Eser Ozyurek

• Associate Professor of ObGyn
• Medical Doctor at Turkish Ministry of Health

Aims: Cervical cancer is one of the most common gynecological cancers and has poor outcomes. Although it is more easily detected through cervical cancer screening programs, studies on the interpretation of precancerous lesions and their future consequences are among the controversial issues in literature. Atypical squamous cells of undetermined sig...

Background To evaluate the efficacy of the preoperative ultrasonographic sliding sign in predicting intra-abdominal adhesions. Methods This was a single-center, double-blinded, prospective observational study undertaken from March and September 2021 on 110 patients with a history of previous abdominal surgery. All patients who were scheduled for l...

Introduction/Background It is a matter of debate whether there are other factors that may affect the results of colposcopic biopsy independent of cytology and humanpapilloma virus (HPV) genotype results. Therefore, we evaluated the effect of age and reproductive status on clinical outcomes in patients who underwent colposcopy. Methodology Patients...

Objective To investigate the efficacy of new endometriosis biomarkers in diagnosis and treatment. Methods Thirty women with Stage III-IV endometriosis who were given an indication for surgery and 49 control patients were compared. Preoperative and postoperative serum levels of Annexin A5 (ANXA5), soluble intercellular adhesion molecule-1 (sICAM-1)...

Objective: To determine the relationship between the cumulative effect of sequential clomiphene citrate (CC) treatments in unexplained infertile women with intercycle and intracycle serum hormone changes. Materials and methods: Patients who received CC 50 mg in the first cycle (group I, n=34) as ovulation induction and those who received CC 50 m...

Objective: To determine the relationship between the cumulative effect of sequential clomiphene citrate (CC) treatments in unexplained infertile women with intercycle and intracycle serum hormone changes. Materials and Methods: Patients who received CC 50 mg in the first cycle (group I, n=34) as ovulation induction and those who received CC 50 mg i...

Introduction. This study aimed to determine whether endocervical glandular involvement by squamous intraepithelial lesion would differ with respect to the depth of the excised specimen and analyze the related factors that may define endocervical glandular involvement among cases treated with cone biopsy. Methods. Between April 2016 and December 201...

Objectives: To examine the intra-cycle and inter-cycle hormonal changes in the clomiphene citrate (CC) cycle in women with unexplained infertility; and to determine the factors that may predict follicle development or CC failure. Study design: Descriptive study. Place and duration of study: This study was conducted at the Bagcilar Training and...

Aim: To analyze the risk factors of lymph node involvement in pure endometrioid type endometrial cancer and assess factors that necessitate lymphadenectomy. Methods: Patients who had been operated on due to endometrial cancer and whose final pathology was reported as pure endometrioid carcinoma between January 2014 and January 2020 were assessed...

Aim: Treatment of mixed type incontinence includes surgical and/or medical options. The efficacy of treatment frequently depends on the patient based choice. Thus, we aimed to compare treatment efficacy with UDI-6 and IIQ-7 questionnaire forms in groups with/without urodynamics in the diagnosis of mixed type incontinence. Material and Methods: In o...

Surgery can continue safely during the pandemic in a specialty hospital that does not accept COVID‐19‐positive patients.

Aim: Treatment of mixed type incontinence includes surgical and/or medical options. The efficacy of treatment frequently depends on the patient based choice. Thus, we aimed to compare treatment efficacy with UDI-6 and IIQ-7 questionnaire forms in groups with/without urodynamics in the diagnosis of mixed type incontinence.

Background: We aimed to investigate the impact of adopting an uterine manipulator (UM) on the postoperative (VL) and female sexual function index (FSFI) in patients undergoing abdominal hysterectomy (AH) for benign gynecological disease. Materials and Methods: Hysterectomies were performed with the Richardson technique; two variations, a UM or digi...

Objective: To demonstrate the laparoscopic excision technique of a juvenile cystic adenomyoma and show how the decidualization of ectopic endometrial tissue can lead to the misdiagnosis of a focus of ectopic pregnancy. Design: Description and step-by-step demonstration of the surgical procedure using a video recording (Canadian Task Force Classi...

Aim: Thyroid disorders have a crucial impact on maternal and fetal health during insulin resistance (IR) and vitamin D levels in different studies.We aimed to investigate the association between thyroid hormone levels and IR and vitamin D levels in pregnant women. Material and Methods: In this study, a total of 187 pregnant women between 5-39 gesta...

ABSTRACT Removal of uterus during laparoscopic hysterectomy (LH) is occasionally challenging and therefore sometimes requires morcellation. Morcellation techniques for hysterectomy can spread the cancer cells which were presumed benign preoperatively in to the abdomen or pelvis. Probability of an undetected malignity should not be disregarded and a...

OBJECTIVE: To investigate the difference in the effectiveness of controlled ovarian hyperstimulation and intrauterine insemination (COH+IUI) on pregnancy rates in patients with pri­mary and recurrent endome­triomas. STUDY DESIGN: Multi­ center, retrospective cohort study done in 3 tertiary referral centers. Included in the study were (1) primary i...

