. Dr. Shaban Awidat

University of Tripoli | UOT · pharmacology and toxicology

The effects of repeated oral administration of clarithromycin (7.5 mg/Kg B.W., daily for 5 consecutive days) on blood parameters, clinico-chemical parameters and vital organ histology were evaluated in Ross broiler chickens. Twelve clinically healthy birds have been used in a parallel study design, where they have been randomly divided into two gro...

The pharmacokinetics of clarithromycin at a dose of 7.5 mg/kg body weight was evaluated after single intravenous (i.v.) and intracrop (i.c.) bolus administrations in broilers. An HPLC assay using pure clarithromycin base as a standard was used to measure its concentrations in plasma. Following an i.v. bolus injection, the plasma concentration-time...

Background: Tilmicosin is a macrolide antibiotic used mainly for controlling respiratory infections in animals. Tilmicosin therapy, like that with other macrolide members, may be associated with various adverse effects on different organ functions that remain a controversial matter. Therefore, the object of the present study was to investigate the...

The comparative blood, egg and tissue residues as well as the adverse effects of enrofloxacin represented in Enrotryl and Baytril were investigated in laying hens following repeated oral administration ® ® at a dose rate 10 mg enrofloxacin base /kg b. wt., once daily for 5 consecutive days. Enrofloxacin in both products was microbiologically assaye...

The present study aimed at evaluation of the immuomodulatory effect of sulphadimidine by investigating its ability to affect constitutive expression of MHC-II molecules on B-cells, which are one determinant of antigen presentation and the vigor of immunity. Three groups of broiler chicken were used, the first two groups received 100 mg/kg and 200 m...

The object of the present study was to assess the possible alterations in blood of sheep that may occur following intramuscular injection of tobramycin. Tobramycin was injected to 10 sheep at a dosage regimen of 5 mg/kg of body weight for 5 successive days. Two types of blood samples (with and without EDTA as an anticoagulant) were collected from t...

2 Abstract: The comparative blood, egg and tissue residues as well as the adverse effects of enrofloxaci n represented in Enrotryl and Baytril were investigated in laying hens following repeated oral administration ® ® at a dose rate 10 mg enrofloxacin base /kg b. wt., once daily for 5 consecutive days. Enrofloxacin in bot h products was microbiolo...

The comparative bio-equivalence of Dolistin and Colidox at a dose rate of 10 mg doxycycline/kg ® ® b. wt. was studied in 48 clinically normal broiler chickens. After oral administration, plasma levels of doxycyline peaked after 2 hours post-dosing without significant differences between the two products and it could be detected therapeutically and...