
Eloi DezanSão Paulo State University | Unesp · Departamento de Odontologia Restauradora (Araçatuba)
Eloi Dezan
Professor of Endodontics
About
160
Publications
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Introduction
Eloi Dezan currently works at the Restorative Departament (Araçatuba), São Paulo State University. Eloi does research in Dental Surgery and Restorative Dentistry and Endodontics. Their current project is 'Cleaning Effectiveness of Titanium Ultrasonic Tips: An Environmental Scanning Electron Microscopic Study'.
Skills and Expertise
Publications
Publications (160)
The evolution of biomaterials engineering allowed for the development of products that improve outcomes in the medical–dental field. Bioglasses have demonstrated the ability to either compose or replace different materials in dentistry. This study evaluated the cytotoxicity, biocompatibility, calcium deposition, and collagen maturation of 45S5 biog...
Bone defects may be a result of different pathologies and represent a challenge in different fields of dentistry. Techniques for the correction of bone defects involving the use of several types of grafts have been proposed. This study evaluated bone repair in rat tibiae after surgically created critical-size defects were filled with β-tricalcium p...
Objectives
This systematic review and meta-analysis (SRM) aimed to evaluate the efficacy of laser phototherapy (LPT) on the reduction in postoperative pain (PP) of endodontic origin after conventional/non-surgical reintervention of root canals.
Methods
This SRM was registered with PROSPERO (CRD42021243500) and followed the guidelines of the Prefer...
Biocompatibility and biomineralization of root canal dressings are important requirements for periapical healing. This study evaluated the inflammatory response, biomineralization and tissue repair by collagen fiber maturation in the subcutaneous tissue of rats. Eighteen Wistar rats (n = 6) received subcutaneous implants: calcium hydroxide + propyl...
Objective
To evaluate the effects of cigarette smoke inhalation on the immune‐inflammatory profile of experimental apical periodontitis in rats.
Methodology
In total, 32 male Wistar rats were divided into four groups ( n = 8): AP—induced apical periodontitis; S—cigarette smoke inhalation; APS—induced AP and cigarette smoke inhalation; and C (contr...
The purpose of this study was to evaluate, in vivo, the biocompatibility, biomineralization, collagen maturation and the in vitro antibacterial and cytotoxicity of resinous endodontic sealers containing calcium hydroxide. Forty rats were implanted with polyethylene tubes containing Sealer 26, Sealer Plus, Dia-ProSeal and an empty tube, examined aft...
Aim:
To evaluate the effects of cigarette smoke inhalation (CSI) on inflammation, proinflammatory mediators and haematological parameters in rats with induced apical periodontitis (AP).
Methodology:
Thirty-two 3-month-old male Wistar rats were divided into four experimental groups (n=8): C - Control; S - rats with CSI; AP - rats with AP; and SAP...
O objetivo do estudo foi avaliar a presença de imunomarcadores fibronectina e tenascina em subcutâneo de rato com cimento reparador biocerâmico Biodentine®, quando comparado ao MTA Branco Angelus® e Ca(OH)2 . Foram implantados tubos de polietileno no subcutâneo de 32 ratos machos Wistar contendo os materiais e um tubo vazio para controle (n = 8 ani...
A pulpotomia é uma opção de tratamento conservador que têm como função preservar a vitalidade pulpar na porção radicular, com o uso de materiais biocompatíveis sobre este tecido remanescente. Este estudo teve como objetivo avaliar a resposta biológica do remanescente pulpar frente aos cimentos biocerâmicos reparadores Biodentine® e MTA Branco Angel...
Aims:
The aim of this study was to evaluate the biocompatibility of resinous root canal sealers: Sealer 26, AH plus, and SK Seal Root Canal Sealer in the subcutaneous tissue of rats.
Subjects and methods:
Twenty-four Wistar rats received polyethylene tubes containing the sealers and empty tubes as control (n = 6). After 7, 15, 30, and 60 days, a...
This research evaluated, in vivo, the accuracy of three electronic apex locators - EALs (Root ZXII, E-PEX and FIND) in teeth with vital pulp submitted to biopulpectomy, preserving the periodontal stump. For this study, 90 single-rooted teeth with extraction indication were selected. After positive pulpal cold sensitivity test, pulp chamber access w...
