Emir Horozić

Emir Horozić
University of Tuzla | UNTZ · Department of Organic Chemistry

MSc

About

53
Publications
19,790
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181
Citations
Additional affiliations
October 2017 - October 2021
University of Tuzla
Position
  • Junior Assistant
Education
October 2021 - June 2024
University of Tuzla
Field of study
  • Applied Chemistry
October 2017 - February 2019
University of Tuzla
Field of study
  • Chemistry and Materials Engineering
October 2012 - October 2016
University of Tuzla
Field of study
  • Chemistry

Publications

Publications (53)
Article
Full-text available
Two highly invasive plant species, Lysimachia vulgaris and Lythrum salicaria are well-known for their anti-in-flammatory, hemostatic, and antidiarrheal activity. These plants are most widespread on the territory of Eu-roasia, where their traditional medicinal use has been reported. Due to their invasiveness, they are undesirable plants in other par...
Article
Full-text available
Bitter and sweet wormwoods are traditional plant species in the Asteraceae (Compositae). Their use in traditional medicine has long been known. Numerous preparations of bitter and sweet wormwood (teas, tinctures) are used in the treatment of diseases of the digestive system. The content of bioactive components (polyphenols and flavonoids) and antio...
Article
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2-acetoxy-benzencarboxylic acid is one of the most famous salicylate drugstoday, a pharmaceutically active compound known as aspirin. It is poorly so-luble in water which results in decreased bioavailability of the drug in the or-ganism. The increase in water solubility of insoluble or poorly soluble drugs istherefore of great importance, which is...
Article
Vaginal inflammation represents a heterogeneous group of disorders caused by infection, inflammation, or disruption of vaginal microflora. The most common causes of vaginal infection are Staphylococcus aureus, Enterococcus faecalis, Streptococcus agalactiae, Escherichia coliand Candida albicans. Antibiotic resistance is a major global problem, whic...
Article
Full-text available
Tussilago farfara L., also known as coltsfoot, is a plant that has been used since ancient times to relieve coughs. Subsequently, the effectiveness of coltsfoot in the treatment of bronchial asthma, pneumonia and other respiratory diseases was established. In this research, the antioxidant and antimicrobial activity of different coltsfoot extracts...
Article
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Capsella bursa-pastoris (L.) Medik. (known as shepherd's purse) is a plant whose parts are used as medicine in herbal medicine. It is applicable as a medicine in the treatment of all forms of internal bleeding, for the treatment of hemorrhoids, excessive menstruation, but also for the usual stopping of nosebleeds. Through this research, the influen...
Article
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Essential oils are mixtures of potent compounds with biological effects, such as those with antioxidant, antimicrobial, antitumor and/or anti-inflammatory effects. In this paper, the antioxidant and antimicrobial activity of essential oils of different types of commercial pepper was tested. Essential oils are prepared by hydrodistillation. Polyphen...
Article
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In this research, the antioxidant activity and its correlation with the polyphenolic content in pumpkin leaf extracts (Cucurbita pepo L.) were examined. Dried and pulverized pumpkin leaves were used as extraction material. Various solvents (water, methanol, ethanol, acetone) and their mixtures, in a ratio of 50:50 (v/v) (water: methanol, water: eth...
Article
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Hibiscus is a widely used plant, which has been proven to have numerous positive effects on human health, such as lowering blood pressure, maintaining optimal blood cholesterol levels, liver protection, prevention of oxidative stress, etc. In this study, the content of polyphenols, flavonoids and antioxidant capacity of aqueous, ethanolic and hydro...
Article
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Copper (II) complexes with commercial antibiotics, amoxicillin (AMX), azithromycin (AZT) and ciprofloxacin (CFL) were synthesized and isolated as solids. Structures of the isolated products were determined by FTIR spectroscopy. Antibacterial activities were determined on reference bacterial strains from the ATCC collection by diffusion technique. T...
Article
The samples of stinging nettle were collected during June in the Tuzla region. Aqueous extracts were prepared from fresh and dried leaves in order to determinate and compare content of bioactive components and antioxidant potential. Conventional soxhlet, ultrasound assisted extraction and traditional maceration extraction were used as extraction me...
