Edmond Sanganyado

Edmond Sanganyado
Northumbria University · Department of Chemical and Forensic Sciences

PhD Environmental Toxicology
Investigating the chemodynamics and ecotoxicology of legacy and emerging POPs in marine ecosystems.

About

101
Publications
149,240
Reads
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1,500
Citations
Introduction
I am interested in understanding the fate and transport of emerging contaminants in the aquatic environment. My overall research goal is to develop safe and sustainable solutions for mitigating pollution in freshwater systems.
Additional affiliations
July 2019 - February 2022
Shantou University
Position
  • Professor (Associate)
March 2017 - June 2019
Shantou University
Position
  • PostDoc Position
October 2016 - March 2017
National University of Science and Technology, Bulawayo
Position
  • Lecturer
Education
June 2021 - December 2021
Stellenbosch University
Field of study
  • CREST Online Training for Doctoral Supervisors
January 2018 - September 2018
Falmouth University
Field of study
  • Higher Education
September 2011 - August 2016
University of California, Riverside
Field of study
  • Environmental Toxicology

Publications

Publications (101)
Article
More than 50% of pharmaceuticals in current use are chiral compounds. Enantiomers of the same pharmaceutical have identical physicochemical properties, but may exhibit differences in pharmacokinetics, pharmacodynamics and toxicity. The advancement in separation and detection methods has made it possible to analyze trace amounts of chiral compounds...
Article
Full-text available
In recent years, there has been a growing interest on the occurrence of antibiotic resistant bacteria (ARB) and antibiotic resistant genes (ARGs) in treated and untreated drinking water. ARB and ARGs pose a public health concern when they transfer antibiotic resistance (AR) to human pathogens. However, it is still unclear whether the presence of en...
Article
The assumption that only biological processes are enantioselective introduces challenges in the reliability of enantioselective analysis as a tool for discriminating biotic and abiotic processes in the environmental fate of chiral pollutants. Enantioselectivity does not depend on the nature of the fate process a chiral contaminant undergoes but on...
Article
Full-text available
As apex predators, marine mammals play a key role in maintaining community structure and functioning in marine ecosystems. Hence, a decline in marine mammal populations may have negative effects on the ecosystem function and services. The discharge of anthropogenic chemicals and particles (micropollutants) into the marine environment threatens the...
Article
The deep sea - an oceanic layer below 200 m depths – has important global biogeochemical and nutrient cycling functions. It also receives organic pollutants from anthropogenic sources, which threatens the ecological function of the deep sea. In this Review, critically examined data on the distribution of organic pollutants in the deep sea to outlin...
Article
The performance of different suspended fillers (zeolite, drinking water treatment residual, biochar, woodchip and stereo-elastic packing) and their combinations in treating municipal wastewater in ecological floating beds (Eco-FBs) planted with Myriophyllum aquaticum was assessed. Six sets of enhanced Eco-FBs were developed to assess the individual...
Article
The discharge of antibiotics and metals in estuaries is of great concern since they threaten microbial communities that are critical for maintaining ecosystem function. To understand single and combined effects of norfloxacin (0–20 μg g⁻¹) and copper (40 μg g⁻¹) on microbial ecology in estuaries, we evaluated changes in bacteria population, inhibit...
Article
Mangroves are highly dynamic ecosystems that offer important services such as maintaining biodiversity, filtering pollutants, and providing habitats for fishes. We investigated the uptake and accumulation of nutrients and potentially toxic elements in mangrove plants and fish to better understand the role of mangrove restoration in maintaining mang...
Article
Assessing the structure and composition of gut microbiota of sentinel species such as spotted seals (Phoca largha) is a potential tool for assessing the health of the marine mammals and their habitats. However, the link between the host microbiome and their habitat is poorly understood. In this study, microbial communities in the habitat (sea ice a...
Article
Full-text available
Background: Sexually transmitted infections (STIs) are a major public health challenge, particularly in developing countries where the health infrastructure is often poor. Despite having a number of interventions in Beitbridge (such as the 24-h wellness centre), Zimbabwe, the incidence and prevalence of STIs is increasing. Objectives: This study,...
Preprint
Sustainable Development Goal 9 encourages building resilient infrastructure, fostering innovation, and promoting sustainable infrastructure by significantly increasing the number of researchers. Using Zimbabwe as a typical developing country, we analyzed ten continental, five regional, five national, and 32 sectoral science policies on their commit...