O objetivo deste estudo foi avaliar a biocompatibilidade do cimento biocerâmico reparador Biodentine® quando comparado ao MTA Branco Angelus® e hidróxido de cálcio. Para isso foram utilizados vinte e quatro ratos Wistar (n=6 animais/grupo), divididos em quatro tempos experimentais de 7, 15, 30 e 60 dias. Os animais receberam implantes subcutâneos d...
Pacientes portadores de necessidades especiais costumam ser defensivos ou demonstram extrema ansiedade durante atendimento odontológico convencional, necessitando de tratamento em âmbito hospitalar, sob anestesia geral. Paciente diagnosticado com autismo foi atendido no ambulatório do CAOE (FOA/UNESP). Na avaliação clínica e radiográfica foi detect...
The objective of this study was to evaluate, in vivo, coronal bacterial infiltration after endodontic treatment with different obturation technique. Forty-five dogs’ root canals, originated from incisors and premolars, were used. The animals were intubated after general anesthesia. After local antisepsis and placement of rubber dam isolation, teeth...
Objectives:
This study compared the cytotoxicity, biocompatibility, and tenascin immunolabeling of a new ready-to-use hydraulic sealer (Bio-C Sealer) with MTA-Fillapex and white MTA-Angelus.
Materials and methods:
L929 fibroblasts were cultivated and exposed to undiluted and diluted material extracts. Polyethylene tubes with or without (the cont...
Fundamento: uma boa condição dos tecidos moles é necessária para a longevidade de tratamentos com implantes dentários. Os tecidos moles periimplantares são semelhantes ao periodonto de proteção, sendo importante para oferecer uma barreira contra a agressão bacteriana ao tecido ósseo. Objetivo: o objetivo foi realizar uma revisão de literatura sobre...
This study evaluated the biocompatibility, biomineralization, and collagen fiber maturation induced by Resorbable Tissue Replacement (RTR®; β-tricalcium phosphate [TCP]), Bioglass (BIOG; bioactive glass), and DM Bone® (DMB; hydroxyapatite and β-TCP) in vivo. Sixty-four polyethylene tubes with or without (control group; CG) materials (n=8/group/peri...
Objetivo: Avaliar a influência de diferentes plugs de proteção, acomodados sobre o remanescente da obturação após preparo para pino, na retenção de pinos metálicos fundidos. Métodos: Cinquenta dentes bovinos foram decoronados, manualmente instrumentados até a lima manual Kerr #80 e obturados. A desobturação parcial de 10mm do conduto foi realizada...
Background:
There are few studies on the influence of methylene blue as a photosensitiser on the mechanical properties and adhesion of glass-fiber posts to intraradicular dentin. Thus, this in vitro study aimed to evaluate the influence of photodynamic therapy with a methylene blue photosensitizer on the Martens hardness, elastic modulus, and bond...
Objetivo: apresentar o relato de um caso de tratamento viável para molar inferior permanente endodonticamente tratado que apresentou sintomatologia após 6 meses do tratamento endodôntico. Uma vez que retratamento endodôntico ou cirurgia parendodôntica não eram indicados, o reimplante intencional foi a técnica escolhida. Relato de caso: uma hora ant...
Bacteria are observed in the entire human body. When colonizing or forming biofilm in the oral cavity, may lead to primary, persistent or recurrent infections, resulting in destruction of dental hard and soft tissues. Since in health sciences, decreasing or eliminating bacterial levels is directly related to success, there has been a continuous eff...
Conservative pulp therapies are therapeutic maneuvers that allow the conservation of tooth vitality, such as indirect pulp-capping, direct pulp-capping, and pulpotomy. All these therapies aim essentially at maintaining pulp vitality and inducing formation of tertiary dentin. However, preservation of the dental pulp depends on its condition, such if...
Biomaterials are conceptualized as natural or synthetic materials used in contact with biological systems with the purpose of repairing or replacing lost hard or soft tissue. Ceramics are inorganic materials made by the heating of raw materials. Thus, the term “bioceramics” refers to biocompatible ceramic materials, preferential not only bio-inert,...
This clinical study compared the effectiveness of two rotary systems: HyFlex CM (Coltene-Whaledent, Altstetten, Switzerland) and ProTaper Next (Dentsply Sirona, Ballaigues, Switzerland) on the removal of cultivable bacteria and endotoxins from primarily infected root canals. This study was designed as a randomized single-blinded, 2-arm, clinical tr...
