Ebubekir Ceylan

• Doctor of Veterinary Medicine
• Professor (Full) at Ankara University

The aim of this study was to determine dynamic thiol-disulphide homeostasis (TDH) parameters and ischemia modified albumin (IMA) levels in calves with neonatal diarrhea and compare with healthy controls. A total of 50 calves were included in the study. There were 25 calves in both diarrhea and healthy groups. Serum native thiol, total thiol, disulf...

Ruminant plasentaları sindesmokoryal tipte olduğu için maternal sirkülasyonla yavru sirkülasyonubirbirinden ayrılmaktadır. Bu sebeple yenidoğan buzağılar neonatal dönem olarak da isimlendirilendoğumu takiben ilk 28 günlük periyotta, annelerinin kolostrumundan alacakları bağışıklıkbileşenlerine ihtiyaç duyarlar. Pasif immun transfer başarısı için to...

Objective Lycopene is a carotenoid with anti-inflammatory and antioxidant properties. The aim of this study was to determine the effects of lycopene on oxidative DNA damage levels in experimental diabetic rats. Subjects and Methods Four experimental groups, each consisting of 7 rats, were prepared as Controls, Diabetes (D), Lycopene-treated diabet...

In this study, umbilical cord-derived neonatal tetanus in calves was identified in Turkey. Four calves with tetanus-specific history and clinical findings were used. Blood samples were taken before and after treatment, and clinical findings were recorded. A tetanus-specific treatment procedure was performed. However, the calves died from not respon...

ABSTRACT Foot and-mouth disease (FMD) is an acute, highly contagious inflammatory viral disease of domestic and wild animals which causes decrease in productivity and lead to mortality. This study was conducted to investigate the levels of copper, zinc, magnesium and iron, -tocopherol, vitamin D3 , vitamin C and lipid peroxidation in cow with foot...

Theileriosis encountered frequently in Van region and causes huge economic losses in cattle, sheep and goats. This study was carried out to examine the serum biochemical profile and serum protein fractions, determined before and 7 days after buparvaquone treatment, in 28 cattle, diagnosed to be infected with T. annulata and in 15 healthy control an...

This study was conducted with the purpose of researching the effect of lycopene application on lipoprotein, paraoxonase (PON) and cytokines that are projected to be used in the diagnosis and treatment of diabetes by making experimental diabetes. At the end of a 1-month trial period, under ether anesthesia with jelly tubes, blood samples were taken...

This study was planned to determine the effects of lycopene treatment on serum protein fractions in experimental diabetic rats. In order to induce diabetes in rats in the diabetes (D) and diabetes + lycopene (DL) groups, rats were given 45 mg/kg single-dose streptozotocin intraperitoneally. Lycopene (10 mg/kg/day dissolved in sunflower oil) was adm...

The purpose of this study was to investigate the effects of PPARα agonist on metabolic parameters in naturally Fasciola-infected sheep. Twenty sheep with fasciolosis were allotted in 2 equal groups according to the received treatment (triclabendazole/levamisole in the group I and triclabendazole/ levamisole + PPARa agonist (2-methyl-2-phenoxy-propi...

In this study, the anti-inflammatory and antioxidant known as lycopene was applied to rats with experimental diabetes with the aim of investigating the detection of diabetes-related complications, and to determine the possible role of lycopene in diabetes complications regarding the effects of ACE activity. In order to induce diabetes in rats in th...

The aim of this study was to investigate the therapeutic effect of doramectin applied once in an optimum dose on stomach-intestine nematodes on goats naturally infected with gastrointestinal nematodes. Alto to study the effect of the doramectin application on the clinically important biochemical parameters, electrolytes, minerals, vitamin B(12) lev...

The purpose of this study is to examine changes in some biochemical parameters of treatment with tulathromycin in Montofon calves with pneumonia. For this purpose, 30 claves exhibiting clinical sings of pneumonia with fever, cough, lack of appetite, nasal flaring, mandibular lymph node enlargement dyspnea and nasal discharge were studied. A control...

The purpose of this study was to investigate examine changes in venous blood gases of Brown Swiss calves with pneumonia. For this purpose, 30 calves exhibiting having clinical sings of pneumonia and 20 healthy calves were used. Venous blood samples were collected from the healthy and diseased calves before and after treatment with Draxxin (tulathro...

This study was conducted to search how some biochemical parameters were affected just before and after birth in Siirt hairgoats. Blood samples were collected from V.jugularis almost at the last week of pregnancy and the 7 lh. day after birth. Glucose, urea, BUN, total protein, albrimin, cholesterol and trigliserit concentrations in blood samples an...

The purpose of this study, was to investigate the effects of Onion Juice Administration (OJA) on Electrocardiogram (ECG) in dogs. Five clinically healthy street dogs were used in this study. Onion juice was given through oro-gastric tube of 400 g onion kg-1 body weight dose in 500 mL water. Blood samples were collected at just before and after (6,...