Article
Anthropogenic activities can adversely impact biogeochemical processes essential for maintaining ecosystem health in semi-enclosed bays. However, the influence of anthropogenic contaminants such as potentially toxic elements on microbial communities that regulate biogeochemical cycles in semi-enclosed bays is poorly understood. We determined the co...
Article
Full-text available
The gut microbiome is a unique marker for cetaceans’ health status, and the microbiome composition of their skin wounds can indicate a potential infection from their habitat. Our study provides the first comparative analysis of the microbial communities from gut regions and skin wounds of an individual Indo-Pacific finless porpoise (Neophocaena pho...
Article
Full-text available
The outbreak of the human coronavirus disease 2019 (COVID-19) has induced an unprecedented increase in the use of several old and repurposed therapeutic drugs such as veterinary medicines, e.g. ivermectin, nonsteroidal anti-inflammatory drugs, protein and peptide therapeutics, disease-modifying anti-rheumatic drugs and antimalarial drugs, antiretro...
Article
The increased use of neonicotinoid insecticides in aquatic environments poses a significant threat to non-target freshwater species. However, the existing water quality guidelines (WQGs) for neonicotinoids mainly focus on imidacloprid, and only a few authoritative institutions have established WQGs for other neonicotinoids. There is a critical need...
Article
Hydroxylated polybrominated diphenyl ethers (OH-BDEs) are major transformation products of PBDEs that readily bioaccumulate in the marine food web. Although 6-OH-BDE-47 is frequently and abundantly detected in cetaceans, its potential toxic effects are largely unknown. We explored the toxicological pathways and mechanisms of OH-BDEs by exposing pyg...
Chapter
Full-text available
Traditional environmental monitoring and characterization approaches are inadequate for addressing the health and safety issues of the emerging contaminants due to the enormous number of synthetic substances in use today. Advances in chemical and biological analysis, particularly suspect and nontarget screening, effect-directed analysis, high throu...
Chapter
Full-text available
The presence of emerging pollutants in aquatic systems such as rivers, lakes, groundwater, glaciers, wetlands, the ocean poses significant risk to human and environmental health. Emerging pollutants are natural or synthetic chemicals, microorganisms or particles that are generally not monitored in the environment. Several studies have detected vari...
Article
Microplastic pollution is a ubiquitous and emerging environmental and public health concern in Africa due to increased plastic production, product and waste importation, and usage. While studies on the environmental monitoring and characterization of microplastics demonstrated the urgent need for a drastic reduction in plastic waste generation, the...
Article
We investigated the tissue distribution, trophic transfer, and ecological risk of 13 trace elements in 26 East Asian finless porpoises (Neophocaena asiaeorientalis sunameri), an endangered species found in the Liaodong Bay and the north Yellow Sea. All the investigated trace elements were detected in the tissue and food web of the East Asian finles...
Article
Full-text available
Background: Sexually transmitted infections are a major public health challenge, particularly in developing countries where the health infrastructure is often poor. Despite having a number of interventions in Beitbridge (such as the 24-hour wellness centre), Zimbabwe, the incidence and prevalence of sexually transmitted infections is increasing. Th...
Article
Constructed wetlands (CWs) are nature-based solutions for treating domestic and livestock wastewater which may contain residual antibiotics concentration. Antibiotics may exert selection pressure on wetland’s microbes, thereby increasing the global antibiotics resistance problems. This review critically examined the chemodynamics of antibiotics and...
Article
Semi-enclosed bays are used for critical economic activities such as ports, aquaculture, and human settlement due to their topography and ocean connectivity. However, the role of these geomorphological characteristics on the accumulation of chlorinated organic pollutants in semi-enclosed bays is poorly understood. We investigated the spatiotemporal...
Article
Developing nations should invest in research and development spending and stimulate the private sector to spend more on science, technology, and innovation.
Chapter
Full-text available
Cetaceans are aquatic mammals, large-headed, hairless, and torpedo-shaped mammals with a complex stomach comprising of at least four chambers. There are 90 species belonging to the order Cetacea; examples include dolphins, porpoises, and whales (Smith et al. 2003). Cetacean health encompasses the sum of all biological, social, and environmental in...