Objective
The aim of this study was to evaluate the relationship between length of root canal obturation (RCO) and the presence of apical periodontitis (AP) in different dental groups using cone-beam computed tomography (CBCT) analysis. Materials and methodsA total of 392 roots with canal treatment performed for more than 4 years were evaluated usi...
This study aimed to assess the cyclic fatigue resistance of Genius and EdgeFile X1 reciprocating instruments compared with WaveOne Gold Primary. Twenty Genius (Ultradent) 25.04, 20 Genius 30.04, 20 EdgeFile X1 (EdgeEndo) and 20 WaveOne Gold Primary (Dentsply Maillefer) instruments were included in this study and tested in a static cyclic fatigue te...
In endodontic treatment, regardless of the instrumentation technique, the presence of a smear layer covering contaminated dentin walls is always a concern. Thus, irrigation plays an essential role in reducing bacterial load. To enhance irrigation effectiveness, different ultrasonic activation methods and the use of different tips have been studied....
Background: The effects of using curcumin as photosensitizer on the mechanical properties of intraradicular dentin and on the bond strength of glass-fiber posts are unknown. Thus, this in vitro study evaluated the influence of using curcumin as photosensitizer during photodynamic therapy on the Martens hardness, elastic modulus, and bond strength o...
Aim
Carvedilol is an antioxidant that decreases inflammation in periodontitis. The hydrogen peroxide (H2O2) of bleaching gel causes inflammation and necrosis of the dental pulp. In the present study, we evaluated the anti‐inflammatory potential of carvedilol in the pulp of rats after bleaching.
Methods
The right upper molars of rats received 35% H...
Objective:
Evaluate, in vivo, the biocompatibility via subcutaneous inflammatory tissue response and mineralization ability of the new MTA Flow compared to MTA Angelus and ProRoot MTA.
Materials and methods:
Forty male Wistar rats were assigned and received subcutaneous polyethylene tube implants containing the test materials and a control group...
Bleaching gel containing hydrogen peroxide (H2O2) cause damages in pulp tissue. This study investigated the action of a topical anti-inflammatory, the Otosporin®, in rats’ bleached teeth with the null hypothesis of which the Otosporin® is no able to minimize the pulp inflammation that bleaching gel generates. The rat’s molars were divided into grou...
Streptozotocin (STZ) is a compound that was originally identified in the late 1950s as an antibiotic, and currently is widely used to induce experimental diabetes mellitus. Its mechanism of action is because STZ enters Beta-cells (β-cells) via the GLUT2 transporter and accumulates intracellularly, being a glucose analogue. Although STZ has been use...
Objective:
Evaluate, in vitro, the antimicrobial activity of Psidium cattleianum leaf extracts combined with calcium hydroxide against Enterococcus faecalis and Candida albicans biofilm.
Materials and methods:
Dentin specimens obtained from extracted bovine incisors were infected during 14 days with E. faecalis ATCC 29212 and C. albicans ATCC 10...
Based on aroeira's (Myracrodruon urundeuva) antimicrobial activity and a future trend to compose intracanal medication, the aim of this study was to assess in vivo inflamatory tissue response to the extracts by edemogenic and histological analysis containing inactivated facultative and anaerobic microorganisms. For edema quantification, eighteen an...
p> Objective : The at-home bleaching technique leads to the intimate contact of the bleaching gel with gingival tissues, so this study evaluated the immediate inflammatory response, through the edemogenic test, induced by at-home bleaching gels of 10% carbamide peroxide with different desensitizing agents, the quantification of hydrogen peroxide re...
p> Objective: Evaluate, in vivo , the influence of mixing failures on endodontic sealers. Material and methods: To alveolus analysis, 80 rats were divided into Sealapex<sup>®</sup> and AH Plus<sup>®</sup> groups. Within each group, the sealer was subjected to either partial (incomplete homogenization—simulating handling failures) or total mixing (c...
The aim of this study was to evaluate edemogenic activity and subcutaneous inflammatory reaction induced by Psidium cattleianum leaf extracts associated with Ca(OH)2. Thirty male Wistar rats, split equally into three groups [aqueous extract + Ca(OH)2; ethanolic extract + Ca(OH)2; and propylene glycol + Ca(OH)2], were assessed every 3 h or 6 h (five...
p> Objective: To evaluate in vivo tissue reaction to the extract of araçá ( Psidium cattleianum ) associated with inactivated microorganisms. Material and Methods: A 0.1 mL suspension was used containing Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, Enterococcus faecalis, Peptostreptococcus micros , and Porphyromonas end...