Article
Full-text available
Metal complexes due to their antibacterial, antifungal, antitumor and antioxidant properties have been extremely studied today. A large number of metal complexes have the ability to neutralize free radicals, which most often occur as a result of metabolic processes in the body, smoking, exposure to radiation and chemical substances. Testing the ant...
Article
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Pepper is one of the most famous and widespread spices in the world. This commercial plant belongs to the Piperaceae family. Depending on the treatment to which the pepper fruit is exposed, we distinguish between black, white and green pepper. In this research, methanolic extracts of different types of pepper (Piper nigrum) and pink pepper (Schinus...
Article
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Aims: The aims of the study were to analyse the polyphenols of Pulicaria dysenterica (L.) Bernh. methanolic extracts from aerial and underground parts, assessment of antioxidant activity and to evaluate their cytotoxicity on HeLa cells of cervical cancer. Methodology: The total phenolic content (TPC) of extracts was determined by the Folin-Ciocalte...
Article
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Telekia speciosa (Schreb.) Baumg., Asteraceae, is widespread in Eastern and Central Europe and the Balkan Peninsula. Previous phytochemical investigations have revealed T. speciosa as a rich source of sesquiterpene lactone-isoalantolactone, especially in its underground parts. The aim of the present study was to analyze the essential oils from aeri...
Article
Full-text available
Pepper (Piper Nigrum) is an extremely important plant species for which antimicrobial, anti-inflammatory, anti-mutagenic, anti-tumour and antioxidant activity has been confirmed. In this paper, extracts of black, red, green and white pepper in methanol were prepared. The possible antioxidant effect of the extracts was investigated using the DPPH me...
Article
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In this study, metal complex of Copper(II) with a Schiff base derived from 2,2-dihydroxyindane-1,3-dione and 2-aminoethanoic acid were synthesized. The product are characterized by spectral methods. The antimicrobial activity was tested on reference bacterial strains and the antioxidant capacity was analyzed by using the DPPH and FRAP methods. The...
Article
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In this paper, the polyphenol content and antioxidant activity of fig leaf extracts were analyzed. Extraction was performed with methanol, ethanol, acetone and their aqueous mixtures (50:50 v/v). Extractions were performed with stirring at 300 rpm on a vibromix and ultrasonic bath for 15 minutes. The polyphenol content was determined spectrophotome...
Article
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In this paper, three complexes with 8-hydroxyquinoline (8-HQ) were synthesized, their spectral analysis was performed and the antimicrobial effect was examined in vitro. The stoichiometric ratio of the complex was determined conductometrically and spectrophotometrically. FTIR and UV/VIS spectroscopy were used for structural characterization. Antimi...
Book
Naučno-stručna knjiga „Antioksidansi“ nastala je kao rezultat dugogodišnjeg rada na polju analize antioksidativne aktivnosti različitih uzoraka. Brzi način života dovodi do poremećaja homeostaze organizma, nastanka oksidativnog stresa koji može biti okidač razvoja širokog spektra bolesti. Zbog toga je jako važno osvijestiti populaciju o značaju ant...
Article
Full-text available
Telekia speciosa (Schreb.) Baumg., Asteraceae, is widespread in Eastern and Central Europe and the Balkan Peninsula. Previous phytochemical investigations have revealed T. speciosa as a rich source of sesquiterpene lactone -isoalantolactone, especially in its underground parts. The aim of the present study was to analyze the essential oils from aer...
Article
Full-text available
The chemistry of complex compounds containing imine ligands is attracting significant attention from researchers today. In this work, complexes of selected transition metals (Cu, Co, Ni and Fe) with imines based on ninhydrin and amino acids methionine and cysteine were synthesized. FTIR and UV/VIS spectroscopy were used for structural characterizat...
Article
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Origanum compactum (Lamiaceae) is an endemic species of oregano from Morocco, and the main components are carvacol and thymol, which are considered to have antimicrobial activity. Essential oils can be unstable, poorly soluble in water and poorly delivered to target cells. The incorporation of essential oils into liposomes can reduce their irritant...
