Enrico Camporesi

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Verified

Enrico verified their affiliation via an institutional email.

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• MD
• Emeritus Professor at University of South Florida

Background and Objectives: Extracorporeal membrane oxygenation (ECMO) can support patients with severe cardiopulmonary failure, but it poses risks such as hemolysis, leading to complications. Plasma-free hemoglobin (PFH) is a hemolysis biomarker, with elevated levels linked to mortality. This study evaluates PFH and ECMO survival in COVID-19, non-C...

Background and objective Concussion can lead to complex physiologic changes, including alterations to cerebral blow flow autoregulation. Based on this understanding, we aimed to analyze if concussed patients undergoing orthopedic surgery required a higher dosage or a more frequent administration of phenylephrine while under general anesthesia; we a...

Background: Patients with obesity, especially those suffering from obstructive sleep apnea (OSA), are prone to postoperative respiratory hypoxemia. The PRODIGY (prediction of opioid-induced respiratory depression in patients monitored by capnography) Score is used to predict respiratory complications that factor in sleep-disordered breathing. Data...

Released in February 2025 Hyperbaric Medicine Practice 5th Edition https://lnkd.in/e3EBcRfq Split into two volumes due to its size and detail, this 5th edition boasts six new chapters. With the help of 70 contributors from all over the world, Hyperbaric Medicine Practice has become the go-to authority for both studying and practicing hyperbaric me...

Objectives Complex regional pain syndrome remains a challenging condition characterized by severe, persistent pain and a variety of inflammatory and trophic symptoms. This study aimed to analyze the current literature to evaluate hyperbaric oxygen therapy (HBOT)’s efficacy in treating complex regional pain syndrome (CRPS), focusing on both sympathe...

Hyperbaric oxygen therapy (HBOT) is a non-invasive method of O2 delivery that induces systemic hyperoxia. Hyperbaric chamber consists of a pressure vessel and a compressed breathing gas supply, which can regulate internal pressure. The chamber delivers 100% O2 to patients according to predetermined protocols and is monitored by trained personnel. H...

Hyperbaric oxygen therapy (HBOT) is a non-invasive method of O2 delivery that induces systemic hyperoxia. Hyperbaric chamber consists of a pressure vessel and a compressed breathing gas supply, which can regulate internal pressure. The chamber delivers 100% O2 to patients according to predetermined protocols and is monitored by trained personnel. H...

Heart failure is characterized by the heart’s inadequate pumping capacity, leading to significant morbidity and mortality rates.

Background Current diving physiology postulates that SCUBA divers’ arterial blood gas (ABG) levels vary proportionally to environmental pressure, but, to date, ABGs have only been obtained during simulated dives. Also, recent evidence supports the use of the arterial/alveolar (a:A) partial pressures of oxygen (PO2) ratio to predict the arterial PO2...

Underwater activities are characterized by an imbalance between reactive oxygen/nitrogen species (RONS) and antioxidant mechanisms, which can be associated with an inflammatory response, depending on O2 availability. This review explores the oxidative stress mechanisms and related inflammation status (Oxy-Inflammation) in underwater activities such...

Possible opportunities of intervention with Hyperbaric Oxygen Therapy (HBO2) when it comes to Avascular Necrosis (Aseptic Osteonecrosis).

EPAP masks have been found to be effective in patients with snoring and obstructive sleep apnea and are FDA cleared for such purpose. EPAP masks are not always effective, but the reason for lack of effectiveness in some patients is not well understood. EPAP masks offer different levels of expiratory resistance, but it is not clear if such differenc...

Long COVID-19 patients show systemic inflammation and persistent symptoms such as fatigue and malaise, profoundly affecting their quality of life. Since improving oxygenation can oppose inflammation at multiple tissue levels, we hypothesized that hyperbaric oxygen therapy (HBOT) could arrest inflammation progression and thus relieve symptoms of COV...

Introduction: Patients receiving bariatric surgery are at risk for sleep apnea (OSA) and need extensive surveillance in the postoperative period. There is evidence of respiratory events (RE) several hours after leaving PACU. We analyzed the late onset of RE in patients recovering from bariatric surgery and their opiate requirements through the firs...

Pulmonary gas exchange in breath-hold diving (BHD) consists of a progressive increase in arterial PO2 and PCO2 (PaO2 and PaCO2) during descent. However, recent findings have demonstrated that PaO2 does not consistently rise in all subjects. This study aimed at verifying and explaining PaO2 derangements during BHD analyzing arterial blood gases and...

