Ebele AjagunAhmadu Bello University | ABU · Department of Pharmacology and Therapeutics
Ebele Ajagun
B.Pharm, FcPharm, M.Sc (Pharmacology)
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13
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Publications (13)
This chapter discusses natural compounds recognized for their antiaging properties and describes the underlying mechanisms of action, providing a concise synopsis of studies on the efficacy of herbal extracts in antiaging products. The potential of certain herbal extracts, such as green tea, ginkgo, licorice, Aloe vera, and ginseng, in treating var...
Parkinson’s disease (PD), also known as Parkinsonism, is a neurological condition that mostly, but not solely, impairs movement control. It is distinguished by an increased deterioration and loss of dopamine-producing neurons in the substantia nigra area of the brain. The exact aetiology of PD is complicated and multifaceted. It is considered to co...
Parkinson’s disease (PD) or Parkinsonism is an age-related progressive neurological disorder because of the deterioration of the nerve cells inside the substantia nigra, and it is characterized by three cardinal signs: rigidity, resting tremor, and bradykinesia. The major aim of therapy is to control the disorder’s signs and symptoms, delay the pro...
Chemotherapy-associated side effects significantly contribute to the challenges of cancer treatment, impacting the well-being of patients and complicating existing conditions. Chemotherapy-induced oedema, characterized by abnormal fluid accumulation and swelling, worsens cancer-related issues, such as impaired wound healing. This oedema may result...
Cannabis sativa L. is an annual herbal plant of the family Cannabinaceae and abundant in nature. It is known locally as igbo, taba, blaze, joint, pot, dope, ganja, sensi, kpoli, weed, and morocco on the streets of Nigeria, and used as a medicinal plant for many centuries in many different parts of the world. Although native to Central Asia, Cannabi...
This work investigated some physical and thermal properties of kariya (Hildegardia barteri) kernel to provide data for designing post-harvest equipment. Models were also established for all the parameters measured for as a function of moisture content, with high correlation coefficients.
Treatment and management of cancer in Nigeria and many parts of Africa has included the use of combination (recipe) of defined medicinal plants of different genera and family. There has been little research work to validate the in vitro cytotoxicity of recipes derived from the combination of these plants. Therefore, this research work was carried o...
Aim: This survey was carried out to determine the prevalence of foetal wastage amongst cattle and goat; and its associated economic loss. Study Design: A retrospective survey was carried out using the abattoir records of Owode Veterinary Hospital, Ogbomoso, were relevant data relating to foetal wastage was retrieved. Place and Duration: The study w...
Diseases in animals not only constitute health challenges in man but are also a major source of economic losses. Hence, the proper identification, understanding, management and documentation of diseases prevalent in animal husbandry would go a long way in controlling the dissemination of zoonotic diseases and reduce the financial implication on the...
Aims: To investigate the phytochemical composition and effect of temperature on the proximate and mineral composition of Zingiber officinale.
Study Design: Activity directed phytochemical screening, proximate analysis and mineral composition investigation of Z. officinale rhizomes using in vitro methods. Place and Duration of Study: Medicinal Plan...
The rising cost as well as the negative associated adverse effects of orthodox medicines has ultimately resulted in wide acceptance of traditional based medications. The study reports the uses of animal species and parts practised by the people of Ogbomoso, Oyo State. An ethno-zoological survey of the Ogbomoso people of Oyo state (Nigeria) was cond...
Questions
Questions (8)
Good evening Sir/Ma,
Please I need the name of a herb-drug interaction software for some work. Can anyone suggest a good one. Thank you
When looking at the toxic effect of an extract on organs should I use relative organ weight or absolute organ weight. Thank you
Good evening Ma/Sir, trust you all are in good health. I am interested in learning docking using Autodock and UCSF chimera. Please where can I get materials (videos) that can guide me especially in the area of active/binding site determination. Thank you.
Kind Regards
What are the basic analysis to be conducted after administration of the test dose of plant extract ( aside haematological effect and effect on liver enzymes). Thank you
Preferably both invitro and invivo antidiabetic mechanism of action for an unknown plant extract
I am trying to validate the efficacy of ethanolic extracts on common sexually transmitted infections in man.
Prospective and retrospective study designs
I want to test the efficacy of a plant extract as an anti-tumor agent.