Edward Archer

Edward Archer
Macquarie University

PhD

About

27
Publications
5,869
Reads
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624
Citations
Citations since 2016
23 Research Items
617 Citations
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2016201720182019202020212022050100150
Additional affiliations
January 2015 - present
Stellenbosch University
Position
  • Academic Researcher
Description
  • The research contains the detection of endocrine disruption and organic pollutants at selected wastewater treatment works (WWTWs) managed by ERWAT.
February 2014 - November 2017
Stellenbosch University
Position
  • Research Assistant
January 2013 - present
Stellenbosch University
Position
  • Environmental Toxicology Consultant
Description
  • We offer consultation to educational institutions and the industry for the evaluation of endocrine disrupting contaminants (EDCs) in aquatic organisms and environmental waters by using in vitro bioassays and animal biomarkers.
Education
February 2015 - March 2018
Stellenbosch University
Field of study
  • Environmental Microbiology and Toxicology
January 2011 - March 2014
Stellenbosch University
Field of study
  • Zoology

Publications

Publications (27)
Article
Full-text available
A large number of emerging contaminants (ECs) are known to persist in surface waters, and create pressure on wastewater treatment works (WWTW) for their effective removal. Although a large database for the levels of these pollutants in water systems exist globally, there is still a lack in the correlation of the levels of these pollutants with poss...
Article
The current study is aimed to introduce a wastewater-based epidemiology (WBE) approach for the first time on the African continent where substance abuse data is limited. The study included the quantification of several drugs of abuse (DOA) in raw wastewater samples. Quantification of urinary metabolites as drug target residues (DTR), as well as ena...
Article
This study evaluated the occurrence and fate of fourteen contaminants of emerging concern (CECs) at two South African wastewater treatment works (WWTW). Daily loads of the drug targets were calculated in the aqueous phase of influent-and effluent wastewater to evaluate their fate at the treatment works, along with population-normalised daily loads...
Article
Full-text available
The study evaluated the presence and fate of various contaminants of emerging concern (CECs) from a South African wastewater treatment works (WWTW) and surface waters located around an urban setting. A total of 45 CECs were quantified from nine sampling locations over an 11-month period. Daily loads (g/day) of the target analytes in the WWTW showed...
Article
Full-text available
The current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic capacity is limited in defined communities, posing a challenge in tracking and tracing new infections. Monitoring student residences, which are considered infection hotspots, with targeted wastewater surveillance is crucial. This study evaluated the efficacy of SARS...
Article
The global COVID-19 pandemic has highlighted the need for stronger health systems, and the potential role of networks in this strengthening. In the early phase of the pandemic, wastewater surveillance as a predictive and monitoring tool for COVID-19 was identified internationally. This realisation alerted researchers in South Africa, who through va...
Article
Full-text available
Chemical pollution (including chemicals of emerging concern – CECs) continues to gain increasing attention as a global threat to human health and the environment, with numerous reports on the adverse and sometimes devastating effects upon ecosystems the presence of these chemicals can have. Whilst many studies have investigated presence of CECs in...
Article
Full-text available
The results from this study are of importance as they fill a gap in the data available on environmental AMR in South Africa to date. This study was done in parallel with co-investigators focusing on the prevalence of various antimicrobials at the same sites selected in our study, verifying that the sites that are influenced by informal settlements...
Article
Full-text available
Antimicrobial agent (AA) usage, excretion, and persistence are all important factors in association with the occurrence and dissemination of antimicrobial resistance. Urban water profiling was utilised in the Eerste River catchment (South Africa) to establish AA usage in a region where comprehensive prescription records were not readily available a...
Article
Full-text available
With the advent of the SARS-CoV-2 pandemic, Wastewater-Based Epidemiology (WBE) has been applied to track community infection in cities worldwide and has proven succesful as an early warning system for identification of hotspots and changingprevalence of infections (both symptomatic and asymptomatic) at a city or sub-city level. Wastewater is only...
Thesis
Full-text available
Global surface waters are increasingly shown to be contaminated by anthropogenic chemical pollutants which, in turn exert potential lethal- and sub-lethal toxicity risks to the aquatic environment and humans. In particular, pollutants which are able to modulate endocrine system pathways, known as endocrine disrupting contaminants (EDCs) are of an e...
Preprint
Antibiotic usage, excretion, and persistence are all important factors in association with the occurrence and dissemination of antimicrobial resistance. Urban water profiling was utilised in the Eerste River catchment (South Africa) to establish antibiotic usage in a catchment where comprehensive prescription records were not readily available and...
Preprint
Antibiotic usage, excretion, and persistence are all important factors in association with the occurrence and dissemination of antimicrobial resistance. Urban water profiling was utilised in the Eerste River catchment (South Africa) to establish antibiotic usage in a catchment where comprehensive prescription records were not readily available and...
Article
Full-text available
Thyroid hormones play critical roles in body growth and development as well as reproduction. They also influence the activities of a wider variety of tissues and biological functions, such as osmoregulation, metabolism, and especially metamorphosis in organisms, such as frogs. These complex activities of thyroid hormones are prone to disruption by...
Article
Full-text available
Recent studies have shown that the detection of SARS-CoV-2 genetic material in wastewater may provide the basis for a surveillance system to track the environmental dissemination of this virus in communities. An effective wastewater-based epidemiology (WBE) system may prove critical in South Africa (SA), where health systems infrastructure, testing...
Chapter
This chapter will discuss the current state of knowledge of endocrine-disrupting contaminant (EDC) research in South Africa. As with most developing countries, South Africa faces rapid urbanization and population growth that places severe strain on food security and production, which further contribute toward the release of EDCs in the natural envi...
Article
Full-text available
Institutions of Higher Education have grappled with the predicament of first-year success and epistemological access for years. Recently, a study employed Legitimation Code Theory (LCT) to elucidate why students who performed relatively well in high school biology struggled with the subject in first-year. This study shed valuable light on this prob...
Conference Paper
Full-text available
Natural/synthetic steroid hormones and many organic pollutants persisting through wastewater treatment works (WWTWs) are of particular concern for their endocrine-disrupting activities observed in receiving surface waters. Apart from the demonstrated presence of estrogen-and estrogen-mimicking compounds in surface waters, antagonistic (anti-estroge...
Article
Full-text available
Globally, water resources are under constant threat of being polluted by a diverse range of man-made chemicals, and South Africa is no exception. These contaminants can have detrimental effects on both human and wildlife health. It is increasingly evident that several chemicals may modulate endocrine system pathways in vertebrate species, and these...
Poster
Full-text available
Substance abuse is of an ongoing concern in South Africa, with limited sources to estimate the use of illicit and pharmaceutical substances in communities. Wastewater-based epidemiology (WBE) allows for a community-based estimation of substance abuse by detecting the loads of illicit drugs and other drugs of abuse (DOA) within wastewater coming fro...
Article
Full-text available
Although it is known that environmental chemicals can affect the oestrogenic system, far less attention has been paid to chemicals interacting with the androgen receptor (AR). Pesticides, particularly fungicides, have been shown to competitively bind or affect expression of the AR in an inhibiting manner. Few studies have addressed anti-androgenic...
Article
Full-text available
Cetaceans, occupying the top levels in marine food chains, are vulnerable to elevated levels of potentially toxic trace elements, such as aluminum (Al), mercury (Hg) and nickel (Ni). Negative effects associated with these toxic metals include infection by opportunistic microbial invaders. To corroborate the link between the presence of cutaneous fu...
Technical Report
Full-text available
Various agricultural pesticides have been shown to modulate reproductive- and thyroid endocrine systems in aquatic vertebrates through various pathways. However, the link between laboratory- and field studies are seldom drawn. The study included a tiered approach to investigate the potential of agricultural pesticides to modulate vertebrate endocri...
Thesis
Full-text available
Endocrine disrupting contaminants (EDCs) coming from households, industrial parks, wastewater (sewage) treatment and agricultural areas have been shown to pollute our freshwater systems. These contaminants may disrupt early development and reproductive systems in freshwater organisms (fish, frogs and crocodile species) as well as humans. Agricultur...

