Eric Rawson

Eric Rawson
Messiah University · Department of Health, Nutrition, and Exercise Science

Doctor of Philosophy

About

84
Publications
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Publications

Publications (84)
Article
Full-text available
It is well-established that creatine supplementation augments the gains in muscle mass and performance during periods of resistance training. However, whether the timing of creatine ingestion influences these physical and physiological adaptations is unclear. Muscle contractions increase blood flow and possibly creatine transport kinetics which has...
Article
Full-text available
The immune function is closely related to iron (Fe) homeostasis and allostasis. The aim of this bioinformatics-assisted review was twofold; (i) to update the current knowledge of Fe metabolism and its relationship to the immune system, and (ii) to perform a prediction analysis of regulatory network hubs that might serve as potential biomarkers duri...
Article
Full-text available
While the vast majority of research involving creatine supplementation has focused on skeletal muscle, there is a small body of accumulating research that has focused on creatine and the brain. Preliminary studies indicate that creatine supplementation (and guanidinoacetic acid; GAA) has the ability to increase brain creatine content in humans. Fur...
Article
Purpose The safety of creatine supplementation has been investigated, however, the safety of a high-dose/short-term or low-dose/long-term supplementation dosing scheme, combined with a resistance training program, a commonly used dosing scheme, has not yet studied. The aim of this study was to evaluate physical performance and the safety of the cit...
Article
Full-text available
Supplementing with creatine is very popular amongst athletes and exercising individuals for improving muscle mass, performance and recovery. Accumulating evidence also suggests that creatine supplementation produces a variety of beneficial effects in older and patient populations. Furthermore, evidence-based research shows that creatine supplementa...
Article
Full-text available
Creatine (Cr) and phosphocreatine (PCr) are physiologically essential molecules for life, given they serve as rapid and localized support of energy- and mechanical-dependent processes. This evolutionary advantage is based on the action of creatine kinase (CK) isozymes that connect places of ATP synthesis with sites of ATP consumption (the CK/PCr sy...
Article
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Numerous health conditions affecting the musculoskeletal, cardiopulmonary, and nervous systems can result in physical dysfunction, impaired performance, muscle weakness, and disuse-induced atrophy. Due to its well-documented anabolic potential, creatine monohydrate has been investigated as a supplemental agent to mitigate the loss of muscle mass an...
Article
Full-text available
Creatine (Cr) is a ubiquitous molecule that is synthesized mainly in the liver, kidneys, and pancreas. Most of the Cr pool is found in tissues with high-energy demands. Cr enters target cells through a specific symporter called Na+/Cl−-dependent Cr transporter (CRT). Once within cells, creatine kinase (CK) catalyzes the reversible transphosphorylat...
Article
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There is a robust and compelling body of evidence supporting the ergogenic and therapeutic role of creatine supplementation in muscle. Beyond these well-described effects and mechanisms, there is literature to suggest that creatine may also be beneficial to brain health (e.g., cognitive processing, brain function, and recovery from trauma). This is...
Article
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The ergogenic and therapeutic effects of increasing muscle creatine by supplementation are well-recognized. It appears that similar benefits to brain function and cognitive processing may also be achieved with creatine supplementation, however research in this area is more limited, and important knowledge gaps remain. The purpose of this review is...
Article
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Nutrition usually makes a small but potentially valuable contribution to successful performance in elite athletes, and dietary supplements can make a minor contribution to this nutrition program. Nonetheless, supplement use is widespread at all levels of sport. Products described as supplements target different issues, including the management of m...
Article
Full-text available
Nutrition usually makes a small but potentially valuable contribution to successful performance in elite athletes, and dietary supplements can make a minor contribution to this nutrition programme. Nonetheless, supplement use is widespread at all levels of sport. Products described as supplements target different issues, including (1) the managemen...
Article
Some dietary supplements are recommended to athletes based on data that supports improved exercise performance. Other dietary supplements are not ergogenic per se, but may improve health, adaptation to exercise, or recovery from injury, and so could help athletes to train and/or compete more effectively. In this review, we describe several dietary...
Article
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Team sport athletes face a variety of nutritional challenges related to recovery during the competitive season. The purpose of this article is to review nutrition strategies related to muscle regeneration, glycogen restoration, fatigue, physical and immune health, and preparation for subsequent training bouts and competitions. Given the limited opp...
Article
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Exertional (exercise-induced) rhabdomyolysis is a potentially life threatening condition that has been the subject of research, intense discussion, and media attention. The causes of rhabdomyolysis are numerous and can include direct muscle injury, unaccustomed exercise, ischemia, extreme temperatures, electrolyte abnormalities, endocrinologic cond...