Hypoxia and hyperoxia are both worrisome issues potentially affecting SCUBA divers, but validated methods to monitor these two conditions underwater are still lacking. In this experiment, a volunteer SCUBA diver was equipped with a pulse oximeter to detect peripheral oxygen saturation (SpO2) and a device to monitor the oxygen reserve index (ORi™)....

Introduction with Aim: Postoperative respiratory depression can complicate a patient’s recovery after surgery. A predictive score (PRODIGY) was recently proposed to evaluate the risk of opioid-induced postoperative respiratory depression. For the first time, we applied this score to a cohort of patients receiving bariatric surgery, stratified by Ob...

As the UHMS observes the distinguished anniversary of the publication of 50 volumes of the Undersea and Hyperbaric Medicine Journal, two of our past editors take a look at the evolution of our flagship publications.

Gas embolism is a potentially fatal occurrence in which bubbles are introduced into the arterial/venous circulation. A multifocal ischemia could be the life-threatening scenario of that and occurring after diving-related activities, or pulmonary barotrauma, or even iatrogenic procedure capable to cause an accidental introduction of gas into the vas...

Purpose Divers can experience cognitive impairment due to inert gas narcosis (IGN) at depth. Brain-derived neurotrophic factor (BDNF) rules neuronal connectivity/metabolism to maintain cognitive function and protect tissues against oxidative stress (OxS). Dopamine and glutamate enhance BDNF bioavailability. Thus, we hypothesized that lower circulat...

The history of direct cell-cell communication has evolved in several small steps. First discovered in the 1930s in invertebrate nervous systems, it was thought at first to be an exception to the “cell theory”, restricted to invertebrates. Surprisingly, however, in the 1950s, electrical cell-cell communication was also reported in vertebrates. Once...

Carbon Monoxide (CO) intoxication is still a leading cause of mortality and morbidity in many countries. Due to the problematic detection in the environment and subtle symptoms, CO intoxication usually goes unrecognized, and both normobaric and hyperbaric oxygen (HBO) treatments are frequently administered with delay. Current knowledge is mainly fo...

Background: The purpose of this study was to compare postoperative opioid consumption following total shoulder arthroplasty, after: (A) a single-shot undiluted liposomal bupivacaine (LB; commercial name: Exparel) interscalene block, or (B) a Ropivacaine block (R), supplemented with continuous catheter infusion. Methods: This prospective, randomized...

Background: Pulmonary gas exchange during diving or in a dry hyperbaric environment is affected by increased breathing gas density and possibly water immersion. During free diving there is also the effect of apnea. Few studies have published blood gas data in underwater or hyperbaric environments: this review summarizes the available literature an...

Objective: This study blindly evaluated sugammadex compared with neostigmine on length of stay in the postanesthesia care unit (PACU). Methods: Fifty patients undergoing elective laparoscopic cholecystectomy or abdominal wall hernia repair consented to receive either sugammadex (2 mg/kg) or neostigmine (0.07 mg/kg) for the reversal of rocuronium...

The perioperative management of vascular surgery patients requires an understanding of the underlying pathophysiology of the specific vascular bed involved. A significant challenge derives from the high risk for operations in patients with overt or occult coronary artery disease (CAD), the primary cause of perioperative and long-term mortality afte...

Background: Although many studies have shown that hyperbaric oxygen (HBO) therapy can significantly improve symptoms and quality of life of patients affected by femoral head necrosis, this therapy is still not yet approved worldwide. Therefore, a meta-analysis was performed to evaluate its clinical effect. Methods: Relevant studies published before...

Poster aimed to describe our recent experience on this issue (Emergency Occurence Simulations - Underwater and in a Hyperbaric Environment) during a post-graduate medical course.

Introduction Hyperbaric chambers and underwater environments are challenging and at risk of serious accidents. Personnel aiming to assist patients and subjects should be appropriately trained, and several courses have been established all over the world. In healthcare, simulation is an effective learning technique. However, there have been few peer...

Although many studies have shown that hyperbaric oxygen (HBO) therapy can significantly improve symptoms and quality of life of patients affected by femoral head necrosis, this therapy is not worldwide approved yet. This meta-analysis was performed to evaluate its clinical effect. Relevant studies published before May 2020 were systematically searc...

Introduction Noninvasive monitoring of partial pressure of carbon dioxide can be accomplished indirectly with capnography (PETCO2) or with transcutaneous carbon dioxide monitoring (PTCCO2). The use of capnography has been shown to offer an advantage over pulse oximetry alone in the early detection of adverse respiratory events when supplemental oxy...

