Emmanuel Simon

Emmanuel Simon
University of Calicut · Department of Life Sciences

Professor

About

4
Publications
331
Reads
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55
Citations
Citations since 2016
1 Research Item
35 Citations
201620172018201920202021202202468
201620172018201920202021202202468
201620172018201920202021202202468
201620172018201920202021202202468
Introduction
Molecular studies on interaction of small molecules with macromolecules in cells.
Additional affiliations
September 2009 - present
University of Calicut
Position
  • Assitant Professor Department of Lifesciences
September 2008 - September 2009
Bhabha Atomic Research Centre
Position
  • biological activities of curcumin analogs
September 2007 - June 2008
University of Kerala
Position
  • Evaluation of the neuroprotective effects of the ayurvedic drug Ksheerabala
Education
August 2001 - December 2003

Publications

Publications (4)
Article
Curcumin is a polyphenol derived from the herb Curcuma longa, which has been extensively studied in terms of its antitumour, antioxidant, and chemopreventive activity as well as various other effects. In the present work we compared curcumin with its synthetic analogue dimethoxycurcumin (dimc) in terms of its antioxidant enzyme-modulating effects i...
Article
Dimethoxycurcumin (Dimc), a synthetic analogue of curcumin, that has been reported to exhibit better in vivo stability and anti-tumour activity, was investigated for its interaction with DNA, employing spectroscopic methods based on absorption, fluorescence, circular dichroism (CD), ethidium bromide (EtBr) competitive binding assay, 4'-6-diamidino-...
Conference Paper
Dimethoxycurcumin(DIMC) a synthetic analogue of curcumin is reported to exhibit higher anticancer activity and metabolic stability over curcumin and has the potential to be developed into an anticancer drug. In the present work we have studied the interaction of DiMC with calf thymus dna (ct-DNA) employing UV absorption and flurescence spectroscopy...
Conference Paper
Interaction of curcumin analogue bis-dimethoxycurcumin with DNA Emmanuel Simon1, U. Singh1, A. Kunwar1, S. Santosh Kumar, K. I. Priyadarsini1 1Radiation & Photochemistry Division, 2Radiation Biology & Health Sciences Division, Bhabha Atomic Research Center, Mumbai-400085, India Bis-dimethoxycurcumin (BDMC) a synthetic analogue of curcumin is repo...

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Projects

Project (1)
Archived project
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