Article
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This narrative review aims to summarize the recent findings on the adjuvant application of creatine supplementation in the management of age-related deficits in skeletal muscle, bone and brain metabolism in older individuals. Most studies suggest that creatine supplementation can improve lean mass and muscle function in older populations. Important...
Article
Full-text available
The purpose of this study was to examine the impact of body composition on energy expenditure (EE) of 164 young adults during a 1-mile walk and a 1-mile run on a treadmill. Segmental bioimpedance was used to measure body composition variables. The EE in men (108.3 ± 17.6 kcal) was greater than (P < 0.05) women (80.3 ± 10.6 kcal) during the 1-mile w...
Article
Although dietary supplements offer consumers the ability to participate in their own health and well being, steps need to be taken to educate the public and clinicians to prevent misuse and encourage proper use. Better patient education through health care providers and the establishment of good manufacturing procedures for supplement producers wil...
Chapter
While the specific nutritional requirements of the strength and power athlete are no doubt sport and athlete-specific, these athletes do have similar overall objectives when it comes to dietary needs: (i) maintain good health, (ii) provide energy for training and competition, (iii) support recovery and adaptation from training and competition, and...
Article
We examined the impact that cycle ergometry exercise had on percent body fat (% BF) estimates when assessed using either leg-to-leg or segmental bioelectrical impedance analysis (LBIA; SBIA) and whether the intensity of the exercise bout impacts the %BF magnitude of change. Seventy-four college-aged adults participated in this study. Participants v...
Article
Fifteen young adult males participated in leg and arm ergometry with CO measured throughout incremental workloads. No significant difference exists for COabs (L·min-1) during leg ergometry between larger (14.34±4.93) and smaller (12.68±4.47) leg musculatures (P=0.067). During arm exercise, COabs was greater in participants with larger (20.25±9.60)...
Article
Recently, it was demonstrated that a uniaxial accelerometer worn at the hip could estimate resistance exercise energy expenditure. As resistance exercise takes place in more than 1 plane, the use of a triaxial accelerometer may be more effective in estimating resistance exercise energy expenditure. The aims of this study were to estimate the energy...
Article
There is an extensive and still growing body of the literature supporting the efficacy of creatine (Cr) supplementation. In sports, creatine has been recognized as the most effective nutritional supplement in enhancing exercise tolerance, muscle strength and lean body mass. From a clinical perspective, the application of Cr supplementation is indee...
Article
This is a retrospective and descriptive analysis of demographic and clinical factors common among cardiac rehabilitation patients with high versus low perceptions of health-related quality of life(HRQOL). In addition, we describe the characteristics that are predictive of greater improvements in HRQOL during cardiac rehabilitation. We included 970...
Article
We examined the effects of 6 wk of low-dose creatine supplementation on body composition, muscle function, and body creatine retention. Twenty healthy men and women (21 ± 2 y old) were randomized to receive creatine (0.03 g · kg(-1) · d(-1); n = 10, 4 women) or placebo (n = 10, 4 women) for 6 wk in a double-blind placebo-controlled fashion. Partici...
Article
The ingestion of the dietary supplement creatine (about 20 g/day for 5 days or about 2 g/day for 30 days) results in increased skeletal muscle creatine and phosphocreatine. Subsequently, the performance of high-intensity exercise tasks, which rely heavily on the creatine-phosphocreatine energy system, is enhanced. The well documented benefits of cr...
Article
Those who are old enough to have been working in the world of sports science/medicine in 1992 will remember a watershed moment: the publication of a paper by Roger Harris and co-workers(1) on the capacity of the muscle to increase its phosphocreatine concentration following supplementation with a creatine product. With the genie out of the bottle,...
Article
Aging is associated with decreased muscle function and cognitive processing. Current pharmacological and nutritional therapies to slow the progression of or reverse these effects have been unremarkable. Creatine is a natural component of the diet, and, as a dietary supplement, enhances fatigue resistance, increases strength, improves the performanc...
Article
Weight loss and muscle gain are physique goals pursued by many athletes, often with the hope that both will occur simultaneously! Part 9 of our series on dietary supplements includes summaries of three products which address these interests among other claimed benefits: choline bitartrate, chromium picolinate and cissus quandrangularis (CQ). Cholin...
Article
STEC, M. J.; RAWSON, E. S. Benefits of creatine supplementation for older adults. Brazilian Journal of Biomotricity, v. 4, n. 4, p. 215-226, 2010. Decreases in muscle mass (i.e. sarcopenia), strength, and power due to the aging process can result in an impaired ability to perform daily tasks and ultimately lead to functional disability in older adu...
Article
Resistance exercise is recommended by the major health and sports medicine organizations to maintain good health, but resistance exercise energy expenditure is difficult to measure. Accelerometers offer a viable alternative to estimate energy expenditure during resistance exercise because they are cost effective and do not restrict motion or exerci...
Article
Reportedly, muscle fatigue in older individuals is greater, less than, or similar to young individuals, potentially because of differences in muscle groups studied, type of contraction, continuous vs. intermittent contractions, exercise duration, duty cycle, and contraction speed. During a single set of isokinetic mode knee extensions, muscle fatig...
