Erasmus Kotey

Erasmus Kotey
Noguchi Memorial Institute for Medical Research | NMIMR · Virology

About

7
Publications
973
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20
Citations

Publications

Publications (7)
Article
Full-text available
Introduction: Avian influenza viruses (AIV) cause significant economic losses to poultry farmers worldwide. These viruses have the ability to spread rapidly, infect entire poultry flocks, and can pose a threat to human health. The National Influenza Centre (NIC) at the Noguchi Memorial Institute for Medical Research in collaboration with the Ghana...
Article
Full-text available
Identification of a universal influenza vaccine candidate has remained a global challenge for both humans and animals. This study describes an approach that uses consensus sequence building to generate chimeric HAs (cHAs): two resultant H1 HA-based chimeras comprising of conserved sequences (within several areas spanning the head and stalk regions)...
Article
Full-text available
Background: A novel coronavirus, SARS-CoV-2 is currently causing a worldwide pandemic. The first cases of SARS-CoV-2 infection were recorded in Ghana on March 12, 2020. Since then, the country has been combatting countrywide community spread. This report describes how the Virology Department, Noguchi Memorial Institute for Medical Research (NMIMR)...
Article
Full-text available
The confirmed case fatality rate for the coronavirus disease 2019 (COVID-19) in Ghana has dropped from a peak of 2% in March to be consistently below 1% since May 2020. Globally, case fatality rates have been linked to the strains/clades of circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within a specific country. Here we p...
Article
Full-text available
Background: Viral hemorrhagic fevers (VHFs) are infectious illnesses that can cause serious morbidity and mortality to infected persons. During the 2014 Ebola virus disease outbreak in some West African countries, Ghana revamped its surveillance system across the country to prepare, effectively respond and pre-empt any public health concerns Object...
Article
Full-text available
Influenza is a disease that poses a significant health burden worldwide. Vaccination is the best way to prevent influenza virus infections. However, conventional vaccines are only effective for a short period of time due to the propensity of influenza viruses to undergo antigenic drift and antigenic shift. The efficacy of these vaccines is uncertai...
Preprint
Influenza is a disease that poses a significant health burden worldwide. Vaccination is the best way to prevent influenza virus infections. However, conventional vaccines are only effective for a short period of time due to the propensity of influenza viruses to undergo antigenic drift and antigenic shift. The efficacy of these vaccines is uncertai...

Questions

Question (1)
Question
Trying to switch from expressing proteins in the S2 cells to using the C6/ 36 cells...
Kindly let me know also if the C6/ 36 cells are amenable to protein expression.
Note: Expression plasmid is under the insect P-actin promoter.

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