Endometriosis is an estrogen-dependent disease that affects 5 to 15% of women of reproductive age. Data from large-cohort and case-control studies indicate an increased risk for ovarian cancers in women with endometrioma. Recently, as an ovarian cancer biomarker, human epididymal secretory protein E4 (HE4) has been increasingly investigated in the...

p> Objective: Endometriosis is a common gynecological condition that affects many women of reproductive age worldwide and is a major cause of pain and infertility. Treatment of endometriosis can be either surgical, aiming to restore normal anatomy by removing endometriotic lesions, or hormonal. Various medical treatments with different doses, formu...

ABSTRACT Purpose: We investigated the optimal cut-off level for urinary neutrophil gelatinase-associated lipocalin (NGAL) in preeclamptic patients to confirm the diagnosis. Methods: Urinary NGAL concentrations were measured by specific enzyme-linked immunosor-bent assay (ELISA). Results: Patients with preeclampsia had significantly higher urinary N...

p> Objective: Owing to its high sensitivity and specificity, and because it is widely available, transvaginal ultrasonography is the first-line imaging test of choice used for the diagnosis of endometriosis. Ultrasonographic findings evaluated in conjunction with symptoms and signs may improve the diagnosis of endometriosis. Therefore, we hypothesi...

p> Objective: Owing to its high sensitivity and specificity, and because it is widely available, transvaginal ultrasonography is the first-line imaging test of choice used for the diagnosis of endometriosis. Ultrasonographic findings evaluated in conjunction with symptoms and signs may improve the diagnosis of endometriosis. Therefore, we hypothesi...

Aim To investigate the effectiveness of ovulation induction and intrauterine insemination (OI + IUI) in female patients with hypogonadotropic hypogonadism (HH), and to compare the outcomes of different stimulation protocols and cycle characteristics. Material and methods The outcomes of OI + IUI treatments in patients with HH diagnosed between 201...

Background: The obstetrics and gynecology literature has expanded in recent years to include clinical trials assessing the use of barbed sutures. The difficulty of intracorporeal suturing continues to be a barrier to a wider use of laparoscopy. Although the use of barbed sutures has been shown to ease the process of laparoscopic suturing considera...

An accurate prediction of abdominal wall adhesions would be extremely beneficial to help preventing injuries during the initial abdominal entry. Our aim was to evaluate the accuracy of the visceral slide test in predicting abdominal wall adhesions before surgery. One hundred fifty-five patients who underwent benign gynecologic surgery were prospect...

Objectives: The utilization of barbed sutures in laparoscopic hysterectomy has become popular among gynecologic sur-geons. Our aim was to compare the outcomes of two different techniques for closing the vaginal cuff with barbed sutures in laparoscopic hysterectomies. Material and methods: A retrospective study was completed on 202 patients who u...

Background/aims: The objective of this study was to compare the depth and width of thermal spread caused on rat uterine tissue after application of 3 different electrosurgical generators. Methods: Alsa Excell 350 MCDSe (Unit A), Meditom DT-400P (Unit M), and ERBE Erbotom VIO 300 D (Unit E) electrosurgical units (ESUs) were used. The number of Wi...

The aim of the study was to compare postoperative vaginal cuff complications due to the use of barbed sutures (V-Loc™ 180 unidirectional suture; Covidien, Mansfield, MA) and standard braided sutures (Vicryl®; Ethicon Inc., Somerville, MA) during vaginal cuff closure of patients undergoing a total laparoscopic hysterectomy (TLH) due to benign diseas...

Endometriosis is classically defined as a chronic, recurrent and progressive disease. It is known to be estrogen-dependent, but can still be observed during the peri- and postmenopausal periods. Medical management of endometriosis is palliative symptomatic relief. Surgery when properly and timely performed for the right person may treat endometrios...

Objective: Postpartum hemorrhage is still the most significant cause of maternal mortality and morbidity worldwide. Our aim was to evaluate the effect of timing of oxytocin administration on postpartum hemorrhage incidence in parturients with low-risk for postpartum hemorrhage. Study design: A randomized controlled trial was completed on 343 wom...

Objectives: This study identified patients who would benefit from an earlier additional medical intervention and/or continuing close surveillance even if commonly used parameters indicated sufficient medical treatment to determine markers of treatment failure. Materials and methods: A retrospective analysis of patients with a preliminary diagnos...

Objectives: To assess the safety and efficacy of electrosurgical bipolar vessel sealing during vaginal hysterectomy in morbidly obese patients MATERIAL AND METHODS: A total of 105 morbidly obese patients who underwent vaginal hysterectomy due to benign gynecologic pathologies between January 2010 and April 2017 were included in the study. Patients...

In pelvic organ prolapse, the anatomical defects develop at the anterior (anterior vaginal wall), the posterior (posterior vaginal wall) and the apical (the uterus/cervix or the apex of the vagina, vaginal vault or cuff scar after hysterectomy) compartments. These defects occur in more than one compartment. Treatment of pelvic organ prolapse is com...

