Edda Cava

Edda Cava
Azienda Ospedaliero Universitaria Maggiore della Carità · Department of Dietetics and Clinical Nutrition

MD, specialist in Clinical Nutrition

About

29
Publications
9,107
Reads
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1,319
Citations
Citations since 2017
17 Research Items
1162 Citations
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2017201820192020202120222023050100150200
2017201820192020202120222023050100150200
2017201820192020202120222023050100150200
Additional affiliations
September 2004 - May 2015
Sapienza University of Rome
Position
  • Fellow

Publications

Publications (29)
Article
Full-text available
Background: Reducing obesity and weight gain, which often occurs during breast cancer treatment, may represent an efficient secondary or tertiary prevention against cancer. Purpose: This retrospective observational cohort study aimed to assess the impact of a Mediterranean diet on weight and anthropometric changes in women completing active brea...
Article
Full-text available
Regular endurance exercise training is an effective intervention for the maintenance of metabolic health and the prevention of many age-associated chronic diseases. Several metabolic and inflammatory factors are involved in the health-promoting effects of exercise training, but regulatory mechanisms remain poorly understood. Cellular senescence-a s...
Preprint
Full-text available
Regular endurance exercise training is an effective intervention for the maintenance of metabolic health and the prevention of many age-associated chronic diseases. Several metabolic and inflammatory factors are involved in the health-promoting effects of exercise training, but regulatory mechanisms remain poorly understood. Cellular senescence—a c...
Article
Full-text available
Breast cancer (BC) represents the most common cancer in women, while overweight and obesity are the second preventable cause of cancer. Weight gain and fat accumulation are common after BC diagnosis; moreover, weight gain during the treatment decreases the survival rate and increases the risk of recurrence in breast cancer survivors (BCS). To reduc...
Article
Objective Overweight or obesity are the second preventable cause of cancer, being related to 20%of diagnosis, moreover about 33%of postmenopausal breast cancers could be prevented by lifestyle modification(1). Excessive white adipose tissue (WAT) promotes a pro-oxidative microenvironment with low-grade systemic inflammation, contributing to insulin...
Article
Objective Bariatric surgery is currently considered the most effective longterm treatment to obtain substantial and sustained Weight Loss (WL) in severe and/or morbid obesity. We present data collected by a multi-disciplinary team between July 2016 and September 2020 at “Maggiore Della Carità” University Hospital (Novara, Piedmont) concerning baria...
Article
Full-text available
The high prevalence of obesity and obesity-related comorbidities has reached pandemic proportions, particularly in Western countries. Obesity increases the risk to develop several chronic noncommunicable disease, ultimately contributing to reduced survival. Recently, obesity has been recognized as major risk factor for coronavirus disease-19 (COVID...
Article
Purpose of review: This manuscript reviews evidence collected during COVID-19 pandemic and provides information on the impact of body composition on severity and outcomes of the disease, analysing methods used for body composition assessment. Malnutrition-screening tools will also be discussed to screen and diagnose the patients at higher risk of...
Article
In adults, a very uncommon presentation of celiac disease (CD) is a “Celiac Crisis”: a life-threatening and severe form of the disease having a dramatic onset with diarrhea, metabolic acidosis with electrolyte and fluid imbalance. Celiac crisis treatment requires a gluten free diet, but the risk of “Refeeding syndrome” (RFS) should be considered in...
Article
Bariatric surgery is currently considered the most effective treatment to obtain a substantial weight loss sustained on the long term in morbid obesity. We present data regarding the recent bariatric experience of candidates enrolled between July 2016 and 2018 at “Maggiore Della Carità” Novara hospital. According to international and national guide...
Article
Full-text available
The aim of the current study was to study the efficacy and safety of REMD-477, a glucagon receptor antagonist, in type 1 diabetes. This was a randomized controlled trial in which 21 patients with type 1 diabetes were enrolled. Glycemic control and insulin use were evaluated during outpatient and inpatient settings, before and after, a single 70-mg...
Data
Fig. S1 Protein Restriction and Prostate Cancer Study Flow Diagram. Table S1 Body composition, plasma lipids and PSA levels at baseline and after 1 month of dietary intervention.
Data
Appenix S1. Subjects, experimental procedures and methods.