Article
Full-text available
Cross-sectional studies have reported seasonal variation in high-sensitivity C-reactive protein (hsCRP). However, longitudinal data are lacking. We collected data on diet, physical activity, psychosocial factors, physiology, and anthropometric measurements from 534 healthy adults (mean age 48 years, 48.5% women, 87% white) at quarterly intervals ov...
Article
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Creatine supplementation has been reported to improve certain aspects of cognitive and psychomotor function in older individuals and in young subjects following 24 and 36 h of sleep deprivation. However, the effects of creatine supplementation on cognitive processing and psychomotor performance in non-sleep deprived young adults have not been asses...
Chapter
CreatineCentral Nervous System StimulantsAnabolic-Androgenic SteroidsConclusions AcknowledgmentReferences
Article
Previous studies have shown that creatine supplementation reduces muscle damage and inflammation following running but not following high-force, eccentric exercise. Although the mechanical strain placed on muscle fibers during high-force, eccentric exercise may be too overwhelming for creatine to exert any protective effect, creatine supplementatio...
Article
Full-text available
Creatine supplementation is a widely used and heavily studied ergogenic aid. Athletes use creatine to increase muscle mass, strength, and muscle endurance. While the performance and muscle- building effects of creatine supplementation have been well documented, the mechanisms responsible for these muscular adaptations have been less studied. Object...
Article
Full-text available
The literature on creatine supplementation supporting its efficacy has grown rapidly and has included studies in both healthy volunteers and patient populations. However, the first rule in the development of therapeutic agents is safety. Creatine is well-tolerated in most individuals in short-term studies. However, isolated reports suggest creatine...
Article
A large number of studies have been published on creatine supplementation over the last decade. Many studies show that creatine supplementation in conjunction with resistance training augments gains in muscle strength and size. The underlying physiological mechanism(s) to explain this ergogenic effect remain unclear. Increases in muscle fiber hyper...
Article
The purpose of this case study was to examine the effects of repeated creatine administration on muscle phosphocreatine, plasma creatine, and urine creatine. One male subject (age, 32 years; body mass, 78.4 kg; height, 160 cm; resistance training experience, 15 years) ingested creatine (20 g.d(-1) for 5 days) during 2 bouts separated by a 30-day wa...
Article
Creatine monohydrate has become the supplement of choice for many athletes striving to improve sports performance. Recent data indicate that athletes may not be using creatine as a sports performance booster per se but instead use creatine chronically as a training aid to augment intense resistance training workouts. Although several studies have e...
Article
Elevated high-sensitivity c-reactive protein (hs-CRP) is associated with increased risk of future first and recurrent coronary events and has been associated with both high body mass index (BMI) and low physical activity in cross sectional studies. To longitudinally examine the effects of BMI and both current and previous-year physical activity on...
Article
The Trp64Arg polymorphism in the beta(3)-adrenoceptor gene has been associated with increased prevalence of obesity, type 2 diabetes, and low rates of energy expenditure, although these findings are not unanimous. It is currently unknown if the presence of the Trp64Arg gene variant impedes the loss of body weight in obese, postmenopausal women via...
Article
This study compared the effects of short-term creatine supplementation on muscle phosphocreatine, blood and urine creatine levels, and urine creatinine levels in elderly and young subjects. Eight young (24 +/- 1.4 years) and seven old (70 +/- 2.9 years) men ingested creatine (20 g day-1) for 5 days. Baseline muscle phosphocreatine measurements were...
Article
This investigation evaluated the effects of oral creatine (Cr) supplementation on markers of exercise-induced muscle damage following high-force eccentric exercise in subjects randomly administered Cr or placebo (P) in a double-blind fashion. When injected, exogenous phosphocreatine has been shown to stabilize the muscle membrane in cardiac tissue...
Article
The hypothesis of this study was that short term creatine (Cr) ingestion in older individuals would increase body mass and exercise performance, as has been shown in younger subjects. Seventeen males 60-78 years old were randomly placed into two groups, Cr and placebo (P), and supplemented in double-blind fashion for 5 days. Subjects ingested eithe...
Article
Although nutritional supplements purported to increase muscle mass are widely available at health food stores, gyms, by mail order, and over the Internet, many of these supplements have little or no data to support their claims. This article reviews the theory and research behind popular nutritional supplements commonly marketed as muscle mass buil...
Article
In this investigation we evaluated the effects of oral creatine (Cr) supplementation on body composition, strength of the elbow flexors, and fatigue of the knee extensors in 20 males aged 60-82 years who were randomly administered Cr or placebo (P) in a double-blind fashion. Subjects ingested either 20 g of Cr or P for 10 days, followed by either 4...
Article
Aging results in decreased muscle mass (i.e. sarcopenia), decreased muscle strength, and decreased ability to perform daily tasks. Creatine supplementation has been shown to increase lean body mass and muscle strength, and reduce muscle fatigue in young individuals. The beneficial effects of creatine previously demonstrated in younger subjects woul...