Elba Mauriz

Elba Mauriz
Universidad de León | UNILEON · Department of Nursing and Physiotheraphy

PhD

About

38
Publications
7,015
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1,344
Citations
Introduction
Elba Mauriz currently works at the Department of Nursing and Physiotherapy, Universidad de León. Elba does research in Biosensors and analytical applications. Their most recent publication is 'Recent Progress in Plasmonic Biosensing Schemes for Virus Detection'.
Additional affiliations
October 2016 - November 2019
Universidad de León
Position
  • Professor (Assistant)

Publications

Publications (38)
Article
Full-text available
The emerging risk of viral diseases has triggered the search for preventive and therapeutic agents. Since the beginning of the COVID-19 pandemic, greater efforts have been devoted to investigating virus entry mechanisms into host cells. The feasibility of plasmonic sensing technologies for screening interactions of small molecules in real time, whi...
Chapter
Early identification of clinical biomarkers is strongly demanded for the rapid diagnosis and treatment of disease conditions. Over the last few decades, plasmonic biosensors have attracted the interest of the biomedical field due to their simplicity and functionality. The optical properties of plasmonic materials have enabled the design of biosensi...
Article
Full-text available
Psychophysiological stress can affect the cognitive response and effective learning of students during medical simulation practices. This study aimed to explore the effect of psychophysiological stress and socio-emotional competencies on clinical performance during a simulation experience. A pre-test/post-test design was used to assess physiologica...
Article
Full-text available
The rapid spread of epidemic diseases (i.e., coronavirus disease 2019 (COVID-19)) has contributed to focus global attention on the diagnosis of medical conditions by ultrasensitive detection methods. To overcome this challenge, increasing efforts have been driven towards the development of single-molecule analytical platforms. In this context, rece...
Article
Full-text available
Colorimetric analysis has become of great importance in recent years to improve the operationalization of plasmonic-based biosensors. The unique properties of nanomaterials have enabled the development of a variety of plasmonics applications on the basis of the colorimetric sensing provided by metal nanoparticles. In particular, the extinction of l...
Conference Paper
Full-text available
Introduction: Multiple sclerosis (MS) is an inflammatory disease resulting in demyelination and neuronal degeneration. Among the multiple risk factors that contribute to MS progression, malnutrition plays a pivotal role in the impact and quality of life of MS patients. Objectives: The aim of this study was to evaluate the effect of nutritional stat...
Article
Full-text available
The global burden of coronavirus disease 2019 (COVID-19) to public health and global economy has stressed the need for rapid and simple diagnostic methods. From this perspective, plasmonic-based biosensing can manage the threat of infectious diseases by providing timely virus monitoring. In recent years, many plasmonics’ platforms have embraced the...
Article
Full-text available
The extent of anxiety and psychological stress can impact upon the optimal performance of simulation-based practices. The current study investigates the association between differences in skin temperature and perceived anxiety by under- (n = 21) and post-graduate (n = 19) nursing students undertaking a cardiopulmonary resuscitation (CPR) training....
Article
Full-text available
The monitoring of biomarkers in body fluids provides valuable prognostic information regarding disease onset and progression. Most biosensing approaches use noninvasive screening tools and are conducted in order to improve early clinical diagnosis. However, biofouling of the sensing surface may disturb the quantification of circulating biomarkers i...
Conference Paper
Full-text available
Providing reliable systems to assess ventilation outcomes in simulation-based scenarios is paramount to improve the performance during cardiopulmonary resuscitation (CPR) in real situations. The aim of this study is to investigate the reliability of infrared thermography (IRT) in monitoring the quality of resuscitative breaths in undergraduate nurs...
Article
Biomarkers are unquestionable biological indicators for diagnosis and therapeutic interventions providing appropriate classification of a wide range of health disorders and risk factors. Nonetheless, detection and quantification of biomarkers need...
Article
Introduction: Introduction: gastronomy and eating habits are key factors that determine a population's health and nutritional status. The geographical and climatic peculiarities of Castilla y León (CyL) contribute to the development of its cultural and gastronomic wealth. Objectives: to evaluate the gastronomic characteristics of CyL and assess th...
Article
Full-text available
Introduction: Surgical safety is a public health concern worldwide. The attitudes and perceptions of the surgical team regarding to the safety of the patient are associated to the safety climate and the prevalence of adverse events. Objective: To evaluate the safety climate perceived by operating room nurses from several Hospitals. Method: This wor...
Article
La evaluación formativa permite obtener información sobre la progresión del aprendizaje y es un elemento esencial para evaluar competencias. Este trabajo describe la aplicación de una práctica de simulación para adquirir la competencia clínica de “inmovilización cervical: manejo del collarín cervical” en estudiantes de segundo curso del grado de En...
Article
Surface biofunctionalization, including chemical activation and attachment of the bioreceptor, is an essential step to provide reliable detection of biomolecular binding events monitored by Surface Plasmon Resonance (SPR), the most employed optical biosensor, and other biosensor techniques. Recent progress in the area of immobilization procedures a...
Article
Full-text available
Introduction: Inflammation is one of the main contributory factors to the etiopathogenesis of multiple sclerosis (MS). Dietary interventions with Lipia citriadora (lemon verbena) extracts have been proved to be effective in the prevention of inflammatory diseases. Objectives: The aim of this study is to evaluate the effect of lemon verbena suppleme...
Article
Full-text available