Article
Full-text available
Obesity, metabolic syndrome, and hyperleptinemia are associated with aging and age-associated diseases including prostate cancer. One experimental approach to inhibit tumor growth is to reduce dietary protein intake and hence levels of circulating amino acids. Dietary protein restriction (PR) increases insulin sensitivity and suppresses prostate ca...
Article
Full-text available
Weight loss is the cornerstone of therapy for people with obesity because it can ameliorate or completely resolve the metabolic risk factors for diabetes, coronary artery disease, and obesity-associated cancers. The potential health benefits of diet-induced weight loss are thought to be compromised by the weight-loss-associated loss of lean body ma...
Article
Full-text available
Protein-restricted (PR), high-carbohydrate diets improve metabolic health in rodents, yet the precise dietary components that are responsible for these effects have not been identified. Furthermore, the applicability of these studies to humans is unclear. Here, we demonstrate in a randomized controlled trial that a moderate PR diet also improves ma...
Article
Background & aims: Extra virgin olive oil (EVOO) improves post-prandial glycaemia in healthy subjects but it has never been investigated if this can be detected in pre-diabetic patients. We investigated if EVOO affects post-prandial glucose and lipid profile in patients with impaired fasting glucose (IFG). Methods: Thirty IFG patients were rando...
Article
Full-text available
Calorie restriction (CR) retards aging, acts as a hormetic intervention, and increases serum corticosterone and HSP70 expression in rodents. However, less is known regarding the effects of CR on these factors in humans. Serum cortisol and molecular chaperones and autophagic proteins were measured in the skeletal muscle of subjects on CR diets for 3...
Article
The dietary treatment for weight loss in overweight and obesity has been approached in many different dietary models. Nevertheless, besides the size of weight loss, the main outcomes should be mostly the improvement of body composition (loss of body fat and preservation of lean body mass), long-term maintenance, nutritional quality of the diet, low...
Article
Full-text available
Reduced dietary protein intake and intermittent fasting (IF) are both linked to healthy longevity in rodents, and are effective in inhibiting cancer growth. The molecular mechanisms underlying the beneficial effects of chronic protein restriction (PR) and IF are unclear, but may be mediated in part by a down-regulation of the IGF/mTOR pathway. In t...
Article
Full-text available
Calorie Restriction (CR) without malnutrition slows aging and increases average and maximal lifespan in simple model organisms and rodents. In rhesus monkeys long-term CR reduces the incidence of type 2 diabetes, cardiovascular disease and cancer, and protects against age-associated sarcopenia and neurodegeneration. However, so far CR significantly...
Article
Full-text available
Unlabelled: Malnutrition occurs frequently in the elderly with important clinical and functional consequences. Moreover, the treatment of malnutrition in the elderly may be effective if clinical and nutritional interventions are performed in the early stages. Therefore the early identification of the risk of malnutrition using validated and handy...
Article
Full-text available
Objective: A combination of bioactive food ingredients (capsaicinoids, epigallocatechin gallate, piperin, and l-carnitine, CBFI) may promote satiety and thermogenesis. The study was conducted in order to assess whether there is any effect on satiety, resting energy expenditure (REE), respiratory quotient, glucagon-like peptide-1 (GLP-1), free fatt...
Article
Full-text available
Malnutrition occurs frequently in the frailest groups of the population, especially in people who are on a low income and elderly subjects, overall if they are institutionalized. The aim of this study was to assess the prevalence of malnutrition in a sample of elderly people living in different settings and to identify the determinants of malnutrit...
Article
Full-text available
The coordinative pattern is an important feature of locomotion that has been studied in a number of pathologies. It has been observed that adaptive changes in coordination patterns are due to both external and internal constraints. Obesity is characterized by the presence of excess mass at pelvis and lower-limb areas, causing mechanical constraints...
Article
Full-text available
This randomized, double blind, placebo-controlled, 8 week trial assessed the efficacy on metabolic changes produced by a consumption of a combination of bioactive food ingredients (epigallocatechin gallate, capsaicins, piperine and L-carnitine) versus a placebo, as part of a therapeutic 'lifestyle change' diet, in 86 overweight subjects. Forty-one...

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