Dr. Satyendra K Prasad

Dr. Satyendra K Prasad
Rashtrasant Tukadoji Maharaj Nagpur University · Department of Pharmaceutical Science

M. Pharm, Ph.D.

About

72
Publications
31,269
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2,688
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Introduction
I am presently working as a Assistant Professor at Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, India. My area of research includes Pharmacognosy, Phytochemistry, Phytotherapy research, Ethnopharmacology, Organic cultivation of medicinal plants, Standardization of medicinal plants and polyherbal formulation along with analytical profiling of medicinal plants and polyherbal formulations.
Additional affiliations
July 2007 - October 2013
Indian Institute of Technology (Banaras Hindu University) Varanasi
Position
  • Researcher
Education
July 2003 - April 2006

Publications

Publications (72)
Article
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Bhallatakadi Ghrita' (BG), comprising the plant extracts of Semecarpus anacardium L., Argemone mexicana L., Cocculus hirsutus L., and Woodfordia fruticosa K. 'Murcchana samskara' of ghee before any 'ghrita-paka' preparation evidenced the maximum acceptability for topical application. The current study dealt with the effect of the 'Murcchana' proces...
Article
Background and objective: Leaves of plant Dolichandrone falcata Seem. are traditionally used by the healers of “India” for the treatment of piles and diabetes. Therefore, the main objective of the present investigation was to evaluate the anti-hemorrhoidal potential of ethanolic leaf extract from the plant D. falcata (EDF). Methods: D. falcata leaf...
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Saikosaponins are major biologically active triterpenoids, usually as glucosides, isolated from Traditional Chinese Medicines (TCM) such as Bupleurum spp., Heteromorpha spp., and Scrophularia scorodonia with their antiviral and immunomodulatory potential. This investigation presents molecular docking, molecular dynamics simulation, and free energy...
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Background Since December 2019, SARS-CoV-2 had been a significant threat globally, which has accounted for about two million deaths. Several types of research are undergoing and have reported the significant role of repurposing existing drugs and natural lead in the treatment of COVID-19. The plant Phyllanthus emblica (Synonym-Emblica officinalis)...
Article
Background and Aim Flavonoid rich plant Tephrosia purpurea (T. purpurea), commonly known as Sarpunkha have been used by different traditional system of medicine to cure diabetes mellitus. However, its effectiveness in promoting regeneration of pancreas in diabetes has not been investigated. Therefore, the present study was undertaken to evaluate th...
Article
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Background and objective: Potentilla fulgens (Rosaceae) is an edible medicinal herb which is widely used in Indian and Chinese traditional medicine for treating gastric ulcer, diabetes, cancer and diarrhea. Literature reveals that the crude ethanolic extract (EPF) of the plant possessed promising gastroprotective effects in rodents. However, the ac...
Chapter
In the current scenario of medicine, products from natural source have been significantly contributing towards the therapeutic approach in the treatment of disease ailments ranging from simple to complicated ones. The World Health Organization has stated that approximately 80% of the global population rely on herbal medicines/products for their hea...
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Bioflavonoids are the largest group of plant-derived polyphenolic compounds with diverse biological potential and have also been proven efficacious in the treatment of Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS). The present investigation validates molecular docking, simulation, and MM-PBSA studies of fiftee...
Article
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Background: Ghee is widely considered as the Indian name for clarified butterfat and processing of ghee with therapeutic herbs i.e. ghrita is renowned for augmenting their medicinal properties. Kaamdev ghrita (also known as 'VajikaranaRasayana') is cow ghee based classical Ayurvedic formulation from the aphrodisiac category, which is used to ameli...
Article
The main objective of the present investigation was to mechanistically evaluate the potency of the root extract (EEC), its bioactive chloroform fraction (CEC) and eriosematin E (ECM) isolated from Eriosema chinense against Shigella flexneri-induced sub-chronic model of infectious diarrhoea using in vitro, in vivo, and in silico methods. The in v...
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The present research work was designed to examine the neuroprotective effect of ethanolic extract of Solanum virginianum Linn. (SV) in chronic construction injury (CCI) of sciatic nerve–induced neuropathic pain in rats. The extract was initially standardized by high-performance thin-layer chromatography using solasodine as a biomarker and was then...