The aim of this study, was to evaluate the changes of electrolytes (Na, K), minerals (Ca, Mg, P, Fe) and some parameters related to mineral metabolism (iron binding capacity, Transferrin, Ferritin, Folate, Vitamin B12), just before and after parturition, in healthy Siirt hair goats. For this aim, 10, healthy, 2-4 years old, female Siirt hair goats,...

The aim of this study was to examine the efficacy of rnoxidectin treatment on goats naturally infected with gastrointestinal nematodes in Van region, Turkey. Two hundred and forty goats infected with gasterointestinal parasites were treated with 0.2 rug kg-1 moxidectin (Cydectin, Abfar), subcutaneously. Ten randomly selected goats were not treated...

The present study was earned out to determine the seroprevalence of antibodies to C. burnetii in cattle and sheep in the east of Turkey. Sennn samples collected randomly from 92 cattle and 92 sheep were examined by ELISA (Vircell-SL, Spain) to detect IgG antibodies against C. burnetii phase II antigen. Seropositivity was observed in 16.3% of the ca...

Abstract: The aim of this study was to investigate the changes in the blood serum concentration of some biochemical parameters and lipid-soluble vitamin levels in the goats naturaly infested with lice and Trichostrongylidae sp. before and after treatment with moxidectin and effects of moxidectin treatment on these blood parameters. In this study, 2...

The aim of the study was to investigate the effect of carrying heavy load for a long time on lipid peroxidation (MDA: malondialdehyde), NO2 (nitrite), NO3 (nitrate), antioxidants (GSH: reduced glutathione, retinol, alpha-tocopherol) and vitamin D-3 in healthy horses. Blood samples from seventeen native 3-5 years age and 450-500 kg live weight Anato...

To present the results of a cross-sectional epidemiological analysis of a familial outbreak of fascioliasis in Eastern Anatolia and to discuss the clinical, diagnostic and therapeutic properties of the patients. A screening group consisting of 92 individuals from the same family with a history of watercress ingestion and a control group consisting...

The present study was carried out to assess the prevalence of motile Aeromonas spp. in the faeces of clinically healthy sheep, cattle and horses and evaluate their susceptibility to some anti-microbial agents. Rectal swabs from 120 sheep, 85 cattle and 20 horses were examined for Aeromonas species using alkaline peptone water (pH 8.4) as the enrich...

This study was carried out to investigate whether streptozotocin induced diabetic rats could effect some of serum biochemical parameters. Twenty Sprague-Dawley albino rats were divided into two experimental: Control (50 mg/kg SF) and streptozocin (60 mg/kg), Control rats were given only physiological saline (50 mg/kg). Serum glucose, AST, ALT and c...

Eight private farms as groups were used in the study. Each group contained randomly selected ten goats. These animals were fed forage and concentrated feed, Serum glucose, total protein, albumin, globulin, cholesterol, and triglyceride levels, and ALP (alkaline phosphatase), ALT (alanine -amino transferase), AST (aspartate amino transferase), GOT (...

In the present study the role of Zn, Cu and thyroid hormone concentrations in the heifers having retardation of the growth problem were aimed to investigate. In this study, 11 Eastern Anatolian Red heifers weighing 35-50 kg body weight (test group) and 6 Eastern Anatolian Red heifers in normal body weight (80-100 kg) (control group) aged between 6-...

Brucellosis Seropositivity in Human and Animal Population in Some Villages of Van Province Abstract: Aim: To evaluate of the prevalence of brucellos is among sheep, goats, cattle and their owners in villages of Van. Method: Blood samples were taken from 558 humans, 336 sheep, 51 goats and 129 cattle from 5 villages in the region of Van between...

In this study, fixed oil of P. anisum was investigated for anti-inflammatory activity using carrageenan-induced rat paw oedema test on the Sprague-Dawley rats and analgesic activity using tail-flick test on the Swiss-albino mice. Indomethacin and etodolac were treated reference drugs for the anti-inflammatory activity. Aspirin and morphine hydrochl...

Cryptosporidium is a minute coccidian protozoon belonging to phylum Apicomplexa. Twenty species of this parasite have been described from a variety of vertebrates including mammals, birds, reptiles and fish. Development of the Cryptosporidium occurs within the brush border. of the epithelial cells of the intestine. Sporulated oocysts, containing fo...

Cryptosporidium infection is a zoonotic disease caused by Cryptosporidium spp. and transmitted by faecal-oral cycle. Young animals are most likely to develop symptomatic infections and shed high quantities of infective oocysts. But infection in adult animals is asymptomatic and number of oocysts shed is usually very fewer than from young animals. (...

Equine infectious anemia (EIA), colloquially known as swamp fever, mountain fever, slow fever, equine malarial fever and Coggins disease, is a viral disease infecting all members of the Equidae including, horses, ponies, mules, and donkeys. (Sellon, 1993; Nakajima and Sugiura, 1994; Burki et al., 1992). Transmission of the virus requires direct blo...

The study revealed that laminitis caused a significant (P<0.01) decrease of 15-20% milk yield in sheep. In the treated group the decrease was seen upto 5" week, whereas in the untreated group it persisted upto the end of the observation period. This decrease in milk yield might be due to insufficient intake of feed because of painfull lesions in th...