Technical Report
Full-text available
In response to the Manpower Planning and Development Amendment Act of 2020 and the Centre for Education, Innovation Research and Development Bill of 2020 to promote science, technology, and innovation, the Zimbabwe Young Academy of Sciences convened the Research Excellence Initiative to develop policy recommendations that can guide in ensuring the...
Article
In recent years, interest in the use of microalgae as cell factories to produce biopharmaceutical glycoproteins increased observably. Microalgae often produce biopharmaceutical glycoproteins through post-translational modification of proteins via N-glycosylation. The biophysical properties of biopharmaceutical glycoproteins such as folding, stabili...
Article
Full-text available
Understanding the occurrence, behavior, and fate of potentially toxic elements (PTEs) in the substrate-mushroom-human nexus is critical for assessing and mitigating their human health risks. In this review, we (1) summarized the nature, sources, and biogeochemical behavior of PTEs in the substrate-mushroom systems; (2) discussed the occurrence, exp...
Article
Full-text available
Indo-Pacific humpback dolphins (Sousa chinensis) reside in shallow coastal waters where they are exposed to potentially toxic elements (PTEs) through dietary intake. We quantitatively assessed the risk posed by eight PTEs to the health of S. chinensis by determining their concentration in 13 fish species. The fish species represented the primary pr...
Article
Cetaceans accumulate persistent and toxic substances such as polybrominated diphenyl ethers in their tissue. PBDEs are ubiquitous in marine environments, and their exposure to mammals is linked to numerous health effects such as endocrine disruption, neurotoxicity, carcinogenicity, and fetal toxicity. However, the toxicological effects and mechanis...
Chapter
Full-text available
Freshwater is defined as water containing dissolved salts that are below two parts per thousand (<0.2‰). In contrast, the concentration of dissolved salts in marine water is above 0.2‰. Freshwater ecosystems are an aquatic system formed in freshwater bodies through the interaction of organism communities and the physical components of their habitat...
Book
Full-text available
Chiral Organic Pollutants introduces readers to the growing challenges of chirality in synthetic chemicals. In this volume, contributors brilliantly summarize the characteristics of chiral pollutants to provide tools and techniques for effectively assessing their environmental and human health risks. Chapters cover recent research on the physicoche...
Chapter
Full-text available
Halogenated organic contaminants of emerging concern that have at least one chiral center such as brominated flame retardants, perfluorooctane sulfonate, perfluorocarboxylic acid, and chlorinated paraffins are frequently detected in the environment. Several studies have shown enantiomers of chiral compounds often have different fate and toxicities....
Chapter
Full-text available
Personal care products are bioactive compounds, and their presence in the environment is an issue of global concern. They are a diverse group of chemicals that are used to improve the quality of life. Examples of personal care products include UV filters, synthetic musk fragrances, disinfectants, food additives, biocides, preservatives, and cosmeti...
Chapter
Full-text available
More than 50% and 30% of pharmaceuticals and agrochemicals are chiral compounds that exist as two or more enantiomers. Enantiomers of a chiral compound often have different properties in biological systems. For example, enantiomers of a chiral pharmaceutical often have different therapeutic and toxicological characteristics. Several studies have sh...
Chapter
Full-text available
Chemical pollution is a major threat to environmental and human health. Some chemical pollutants such as pesticides, pharmaceuticals, polychlorinated biphenyls, halogenated flame retardants, and plasticizers are persistent, bioaccumulative, and potentially toxic. It is estimated that at least 50%, 30%, 9.1% of pharmaceuticals, pesticides, and polyc...
Chapter
Full-text available
Since more than 50% of drugs on the market are chiral, chiral synthesis plays a vital role in drug discovery and development. Enantiomers of chiral drugs sometimes have different pharmacodynamics and pharmacokinetics. Hence, there has been a trend toward switching from marketing racemates to single enantiomers. Understanding the mechanisms of chira...
Chapter
Full-text available
At least 30% and 50% of pesticides and pharmaceuticals are chiral compounds, respectively. Chiral molecules share similar physicochemical properties in an achiral environment but have considerable differences in a chiral environment. However, some chiral molecules have configurational lability, as their enantiomers can convert to the other enantiom...
Article
Pantropical spotted dolphins are apex predators and have a long lifespan, which makes them susceptible to chemical pollutants such as polybrominated diphenyl ethers (PBDEs), which are associated with immunotoxicity in wildlife. However, the effects of PBDEs and their mechanism of immunotoxicity in dolphins is largely unknown. Previously, we establi...
