Erling Thom

Erling Thom
ETC AS · Research and Development

Ph.D.

About

50
Publications
23,344
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2,020
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Publications

Publications (50)
Article
Full-text available
Follicular proteoglycans are key players with structural, functional, and regulatory roles in the growth and cycling behaviour of the hair follicles. The expression pattern of specific proteoglycans is strongly correlated with follicular phase transitions, which further affirms their functional involvement. Research shows that bioactive proteoglyca...
Article
Full-text available
TREATING FEMALE DIFFUSE HAIR LOSS
Article
Postpartum effluvium is a well-known clinical fact. However, following some minor research activities in the 1960s, very little has happened on the research front of the subject. It was hypothesized that postpartum hair loss might be a manifestation of a change in the hair growth cycle occurring normally during pregnancy. Recently, new research has...
Article
Full-text available
The stress hormone, cortisol, is known to affect the function and cyclic regulation of the hair follicle. When cortisol is present at high levels it has been demonstrated to reduce the synthesis and accelerate the degradation of important skin elements, namely hyaluronan and proteoglycans by approximately 40%. The following discussion outlines the...
Article
Long-term treatment of psoriasis can be a challenge, mainly due to the tolerability problems with the potent corticoids used. Atrophy is a frequent problem in this respect. Intermittent treatment with other topical substances following the active drug period is therefore often used. The liver oil from ratfish (Chimaera Monstrosa) contains alkoxygly...
Article
Background: Topical use of strontium (Sr) has been reported to have anti-itching, anti-irritant and pain relieving properties. The probable mechanism of action is that strontium has the ability to block or inhibit the intact C-nociceptors as well as Ao- nociceptors from firing The purpose of the present study was to investigate the effect of a stro...
Article
Full-text available
The results from a clinical study performed in 12 healthy volunteers with different coffee products containing glucose show that instant coffee enriched with chlorogenic acid induced a reduction in the absorption of glucose of 6.9% compared with the control. No such effects were seen with normal or decaffeinated instant coffee. In a second, compara...
Article
This randomized, double-blind, placebo-controlled study was designed to investigate the efficacy and tolerability of Nourkrin, a new natural agent for the treatment of hair loss based on marine proteins, and minerals and vitamins. Fifty-five subjects with hair loss of different aetiologies participated in the 6-month blinded phase of the study. Obj...
Article
In this double-blind, placebo-controlled study, 40 women with ageing symptoms of the skin were randomized to receive DermaVite, a new preparation containing marine proteins, alpha-lipoic acid, pine bark extract, vitamins and minerals (n = 20), or placebo (n = 20) twice daily for 6 months. Objective measurements of skin thickness and elasticity, tog...
Article
Full-text available
Fiber supplements added to a caloric diet have additional effects on weight reduction in overweight subjects. The aim of this study was to compare the effect of various commercial fiber supplements (glucomannan, guar gum and alginate) on weight reduction in healthy overweight subjects. One hundred and seventy six men and women were included to rece...
Article
Throat infections are common conditions in general practice. Pain and discomfort can be considerable in all kinds of throat infections and it would be of great clinical relevance to find out if either of the two types of colostrum tablets sold over the counter in Norway shortens the duration of symptoms in throat infections not caused by group A st...
Article
Full-text available
Elderberry has been used in folk medicine for centuries to treat influenza, colds and sinusitis, and has been reported to have antiviral activity against influenza and herpes simplex. We investigated the efficacy and safety of oral elderberry syrup for treating influenza A and B infections. Sixty patients (aged 18-54 years) suffering from influenza...
Article
A new gel containing Conjugated Linoleic Acid (CLA) used in adult patients with chronic stable psoriasis vulgaris, showed promising therapeutic results. The duration of the study was 4 weeks. Forty patients were included; 20 received in a randomised manner treatment with the new gel and 20 got placebo. The study was carried out as a double blind tr...
Article
Full-text available
This study was designed to investigate the efficacy and tolerability of daily conjugated linoleic acid (CLA) in healthy exercising humans. This was a random-double-blind, placebo-controlled study in 20 healthy humans of normal body weight and body mass index less than 25.0 kg/m2, who did standardized physical exercise in a gym for 90 min three time...
Article
Full-text available
This randomized, placebo-controlled, double-blind study was designed to investigate the efficacy and tolerability of a new agent for the treatment of hair loss, based on a marine protein, minerals and vitamins. Sixty subjects with hair loss of different aetiologies participated in the 6-month blinded phase of the study. Objective assessments indica...
Article
The present open pilot study was carried out in order to investigate a new patented concept for skin treatment. The new concept is intended for use in treatment of ageing skin. The ointment contains conjugated linoleic acid (CLA) and retinyl palmitate (RP). Both ingredients are conjugated with the biopolymer chitosan in order to improve water solub...
Article
Conjugated linoleic acid (CLA) has been shown to reduce body fat mass (BFM) in animals. To investigate the dose-response relationships of conjugated linoleic acid with regard to BFM in humans, a randomized, double-blind study including 60 overweight or obese volunteers (body mass index 25-35 kg/m(2)) was performed. The subjects were divided into fi...
Article
Full-text available