Article
Research into the use of metal complexes as potential drugs is extremely popular and yields promising results. In this research, a group of metal complexes based on 2,2-dihydroxyindane-1,3-dione and selected amino acids (histidine and phenylalanine) was synthesized. FTIR and UV/VIS spectroscopy were used for structural characterization. Antimicrobi...
Article
Full-text available
In this study, the efficacy of different extraction techniques (maceration, ultrasound-assisted and Soxhlet extraction) on the content of biologically active components in extracts from fresh and dried nettle leaves, and their antioxidant activity were analyzed. Methanol was used as the solvent. Total phenolic content and antioxidant capacity were...
Article
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Onečišćenje zraka se sve više smatra značajnim rizikom po zdravlje stanovništva. Uslijed rada industrije, velike koncentracije prometa i individualnih ložišta, na području grada Tuzle već je dulje vrijeme prisutan problem onečišćenja zraka. Tvari koje onečišćuju okoliš predstavljaju rizik za zdravlje ljudi i drugih živih bića, a onečišćenje zbog sa...
Article
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Deep eutectic solvents (DESs), as an alternative to ionic liquids, have greener credentials than ionic liquids and have attracted increasing attention in many applications. Choline chloride-based DESs in combination with different hydrogen bond donors (organic acid, sugars and urea), showed a high extraction efficiency. The aim of this study was to...
Article
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In this work, four silver(I) complexes with Schiff bases derived from ninhydrin and selected amino acids (methionine, histidine, cysteine, and phenylalanine) were synthesized. The aim of this study is to determine the potential biological activity of these complexes. FTIR and UV/VIS spectroscopy were used for structural characterization of the prod...
Article
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This paper presents the results of influence of extraction technique on phytochemical composition and biological activity of aqueous extracts of commercial apricot kernels. Three techniques were used for extraction: maceration, ultrasonic and Soxhlet extraction. The content of total phenols, flavonoids, bioelements, antioxidant and antimicrobial ac...
Article
Cloud point extraction (CPE) is an attractive technique that reduces solvent con- sumption and exposure, disposal costs, and process time. This method has an im- portant practical application and is used to separate and concentrate the analyte as a step before its determination, and after the formation of a poorly water-soluble complex. Use of noni...
Article
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Arylmethylenebis(3-hydroxy-5,5-dimethyl-2-cyclohexen-1-one) derivatives (aryl=2-hydroxynaphthyl (1) and 3,4-dihydroxyphenyl (2) have been synthesized and their structures have been elucidated. Both compounds were examined for their antioxidant, antimicrobial and cytotoxic activity. Antioxidative activities of synthesized compounds were evaluated by...
Article
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Schiff bases are organic compounds formed by the reaction of the primary amine with carbonyl compounds (aldehydes or ketones). These are mainly bi- or tridentate ligands capable of forming very stable complexes with transitional metals. They are used as catalysts in oxygenation, hydrolysis, electro-reduction and decomposition reactions. Many Shiff...
Article
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he aim of this study is to synthesize, characterize and detect the potential biological activity of a complexes of selected biologically significant metals with 4,4,4-trifluoro-1-(2-thienyl)-1,3-butanedione (TTA). Spectroscopic methods were used for the structural characterization of the products. Crystal morphology was analyzed using a binocular m...
Chapter
Imines are organic compounds which in their structure have a double bond between one carbon and one nitrogen atom. Forms very stable complexes with transition metals, which are now widely tested in order to detect a potential catalytic and pharmacological activity. This study involves the synthesis of imines and complexes with biogenic bivalent met...
Article
Full-text available
The aim of this work was to investigate the interaction of Imatinib mesylate with biological ions Cu(II), Co(II) and Ni(II) in ethanol/water solutions. Structures of synthesized complexes were characterized by spectroscopy methods. The results of IR spectros-copy showed that biogenic metal complexes with ImM were formed through the oxygen donors of...
Article