Article
AuthorAID, LinkedIn and WeChat can help to plug the connections gap when events get cancelled, says Edmond Sanganyado.
Article
Full-text available
Microplastics have a strong affinity for potentially toxic organic pollutants such as polycyclic aromatic hydrocarbons (PAHs) and organochlorine pesticides (OCPs). Since 2005, the International Pellet Watch used plastic pellets to monitor hydrophobic organic contaminants in marine environments. We examined the spatial distribution and sources of 16...
Article
Biochar is extensively used in the remediation of pollutants because of its diverse physicochemical properties. Biochar application can alter the activity of microbial communities involved in bioremediation. However, the electrochemical behavior of biochar and its potential effect on microbial nitrate reduction remains unknown. Electron transfer be...
Article
Full-text available
Nearshore ecosystems are transitional zones which may harbor a diverse microbial community capable of degrading azo dyes under extreme environmental conditions. In this study, thirteen bacterial strains capable of degrading eight azo dyes were isolated in nearshore environments and characterized using high throughput 16S rRNA sequencing. The result...
Article
Full-text available
Estuaries and coastal environments are often regarded as a critical resource for the bioremediation of organic pollutants such as azo dyes due to their high abundance and diversity of extremophiles. Bioremediation through the activities of azoreductase, laccase, and other associated enzymes plays a critical role in the removal of azo dyes in built...
Article
Full-text available
To mark the 30th anniversary of the Americans with Disabilities Act, we asked young scientists this question: What one thing would you change about the training or careers in your field to improve accessibility for people with visible and/or invisible disabilities? A selection of their responses is below. Follow NextGen Voices on Twitter with hasht...
Article
Heavy metals may affect anaerobic fermentation processes, which could result in variations in anaerobic fermentation parameters. In the present study, the impact of changing hexavalent chromium (Cr6+) concentrations on different anaerobic fermentation parameters was investigated. The results showed that adding Cr6+ affected fermentation efficiency...
Article
Full-text available
Due to lack of training in scientific writing and sometimes unethical practices, abstracts are often poorly written, lack critical information, and sometimes contain spin. An effective abstract provides brief but adequate information on the purpose, procedure, results and implications of a study. This paper discusses the key components of a good ab...
Article
Full-text available
The quantity and complexity of scientific and technological information provided to policymakers have been on the rise for decades. Yet little is known about how to provide science advice to legislatures, even though scientific information is widely acknowledged as valuable for decision-making in many policy domains. We asked academics, science adv...
Article
Azo dyes are widely used in the textile industry despite being poorly biodegradable and highly toxic. Hence, azo dyes need to be removed from effluent prior to environmental discharge. Microbial communities are efficient for the degradation and mineralization of azo dyes. However, little is known about the functional microbial communities responsib...
Article
Full-text available
Biochar produced from straw has been shown to improve soil physicochemical properties. This review introduces the fundamental concepts, the broad applications, and underlying theory of straw biochar returning. Current developments in biochar industry and the production practices prevalent among enterprises in China are critiques. This review analyz...
Article
Nearshore environments are a critical transitional zone that connects the marine and terrestrial/freshwater ecosystems. The release of anthropogenic chemicals into nearshore ecosystems pose a human and environmental health risk. We investigated the microbial diversity, abundance and function in metal-contaminated sediments collected from the Rongji...
Chapter
Full-text available
In the past decades, biotechnologies for reutilizing the biomass harvested from the metal contaminated land draw attention to many scientists. Among those technologies, anaerobic fermentation is proven as an efficient conversion process for biowaste reduction with simultaneous recovery of biogas as an energy source. During the process of anaerobic...
Article
Full-text available
The scientific enterprise benefits from diverse perspectives. We asked young scientists to Describe your unique identity and how it contributes to your scientific work and community. Respondents from across the world shared their unique backgrounds and how those experiences shaped them. These scientists described their drive to help their communiti...
Article
Full-text available
The scientific enterprise benefits from diverse perspectives. We asked young scientists to Describe your unique identity and how it contributes to your scientific work and community. Respondents from across the world shared their unique backgrounds and how those experiences shaped them. These scientists described their drive to help their communiti...
