea, and the cornea's state of hydration. Until now, Gol...
Glaucoma is a disease in which death of retinal ganglion cells is associated with loss of visual function. The gold standard for visual field testing has been standard automated perimetry (SAP). However, up to 30-50% of retinal ganglion cells must be lost before a scotoma is detected with SAP. Therefore, investigators have been interested in findin...
Scanning laser polarimetry (SLP) is another technology for early glaucoma diagnosis. This technique (represented in the GDx from Carl Zeiss Meditec, Jena, Germany) is based on polarimetry and measures the retinal nerve fiber layer (RNFL) thickness. Compared with previous instruments without customized corneal compensation, the variable corneal comp...
The Heidelberg Retina Tomograph (HRT) is a glaucoma diagnosis system that provides fast, noninvasive topographic information about the optic nerve head, the neuroretinal rim, and the thickness of the nerve fiber layer. With these capabilities, it is one of the leading laser systems for detecting glaucoma. Statistical methods such as the Moorfields...
In addition to optic disc assessment at the slit lamp and the use of imaging devices for glaucoma diagnosis, optic disc photography is widely used in clinical practice. The advantages of stereophotography are a permanent recording of the optic disc status especially used for serial evaluation of discs, good visibility of the peripapillary region an...
At present time domain optical coherence tomography (TD-OCT) plays a less important role in glaucoma diagnostics and is used mainly for macula diagnostics. The Fourier domain optical coherence tomography (FD-OCT) with enhanced resolution has new options to detect glaucoma changes. This new technology is referred as frequency domain or spectral doma...
In addition to optic disc assessment at the slit lamp and the use of imaging devices for glaucoma diagnosis, optic disc photography is widely used in clinical practice. The advantages of stereophotography are a permanent recording of the optic disc status especially used for serial evaluation of discs, good visibility of the peripapillary region an...
Tonometry is the measurement of intraocular pressure (IOP). Normal IOP values range from 10 to 21 mmHg (15.5 mmHg±2 SD). They are influenced by various factors, including the patient’s position during measurement, central corneal thickness, corneal diameter and curvature, rigidity of the cornea, and the cornea’s state of hydration. Until now, Goldm...
Glaucoma is a disease in which death of retinal ganglion cells is associated with loss of visual function. The gold standard for visual field testing has been standard automated perimetry (SAP). However, up to 30–50% of retinal ganglion cells must be lost before a scotoma is detected with SAP. Therefore, investigators have been interested in findin...
A new, fast-threshold strategy, German Adaptive Thresholding Estimation (GATE/GATE-i), is compared to the full-threshold (FT) staircase and the Swedish Interactive Thresholding Algorithm (SITA) Standard strategies. GATE-i is performed in the initial examination and GATE refers to the results in subsequent examinations.
Sixty subjects were recruited...
A serious complication following trabeculectomy with mitomycin C (MMC) is intraocular hypotony with hypotony maculopathy, papilledema, flattening of the anterior chamber, corneal decompensation and a decrease in visual acuity. We describe a new simple surgical technique for the treatment of hypotony maculopathy following trabeculectomy with MMC.
In...
The aim of this study was to compare the intraocular pressure (IOP) results measured by the iCare rebound tonometer with those obtained by the Goldmann applanation tonometer (GAT) over a wide range of IOP values. Furthermore, the comfort level of the iCare measurement was evaluated.
The study included 75 eyes of 75 patients. The patients were divid...
Case reportAn 82‐year‐old multimorbid man presented with a fist‐sized painless tumour of the left orbit (fig 1A 1A).). Computed tomography demonstrated an orbital mass clearly demarcated from the surrounding tissue (fig 1B 1B).). After biopsy, the neoplasm was classified as a borderline‐malignant extrapleural solitary fibrous tumour. Therefore, a t...
To compare the interthreshold and intrathreshold strategy agreement of visual field end point criteria for standard automated perimetry (SAP) with the full-threshold (FT) algorithm and the Swedish interactive threshold algorithm (SITA).
Prospective, longitudinal cohort study.
The interstrategy group included a randomly selected eye of 173 participa...
To determine the spatial relationship in neuroretinal rim parameter values between eyes in ocular hypertensives, glaucoma suspects, and glaucoma patients.
Observational-cross-sectional study.
A total of 334 eyes of 167 patients were included. All patients underwent confocal scanning laser ophthalmoscopy imaging in both eyes. Intereye concordance ra...
Assessment of optic disk size is an important, but often overlooked, component of the diagnostic evaluation for glaucoma. Measured values of optic disk size vary with the measurement technique utilized. Available methods for disk size measurement and their respective strengths and limitations will be discussed. Further, actual disk size varies with...
To investigate the agreement in the measurement of intraocular pressure (IOP) obtained by dynamic contour tonometry PASCAL (DCT-PASCAL) and Goldmann applanation tonometry (GAT) in glaucoma eyes and healthy eyes with different central corneal thickness (CCT).
Prospective cross-sectional study.
In a randomized order, three consecutive IOP measurement...
To assess whether the combined use of both structural and functional tests improves discrimination between healthy and glaucomatous eyes over either type of testing alone.
Observational cross-sectional study.
One hundred twenty-three eyes of 123 participants enrolled in the Diagnostic Innovations in Glaucoma Study.
Because both structural and funct...
To assess the strength of the association between retinal nerve fiber layer (RNFL) thickness and optic disc topography measured with confocal retinal tomography (HRT II; Heidelberg Engineering, Dossenheim, Germany), optical coherence tomography (StratusOCT; Carl Zeiss Meditec, Inc., Dublin, CA), and scanning laser polarimetry (GDx with variable cor...
To determine the overlap in defective visual field locations between the right and left eyes of primary open-angle glaucoma patients.
Cross-sectional retrospective analysis of data from a prospectively designed longitudinal study.
Patients with glaucomatous optic neuropathy in at least 1 eye and 2 consecutive reliable standard automated perimetry f...
To compare inter-eye patterns of visual field (VF) loss on standard automated perimetry (SAP) in patients with glaucomatous optic neuropathy.
Observational cross-sectional study.
Four-hundred-and-ninety eyes of 245 patients with glaucomatous optic neuropathy in at least one eye defined by masked stereophoto review were included. Patients had two re...
Background
The aim of the study was to compare intraocular pressure (IOP) measurements between Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT) during product certification according to the international requirements for ophthalmic instruments (tonometers, ISO 8612:2001).
Methods
The study included 160 eyes of 80 subjects. I...
The aim of the study was to compare intraocular pressure (IOP) measurements between Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT) during product certification according to the international requirements for ophthalmic instruments (tonometers, ISO 8612:2001).
The study included 160 eyes of 80 subjects. IOP measurements wer...
Purpose
To compare the ability of the nerve fiber analyzer (GDx) and the retinal thickness analyzer (RTA) to discriminate between glaucomatous and healthy eyes.
Methods
Thirty-seven glaucoma patients (early to moderate severity) and 34 healthy controls were included. Glaucoma patients were defined as those with two repeatable abnormal visual field...
To investigate the association between patterns of visual field (VF) loss and retinal nerve fiber layer (RNFL) thickness measurements.
Observational cross-sectional study.
One hundred twenty-one glaucoma patients and 65 healthy subjects from the Diagnostic Innovations in Glaucoma Study (DIGS) were included. All glaucoma patients had repeatable abno...