Psidium cattleianum (PC) has been displaying inhibitory effect against a variety of microorganisms, but this effect has not yet been tested against endodontic pathogens. The aim of this study was to evaluate the antimicrobial activity and biocompatibility of the aqueous (PCAE) and hydroethanolic (PCHE) extracts from Psidium cattleianum (PC) leaves....
Objective:
This study provides an in vivo evaluation of the inflammatory response, levels of cell proliferation and apoptosis, and the presence of necrosis after dental bleaching with two concentrations of hydrogen peroxide (H2O2).
Design:
Wistar rats were divided into Control (placebo gel), BLUE (20% H2O2, 1×50min), and MAXX (35% H2O2, 3×15min)...
Objectives:
The effects of apical periodontitis (AP) and periodontal disease (PD) on organ weights in rats with diabetes mellitus (DM) were evaluated.
Design:
Eighty male rats (Rattus norvegicus albinus, Wistar) were divided into eight groups of ten: normoglycemic (N), AP, PD, AP+PD, DM, DM+AP, DM+PD, and DM+AP+PD. DM was induced by streptozotoc...
e aim of this study was to evaluate the ethanolic extract of Psidium cattleianum biocompatibility by structural and functional cell viability maintenance. Cell viability was analyzed a er 1 h, 3 h, 6 h, 10 h and 24 h of incubation by Exclusion Method with trypan blue and MTT assay, using human mononuclear cells (PBMC) and human periodontal ligament...
Obturation of the root canal system aims to fill empty spaces, promoting hermetic sealing and preventing bacterial activity in periapical tissues. This should provide optimal conditions for repair, stimulating the process of biomineralization. An endodontic sealer should be biocompatible once it is in direct contact with periapical tissues. The aim...
Enterococcus faecalis are gram positive bacteria that can mostly resist endodontic therapy, inducing persistent infection in the root canal system. Endodontic sealers with antimicrobial activity may help eliminate residual microorganisms that survive endodontic treatment. The present study aimed at comparing the antimicrobial activity of Acroseal,...
Background:
The aim of this study was to evaluate the effects of photodynamic therapy with curcumin (PDT) comparatively to 5% sodium hypochlorite (NaOCl) and saline solution on cell viability and cytokine (IL-1β and IL-6) production by mouse fibroblasts.
Methods:
Sixty seconds of pre-irradiation time with curcumin 500mg/L and Led wavelength (λ)...
Periodontal disease may be characterized by clinical symptoms such as gingival bleeding, tooth mobility, pathologic migration of supportive tissues, and loss of chewing ability. In addition, it may be classified as an inflammatory disorder of the supporting tissue of the tooth, which has different etiologies and different degrees of severity. In th...
The aim of this study was to evaluate the effect of raloxifene (RLX) during progression of periapical lesions in ovariectomized (OVX) rats.
Female Wistar rats were OVX or subjected to sham surgery and received vehicle or RLX by gavage for 90 days. The treatment groups were as follows: sham surgery and treated with vehicle (SHAM-veh), OVX and treate...
In order to evaluate late biological response of two types of filling material of deciduous teeth, calcium hydroxide and Guedes-Pinto pastes, the implantation technique in rat sockets was employed. For morphological analysis, carried out after 7 and 28 days, 48 rats had their maxillary right central incisor removed, and a polyethylene tube implant...
Primary endodontic treatment for teeth with apical periodontitis is a generally reliable and successful procedure where the objective of treatment is to eliminate intraradicular infection. However, the prognosis of retreatment cases involving a periapical lesion may be poorerarticularly when a procedural error has occurred, which increases the diff...
Aim:
To analyse the local regulatory mechanisms of osteoclastogenesis and angiogenesis during the progression of periapical lesions in female rats with oestrogen deficiency and treatment with raloxifene (RLX).
Methodology:
Female Wistar rats were distributed into groups: SHAM-veh, subjected to sham surgery and treated with a vehicle; OVX-veh, su...
