Erin Dicaprio

Erin Dicaprio
University of California, Davis | UCD · Department of Food Science and Technology

M.S., Ph.D.

Publications

Publications (29)
Article
An increasing number of hepatitis E virus (HEV) infections in industrialized countries have been foodborne and linked to the consumption of undercooked pork products. To date, data on the prevalence of HEV in pork products sold in the United States is limited and no standard processing method exists for the detection of HEV in foods. In order to de...
Article
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Human norovirus (NoV) is a major cause of fresh produce associated outbreaks. In this study a non-thermal process, high pressure processing (HPP), was evaluated for efficacy against a human NoV GII.4 strain, and Tulane virus (TV). Virus survival following HPP treatment was determined using direct quantitative reverse transcriptase PCR (RT-qPCR), th...
Article
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Hepatitis E Virus (HEV) is endemic in areas with poor sanitation and has traditionally been classified as a water-borne virus. Until recently, cases of HEV in industrialized countries were associated with travel to those areas. In the last decade, locally acquired cases of HEV have increased in the European Union, leading to the investigation of po...
Article
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Although transmission of human norovirus in food establishments is commonly attributed to consumption of contaminated food, transmission via contaminated environmental surfaces, such as those in bathrooms, may also play a role. Our aim was to determine the prevalence of human norovirus on bathroom surfaces in commercial food establishments in New J...
Article
Human norovirus is a leading cause of foodborne illness worldwide. For years, the detection of the virus in foods and determining its inactivation during food processing have been challenging. Recently, there have been promising advances in human norovirus cultivation and several innovative approaches have been developed as in vitro methods to esti...
Article
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Autophagy is an essential component of host immunity and utilized by viruses for survival. However, the autophagy signaling pathways involved in virus replication are poorly documented. Here, we observed that rabies virus (RABV) infection triggered intracellular autophagosome accumulation and results in incomplete autophagy by inhibiting autophagy...
Article
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Importance: Human norovirus (HuNoV) is a leading cause of foodborne disease worldwide. Noroviruses are highly diverse, both antigenically and genetically. Genogroup II (GII) contains the majority of HuNoV, with genotype 4 (GII.4) being the most prevalent. Recently, GII.1 and GII.6 have emerged and caused many outbreaks worldwide. However, the surv...
Article
Human norovirus (NoV) is a major cause of fresh produce-associated outbreaks and human NoV in irrigation water can potentially lead to viral internalization in fresh produce. Therefore, there is a need to develop novel intervention strategies to target internalized viral pathogens while maintaining fresh produce quality. In this study electron beam...
Article
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Human enteric viruses are one of the main causative agents of shellfish associated outbreaks. In this study, the kinetics of viral bioaccumulation in live oysters and the heat stability of the most predominant enteric viruses were determined in both tissue culture and in oyster tissues. A human norovirus (HuNoV) GII.4 strain, HuNoV surrogates [muri...
Article
Acute gastroenteritis caused by human norovirus is a significant public health issue. Fresh produce and seafood are examples of high-risk foods associated with norovirus outbreaks. Food contact surfaces also have the potential to harbor noroviruses if exposed to fecal contamination, aerosolized vomitus, or infected food handlers. Currently, there i...
Article
Rotavirus (RV) is the major etiological agent of acute gastroenteritis in infants worldwide. Although high pressure processing (HPP) is a popular method to inactivate enteric pathogens in food, the sensitivity of different virus strains within same species and serotype to HPP is variable. This study aimed to compare the baro-sensitivity of seven RV...
Article
Full-text available