Article
Aim and Objective At present, the world is facing a global pandemic threat of SARS-CoV-2 or COVID-19 and till date, there are no clinically approved vaccines or antiviral drugs available for the treatment of coronavirus infections. Studies conducted in China recommended the use of liquorice (Glycyrrhiza species), an integral medicinal herb of tradi...
Article
Potentilla fulgens Wall. (Rosaceae) is a medicinal herb that is traditionally used to treat diabetes, ulcers, diarrhea, and cancer. Since the genus Potentilla bears numerous closely related species; hence, standardization of the specific species is of great importance. The present study aims to evaluate the aerial parts of P. fulgens (APPF) based o...
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The main objective of the present investigation included a comparative physicochemical, phytochemical along with chromatographic evaluation of Withania somnifera (L.) Dunal roots collected from various Indian climatic zones. The study includes macroscopical, microscopical, physicochemical, phytochemical and chromatographic evaluation of W. somnifer...
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COVID-19 has ravaged the world and is the greatest of pandemics in human history, in the absence of treatment or vaccine the mortality and morbidity rates are very high. The present investigation was undertaken to screen and identify the potent leads from the Indian Ayurvedic herb, Asparagus racemosus (Willd.) against SARS-CoV-2 using molecular doc...
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COVID-19 has ravaged the world and is the greatest of pandemics in modern human history, in the absence of treatment or vaccine, the mortality and morbidity rates are very high. The present investigation identifies potential leads from the plant Withania somnifera (Indian ginseng), a well-known antiviral, immunomodulatory, anti-inflammatory and a p...
Article
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At present, the world is facing a pandemic named as COVID-19, caused by SARS-CoV-2. Traditional Chinese medicine has recommended the use of liquorice (Glycyrrhiza species) in the treatment of infections caused by SARS-CoV-2. Therefore, the present investigation was carried out to identify the active molecule from the liquorice against different pro...
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The Public Health Emergency of International Concern declared the widespread outbreak of SARS-CoV-2 as a global pandemic emergency, which has resulted in 1,773,086 confirmed cases including 111,652 human deaths, as on 13 April 2020, as reported to World Health Organization. As of now, there are no vaccines or antiviral drugs declared to be official...
Article
Herbal drugs and their derived products play an important role in the human life due to their defensive nature against various diseases. Demand of herbal based products is continuously increasing in the society due to their less toxicity and more health value. Pure phytochemicals of plants have been placed in the modern medicine due to their health...
Article
Background Capparis decidua (Forssk.) Edgew. (Kareel) is a multifunctional perennial woody plant belongs to the family Capparaceae, widely distributed in the hot arid regions of different parts of the world especially in the Indian subcontinent, Africa and Saudi Arabia. Objective: The review aims at presenting updated information with respect to et...
Article
Ethnopharmacological relevance: The plant Psidium guajava L. (Myrtaceae), commonly used as an edible fruit is traditionally used worldwide in treatment of various gastrointestinal problems including diarrhoea. The leaves of the plant have also been evaluated for antidiarrhoeal activity in various chemical induced diarrhoea models. Objective: The...
Article
The main objective of the present study was to evaluate the potential of eriosematin E (ECM) isolated from the roots of Eriosema chinense against enteropathogenic Escherichia coli (EPEC) induced diarrhoea. ECM isolated from the bioactive chloroform fraction of E. chinense was subjected to antidiarrhoeal evaluation on rats against diarrhoea, induced...
Article
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Background: The plant Eriosema chinense Vogel (Fabaceae) is mainly found in the Eastern Himalayan regions of India and China, and its roots are used traditionally by the tribal people of Meghalaya (India) in treatment of diarrhea. Objective: The objective of the study was to evaluate the potential of roots from E. chinense against enteropathogenic...
Article
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The aim of the present study was to develop a phytochemical profile of Medohar Ark, one of the Ayurvedic formulation used as a potent tool for reducing weight in obese patients and also to perform preclinical evaluation for anti-obesity activity. The physicochemical parameters such as pH, viscosity, specific gravity and total solid content of Medoh...
