About
15
Publications
8,644
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
163
Citations
Introduction
๐ Passionate PhD Researcher | Cancer Therapy | Drug Delivery | Biotechnology
I am an experienced PhD researcher with a strong background in biomedical sciences, pharmaceuticals, and biotechnology. My research focuses on bioactive compounds from plants for cancer therapy, bridging natural medicine with cutting-edge treatment strategies.
โ Cell culture & apoptosis assays
โ Drug delivery & nanomedicine
โ PCR & Western blotting
โ Advanced microscopy & data analysis
โ Pharmacology & chemistry
Current institution
Education
November 2013 - November 2019
September 2009 - November 2012
University of Malaya
Field of study
- Biotechnology
October 2004 - September 2008
Publications
Publications (15)
Article History Interest in and awareness of health attributes by natural resources such as herbs, spices, and fruits have resulted in increased consumption of natural products for a safe and effective resolution for illness and also promoting good health. Plants are rich in diverse chemical substances, including polyphenols, flavonoids, and xantho...
There are an increasing number of fermented beverage using herbal extract as a natural ingredient. The growth of bacteria in four plant water extract (Lycium barbarum, Psidium guajava, Momordica grosvenori, and Garcinia mongostana) as measured by the increase in turbidity of MRS and M17 growth medium containing Lactobacillus spp. and Streptococcus...
Yogurt production with starter culture at 41 ยฐC in the presence of plant water extracts ( Momordica grosvenori , Psidium guajava , Lycium barbarum or Garcinia mangostana ) were studied to examine the effects on acidification, physicochemical properties, microbial growth, proteolytic activity, and exopolysaccharide (EPS) content. All plant-based yog...
Background
Tea (Camellia sinensis) is one of the most consumed beverages in the world. White tea is an unfermented tea made from young tea leaves or unopened buds.
Methods
The in vitro antiproliferation assay and in vivo Chemopreventive effects of white tea extract (WTE) using azoxymethane (AOM) induced aberrant crypt foci (ACF) in rats was assess...
The authors have withdrawn this preprint due to author disagreement.
Background
The effect of delivered bromine vapor and also bromine substitutions are shown to play an important role in anti-inflammatory activity. The present study encompasses a broad in vivo study to size up healing activity of a novel dibromide substituted Schiff based compound against cutaneous wound model in Sprague Dawley (SD) rats.
Methodol...
Background
Brucea javanica (L.) Merr. is a plant from the genus Brucea, which is used in local traditional medicine to treat various diseases. Recent studies revealed an impressive anticancer efficiency of B. javanica extract in different types of cancer cells.
Purpose
In this study, we have investigated the cytotoxic effects of the B. javanica he...
Quinazoline is an aromatic bicyclic compound exhibiting several pharmaceutical and biological activities. This study was conducted to investigate the potential wound healing properties of synthetic quinazoline compound (SQC) on experimental rats. The toxicity of SQC was determined by MTT cell proliferation assay. The healing effect of SQC was asses...
Brucea javanica (L.) Merr. is a well-known plant in Chinese System of Medicine. Its fruits and seeds have been reported to possess curative properties against various ailments. The chemical constituents and biological activity of this plant have been an interesting area in plant and chemistry medicine. The aim of this study is to evaluate the antip...
Colorectal cancer is the third most common form of cancer affecting both men and women around the world. The chemical and biological studies of heterocyclic compounds have been an interesting area in pharmaceutical and medicinal chemistry. A new synthetic compound namely 2-(1,1-dimethyl-1H-benzo[e]indol-2-yl)-3-((2-hydroxyphenyl)amino)acrylaldehyde...
Assess the antiproliferative effects of the B. javanica ethanolic extract (BJEE) against colon cancer cell (HCT-116) and its possible mechanism of action was investigated.
Cibotium barometz is a pharmaceutical plant customarily used in traditional medicine in Malaysia for the treatment of different diseases, such as gastric ulcer. The gastroprotective effect of C. barometz leaves against ethanol-induced gastric hemorrhagic abrasions in Sprague Dawley rats has been evaluated in terms of medicinal properties. Seven gro...
Background:
Colorectal cancer is the third most common form of cancer in both men and women around the world. The chemistry and biological study of heterocyclic compounds have been an interesting area for a long time in pharmaceutical and medicinal chemistry.
Methods:
A new synthetic compound, 2-(1,1-Dimethyl-1,3-dihydro-benzo[e]indol-2-ylidene)...
Main objective: To evaluate the cytotoxicity effects of Brucea javanica extract on the colorectal cancer cells (HCT-116).
Specific objectives:
To obtain alcoholic extraction from Brucea Javanica
To study apoptotic effects of Brucea javanica extract on human colorectal cancer cells (HCT-116)
To see toxicity effects of Brucea javanica extract
To det...