Article
The presence of chiral pharmaceuticals in the environment is an issue of great concern since pharmaceuticals are biologically active compounds. Enantiomers of chiral pharmaceuticals often behave differently in chiral environments such as biological systems; hence, their toxicities, therapeutic properties, and environmental fate may exhibit stereose...
Article
Full-text available
Recurrent cholera outbreaks in sub-Saharan Africa (SSA) has attracted a lot of research interest, raising questions about the effectiveness of current prevention and control methods. However, research on cholera and other water-borne diseases in Africa is dominated by epidemiological studies, while investigations on the environmental drivers and re...
Article
Intensive agricultural activities have caused land degradation due to soil pollution, particularly by pesticides. However, the degradation, metabolism, and toxicity of chiral pesticides by soil microorganisms is often enantioselective. This study aimed to determine the effect of chirality on the degradation of the enantiomers of ethiprole in soil a...
Article
Heavy metal contamination has been widely studied in coastal areas around the world. However, integrative studies of heavy metals pollution by monitoring and characterizing sediments, organisms, and biomarkers as well as their holistic interactions are rare. Here, we selected a developed coastal area in eastern Guangdong, China as the study field....
Article
It seems increasingly clear that our future depends on people caring more about the environment, yet as technology develops, people seem only more disconnected from nature. We asked young scientists: How can scientists in your field help people see the value of our natural environment? Scientists from across the world, with expertise in a variety o...
Chapter
Full-text available
Hiding from the blistering heat, a brawny calf with a short papyrus rope tied around its neck leaned on a mopane tree. Tears rolled down the calf’s eyes as if aware of its impending doom. A swarm of flies delivered a sad eulogy as they buzzed around the calf’s nose. An uninvited cloud of dust swirled at a distant driven by the hot and dry winds. It...
Article
In her Working Life, “Paying it forward as a mentor” (3 August, p. 522), B. Abderrahman describes how a mentor's encouragement can help shape a career. She then explains how her positive mentorship experience inspired her to mentor others. We asked young scientists to describe one quality of a mentor you've had that you will try to emulate when you...
Article
The presence of polybrominated diphenyl ethers (PBDEs) in the aquatic environment is an issue of major concern which may be a cause of increasing prevalence and severity of diseases in marine mammals. Although, cell culture model development and in vitro investigation approach is a prime need of time to progress immunotoxic research on aquatic mamm...
Article
Sugarcane and bioethanol production produces large amounts of bagasse fly ash and vinasse, which are solid and viscous liquid wastes, respectively. However, these wastes are often disposed into the environment without treatment, thus posing an environmental and public health risk. This study investigated the treatment of vinasse effluent in terms o...
Conference Paper
Abstract: In the past two decades, research interest on the role of aquaculture in deterioration of water quality in marine ecosystems has increased significantly. In 2015, China contributed to 60.5 % of the global aquaculture production due to a high demand for edible proteins that are sustainable and a vast expanse of freshwater and marine water...
Article
Research interest on chiral pesticides has increased probably because enantiomers often exhibit different environmental fate and toxicity. An investigation into the enantiomer-specific bioactivity of chiral triticonazole enantiomers in agricultural systems revealed intriguing experimental and theoretical evidence. Fungicidal activity data showed (R...
Article
Full-text available
We asked young scientists this question: How do broad interests benefit your science? Scientists with a variety of hobbies responded that their extracurricular activities have enhanced a wide range of skills, from creativity to communication to resilience. Many also mentioned the value of clearing their minds and relaxing. Follow NextGen and share...
Article
Indo-Pacific humpback dolphin (Sousa chinensis) are chronically exposed to organic pollutants since they inhabit shallow coastal waters that are often impacted by anthropogenic activities. The aim of this review was to evaluate existing knowledge on the occurrence of organic pollutants in Indo-Pacific humpback dolphins, identify knowledge gaps, and...
Article
Full-text available
Recent studies show that high-technology rare earth elements (REEs) of anthropogenic origin occur in the environment including in aquatic systems, suggesting REEs are contaminants of emerging concern. However, compared to organic contaminants, there is a lack of comprehensive reviews on the anthropogenic sources, environmental behaviour, and public...
Article
Full-text available
The 'publish or perish culture' often lead to unethical practices and mental health problems. Sadly, the problem is worse for early career researchers who often need several publications in top tier journals, graduating from reputable university and/or working under a famous supervisor to improve their chances of getting a tenure track position. Th...