Duck-chul Lee

Iowa State University | ISU · Department of Kinesiology

Background: The minimal and optimal daily step counts for health improvements remain unclear. Objectives: A meta-analysis was performed to quantify dose-response associations of objectively measured step count metrics in the general population. Methods: Electronic databases were searched from inception to October 2022. Primary outcomes include...

Increasing daily steps by an additional 3000 steps/day on 5 days/week equates to ~150 min/week of aerobic physical activity to meet the physical activity guidelines; however, its effectiveness for blood pressure control in older adults with hypertension is unknown. A 20-week, single-arm, pilot e-health lifestyle walking intervention was conducted i...

Introduction The average American diet is high in red and processed meats which increases one's risk for chronic diseases and requires more land and water to produce and yields greater greenhouse gases (GHG) compared to other protein foods. Reduction of red and processed meat intake, such as seen with the Dietary Approaches to Stop Hypertension (DA...

Objectives Restrictive spirometry pattern (RSP) suggests an impairment of lung function associated with a significantly increased risk of premature mortality. We evaluated the independent and joint associations of cardiorespiratory fitness (CRF) and body mass index with incident RSP. Methods Data from the Aerobics Centre Longitudinal Study include...

Objectives Examine the independent and joint associations of cardiorespiratory fitness (CRF) and body mass index (BMI) with the prevalence of diverticulitis in older adults. Methods 476 older adults (61% Female; 71 ± 5 years) with no history of myocardial infarction, stroke, cancer, inflammatory bowel disease, or diabetes were included in this cro...

The Physical Activity Guidelines recommend performing 150 min of moderate- to vigorous-intensity aerobic physical activity (MVPA) per week. These guidelines also recommend muscle-strengthening physical activity (MSPA) on ≥2 d·wk−1 for additional benefits including muscular fitness and bone health. The majority of the scientific evidence supporting...

Depression (DEP) is prevalent and current treatments are ineffective for many people. This pilot study's purpose was to assess the feasibility, acceptability, and plausible efficacy of an 8-week intervention employing 30 min of prescribed moderate intensity exercise (“ActiveCBT”) compared to 30 min of usual activities (“CalmCBT”) immediately prior...

Whether the COVID-19 pandemic has long-lasting effects on physical activity (PA) and sedentary behavior in the vulnerable older adult population is uncertain. A total of 387 older adults (75 ± 6 years) completed a retrospective questionnaire on time spent sitting, walking, and performing aerobic and muscle-strengthening PA before, during the first...

Introduction: Poor sleep quality is associated with high blood pressure and elevated cholesterol, and regular short sleep (<7 hours) has been found to increase the risk of cardiovascular events. The American Heart Association recommends aerobic physical activity to improve sleep, although there are limited data on the effects of other popular types...

Lean mass abnormalities are highly prevalent in patients referred for cardiac rehabilitation (CR). As such, current guidelines recommend incorporating resistance exercise (RE) into the exercise prescription of Phase II-IV CR. The effects of RE on health-related outcomes in patients with cardiovascular (CV) disease (CVD) have not been extensively in...

Background Moderate to vigorous physical activity (MVPA) is strongly associated with risk reductions of noncommunicable diseases and mortality. Cardiovascular health status may influence the benefits of MVPA. We compare the association between MVPA and incident major adverse cardiovascular events (MACE) and mortality between healthy individuals, in...

Background: To examine the independent and combined association between relative quadriceps strength and the prevalence of type 2 diabetes mellitus (T2DM) in older adults. Methods: Among 1441 Korean older adults aged ≥65 years (71 [4.7] y) recruited between 2007 and 2016, 1055 older adults with no history of myocardial infarction, stroke, or can...

Objective To investigate the association between relative grip strength and the prevalence of type 2 diabetes mellitus (T2DM) independently and in combination with body mass index (BMI) in Korean adults. Methods The cross-sectional study includes 2,811 men and women (age 40 to 92 years old) with no history of heart disease, stroke, or cancer. Rela...

Background: The association between muscular strength (MS) and prevalent gastroesophageal reflux disease (GERD) in the older adults is not well established. Methods: This study included 542 older adults with no history of myocardial infarction, stroke, or cancer. MS was measured by handgrip dynamometry. Participants were categorized into sex-spe...

Health benefits of resistance exercise (RE), particularly in lowering cardiovascular disease (CVD) risks, are less understood in comparison to aerobic exercise (AE). Motivated by big data from the Aerobics Center Longitudinal Study (ACLS), we study the direct and indirect effects of RE on CVD risks. The primary outcome in our study, total CVD event...