The efficacy and tolerability of a new weight-reduction agent, based on natural ingredients, was investigated in this randomized, placebo-controlled, double-blind study. The product reduces the absorption of different types of sugar from the gastrointestinal tract. Forty obese volunteers were included in the 12-week study. Body weight, body composi...
Article
The main objective of the study was to investigate the safety of conjugated linoleic acid (CLA) in healthy volunteers. The effect of CLA on body composition was also investigated.The trial design was a randomized, double-blind placebo controlled study including 60 overweight or obese volunteers (body mass index (BMI) 27.5—39.0 kg/m2). The subjects...
Article
The aim of the study was to investigate the long term effect of diet, exercise and intermittent treatment of cimetidine on body weight and maintenance of weight lost during treatment. Fifty women and five men who had completed a 8 week randomized double-blind, placebo-controlled trial of cimetidine for weight loss were invited to participate in an...
Article
The present placebo controlled double blind study was carded out in 59 non smoking females with aging symptoms of the skin. Skingain®, a new preparation, containing marine proteins, vitamins and minerals, was given twice daily to 29 persons, and an identical placebo capsule was given twice daily to 30 persons in a randomised way. The study had a du...
Article
A randomized comparative double-blind vehicle controlled study of a topical treatment of fat deposits and cellulitis on the thighs. The active treatment caused a significant reduction in fat deposits and cellulitis in a population of 25 females during a treatment period of 6 weeks as compared to the vehicle treatment. The efficacy of the treatment...
Article
In two Norwegian industrial companies 42 employees (24 female/18 male) with shoulder, neck and back problems took part in a training programme for a period of 12 months. The programme comprised of daily relaxation exercises at work combined with training at home three times a week for about 30 minutes on each occasion. The physical therapy and trai...
Article
The study was carried out as an open, randomized, multicenter, parallel-group study with an observation period of 12 months. Four norwegian physiotherapy institutes took part. Patients were subsequently followed for 12 months of home exercise on their own, without for 12 months of home exercise on their own, without the supervision of a physiothera...
Article
Study Design. The study was carried out as an open, randomized, multicenter, parallel‐group study with an observation period of 12 months. Four Norwegian physiotherapy institutes took part. Patients were subsequently followed for 12 months of home exercise on their own, without the supervision of a physiotherapist. Objectives. 1) To investigate and...
Article
A randomized, double-blind placebo-controlled parallel group clinical trial was performed to investigate the therapeutic effect of Kanjang mixture in the treatment of uncomplicated upper respiratory tract infections (common cold). Sixty-six patients aged between 18 and 40 years participated. Medication was taken three times daily for a minimum of 5...
Article
Full-text available
A commercial product, Libido (Libid, Libbido, Erosom and Ardorare, names used in different markets), which is based on components derived from fertilized, partly incubated chickens' eggs, has been used to treat diminished sexual desire in men. The results from two double-blind cross-over placebo-controlled experiments indicate that Libido has a sig...
Article
The aim of this study was to investigate the relationship between the blood pressure response and body fat in patients treated with the calcium entry blocker nifedipine. Forty untreated subjects with moderate hypertension completed the study. Height, weight, body mass index (BMI) and body fat (measured by near infrared spectrophotometry using Futre...
Article
A randomised double-blind within subject study comparing two galenical formulations of retinyl palmitate (RP), a conjugated and an unconjugated one, showed significant differences in favour of the conjugated formulation with respect to improvement in objective and subjective skin parameters on the volar part of the forearms. The treatment period wa...
Article
The quality of weight loss was estimated during a very low calorie diet (VLCD) weight-reducing regime by determining the body composition every second week using near-infra-red interactance (NII). The study was performed on 127 overweight volunteers, aged 18-72 years, who, for eight consecutive weeks, used a VLCD to lose weight. Mean weight reducti...
Article
The present study includes 413 persons with overweight or obesity problems, with Body Mass Index (BMI) ranging from 26.7 to 40.2 kg/m2, who participated in a seven weeks weight reduction programme. All persons were given the opportunity either to follow a low-fat diet (1,200 kcal/d) alone or a low-fat diet combined with an exercise programme (1/2 h...
Article
A randomized comparative double-blind within subject study of topical administration of two different galenical formulations of retinyl palmitate (RP) α 2% W/W for 3 months in 20 females, caused significant changes in skin thickness and elasticity as well as in the persons self-evaluations of skin improvements following administration of a polysacc...
Article
One hundred and seventy-four patients suffering from restless legs were included in a double-blind trial. Eighty-four patients were treated with carbamazepine (CBZ) and 90 with placebo. Discrimination analysis was carried out in order to characterize the patients who did not benefit from the treatment. Patients treated with CBZ were divided into re...
Article
The clinical efficacy of hydralazine, either as Apresoline® or Apresoline® SR given once daily in combination with other antihypertensive treatment was studied in 47 hypertensive out-patients. The study design was double-blind, randomized, between-patients. The hydralazine dose was at the start 50 mg o.d. and increased to 100 or 150 mg if adequate...
Article
The increases in medan scoresfluence on gastroduodenal mucosa of naproxen, 500 mg/day, and diclofenac, 100 mg/day, for 1 wk was investigated in 14 subjects in a double-blind randomized crossover study. Endoscopic examination of the gastroduodenal mucosa was carried out before and after each drug with regard to gastritis and hemorrhagic and erosive...

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