Implantation is currently the best option for tooth replacement in periodontitis. Some major contraindications for the immediate implant are acute periodontitis and active infection. We present the case of a 51-year-old female patient with the highest grade and stage periodontitis treated with advanced platelet-rich fibrin-enriched zirconia implant...

Massive transfusion protocols (MTPs) facilitate the organized delivery of blood components for traumatically injured patients. MTPs vary across institutions, and ratios of blood components can change during clinical management. As a result, significant amounts of components can be wasted. We completed a review of all MTP activations from 2015 to 20...

The provision of anesthesia at high (>3000 m) altitude is possible, but with some alterations in technique. Changes in pulmonary physiology are the primary cause of complications under reduced pressures. Altered physiology may be seen in mountain expeditions, in airline travel, and in space. Usually accompanied by sparse or austere resources, medic...

Objective To evaluate reports from the published literature of all randomized clinical trials (RCT) comparing postoperative sedation with dexmedetomidine versus propofol in adult patients, after open cardiac surgery. Design A computerized search on Medline, EMBASE, Web of Science, and Agency for Healthcare Research and Quality databases was comple...

The recent coronavirus disease 2019 (COVID-19) pandemic produced high and excessive demands for hospitalizations and equipment with depletion of critical care resources. The results of these extreme therapeutic efforts have been sobering. Further, we are months away from a robust vaccination effort, and current therapies provide limited clinical re...

Introduction / Background: Often under-reported in incidence and features, especially in Italy, carbon monoxide (CO) poisoning is a frequent cause of intoxication. Under the aegis of ASPATI, a national association of patients treated with hyperbarism devoted to the promotion of an appropriate use of hyperbaric oxygen, a study has been conducted aim...

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At the date (May 29th, 2020): article peer-reviewed and accepted; in press. Background: The issue of prolonged diving has grown in importance, in light of the significant number of divers being lost at sea and exposed to prolonged immersion. Therefore, the aim of this longitudinal case study was to investigate the psychological and pathophysiologi...

At the date (May 29th, 2020): article peer-reviewed and accepted; in press. The "Endless Diving Project-Step 36" took place in the harbor waters of the town of Maratea in Italy in September 2014. The goal of the project was an attempt by an experienced male diver, equipped with a wet 7-mm suit and a normal gas tank, to set the world record-breakin...

At the date (May 29th, 2020): article peer-reviewed and accepted; in press. Background: The issue of prolonged diving has grown in importance, in light of the significant number of divers being lost at sea and exposed to prolonged immersion. Therefore, the aim of this longitudinal case study was to investigate the psychological and pathophysiologic...

Purpose Adaptations during voluntary breath-hold diving have been increasingly investigated since these athletes are exposed to critical hypoxia during the ascent. However, only a limited amount of literature explored the pathophysiological mechanisms underlying this phenomenon. This is the first study to measure arterial blood gases immediately be...

Background The efficacy and safety of dexmedetomidine in sedation for postoperative cardiac surgeries are controversial when compared to propofol. Methods A computerized search on Medline, EMBASE, Web of Science, and Agency for Healthcare Research and Quality databases was performed through July 2019. Trials evaluating the efficacy of dexmedetomidi...

Background: Carbon Monoxide (CO) poisoning is a frequent cause of intoxication. However, CO poisoning incidence is globally underreported, as well as its features, especially in Italy. The aim of this study was to investigate such characteristics of CO intoxication and foster the creation of the Italian Registry of Carbon Monoxide Poisonings. Metho...

Background and Objectives: Inflammation is considered a risk factor for venous thromboembolism. The association between inflammatory markers and the severity of acute pulmonary embolism (APE) has not been explored. Methods: We studied the association between two crude markers of inflammation, serum albumin, and red cell distribution width (RDW) and...

Objectives: To report our updated experience with the morbidity of nonemergent hysterectomy for placenta accreta. As a secondary objective we sought to compare two cohorts over time to see whether there was a significant difference in morbidity. Design: Retrospective chart review. Materials and Methods: Adding to data we published in 2010, this was...

Abstract Background Interstitial Cystitis (IC) is a debilitating disorder of the bladder, with a multifactorial and poorly understood origin dealing with microcirculation repeated damages. Also Fibromyalgia (FM) is a persistent disorder whose etiology is not completely explained, and its theorized alteration of pain processing can compromise the qu...

