• Home
  • Esmail Doustkhah
Esmail Doustkhah

Esmail Doustkhah
Koç University

PhD

About

114
Publications
15,907
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
2,494
Citations
Introduction
Esmail Doustkhah joins Koç University, of the top Universities in Turkey, in 2022 as Senior Research Fellow. Since 2016, he has been at the National Institute for Materials Science (NIMS), Japan, working around designing hybrid 2D and mesoporous materials. His most recent publications are about nanoporous materials, 2D materials, and their applications in various fields such as (photo)(electro)catalysis.

Publications

Publications (114)
Article
Green rust (GR) is a mixed-valent iron mineral and structurally constitutes a family of layered double hydroxides that have attracted widespread attention in environmental and energy applications. However, despite the ubiquity of GR in environments and its potential instrumental role in life’s emergence, its instability against oxidation has limite...
Article
Template-directing strategies for synthesising metal–organic frameworks (MOFs) have brought about new frontiers in materials chemistry due to the possibility of applying control over crystal growth, morphology and secondarily generated pores. In particular, hard templates have resulted in performance breakthroughs in catalysis, secondary ion batter...
Article
Designing an excellent solar photocatalyst based on TiO2 without an external cocatalyst such as Pt remains unresolved despite its exceptional potential for renewable energy production. Here, we report a state-of-the-art solar-driven photocatalytic Cl-doped rutile TiO2, in nanosheet morphology with (110) facets, for H2 production from water splittin...
Article
Oxide perovskites have emerged as an important class of materials with important applications in many technological areas, particularly thermocatalysis, electrocatalysis, photocatalysis, and energy storage. However, their implementation faces numerous challenges that are familiar to the chemist and materials scientist. The present work surveys the...
Article
Full-text available
Here, we control the surface activity of hydroxyapatite (HAp) in wastewater treatment which undergoes peroxodisulfate (PDS) activation. Loading the catalytically active Cu species on HAp forms a copper phosphate in the outer layer of HAp. This modification turns a low active HAp into a high catalytically active catalyst in the dye degradation proce...
Article
We show here that MOF-5, a sample Zn-based MOF, can uniquely transform into distinct zinc oxide nanostructures. Inspired by the interconversion synthesis of zeolites, we converted MOF-5 into nanocrystalline ZnO. We found the conversion of MOF-5 into ZnO to be tunable and straightforward simply by controlling the treatment temperature and choosing a...
Article
Despite the ubiquity of aqua–Fe(III) complexes in biological enzymes and their useful properties and cost-effectiveness, artificially stabilising these fleeting molecules for practical uses remains challenging. Herein, we demonstrate that a dimeric aqua–Fe(III) species can be stabilised using a flexible microporous layered silicate to produce a whi...
Article
Full-text available
Layered double hydroxides (LDHs) constitute a unique group of 2D materials that can deliver exceptional catalytic, optical, and electronic performance. However, they usually suffer from low stability compared to their oxide counterparts. Using density functional calculations, we quantitatively demonstrate the crucial impact of the intercalants (i.e...
Chapter
For the past two centuries, the range of synthesized organic compounds have increased excessively including raw materials, plastics, fuels, detergents, and other useful substances. However, pollution and other hazards have resulted from the production of these compounds as well as remaining in the environment after usage, which is a serious concern...
Chapter
Inevitably, the terms “materials” and “products” differ from one another. To comprehend their potentiality in terms of mechanical, chemical, physical, and biological properties, the specifications of basic materials are verified in the laboratory. Then, materials are changed or contrived into products. As a definite form of a product, its thickness...
Chapter
This chapter aims to provide an overview of the most practical and attractive protocols that demonstrate the syntheses of 1,5-benzodiazepines and 1,5-benzothiazepines using various readily available starting materials and catalysts under mild reaction conditions.
Chapter
This chapter explains the present pharmacological knowledge of a FDA-approved 1,5-benzodiazepine, clobazam, including general mechanism of action, metabolic pathway, pharmacokinetic profile, recommended dosages, potential side effects, and drug-drug interactions.
Chapter
This chapter briefly explains the history, mechanism of action, and medical applications of benzodiazepines and benzothiazepines.