A decoction extract of Rheum ribes roots was given orally and tested for hypoglycemic effect in healthy and in alloxan-diabetic mice. The results were compared with glibenclamide, a standard hypoglycemic agent, and control groups. It was found that the extract possesses a hypoglycemic effect in diabetic animals.

Objective: To determine lethal doses of fixed and/or volatile oils extracted from leafs or fruits of Pimpinella anisum, Foeniculum vulgare, Sesamum indicum, Eugenia caryophyllata, Nigella sativa, Urtica pilulifera, Apium graveolens, Cuminum cyminum, Coriandrum sativum and Thymus fallax, Method: Swiss albino mice were injected intraperitoneally with...

The present study was carried out to assess the prevalence of motile Aeromonas sp. in the faeces of healthy dogs and to evaluate its susceptibility to some anti-microbial agents. Rectal swabs from 55 domestic dogs were examined for Aeromonas species using alkaline peptone water (pH 8.4) as the enrichment medium and Aeromonas Selective Agar containi...

The onset time was shorter but the time of action was longer using mivacurium at the dose of 0.4 mg/kg than the atracurium at the dose of 0.6 mg/kg. Atracurium could be used for intubation but when long time of myorelaxation was needed, both atracurium and mivacurium could be used safely.

Blood parameters and rumen contents of 9 Akkaraman yearling lambs which accidentally have taken too much grain and six healthy yearling lambs (control) were investigated for acidosis. Blood pH and blood bicarbonate levels were lower (P<0.001), Blood lactic acid was elevated. Hematocrit, Haemoglobin, blood urea and blood gulcose levels were also ele...

Feeding lambs with high grain rations (80-95% concentrate) generally increases the incidence of digestive disturbances related with rumen acidosis (Britton and Stock, 1986). Rumen acidosis varies from subacute to acute from, and is associated with various secondary disordes such as laminitis, polioencephalomalacia, rumenitis, and liver abscesses (B...

Leptospirosis is a systemic infection usually producing fever with hepatorenal involvement, meningoencephalitis, and hemorrhage. In this article, we present three children between 10 and 13 years of age with leptospirosis. The purpose of this paper is to emphasize that leptospirosis is a problem in our country with farmers/cattle and that leptospir...

The role of Nigella sativa L. (Ranunculaceae) (NS) and Urtica dioica L. was investigated (UD) in the prevention of carbon tetrachloride (CCl4) induced liver fibrosis and cirrhosis. Fifty Sprague-Dawley rats were allocated into fi ve groups (I, IIA and B, IIIA and B) and CCl4 was injected biweekly to all groups. Group I (control, CCl4 only), group I...

To compare the effects of atracurium and mivacurium as muscle relaxants, 40 dogs were treated with different doses of these drugs. The onset time of action was shorter but the time of action was longer in mivacurium group then the atracurium groups. Therefore, it was concluded that on occasions when immediate intubation and long term muscle relaxat...

Investigation of The Level of The Median Lethal Dose (LD 50 ) and The Hypoglycemic Effect of Cuminum cyminum L. Fruit Essential Oil Extract in Healthy and Diabetic Mice Aim: Investigation of the level of the median lethal dose (LD50) and the hypoglycemic effect of Cuminum cyminum L. fruit essential oil extract in healthy and diabetic mice. Method:...

The aim of this study was to investigate the effect of different doses of prednisolone in puppies experimentally induced with meconium aspiration syndrome (MAS). Meconium was collected from human babies in the first day of life and was released into the trachea of 11 newborn puppies to induce MAS. Puppies were treated with 2 mg/kg prednisolone (sta...

Pseudopericarditis has been used to describe jugular engorgement and oedema of the brisket and ventral abdominal wall. Similar symptoms can be seen in cattle with traumatic pericarditis. Pressure caused by tumours, abscesses, Echinococcus cysts, swollen lymph nodes resulting from tuberculosis and leukosis, one-sided pleuritis and diaphragmatic hern...

The level of vitamin E, vitamin C, B-Carotene and retinol, Zn and Cu, pH, pCO2, HCO3, oxygen saturation, PCV and Hb values, glucose, lactate, Na, K and Cl were measured in rams with subclinic acidosis characterized laminitis. Glucose and lactate levels, Cu concentration and PCO2, and HCO3 values were found significantly higher but PO2, and HCO3 val...

In vivo (n = 16) and in vitro (n = 16) experiments were conducted in dogs to describe the effects of sildenafil citrate (viagra) on histopathological changes during the healing process with respect to angiogenesis and compare vasodilatative effects of sildenafil citrate, acetylcholine and sodium nitroprusside. General anaesthesia was performed with...

Ceylan, E., Akkan, H. A., Tutuncu, M., Z. Agaoglu: Nephrotoxic Effect of Amphotericin B Administered in Different Doses and Infusion Mode in Dogs. Acta Vet. Brno 2003, 72: 229-234. In this study, nephrotoxic effect of Amphotericin B (AmB) was investigated together with clinical, biochemical, and histopathological findings in dogs intoxicated with d...