Introduction
Dens invaginatus is a rare developmental anomaly that occurs during odontogenesis, with a higher prevalence in the Caucasian race and no significant sex predilection; it can be bilateral. This anomaly occurs in approximately 1.26% of the teeth, and the maxillary lateral incisor is most often affected.
Methods
This case report describe...
AimTo evaluate the influence of diabetes mellitus on the tissue response to mineral trioxide aggregate (MTA) and its ability to stimulate mineralization.Methods
Twenty-four male Wistar rats were divided into a non-diabetic control group and another with Alloxan-induced diabetes. Two polyethylene tubes, one kept empty as a control and the other cont...
Introduction
We aimed to investigate the relationship between blood profile and histologic findings in both apical periodontitis (AP) and periodontal disease (PD) associated with diabetes.
Methods
Wistar rats (N = 80) were assigned to the following 8 groups: control, AP, PD, AP associated with PD, diabetes, diabetes with AP, diabetes with PD, and...
Introduction
Recently, case reports have shown that immature teeth diagnosed with necrotic pulp and periapical periodontitis can be repaired through a regenerative endodontic procedure. True regeneration depends on the presence of stem cells in the remaining vital tissues. The aim of this study was to evaluate the histologic condition of the pulp t...
This study aimed to evaluate the influence of apical periodontitis (AP) and/or periodontal disease (PD) on serum interleukin-17 (IL-17) levels in a rat model of diabetes mellitus (DM).
Eighty male Wistar rats were divided into eight groups of ten animals each: normoglycemic, AP, PD, AP+PD, DM, DM+AP, DM+PD, and DM+AP+PD. DM was induced using strept...
Hypertension is characterized by peripheral vascular resistance that leads to blood pressure increase and several systemic changes that may negatively influence one's oral health. Thus, the aim of this study was to conduct a literature review on the influence of hypertension over oral conditions and endodontic treatment. Hypertension mainly affects...
Menopause is one of the physiological changes characterized by the end of menstrual and ovulatory cycles occuring in women in their fourth and fifth decade of life. Thereat, production of estrogen, an important hormone that acts in many physiological process of the individual such as the regulation of skeletal system, decreases. The decline in estr...
Type 1 and type 2 diabetes mellitus (DM) are characterized by hyperglycemia, due to lost or damaged insulin-producing β-cells within the pancreatic islets of Langerhans. Rodent models of DM result in hyperglycemia, arising from different forms of islet deterioration. Streptozotocin (STZ) is currently used to induce experimental DM in rodents becaus...
The aim of this study was to investigate the capacity of endodontic regenerative procedures combining an induced blood clot, platelet-rich plasma (PRP), and bone marrow aspirate (BMA) to regenerate dental pulp in canine closed-apex necrotic teeth.
Apical periodontitis was induced in 20 upper and lower premolars of 2 dogs. After biomechanical prepar...
The aim of this review was to examine current knowledge of the role of interleukin-6 (IL-6) in apical periodontitis (AP) pathogenesis as an inflammatory or pro-inflammatory cytokine. It also looked at whether IL-6 could serve as a measure for differential diagnosis or as a biomarker that can further predict the progression of bone resorption. A sys...
The combination of sodium hypochlorite (NaOCl) and chlorhexidine (CHX) yields a "precipitate potentially toxic" (PPT). The aim of this study was to evaluate the tissue response to implanted polyethylene tubes filled with PPT-soaked fibrin sponge.
Forty rats received four polyethylene tubes each; each tube was filled with fibrin sponge soaked by 2.5...
Apical surgery should be considered as the last treatment option and employed when conventional endodontic treatment does not provide the expected result. In teeth undergoing apical surgery, the type of retrograde filling material is one of the factors interfering with the repair of periapical tissues. The material in intimate contact with the peri...
Introduction: Irrigation is an important procedure during root canal treatment once it can help cleaning those areas of the root canal system not directly reached by instruments Objective: The aim of this study was to evaluate the biocompatibility and disinfection ability of silver nanoparticles dispersion in comparison to 2.5% sodium hypochlorite....
To measure glycosylated haemoglobin (HbA1c) in a diabetic model as a means of investigating apical periodontitis and periodontal disease for their effects on both blood glucose concentrations and long-term glycaemic control.
Wistar rats (n = 80) were assigned to one of eight groups (10 animals/group): control (G1), apical periodontitis (G2), period...