Network

Cited By

Projects

Projects (6)
Project
The network group consists of collaborating laboratories, waste water treatment plants and public health officials to monitor and quantify the loads of SARS-CoV-2 RNA in sewage using a wastewater-based epidemiology approach. A distributed network involving multiple laboratories will allow expanded geographic sampling with a central data hub. Such information will assist policy-makers to determine trends in infection rates in various geographic areas of the country and may guide appropriate public health interventions.
Project
ReNEW consists of a multi-disciplinary research team from the engineering, natural- and social sciences from two academic institutions (University of Bath, UK and Stellenbosch University, South Africa). We are proposing an innovative solution to current problems with rapidly identifying and responding to deteriorating public health and environmental conditions in fast developing urban environments in LMIC countries, aiming to manage risks to public and environmental health relating to urbanisation, population growth, lack of infrastructure and the overarching challenge of climate change. We aim to establish a cutting-edge, interdisciplinary research capability for real-time community-wide diagnostics and tuneable multi-hazard public health early warning system (EWS) with the ultimate goal of strengthening communities’ resilience. We will do this through a focus on urban water as water from urban dwellings reflects the health status of a population and surrounding environment as it pools the endo- & exogenous products of that population.
Project
Here we propose a novel supplemental low-resource approach for broad community-wide surveillance of SARS-CoV-2 infection prevalence. We aim for a real-time Covid-19 risk prediction platform for community-wide diagnostics via wastewater-based epidemiology. Disease markers present in domestic wastewater can reveal the health status of contributing population, and we propose that this includes the infection prevalence by SARS-CoV-2. Real-time spatiotemporal estimation of this novel coronavirus in urban water across several sites in South Africa (Cape Town) and Nigeria (Lagos) will provide a broad picture of community infection prevalence, even for asymptomatic cases, as well as the level of acquired immunity, thus identifying hotspots for priority testing, contact-tracing and quarantine and will provide more accurate projections of the spread of the virus and the infection fatality rate. As communities contribute directly to wastewater, we will be able to estimate true infection rate at the community level, including also asymptomatic and pre-symptomatic people. The virus loading levels will be used to establish status and time trends. This would enable rapid identification of hot spots for management via targeted intervention measures and potentially support important decisions regarding entry into and exit from ‘lockdown’ periods as well as focussed screening of selected communities.