Full-text available
Spring saffron (lat. Crocus vernus (L.)Hill) is a perennial from the Iridaceae family. Purple or white coloured flowers bloom in the early spring. Saffron is commonly used in cookery, but because of its healing properties, crocus is also used in medicine for improving blood circulation, treating the cardiovascular diseases, preventing tumour and he...
Article
Full-text available
pABA (p-aminobenzoic acid or 4-aminobenzoic acid) is a chemical component of the folate molecule produced by plants and bacteria, and found in many foods. It is best known as a UV-blocking sunscreen applied to the skin, and is sometimes taken orally for certain medical conditions. Today it is known that many organic molecules in the human body can...
Article
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Many studies have shown that coniferous tree extracts have a high antioxidant, antimicrobial and antiproliferative effect. This study examined the content of bioactive components, antioxidant and antimicrobial activity of Larix decidua Mill., Picea abies (L.) Karst. and Pinus nigra J.F. Arnold methanol extracts. Antioxidant activity was determined...
Article
Full-text available
Schiff bases and complexes are today the subject of many studies because of the established biological, inhibitor and catalytic properties. The aim of this paper is to investigate the interaction of Schiff base obtained by reaction of 2,2-dihydroxyindane-1,3-dione (ninhydrin) and the essential amino acid tryptophan with copper(II) ion. Spectral cha...
Article
The use of nanotechnology in the diagnosis of diseases, treatment and monitoring of cancer patients has become a subject of study for the last 20 years. This paper presents brief overview of general characteristics, synthesis and application of dendrimers and quantum dots (QDs) in oncology. Dendrimers and quantum dots (QDs) are nanostructures whose...
Article
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Ciprofloxacin, CFL is a drug that belongs to the second generation of fluoroquinolone antibiotics with a wide range of effects on Gram-positive and Gram-negative bacteria. The aim of this work was to investigate the interaction of CFL as ligand with divalent biological cations (Mn2+, Ni2+ and Co2+) in approximate physiological conditions. Synthesiz...
Article
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Određivanje fenola u urinu smatra se prikladnim biomarkerom izloženosti benzenu, koji je klasificiran u grupu A kancerogena od strane Međunarodne agencije za istraživanje raka (IARC) i Agencije za zaštitu okoliša (EPA). U ovom radu testirana je ponovljivost nekoliko metoda za analizu fenola u urinu primjenom tekućinske kromatografije visoke djelot...
Article
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1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (Ciprofloxacin, CFL) is a drug that belongs to the second generation of fluoroquinolone antibiotics with a wide range of effects on Gram-positive and Gram-negative bacteria. The bactericidal action of ciprofloxacin results from the inhibition of the enzymes topoi...
Article
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Biodegradable polymers (biopolymers) represent materials of new generation with application in different areas of human activity. Their production has recently reached a commercial level. They can be divided according to the origin (natural and synthetic), according to the chemical composition, methods of obtaining, application etc. The use of biop...
Article
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Malignant neoplasms are today one of the leading causes of death in the world. Their treatment is extremely complex and requires the application of various chemical compounds which leads to disruption of homeostasis in the human body. During a treatment, there is a possibility of complex formation with important bioelements, such as copper, iron, c...
Article
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Due to the growing demand for food production, agricultural areas are spread, production is intensified, various illegal activities are carried out in order to achieve higher yields and better resistance leading to increased concerns on the environment. This paper studied the soil of mountain areas in north-eastern Bosnia and Herzegovina, in which...
Article
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Cobalt and copper are present as trace elements in biological systems and they are very important for the activity of many enzymes with different functions in the body. Their biological functions derive from the possibility of potential interaction of their M(II) ions with O, N and S donor atoms of various ligands and biomolecules in the living org...

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