Chapter
This chapter explains the present pharmacological knowledge of twelve FDA-approved 1,4-benzodiazepines including general mechanisms of action, metabolic pathways, pharmacokinetic profiles, potential adverse effects, and drug-drug interactions. Furthermore, recommended dosages of these drugs for the management of anxiety, insomnia, seizures, and alc...
Chapter
This chapter describes the biological behavior of 1,4-benzodiazepines and 1,4-benzothiazepines through their detailed molecular effects on various cellular receptors.
Chapter
In this chapter, the structural and chemical properties of 1,5-benzodiazepines and 1,5-benzothiazepines through available literature are discussed. Most of these studies have been focused on the tautomerism, conformational isomerism, and chemical reactivity of these pharmaceutically important fused heterocycles.
Chapter
This chapter discusses the current knowledge of the chemical structures, conformational and electronic features of different types of 1,4-benzodiazepines and 1,4-benzothiazepines.
Chapter
This chapter gives an overview of recent developments in the synthesis of 1,4-benzodiazepines and 1,4-benzothiazepines utilizing readily available reactants under practical synthetic procedures.
Article
Rapid, accessible, and highly accurate biosensors for the detection of addictive and abused drugs are needed to reduce the adverse personal and societal impacts of addiction. Modern sensors that utilize next‐generation technologies, e.g., nanobiotechnology and nanoarchitectonics, have triggered revolutionary progress in the field as they allow accu...
Article
Degradation of contaminants of emerging concern in aqueous media using bimetallic oxides is a promising novel strategy that requires engineering new catalytic routes in bimetallic oxides to perform advanced oxidation; however, several challenges to synthesizing and developing such materials with enhanced, sustainable catalytic features are still be...
Article
Full-text available
Hybridisation of mesoporous organosilicas (MO) to reinforce the surface capability in adsorption and stabilisation of noble metal nanoparticles is of great attention in generating/supporting noble metal within their matrices and transforming them into efficient heterogeneous catalysts. Here, we used a unique hybrid of organic-inorganic mesoporous s...
Article
The architectural design of nanocatalysts plays a critical role in the achievement of high densities of active sites but current technologies are hindered by process complexity and limited scaleability. The present work introduces a rapid, flexible, and template-free method to synthesize three-dimensional (3D), mesoporous, CeO2-x nanostructures com...
Preprint
Full-text available
Microporous organosilicas assembled from polysilsesquioxane (POSS) building blocks are promising materials that are yet to be explored in-depth. Here, we investigate the processing and molecular structure of bispropylurea bridged POSS (POSS-urea), synthesised through the acidic condensation of 1,3-bis(3-(triethoxysilyl)propyl)urea (BTPU). Experimen...
Article
Full-text available
Microporous organosilicas assembled from polysilsesquioxane (POSS) building blocks are promising materials that are yet to be explored in-depth. Here, we investigate the processing and molecular structure of bispropylurea bridged POSS (POSS-urea), synthesised through the acidic condensation of 1,3-bis(3-(triethoxysilyl)propyl)urea (BTPU). Experimen...
Preprint
Full-text available
Hybridization of mesoporous organosilica (MO) to reinforce the surface capability in adsorption and stabilization of noble metal nanoparticles are of great attention in generating noble metal-based catalysts. Here, we used a unique hybrid of organic-inorganic mesoporous silica which in pore profile pattern was similar to the well-known mesoporous s...
Article
Full-text available
Because rutile TiO2 has a potential application of its effective utilization of indoor illumination for environmental purification, effort has been devoted to synthesizing advanced rutile materials. Here we report a...
Article
Background: Synthetic chemists have utilized base catalyzed halogen dance reactions, ever since its discovery by Bunnet et al. Many modifications under various conditions have enabled synthetic chemists to build substituted hetero-cyclic targets with rich structural diversity. Methods: Using DFT-Cam-B3LYP/ land2dz computations and focused on Hanne...
Article
First reported by Joseph Bunnet et al., base-catalyzed halogen dance reaction has puzzled chemists for decades, to come up with new ideas regarding the mechanism of this chemical reaction. A series of deprotonation followed by fast metal-halogen exchanges are among the most recent mechanisms reported so far. Using density functional theory, DFT, co...