Background : The use of dexmedetomidine for sedation post-cardiac surgery is controversial compared to the use of propofol. Methods : A computerized search on Medline, EMBASE, Web of Science, and Agency for Healthcare Research and Quality databases was performed for up to July 2019. Trials evaluating the efficacy of dexmedetomidine versus propofol...

Objective: Few reports have evaluated postoperative continuous thoracic epidural analgesia on patients who received a lung transplant. This analgesic modality may facilitate extubation, early ambulation, and achieve adequate pain control with minimization of opioid use. An opioid sparing technique could minimize the side effects of opioids such as...

Objective: Current literature debates whether administration of sugammadex translates into a higher operating room (OR) efficiency when compared to neostigmine. This study is a blinded assessment of the effects of sugammadex versus neostigmine on OR efficiency as determined by time of reversal to time of the next case.Methods: 50 patients undergoin...

Background: Inappropriate management of anesthetic medications requiring refrigeration creates waste and increases costs of intraoperative care. At Tampa General Hospital, pharmacy personnel refill medications in cardiovascular operating rooms (CVOR) nightly and noticed large amounts of unattended medications at room temperature for unknown period...

The use of hyperbaric oxygen plays a significant role in many aspects of medicine. However, there are few studies that analyzed the role of hyperbaric oxygen, in addition to physical exercise, on the endocrine profile. The aim of this study was to compare changes in plasma male sex hormones after hyperbaric physical exercise with different hyperbar...

BACKGROUND: The efficacy and safety of dexmedetomidine in sedation for postoperative cardiac surgeries is controversial when compared to propofol. METHODS: A computerized search of Medline, Cochrane and Google Scholar databases was performed through August 2018. Studies evaluating the efficacy of dexmedetomidine versus propofol in the sedation of p...

The present study aimed to evaluate the partial pressure of arterial blood gases in breath-hold divers performing a submersion at 40 m. Eight breath-hold divers were enrolled for the trials held at "Y-40 THE DEEP JOY" pool (Montegrotto Terme, Padova, Italy). Prior to submersion, an arterial cannula in the radial artery of the non-dominant limb was...

Dentigerous cysts form during tooth development. Formation of the cyst primarily occurs in impacted or unerupted teeth. Maxillary involvement for dentigerous cysts is exceedingly rare. as such, the literature on removal of maxillary dentigerous cysts is limited. Furthermore, the surgical technique traditionally utilized for treatment of a dentigero...

Introduction: Hyperbaric oxygen (HBO2) therapy is emerging internationally as the primary treatment modality for inflammatory pathways related to neurological disorders. Currently, literature concerning its effectiveness in autistic children is limited. Using neurocognitive tests and clinical-diagnostic evaluations, this study evaluates the clinica...

Introduction: Hyperbaric oxygen (HBO2) therapy is emerging internationally as the primary treatment modality for inflammatory pathways related to neurological disorders. Currently, literature concerning its effectiveness in autistic children is limited. Using neurocognitive tests and clinical-diagnostic evaluations, this study evaluates the clinic...

Dermatobia hominis, commonly known as the human botfly, is native to Tropical America. As such, cutaneous infestation by its developing larvae, or myiasis, is quite common in this region. The distinct dermatological presentation of D hominis myiasis allows for its early recognition and noninvasive treatment by locals. However, it can prove quite pe...

Early stages of avascular necrosis of the femoral head (AVNFH) can be conservatively treated with hyperbaric oxygen therapy (HBOT). This study investigated how HBOT modulates inflammatory markers and reactive oxygen species (ROS) in patients with AVNFH. Twenty-three male patients were treated with two cycles of HBOT, 30 sessions each with a 30 days...

Background Osteonecrosis of the knee (ONK) is a form of aseptic necrosis resulting from ischemia to subchondral bone tissue. Typically, treatment is invasive. Hyperbaric oxygen therapy (HBOT) may provide a noninvasive alternative by improving oxygenation and reperfusion of ischemic areas. This study evaluates the efficacy of HBOT in a series of ONK...

Femoral head necrosis (FHN) is a disease process resulting from inadequate blood perfu-sion of subchondral bone. While the etiology of this disease is still not fully understood, there are multiple traumatic and atraumatic factors that are associated with the disease. Pathophysiology of the disease is characterized by the death of bone marrow and o...

Background and Objectives During storage, red blood cells (RBCs) undergo physicochemical changes which affect the quality, function, and in vivo survival of transfused packed RBCs (pRBC). Changes include decreased 2,3‐diphosphoglycerate (2,3‐DPG) levels, decreased ATP, changes in mechanical properties and oxidative injury. RBC rejuvenation is a met...

