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Introduction
Skills and Expertise
Publications
Publications (27)
Containing the COVID-19 pandemic requires rapidly identifying infected individuals. Subtle changes in physiological parameters (such as heart rate, respiratory rate, and skin temperature), discernible by wearable devices, could act as early digital biomarkers of infections. Our primary objective was to assess the performance of statistical and algo...
Prior research has demonstrated how immune functioning and physiological signals fluctuate across the menstrual cycle, with eumenorrheic women more likely to become ill during the luteal phase. Examining such changes during the current pandemic, we explored how the relationship between menstrual cycle phase and physiological signals impacts a weara...
Bayesian statistics is an approach to data analysis based on Bayes’ theorem, where available knowledge about parameters in a statistical model is updated with the information in observed data. The background knowledge is expressed as a prior distribution and combined with observational data in the form of a likelihood function to determine the post...
A Correction to this paper has been published: https://doi.org/10.1038/s43586-021-00017-2.
Objectives
It is currently thought that most—but not all—individuals infected with SARS-CoV-2 develop symptoms, but that the infectious period starts on average two days before the first overt symptoms appear. It is estimated that pre- and asymptomatic individuals are responsible for more than half of all transmissions. By detecting infected indivi...
The popularity and use of Bayesian methods have increased across many research domains. The current article demonstrates how some less familiar Bayesian methods can be used. Specifically, we applied expert elicitation, testing for prior-data conflicts, the Bayesian Truth Serum, and testing for replication effects via Bayes Factors in a series of fo...
Objectives
It is currently thought that most—but not all—individuals infected with SARS-CoV-2 develop symptoms, but the infectious period starts on average 2 days before the first overt symptoms appear. It is estimated that pre- and asymptomatic individuals are responsible for more than half of all transmissions. By detecting infected individuals b...
Rationale
Ischemia and subsequent reperfusion cause myocardial injury in patients presenting with ST-segment elevation myocardial infarction (STEMI). Hydrogen sulfide (H2S) reduces “ischemia-reperfusion injury” in various experimental animal models, but has not been evaluated in humans. This trial will examine the efficacy and safety of the H2S-don...
Randomized response (RR) designs are used to collect response data about sensitive behaviors (e.g., criminal behavior, sexual desires). The modeling of RR data is more complex, since it requires a description of the RR process. For the class of generalized linear mixed models (GLMMs), the RR process can be represented by an adjusted link function,...
Deficiencies in discriminating and identifying speech sounds have been widely attested in individuals with dyslexia as well as in young children at family risk (FR) of dyslexia. A speech perception deficit has been hypothesized to be causally related to reading and spelling difficulties. So far, however, early speech perception of FR infants has no...
Background
Bayesian estimation with informative priors permits updating previous findings with new data, thus generating cumulative knowledge. To reduce subjectivity in the process, the present study emphasizes how to systematically weigh and specify informative priors and highlights the use of different aggregation methods using an empirical examp...
In a broad range of fields it may be desirable to reuse a supervised classification algorithm and apply it to a new data set. However, generalization of such an algorithm and thus achieving a similar classification performance is only possible when the training data used to build the algorithm is similar to new unseen data one wishes to apply it to...
Experts provide an alternative source of information to classical data collection methods such as surveys. They can provide additional insight into problems, supplement existing data, or provide insights when classical data collection is troublesome. In this paper, we explore the (dis)similarities between expert judgments and data collected by trad...
In a broad range of fields it may be desirable to reuse a supervised classification algorithm and apply it to a new data set. However, generalization of such an algorithm and thus achieving a similar classification performance is only possible when the training data used to build the algorithm is similar to new unseen data one wishes to apply it to...
Individual assessment of infants' speech discrimination is of great value for studies of language development that seek to relate early and later skills, as well as for clinical work. The present study explored the applicability of the hybrid visual fixation paradigm (Houston et al., 2007) and the associated statistical analysis approach to assess...
Background
Guidelines recommend treating patients with an internal carotid artery near occlusion (ICANO) with best medical therapy (BMT) based on weak evidence. Consequently, patients with ICANO were excluded from randomized trials. The aim of this individual‐patient data (IPD) meta‐analysis was to determine the optimal treatment approach.
Methods...
Due to a coding error the marginal likelihoods have not been correctly calculated for the empirical example and thus the Bayes Factors following from these marginal likelihoods are incorrect. The corrections required occur in Section 3.2 and in two paragraphs of the discussion in which the results are referred to. The corrections have limited conse...
Introduction: The European Society for Vascular Surgery guideline recommends to treat patients with an internal carotid artery near occlusion (ICA NO) with best medical therapy (BMT). This recommendation is based on level III, class C evidence, published in 2003. From this time onwards, ICA NO was defined as a high-risk subgroup and these patients...
Response bias (nonresponse and social desirability bias) is one of the main concerns when asking sensitive questions about behavior and attitudes. Self-reports on sensitive issues as in health research (e.g., drug and alcohol abuse), and social and behavioral sciences (e.g., attitudes against refugees, academic cheating) can be expected to be subje...
In this poster we assessed discrimination performance of 6-10-month-old infants (n = 117), on a salient Dutch vowel contrast (/a:/-/e:/), at the individual level using Bayesian statistics.
Elicitation is a commonly used tool to extract viable information from experts. The information that is held by the expert is extracted and a probabilistic representation of this knowledge is constructed. A promising avenue in psychological research is to incorporated experts’ prior knowledge in the statistical analysis. Systematic reviews on elici...
Experts’ beliefs embody a present state of knowledge. It is desirable to take this knowledge
into account when making decisions. However, ranking experts based on the merit of their beliefs is a difficult task. In this paper, we show how experts can be ranked based on their knowledge and
their level of (un)certainty. By letting experts specify thei...