Surface plasmon resonance (SPR) monitoring of biorecognition events at intracellular levels is a valuable tool for studying the angiogenic response of carcinoma living cells during tumor growth and proliferation. We report here a comparative study of two different strategies to detect human hepatoma cell interactions between transmembrane vascular...
Article
Full-text available
Introduction: Multiple sclerosis (MS) treatment options are primarily limited to immunomodulatory therapies in MS non-progressive forms. Nutrition intervention studies suggest that diet may be considered as a complementary treatment to control disease progression. Therefore, dietary intervention may help to improve wellness and ameliorate symptoms...
Article
Full-text available
A surface plasmon resonance (SPR) immunoassay for on-line detection of the strobilurin fungicide pyraclostrobin in untreated fruit juices is presented. The analysis of pyraclostrobin residues is accomplished in apple, grape, and cranberry samples by monitoring the recognition events occurring separately in a two-channel home-made SPR biosensor. Cov...
Article
High quality local varieties of blue-veined cheese are made in the villages of the valleys of Cabrales, Valdeón and Bejes-Tresviso in North Spain. Penicillium roqueforti strains have been isolated from each of those blue cheeses and compared with the collection strain P. roqueforti CECT 2905 (ATCC 10110) and a strain 'Valdeón-industrial' used for l...
Article
Full-text available
We have studied the role of the pga1 gene of Penicillium chrysogenum, encoding the alpha subunit of a heterotrimeric G protein, in secondary metabolite production. The dominant activating pga1(G42R) mutation caused an increase in the production of the three secondary metabolites penicillin, the yellow pigment chrysogenin and the mycotoxin roquefort...
Article
The biosynthesis of the beta-lactam antibiotic penicillin is an excellent model for the study of secondary metabolites produced by filamentous fungi due to the good background knowledge on the biochemistry and molecular genetics of the beta-lactam producing microorganisms. The three genes (pcbAB, pcbC, penDE) encoding enzymes of the penicillin path...
Article
Full-text available
NRPSs (non-ribosomal peptide synthetases) and PKSs (polyketide synthases) require post-translational phosphopantetheinylation to become active. This reaction is catalysed by a PPTase (4'-phosphopantetheinyl transferase). The ppt gene of Penicillium chrysogenum, encoding a protein that shares 50% similarity with the stand-alone large PPTases, has be...
Chapter
For the development of field sensor systems with enough sensitivity and selectivity we develop photonic biosensors based on evanescent wave detection. Two technologies have been implemented in parallel: a plasmonic sensor for multianalyte real-time evaluation and an integrated optical nanosensor fabricated with silicon microelectronics technology....
Article
A new immunoassay for continuously monitoring atrazine in water has been developed. It uses a portable biosensor platform based on surface plasmon resonance (SPR) technology. This immunoassay is based on the binding inhibition format with purified polyclonal antibodies, with the analyte derivative covalently immobilized on a gold sensor surface. An...
Article
Full-text available
An immunochemical method for the analysis of 3,5,6-trichloro-2-pyridinol (TCP), a major urinary metabolite of chlorpyrifos, is developed using a surface plasmon resonance (SPR)-based biosensor. The stability of the assay was assessed by covalently linking the analyte derivative to a thin, gold-modified sensor surface. For optimization of analyte de...
Article
Full-text available
Multi-analyte detection of environmentally relevant pesticides is performed by using a two-channelled surface plasmon resonance (SPR) biosensor. The special design of the SPR instrument allows the determination of several analytes (DDT, chlorpyrifos and carbaryl) via different immobilization formats. First, simultaneous pesticide monitoring is poss...
Article
A surface plasmon resonance (SPR) based immunosensor has been developed for the monitoring of environmentally persistent pollutants like DDT, its metabolites and analogues in real water samples. A reusable immunosurface is provided via the covalent attachment of the analyte derivative to a self-assembled alkanethiol monolayer formed onto the SPR go...
Article
On-line determination of pollutants within the two main types of cholinesterase inhibitors: organophosphate pesticide chlorpyrifos and carbaryl, a carbamate insecticide, is carried out by a new developed surface plasmon resonance (SPR) optical immunosensor. Two different immunoassay approaches have been tested to detect the target analytes by using...
Article
The analysis of carbaryl in natural water samples was accomplished using a portable immunosensor based on surface plasmon resonance (SPR) technology. The assay was based on a binding inhibition immunoassay format with the analyte derivative covalently immobilized on the sensor surface. An alkanethiol self-assembled monolayer (SAM) was formed onto t...
Article
A portable surface plasmon resonance (SPR) optical biosensor device is described as a direct immunosensing system to determine organic pollutants in natural water samples. Monitoring of organochlorine (DDT), organophosphorus (chlorpyrifos) and carbamate (carbaryl) compounds within the concentration levels stipulated by the European legislation, can...
Article
Continuous monitoring of the organophosphate pesticide chlorpyrifos in real water samples has been performed using a portable surface plasmon resonance (SPR) immunosensor. The immunoassay was based on a binding inhibition test by using the covalent immobilization of an analyte derivative onto the gold-coated sensing surface. Sensor reusability was...
Chapter
The present article reviews three different optical biosensing mechanisms that can be implemented in a multibiosensor technology platform: surface plasmon resonance, magnetooptical surface plasmon resonance and optoelectronic biosensing (evanescent wave detection) using integrated Mach-Zehnder interferometer devices. In the last case, the use of st...
Article
Full-text available
The present article reviews two different optical biosensing mechanisms (based on evanescent wave detection) that can be implemented in a multibiosensor technology platform: surface plasmon resonance, and optoelectronic biosensing using integrated Mach-Zehnder interferometer devices. In the last case, the use of standard silicon microelectronics te...

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