Article
Full-text available
In this paper, we have studied the in silico interaction of angiotensin-converting enzyme 2 19 (ACE2) human receptor with two bioactive compounds, i.e., nicotine and caffeine, via the molecular 20 dynamic (MD) simulations. The simulations reveal the efficient blocking of ACE2 by caffeine and 21 nicotine in the exposure to spike (S) protein of sever...
Article
Here, a nanoporous N-dopedgraphitic carbon (NC) obtained via the pyrolysis of the zeolitic imidazolate framework-67 (ZIF-67) in the N2 atmosphere and then etched with hydrofluoric acid (HF) to remove the cobalt particles. The carbonized imidazoles in the framework of the ZIF-67 converted to the formation of N-doped graphitic sheets. The N2 adsorpti...
Article
We synthesized a new organosiloxane bridge on the basis of an isocyanurate derivative through a simple melt-fusion approach by the reaction of 3-isocyanatopropyltriethoxysilane (IPTES) with 1,3,5-tris(2-hydroxyethyl)-1,3,5-triazinane-2,4,6(1H,3H,5H)-trione (THEIC). The obtained carbamate-isocyanurate-based organosiloxane bridge precursor was used f...
Preprint
Full-text available
Base-catalyzed halogen dance reaction, has puzzled chemists ever since, to come up with new ideas regarding the mechanism of this beautiful chemical transformation. Series of fast metal-halogen exchanges are among the most recent mechanisms. Using DFT-Cam-B3LYP/ land2dz computations and focused on Halogen Dance (HD) reactions of bromobenzene deriva...
Article
Raising the capability of supporting and suppressing the leaching possibility to a very insignificant level has still remained challenging for some class of transition metals, i.e. Ni 2+. Here we present the covalent functionali-sation of macrocyclic ligand, 4,13-diaza-18-crown-6 (kryptofix 22), on the surface of carbon nanotube (CNT), leading to a...
Article
The main aim of the present investigation was the intercalation of WS2 nanosheets in the structure of ceria (CeO2) to be used for the efficient catalytic destruction of tylosin (TYL) as a macrolide antibiotic in water. As-synthesized heterostructured catalyst was placed in a sono-reactor (40 kHz and 300 W) in order to degrade TYL through the sonoca...
Article
Ultrasensitive sensing of organic compounds has attracted a great deal of attention in recent years. Here, we report air-stable cobalt decorated-nanoporous carbon (Co/ZIF-C), derived from the pyrolysis of zeolitic imidazolate based metal-organic framework (ZIF-67), for ultrasensitive detection of flavonoid, rutin. In line with this, we examined the...
Article
Full-text available
Thiourea-bridged organosiloxane is used to synthesize a periodic mesoporous organosilica (PMO). Since this PMO has an S-enriched surface, owing to thiourea functional groups, it exhibits strong coordination toward Pt ions, and it shows a high tunability in the Pt nanoparticles size. This hybrid mesoporous material is employed as a catalyst in the e...
Article
Microporous materials are, nowadays, majorly known as zeolites and metal-organic frameworks. Although layered inorganic solids like swelling-type clay minerals are also considered microporous materials because of the expandable and modifiable interlayer nanospace, well-defined open micropores still remain difficult to form there, which can cause di...
Article
Full-text available
Sourcing our ever-increasing demand for energy to power our high-paced and energy-thirsty industries poses a never-ending challenge. Therefore, many academic, industrial, and government entities put forward tremendous efforts in search of clean and sustainable energy resources. Taking into account the availability, safety, and efficiency of formic...
Cover Page
Full-text available
For the full version, please see https://pubs.acs.org/doi/abs/10.1021/acsanm.9b01508
Research
Full-text available
A good chance to enhance the visibility of your works in 2D materials area by submitting to this special issue which is going to compile recent reports about 2D materials for catalysis
Article
Full-text available
Hydroxyapatite (HA) is one of the basic materials in the construction of the bones. In this study, we investigate the new Nano-architecture of HA in a polymer base material like PLA to 3d printing of the bones. We have introduced a simple soft-template approach for Nano-plates from HA. HA nanostructure has been produced which has a thickness and di...
Article
Among many biodegradable and biocompatible biopolymers, polyhydroxyalkanoates (PHAs), generated by microorganisms, have highly attracted attention in various fields due to their unique physicochemical properties. So far, various types of progress have been made in environmental and engineering fields by employing PHAs. Among many applications, empl...
