Elizabeth Ernestina Godoy-Lozano

Instituto Nacional de Salud Pública | INSP · Research Center on Infectious Diseases

Background The axolotl, Ambystoma mexicanum is a unique biological model for complete tissue regeneration. Is a neotenic endangered species and is highly susceptible to environmental stress, including infectious disease. In contrast to other amphibians, the axolotl is particularly vulnerable to certain viral infections. Like other salamanders, the...

Background The axolotl, Ambystoma mexicanum is a unique biological model for complete tissue regeneration. Is a neotenic endangered species and is highly susceptible to environmental stress, including infectious disease. In contrast to other amphibians, the axolotl is particularly vulnerable to certain viral infections. Like other salamanders, the...

Aim To evaluate the taxonomic profile of the gut microbiota using metagenomics and the association with diet-dependent childhood obesity. Methods A cross-sectional study of a subsample of 46 children was conducted. The children were classified as normal-weight, overweight, and obese according to their age and sex and the World Health Organization...

In the present study, we evaluated the biogas production from the anaerobic co-digestion of raw glycerol (RG) in combination with swine manure (SM) and the interaction of the microbial community during anaerobic co-digestion. In the same way, different RG and SM concentrations were examined in the range of 6 to 15 g L⁻¹ and 7.5 to 22.5 g L⁻¹, respe...

The Gulf of Mexico (GoM) is a particular environment that is continuously exposed to hydrocarbon compounds that may influence the microbial community composition. We carried out a metagenomic assessment of the bacterial community to get an overall view of this geographical zone. We analyzed both taxonomic and metabolic markers profiles to explain h...

Catechol 1,2 dioxygenases (C12DOs) have been studied for its ability to cleavage the benzene ring of catechol, the main intermediate in the degradation of aromatic compounds derived from aerobic degradation of hydrocarbons. Here we report the genome sequence of the marine bacterium Pseudomonas stutzeri GOM2, isolated from the southwestern Gulf of M...

The origin and function of blood IgM+IgD+CD27+ B cells is controversial, and they are considered a heterogeneous population. Previous staining of circulating B cells of healthy donors with rotavirus fluorescent virus-like particles allowed us to differentiate two subsets of IgM+IgD+CD27+: IgMhi and IgMlo B cells. Here, we confirmed this finding and...

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Indigenous bacterial populations play an important role in the restoration of crude oil-polluted marine environments. The identification and characterization of these bacteria are key in defining bioremediation strategies for the mitigation of possible future oil spills. In this work, we characterized Pseudomonas aeruginosa strain GOM1, which was i...

Marine sediments are an example of one of the most complex microbial habitats. These bacterial communities play an important role in several biogeochemical cycles in the marine ecosystem. In particular, the Gulf of Mexico has a ubiquitous concentration of hydrocarbons in its sediments, representing a very interesting niche to explore. Additionally,...

The effect of extrusion process in aquafeeds for juvenile totoaba (Totoaba macdonaldi) on the microbiome diversity from four different intestinal sections and overall growth performance was evaluated. The extrusion process clearly improved the protein efficiency ratio (PER) and the apparent digestibility coefficient (ADC) compared to the modified e...

Metagenomics research has recently thrived due to DNA sequencing technologies improvement, driving the emergence of new analysis tools and the growth of taxonomic databases. However, there is no all-purpose strategy that can guarantee the best result for a given project and there are several combinations of software, parameters and databases that c...

Background Chagas disease is a parasitic infection caused by Trypanosoma cruzi. It is an important public health problem affecting around seven to eight million people in the Americas. A large number of hematophagous triatomine insect species, occupying diverse natural and human-modified ecological niches transmit this disease. Triatomines are long...

El desarrollo de material didáctico para la enseñanza de la bioinformática es de vital importancia para darle difusión al alcance de las técnicas metagenómicas y despertar la curiosidad en aquellos que todavía no deciden a que se dedicarán en el futuro. En este artículo se describen los fundamentos de como se lleva a cabo la anotación taxonómica de...

Introducción Las enfermedades pulmonares son uno de los mayores problemas en salud pública y son la causa de aproximadamente una de cada seis muertes en el mundo [1]. Estimaciones de la Organización Mundial de la Salud en 2005, posicionaron a la Enfermedad Pulmonar Obstructiva Crónica (EPOC) como la quinta causa principal de muerte a nivel mundial...

The study of human B cell response to dengue virus (DENV) infection is critical to understand serotype-specific protection and the cross-reactive sub-neutralizing response. Whereas the first is beneficial and thus represents the ultimate goal of vaccination, the latter has been implicated in the development of severe disease, which occurs in a smal...

Background: Despite the potential to produce antibodies that can neutralize different virus (heterotypic neutralization), there is no knowledge of why vaccination against influenza induces protection predominantly against the utilized viral strains (homotypic response). Identification of structural patterns of the B cell repertoire associated to h...

The B cell antigen receptor repertoire is highly diverse and constantly modified by clonal selection. High-throughput DNA sequencing (HTS) of the lymphocyte repertoire (Rep-Seq) represents a promising technology to explore such diversity ex-vivo and assist in the identification of antigen-specific antibodies based on molecular signatures of clonal...

High-throughput sequencing of the antibody repertoire is enabling a thorough analysis of B cell diversity and clonal selection, which may improve the novel antibody discovery process. Theoretically, an adequate bioinformatic analysis could allow identification of candidate antigen-specific antibodies, requiring their recombinant production for expe...

To determine the contribution of influenza and respiratory syncytial virus (RSV) as the cause of lower respiratory tract infection (LRTI) associated hospitalizations during the first year of the influenza A(H1N1) 2009 pandemic and to assess the severity of illness during the second pandemic wave. Patients admitted with LRTI from April 2009 through...

Palabras Clave: Virus de influenza A (H1N1), pandemia, caracterización genómica, enfermedades infecciosas emergentes.