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This paper was adapted from Professor Carlson's presentations to the NABT National Convention in Anaheim, February 1968. The author received the Distinguished Teaching Award at UCLA, is the author of several books, and is currently working on the biography of H. J. Muller. He received his undergraduate education at New York University and his docto...
Fruit flies were used by several laboratories between 1901 and 1910 for studies of experimental evolution at Harvard, Indiana University, and Cold Spring Harbor before Thomas Hunt Morgan found his white-eyed mutation that we associate with the beginnings of the fly lab at Columbia University. The major players prior to Morgan were William Castle an...
H. J. Muller is best known for his Nobel Prize work on the induction of mutations by ionizing radiation. Geneticists are less familiar with his contributions to mutation and how he related the process of mutagenesis to the gene and distinguished gene mutations from other genetic and epigenetic events such as polyploidy, chromosome rearrangements, a...
The major findings of classical genetics were worked out between 1900 and 1920. Although those interested in human heredity knew of these findings, the techniques used in fruit flies or maize were not possible for humans, and thus, there was a delay of several decades for most of these findings to be demonstrated in humans. What turned out to be a...
At a meeting at the New School in NYC I discussed how variation was impressed on me as a TA for a comparative anatomy course. The fetal pigs differed in the size, shape, location, color, and angle of branching of major blood vessels as I went from desk to desk in the course laboratory. I discussed how that variation also existed at the level of the...
H. J. Muller (1890-1967) was unusual as a scientist because he spoke out on numerous occasions about the uses and abuses of genetics in society. In this article, I follow Muller's efforts to do so and the consequences that they had on his career, his productivity as a research scientist, and his reputation. The shifting sites of Muller's work--whic...
I don't recall using this title for an article and don't recognize the doi number used. Is there a way I can access it and see if it is an article that was published with another title?
We stand at the threshold of a new century, with the whole human
genome stretched out before us. Messages from science, the popular media,
and the stock market suggest a world of seemingly limitless opportunities
to improve human health and productivity. But at the turn of the last century,
science and society faced a similar rush to exploit human...
edited by Jan Witkowski, Cold Spring Harbor Laboratory Press, 2000. $25.00 (383 pages) ISBN 0 87969 566 8
Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and how science impacts upon all aspects of society and life.
Two experiments were conducted in order to investigate the possible effects of X-inactivation (Lyon, 1961) on female carriers of colorblindness. The results of the first experiment, like those of Grützner et al. (1976), were consistent with the prediction of the Lyon (1961) hypothesis that the retinas of female carriers are composed of mosaic patch...
The introductory science course for nonmajors can prepare students to make informed decisions about the significant biological events in their lives.