Article
Mesoporous aluminosilica is a unique structure for catalysis due to Lewis acidity of aluminum. Here, we design a new catalyst by merging periodic mesoporous organosilica with aluminosilica into its structure instead of mere silica. The employed organosilica bridge in this synthesis is a thiourea based organosiloxane precursor which has a unique fea...
Article
The synthesis of mesoporous organosilicas (MOs) using co-condensation for a high ratio of a long and flexible chained organosiloxane bridge with silica precursor (e.g. tetraethylorthosilicate (TEOS)) is a complex and challenging task. By complementing the experimental characterisations with density functional calculations, The critical ratio of the...
Article
Nanosheets are a burgeoning class of two-dimensional nanomaterials due to their fascinating properties and diverse applications. Mesoporous nanosheets are considered as a next generation nanosheets because of their superior properties. Here, we report an unprecedented type of mesoporous nanosheets, microporous silicate nanosheets with vertically al...
Article
Full-text available
The design of hydroxyapatite (HA) nanoarchitecture is critical for fabricating artificial bone tissues as it dictates the biochemical and the mechanical properties of the final product. Herein, we incorporated a simple hard-template approach to synthesise single crystal nanoplates of HA. We used the 2D graphitic nitride (g-C3N4) material to prepare...
Article
Full-text available
The design of hydroxyapatite (HA) nanoarchitecture is critical for fabricating artificial bone tissues as it dictates the biochemical and the mechanical properties of the final product. Herein, we incorporated a simple hard-template approach to synthesise single crystal nanoplates of HA. We used the 2D graphitic nitride (g-C3N4) material to prepare...
Article
Full-text available
Immobilization of enzymes is a promising approach for the cost-effective application of enzymes. Among others, noncovalent but unleachable approaches for immobilization are one of the most favorable and crucial approaches. Herein, silica nanoparticles are modified by (3-aminopropyl)triethoxysilane (APTES) to generate amino-functionalized silica nan...
Chapter
Because graphene-based materials have a high surface area in interlayer space, there is a high tendency toward elimination of interlayer interactions through several methods. There are three distinct pathways to overcome the interlayer interaction: intercalation, pillaration, and exfoliation. In exfoliation, there is the least interaction between t...
Article
Herein, the efficient role of ultrasonic irradiation both in synthesis of Zr based porous coordination polymer (Zr-PCP) nanoparticles and boosting its catalytic activity, towards the benzimidazoles synthesis is represented. We use an amine based ligand (amino-terephthalate) for PCP and we exhibit that it can have a synergistic catalytic activity. I...
Article
Full-text available
A zwitterionic amino acid-like N-propyliminodiacetic acid (PIDA) organocatalyst supported to a heterogeneous surface (SBA-15/PIDA) based on iminodiacetic acid and mesoporous SBA-15, respectively was synthesized. The mesoporous hybrid catalyst was successfully characterized by SEM, TEM, TGA, FTIR, and EDS and employed in the three-component reaction...
Article
Full-text available
Sulfonic acid based mesostructures (SAMs) have been developed in recent years and have important catalytic applications. The primary applications of these materials are in various organic synthesis reactions, such as multicomponent reactions, carbon–carbon bond couplings, protection reactions, and Fries and Beckman rearrangements. This review aims...
Article
A mechanochemical protocol was applied to the synthesis of a magnetic material based on iron oxide nanoparticles and Al-SBA-15. Full characterization of the prepared Fe2O3/Al-SBA-15 evidenced the effective functionalization of the aluminosilicate surface. Particularly, TEM analysis revealed that the mechanochemical protocol did not considerable aff...
Article
Highly dispersed Pd nanoparticles ca. 2 nm in size are successfully synthesized within the mesochannels of a newly designed mesoporous organosilica containing thiourea-based bridges (TU-PMO) embedded within the pore walls. The supported Pd catalyst shows a superior activity and recyclability for the catalytic dehydrogenation of formic acid in water...
Article
Full-text available
Nowadays, giant organic molecules have taken a great attention in nanoarchitecturing of silica materials. Silica nanostructure binded dendrimers play a crucial role in the next‐generation technologies within many fields such as medicine, drug delivery, sensors, catalysis, water treatment, etc. This paper discusses silica nanostructures which are ar...