Human norovirus (NoV) is responsible for over 90% of outbreaks of acute nonbacterial gastroenteritis worldwide and accounts for 60% of foodborne illness in the US. Currently, the infectivity of human NoVs is poorly understood due to the lack of a cell culture system. In this study, we determined the survival of a human NoV GII.4 strain in seeded oy...
Article
Human norovirus (NoV) is the major causative agent of fresh produce related outbreaks of gastroenteritis; however the ecology and persistence of human NoV in produce systems is poorly understood. In this study, the effects of abiotic and biotic stress on viral internalization and dissemination of two human NoV surrogates (murine norovirus [MNV-1] a...
Article
Full-text available
Human norovirus (NoV) is the leading cause of foodborne disease in the U.S. and epidemiological studies have shown that fresh produce is one of the major vehicles for the transmission of human NoV. However, the mechanisms of norovirus contamination and persistence in fresh produce are poorly understood. The objective of this study is to determine w...
Article
Human norovirus (NoV) is the number one cause of foodborne illness. Despite tremendous research efforts, human NoV is still poorly understood and understudied. There is no effective measure to eliminate this virus from food and the environment. Future research efforts should focus on developing: (1) an efficient cell culture system and a robust ani...
Article
Full-text available
Fresh produce is a major vehicle for the transmission of human norovirus (NoV) because it is easily contaminated during both pre- and postharvest stages. However, the ecology of human NoV in fresh produce is poorly understood. In this study, we determined whether human NoV and its surrogates can be internalized via roots and disseminated to edible...
Article
Human norovirus (HuNoV) is the leading causative agent of foodborne disease outbreaks worldwide. HuNoV is highly stable, contagious, and only a few virus particles can cause illness. However, HuNoV is difficult to study because of the lack of an efficient in vitro cell culture system or a small animal model. To date, there is very limited informati...
Article
Full-text available
Gamma irradiation is a nonthermal processing technology that has been used for the preservation of a variety of food products. This technology has been shown to effectively inactivate bacterial pathogens. Currently, the FDA has approved doses of up to 4.0 kGy to control food-borne pathogens in fresh iceberg lettuce and spinach. However, whether thi...
Data
Reduced tail strength of mice receiving an adoptive transfer of MPS IIIB mouse lymphocytes. Splenic lymphocytes (2 × 107) from MPS IIIB mice were injected IV into wt littermates. Video of a MPS IIIB lymphocyte recipient mouse was taken at 2 wk post transfer, showing the decrease in tail strength, compared with the mice treated with wt lymphocytes (...
Data
Reduced tail strength of mice receiving an adoptive transfer of MPS IIIB mouse lymphocytes. Splenic lymphocytes (2 × 107) from MPS IIIB mice were injected IV into wt littermates. Video of a MPS IIIB lymphocyte recipient mouse was taken at 2 wk post transfer, showing the decrease in tail strength, compared with the mice treated with wt lymphocytes (...
Data
Tail strength of mice receiving an adoptive transfer of wt mouse lymphocytes. Splenic lymphocytes (2 × 107) from wt mice were injected IV into wt littermates. Video of a wt lymphocyte recipient mouse was taken at 2 wk post transfer, showing the tail strength, as a control of MPS IIIB lymphocyte recipient mice (Additional files 1 &2).
Data
Tail strength of mice receiving an adoptive transfer of wt mouse lymphocytes. Splenic lymphocytes (2 × 107) from wt mice were injected IV into wt littermates. Video of a wt lymphocyte recipient mouse was taken at 2 wk post transfer, showing the tail strength, as a control of MPS IIIB lymphocyte recipient mice (Additional files 1 &2).
Article
Full-text available
Recently, using a mouse model of mucopolysaccharidosis (MPS) IIIB, a lysosomal storage disease with severe neurological deterioration, we showed that MPS IIIB neuropathology is accompanied by a robust neuroinflammatory response of unknown consequence. This study was to assess whether MPS IIIB lymphocytes are pathogenic. Lymphocytes from MPS IIIB mi...
Article
Mucopolysaccharidosis (MPS) IIIB is a lysosomal storage disease with severe neurological manifestations due to alpha-N-acetylglucosaminidase (NaGlu) deficiency. The mechanism of neuropathology in MPS IIIB is unclear. This study investigates the role of immune responses in neurological disease of MPS IIIB in mice. By means of gene expression microar...

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