Background Obesity is a significant and growing public health problem in high-income countries. Little is known about the relationship between resistance exercise (RE), alone and in combination with aerobic exercise (AE), and the risk of developing obesity. The purpose of this prospective cohort study was to examine the associations between differe...

Background : The purpose of this cross-sectional study was to examine the effect of physical activity (PA) on the relationship between perceived racial discrimination and major depressive disorder (MDD) in African Americans. Methods : 645 African Americans (mean age 45 years) were interviewed on their perceived racial discrimination, PA, and past...

Introduction: Familial dementia (FD) is one of the strongest risk factors for dementia. Little is known about the independent and combined associations of having FD and following a healthy lifestyle with the risk of dementia. Hypothesis: We hypothesized that FD and a healthy lifestyle would be independently associated with the risk of dementia and...

Background: Increased resting heart rate (RHR) is a predictor of mortality. RHR is influenced by cardiorespiratory fitness (CRF). Little is known about the combined associations of RHR and CRF on cancer mortality. Methods: 50,108 men and women (mean age 43.8 years) were examined between 1974 and 2002 at the Cooper Clinic in Dallas, Texas. RHR wa...

Purpose To examine the associations of total steps/day and faster aerobic steps/day (≥60 steps/min) with the development of frailty in older adults with hypertension (HTN) using a two-phased cross-sectional and prospective approach. Methods The sample consisted of 427 older adults with HTN from the Physical Activity and Aging Study (PAAS), aged ≥6...

Evidence on the associations between lifestyle movement behaviors and obesity has been established without taking into account the time-constrained nature of categorized, time-based lifestyle behaviors. We examined the associations of sleep, sedentary behavior (SED), light-intensity physical activity (LPA), and moderate-to-vigorous PA (MVPA) with b...

Background Sarcopenia is prevalent in ever growing older adult populations. Aim The aim of this study was to quantify the association between physical activity (PA), sedentary time (SED), cardiorespiratory fitness (CRF), and strength (STR) with sarcopenia in community-dwelling older adults using a standard definition of sarcopenia. Method This cr...

This review discusses the associations of muscular strength (MusS) with cardiovascular disease (CVD), CVD-related death, and all-cause mortality, as well as CVD risk factors, such as metabolic syndrome, diabetes, obesity, and hypertension. We then briefly review the role of resistance exercise training in modulating CVD risk factors and incident CV...

Background: Sedentary behavior (SB) is associated with increased risks of detrimental health outcomes. Few studies have explored correlates of SB in physically active individuals. Furthermore, SB correlates may depend on settings of SB, such as occupation, transportation and leisure time sitting. This study aims to identify subject-, lifestyle- an...

Background: Clinical evidence suggests that muscle-strengthening exercise (using weight machines/body weight exercises) may be an important antihypertensive lifestyle therapy. However, epidemiological research on the association between muscle-strengthening exercise and hypertension is limited. We conducted the first population-level study describ...

Purpose: To evaluate the independent and combined associations of cardiorespiratory fitness (CRF) and muscular strength (MS) with arterial stiffness (AS), a strong predictor of cardiovascular disease, in older adults. Methods: This cross-sectional study included 405 older adults (mean age 72 years). CRF was assessed by time (seconds) to complete...

Objective Handgrip strength is considered a biomarker of nutritional status and strength capacity, which are both linked to heart complications. However, it is not well understood how weakness, as measured by handgrip strength, factors into common heart conditions seen in aging adults such as chronic heart failure (CHF). The purpose of this study w...

A large body of evidence demonstrates positive, graded effects of PA on cardiovascular disease (CVD) morbidity and mortality with increasing intensity compared with lower PA intensity. Running is often designated as a high-intensity PA with substantial evidence supporting its health benefits. Cross-country skiing is among the most demanding aerobic...

Background Characterizing the effects of physical activity (PA) and cardiorespiratory fitness (CRF) on mortality is challenging because the causal relationship between PA, CRF, and other cardiovascular risk factors is unclear. Methods To better understand the effects of PA and CRF on mortality, we re-analyzed data from 42,373 participants in the A...

Background: The benefits of aerobic exercise (AE) for cardiovascular disease (CVD) have been well documented. Resistance exercise (RE) has been traditionally examined for its effects on bone density, physical function, or metabolic health, yet few data exist regarding the benefits of RE, independent of and combined with AE, for CVD prevention. Thi...