Study objective: To demonstrate that laparoscopic excision of the endometrial tissue of a blind endometrial cavity in a patient with a Robert's uterus who did not consent to hysteroscopic surgery due to her virgin state and religious beliefs was an effective alternative treatment option for progressive dismenorrhea and pelvic pain. Design: Prese...

Objective: Determining the risk factors associated with parametrial involvement (PMI) is of paramount importance to decrease the multimodality treatment in early-stage cervical cancer. We investigated the preoperatively assessable clinical and pathological risk factors associated with PMI in surgically treated stage IB1-IIA2 cervical cancer. Meth...

Abstract Background We aimed to test the hypothesis that the correlation of the changes in the blood Androstenedione (A4) levels to the number of selected follicles during ovulation induction with low-dose recombinant human follicle stimulating hormone (rhFSH) is as strong as the correlation to changes in the blood Estradiol (E2) levels in polycyst...

PurposeThe primary purpose of this study was to assess the influence of a systematic multidisciplinary birth preparation program on satisfaction with childbirth experience. A secondary aim was to detect factors that affect the childbirth satisfaction. Methods In this prospective study, 77 pregnant women who completed the 4-month birth preparation p...

Objective: Wide variation exists in ovarian cancer incidence rates suggesting the importance of environmental factors. Due to increasing environmental pollution, trace elements and heavy metals have drawn attention in studies defining the etiology of cancer, but scant data is available for ovarian cancer. Our aim was to compare the tissue concentr...

Purpose: The purpose of this study was to analyze retrospectively the risk factors for incisional hernia (IH) in a group of gynecological cancer patients operated with abdominal midline incisions. Methods: We retrieved retrospectively data of gynecological cancer patients with midline incisions from the clinical database of Kanuni Sultan Suleyman T...

Objectives: To determine if appendectomy as an adjunctive procedure is necessary in the surgical treatment of benign ovarian mucinous cystadenomas. Material and methods: Retrospective analysis of clinical data: in a research hospital, obstetrics and gynecology depart-ment setting, 63 cases of benign ovarian mucinous cystadenomas confirmed in the...

Objectives: To compare the 'strictly' active management protocol in women with low risk of postpartum hemorrhage using the expectant management protocol with respect to changes in hematologic parameters, uterotonics, blood transfusions, or additional interventions. Material and methods: A randomized controlled prospective trial in which 934 sing...

Unlabelled: Genital prolapse is one of the most significant problems which lowers the quality of life measures of middle and older aged women. A continuously growing number of women are being operated due to this indication. Objective: This study intends to asses the clinical outcome and the impact on quality of life of uterine sacrospinous liga...

Introduction The aim of this prospective study was to investigate the diagnostic value of the fibrinogen level, platelet (PLT) count, mean platelet volume (MPV), lymphocyte count, neutrophil/lymphocyte ratio (NLR) and C-reactive protein (CRP) level with white blood cell (WBC) and neutrophil count in acute appendicitis (AA). Methods One hundred and...

Background: Patients with end stage renal disease (ESRD) have increased inflammatory and thrombotic activity. Lacks of available data exist on pro-inflammatory and prothrombotic properties of low serum 25-OH-D3 level. We aimed to analyse the association of 25-OH vitamin D with indirect markers of inflammatory and thrombotic activity in patients on...

An extremely rare case of a “primary endometrial adenocarcinoma with signet-ring cells” is presented in this study with microscopical images of the characteristic coexistence of the tumour and intermediate precancerous areas containing signet-ring cells.

INTRODUCTION Choriocarcinoma is a rare primary germ cell tumour of the ovary composed of cyto- and syncytotrophoblast cells. Most of the choriocarcinomas are normally arising in the gestational trophoblast, gonads and, less frequently, mediastinum, pineal gland and retroperitoneum. PRESENTATION OF CASE We report a case of primary choriocarcinoma o...

We present a rare case with gossypiboma following cesarean section which led to uterine wound dehiscence. A 30-year-old woman had been submitted to an emergency cesarean section 4 months previously at another hospital. Clinical and ultrasound findings revealed a large intra-abdominal mass and diffuse peritonitis. At laparotomy, a gossypiboma causin...

To determine whether insulin resistance in nonobese polycystic ovarian syndrome (PCOS) patients is associated with a higher response to ACTH stimulation. Controlled prospective study. University hospital ambulatory care unit. Twenty nonobese PCOS syndrome patients with insulin resistance and a body mass index-matched control group of 20 nonobese PC...

To evaluate the effect of the management modality of ovarian endometriomas on ovarian response to COH (controlled ovarian hyperstimulation) and ART (assisted reproductive technology) treatment outcome. Retrospective case control study. Ege University Infertility-Family Planning Research and Treatment Center. 115 cycles of 84 patients who underwent...

To examine whether blood estradiol level tendencies during the late follicular and early luteal phases and the 11 days after embryo transfer have any association with the outcome of intracytoplasmic sperm injection-embryo transfer (ICSI-ET) cycles. This prospective study involved 38 assisted reproductive technology cycles in 35 infertile patients t...