Introduction Ischemia/reperfusion (I/R) injury, such as myocardial infarction, stroke, and peripheral vascular disease, has been recognized as the most frequent causes of devastating disorders and death currently. Protective effect of various preconditioning stimuli, including hyperbaric oxygen (HBO), has been proposed in the management of I/R. Me...

Ketogenic diet is being increasingly utilized in recent decades because of its success as an effective tool for short and intermediate-term weight loss. Promoting physiological ketosis from a drastically low carbohydrate diet is the fundamental basis for this diet regime. though debated, these diets have been demonstrated to be effective, at least...

BACKGROUND: Avascular necrosis of the femoral head (ANFH) is a progressive and debilitating disease which eventually requires hip joint surgery. In this retrospective study, we evaluated the efficacy of hyperbaric oxygen treatment (HBO) in ANFH patients (FICAT I-II-III) for four consecutive years. METHODS: 217 patients with ANFH, enrolled from 2004...

Introduction: Hyperbaric oxygen (HBO₂) therapy and use of enriched air can result in oxidative injury affecting the brain, lungs and eyes. HBO₂ exposure during diving can lead to a decrease in respiratory parameters. However, the possible effects of acute exposure to oxygen-enriched diving on subsequent spirometric performance and oxidative state...

Central Nervous System Oxygen Toxicity (CNS-OT) is one of the most harmful effects of Enriched Air Nitrox (EAN) diving. Protective factors of the Ketogenic Diet (KD) are antioxidant activity, the prevention of mitochondrial damage and anti-inflammatory mechanisms. We aimed to investigate if a short-term KD may reduce oxidative stress and inflammati...

Man’s experience and exploration of the underwater environment has been recorded from ancient times and today encompasses large sections of the population for sport enjoyment, recreational and commercial purpose, as well as military strategic goals. Knowledge, respect and maintenance of the underwater world is an essential development for our futur...

Introduction/Background: This study evaluates the effects of continuous thoracic epidural analgesia (TEA) vs. intravenous pain control methods on the narcotics requirement for common laparoscopic abdominal surgeries. The introduction of new guidelines at Tampa General Hospital for the year 2017 afforded the opportunity for a sequential case series...

We have previously identified 13 interventions that might change perioperative mortality in adult surgery, among them are perioperative β-blockers (BB). The increased prevalence of cardiovascular (CV) disease together with the awareness of the survival benefit of BB in various cardiac pathologies, promoted a dramatic increase in its utilization. A...

Obstructive sleep apnea (OSA) is prevalent in patients presenting with upper airway obstruction due to an enlarged tongue base. Here we describe a novel method of using a video-laryngoscope, the GlideScope®, to perform coblation of the tongue base for these select patients. The patient presented in this case report is a 67-year-old male who had two...

Use of anesthesia in the HBO environment is unusual. This chapter gives a historical perspective and describes the physics of anesthetic gases under pressure as well as the relevant physiology. There are practical aspects of anesthesia in hyperbaric environment of the chamber and several clinical indications are mentioned that require especially di...

It is widely accepted that O2 pretreatment before diving can be used for tissue denitrogenation, may reduce decompression requirements, and allows for a quicker restoration of platelet function after a decompression episode. Previous studies presented that anti-oxidative enzymes and related genes in the central nervous system such as catalase (CAT)...

Introduction: There are conflicting data regarding the prognostic value of syncope in patients with acute pulmonary embolism (APE). Methods: We retrospectively reviewed data of 552 consecutive adults with computed tomography pulmonary angiogram-confirmed APE to determine the correlates and outcome of the occurrence of syncope at the time of pres...

Background: Femoral head necrosis (FHN) is a common invalidating disease with an unclear etiology and pathophysiology that affects middle-aged people. FHN may lead to joint collapse and require invasive treatments. Because of its clinical and socioeconomic significance, an early diagnosis, staging and appropriate treatment are required. Unfortunate...

Hyperbaric oxygen therapy in the treatment of complex regional pain syndrome. You're going to find more @: https://www.uhms.org/asm17-presentations/f-1-poster-hyperbaric-oxygen-therapy-in-the-treatment-of-complex-regional-pain-syndrome/viewdocument.html

Introduction Patients with obstructive sleep apnea (OSA) commonly experience difficulty tolerating positive airway pressure (PAP) therapy. Drug Induced Sedation Endoscopy (DISE) assesses airway characteristics while the patient is sedated and may help guide alternative interventions for OSA. Since DISE is performed in the operating room, its cost i...