Objectives: We examined the overall association as well as the dose-response relationship between leisure-time running and incident type 2 diabetes. Methods: Participants were 19,347 adults aged 18-100 years who were free of cardiovascular disease, cancer, and diabetes at baseline, and who received at least 2 extensive preventive medical examina...

Introduction: Approximately half of adults have hypertension (HTN) under the 2017 blood pressure (BP) guidelines. The guidelines recommend lifestyle factors, such as limiting alcohol consumption, to manage BP, although safe levels of alcohol consumption have not been investigated for this new population with HTN. Objective: To examine the dose-resp...

Objective: To examine the association between muscular strength and incident type 2 diabetes, independent of cardiorespiratory fitness (CRF). Patients and methods: A total of 4681 adults aged 20 to 100 years who had no type 2 diabetes at baseline were included in the current prospective cohort study. Participants underwent muscular strength test...

The role of body composition in patients with heart failure (HF)has been receiving much attention in the last few years. Particularly, reduced lean mass (LM), the best surrogate for skeletal muscle mass, is independently associated with abnormal cardiorespiratory fitness (CRF)and muscle strength, ultimately leading to reduced quality of life and wo...

Although exercise has well-documented health benefits on cardiovascular disease (CVD), the benefit of combination exercise on CVD risk factors in individuals with elevated risk has not been fully elucidated. We compared the effects of aerobic, resistance, and a combination of both aerobic and resistance training on CVD risk factors including periph...

Institutional Review Board approved protocol. (PDF)

Changes in body composition are related to mobility, fall risk, and mortality, especially in older adults. Various devices and methods exist to measure body composition, but bioelectrical impedance analysis (BIA) has several advantages. The purpose of this study was to validate a common BIA device with a dual-energy X-ray absorptiometer (DXA) in ol...

Introduction Although muscle-strengthening exercise has multiple independent health benefits, little is known about muscle-strengthening exercise participation and associations with adverse health conditions among U.S. adults. Methods In 2017, data were analyzed from the U.S. 2015 Behavioral Risk Factor Surveillance System. During telephone survey...

Purpose: Resistance exercise (RE) can improve many cardiovascular disease (CVD) risk factors, but specific data on the effects on CVD events and mortality are lacking. We investigated the associations of RE with CVD and all-cause mortality, and further examined the mediation effect of body mass index between RE and CVD outcomes. Methods: We incl...

Background: Sedentary behaviour (SB) may contribute to the development of several chronic diseases, such as hypertension, diabetes mellitus (DM) and all-cause mortality. The aim of this study is to investigate the association between different domains of SB with diabetes among adult users of the Brazilian National Health System (NHS). Methods: C...

https://www.jneb.org/article/S1499-4046(18)30428-7/abstract

Purpose: To examine the associations of physical activity and cardiorespiratory fitness (hereafter fitness) with incident glaucoma in a prospective observational study. Methods: Physical activity was measured by self-reported leisure-time activities and fitness was measured by maximal treadmill test. Incident glaucoma was defined based on physic...

Purpose of review: The aim of this review is to evaluate the most recent literature about the role of physical activity, exercise, and fitness in hypertension prevention. Recent findings: Strong evidence indicates that performing moderate-to-vigorous physical activity, particularly aerobic exercise, and improving cardiorespiratory fitness (CRF)...

Physical activity and exercise are positive health behaviors that have been shown to reduce the risk of physical and psychological diseases. There is a strong rationale that physical activity could be a protective factor against the development of substance use disorders (SUDs), which include some of the most common mental health conditions such as...

There is an increasing body of evidence supporting that both fitness and fatness levels relate to current and future individuals’ health status. In this article, we discuss the meaning of fitness and fatness&sol;obesity, and make an overview of what is currently known about fitness and fatness as potentially modifiable risk factors related to healt...

Introduction: There is little evidence on the effects of muscular strength, independent of cardiorespiratory fitness, on the development of type 2 diabetes. Hypothesis: We hypothesised that muscular strength, independent of cardiorespiratory fitness, has significant benefits in type 2 diabetes prevention. Methods: Participants were 5,578 men and wo...

Introduction: Excess body fat and abdominal obesity have been associated with cardiovascular diseases. While aerobic exercise is often recommended to prevent fat accumulation, less evidence exists detailing the specific effects of resistance exercise, independent of or combined with aerobic exercise, on the development of excess body fat and abdomi...

Objective: To examine the associations of resistance exercise, independent of and combined with aerobic exercise, with the risk of development of hypercholesterolemia in men. Patients and methods: This study used data from the Aerobics Center Longitudinal Study, which is a cohort examining the associations of clinical and lifestyle factors with...