Article
Fe3O4@C core-shell nanoparticles were modified by (3-aminopropyl)triethoxysilane (APTES) to generate amine functionality in the surface. Then, the amine functional groups were converted to dithiocarbamate via post-modification with carbon disulfide. This nanostructure with new functional property was used to immobilize lipase (obtained from Yarrowi...
Article
This paper discusses the catalytic feature of apple pectin encapsulated Fe3O4 nanoparticles (Fe3O4-Pectin) which is prepared by co-precipitation of Fe(II/(III) ions in alkaline solution and supporting copper(II) sulfate. This process led to formation of magnetic nanoparticles within the network of pectin. It was used for immobilization of copper io...
Article
Full-text available
Catalytic behavior of perchloric acid when supported to mesoporous silica SBA-15 (SBA-15/HClO4) was investigated as a heterogeneous Bronsted acid. Its reactivity and leaching possibility were studied in cascade ring opening-cyclocondensation sequence of diketene and alcohol with aldehyde in the presence of either of urea or ammonium acetate. Result...
Article
Full-text available
Enclosing functional nanoparticles in stable inorganic supports is important for generating ultra-stable catalytic active sites with good performance and material utilization efficiency. Here we describe a simple method to synthesize ultra-thin Ag nanocrystals with dimensions that are defined by the ~1.4-nm 2D interlayer separating a layered silica...
Chapter
Nowadays, mesoporous silica (MS) materials have been considered good candidates for supporting and generating metal nanoparticles (NPs) inside their pores, owing to their high surface area, good stability, and tunable pore sizes. Encapsulation not only preserves and stabilizes metal NPs during the catalysis, it makes MS a nanoreactor in which the r...
Article
Full-text available
Metal-organic frameworks (MOFs) are crystalline solids formed by inorganic clusters or metal ions (generally transition metal) linked by bi- or multifunctional organic ligands. Exploiting the advantages of the MOFs including large surface area, high metal content, and flexibility in designing the active sites, would be an innovative idea to make no...
Article
This paper discloses the assembly and characterization of an advanced heterogeneous catalyst formulated as CuI@SBA-15/PrEn/ImPF6. It is based on a mesoporous silica SBA-15 skeleton which bears a supported ethylenediamine/CuI complex and covalently anchored imidazolium/PF6 ionic liquid. This catalyst was successfully applied in tandem methods for tr...
Article
A Fe3O4-chitosan (Fe3O4-CS) nanocomposite was prepared using an in situ approach via co‐precipitation of Fe²⁺ and Fe³⁺ under basic conditions, followed by carbon disulfide post‐modification and subsequent functionalisation with NH2-Fe³⁺ functionalities. The multifunctional magnetically separable nanomaterial was employed as catalyst in the room tem...
Article
In the present paper, porcine pancreas lipase (PPL) was immobilized to a new version of magnetite via a novel stepwise dithiocarbamate/chitosan-based method in alternation to glutaraldehyde. Magnetic chitosan nanocomposite was post-modified to produce dithiocarbamate moieties on the surface through amine functions. Then, immobilization of lipase wa...
Article
Immobilization of lipase was successfully achieved on the surface of magnetically separable Fe3O4/graphene oxide (GO) via a post-modification. This post modification was achieved in alternation to glutaraldehyde post-modification. The activity of immobilized lipase had not a significant loss in the activity while on the other hand, it is simply ext...
Article
In this work, a new catalyst based on Pd (II) supported SBA-15 has been has been introduced and discussed. The designed catalyst was characterised by Scanning electron microscopy (SEM), transmission electron microscopy (TEM), FT-IR, BET surface area analysis, thermo gravimetric analysis (TGA), Energy-dispersive X-ray spectroscopy (EDS) and atomic a...
Article
Full-text available
p>In this paper, silica nanoparticles with particle size of ~ 10-20 nm were selected as a support for the synthesis of Co<sub>3</sub>O<sub>4</sub> nanoparticles by impregnation of silica nanoparticles in solution of Co(II) in a specific concentrations and then calcination to 800 <sup>o</sup>C. This nanocomposite was then, used as a catalyst for oxi...