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The aim of the present study was to perform a comparative phytochemical and pharmacological evaluation of organically and non-organically cultivated nutritional Centella asiatica collected at different time intervals of harvesting. The fertilizers and pesticides applied in case of organic cultivation included combination of medicinal plants along w...
Article
Ethnopharmacological relevance: The plant Solanum xanthocarpum Schrad. & Wendl. (Solanaceae) is one of the members of the dashamula (ten roots) in Ayurvedic system of medicine. The stem and fruits are used as an antipyretic, antiasthmatic and is prescribed in skin infections and for relief in burning sensation in the feet accompanied by vesicular...
Article
Background: Roots of the plant Eriosema chinense Vogel (Fabaceae) is distributed mainly over the Eastern Himalayan region of India and China. The roots of the plant are used as a vegetable by the people of Northern Australia, China and North East India and are used traditionally by the tribal people of Meghalaya (India) for the treatment of diarrh...
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Introduction: To establish the pharmacognostical and phytochemical standardization parameters of Pyrus pashia fruits in order to ensure quality and safety of this traditionally acclaimed medicinal tree. Methods: The fresh fruits of P. pashia were collected and dried. Fruit was subjected to various pharmacognostical investigations, Extraction proced...
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In Ayurveda, Leea macrophylla Roxb. ex Hornem. (Leeaceae) is indicated in worm infestation, dermatopathies, wounds, inflammation, and in symptoms of diabetes. The present study aims to determine the antioxidant and antibacterial potential of ethanolic extract and its different fractions of Leea macrophylla root tubers using phytochemical profiling...
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Objective. The whole plant of Houttuynia cordata has been reported to have potent antihyperglycemic activity. Therefore, the present study was undertaken to investigate the glucose utilization capacity of bioactive fractions of ethanol extract of Houttuynia cordata (HC) in isolated rat hemidiaphragm. Methods. All the fractions, that is, aqueous (AQ...
Data
The developed HPTLC plate was screened and photo-documented at ultra violet range with wavelength (λmax) of 254 nm. The plate was developed using Camag- HPTLC instrumentation (Camag, Mutten, Switzerland) equipped with Linomat V sample applicator, Camag TLC scanner 3, Camag TLC visualizer. (details in Supplementary data).
Article
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Objective To evaluate the aldose reductase (AR) inhibitory activity of different fractions from Houttuynia cordata (H. cordata) which used as a medicinal salad for lowering of blood sugar level. Methods AR inhibitory activity along with protein content was evaluated in vitro in rat lens. Total phenol and flavonoid contents were also determined in...
Article
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The plant Jasminum sambac L. (Oleaceae) is cultivated throughout India. The leaves and roots of the plant are used traditionally in the treatment of inflammation, fever and pain. The leaves of the plant have been reported to posses significant anti-inflammatory and analgesic activities. To scientifically validate anti-inflammatory, analgesic and an...
Article
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Objective To scientifically validate the traditional substitution of roots of highly expensive Aconitum heterophyllum (AH) with rhizomes of Cryptocoryne spiralis (CS) in the treatment of diarrhoea.Methods Different fractions from root/rhizome extract of both the plant were subjected to faecal excretion rate and castor oil-induced diarrhoea models....
Article
Context: Potentilla mooniana Wight. (Rosaceae) is a plant found in the Himalayan region where the root is traditionally used to treat stomach problems including gastric-ulcer. Objective: To scientifically validate the gastro-protective effect and derive the possible mechanistic activity of the ethanol root extract from P. mooniana (EPM). Materi...
Article
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The present review is an attempt to put an insight into a medicinal plant Houttuynia cordata Thunb, which is indigenous to North-East India and China. It is an aromatic medicinal herb belonging to family Saururaceae and is restricted to specialized moist habitats. The review provides detailed information regarding the morphology, distribution, phyt...
Article
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The roots of the plant Aconitum heterophyllum (EAH) are traditionally used for curing hysteria, throat infection, dyspepsia, abdominal pain, diabetes, and diarrhea. Therefore, the present study was undertaken to determine the mechanism involved in the anti-diarrheal activity of roots of A. heterophyllum. Ant-diarrheal activity of ethanol extract at...
Article
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Present study is an attempt to investigate plausible mechanism involved behind antidiabetic activity of standardized Houttuynia cordata Thunb. extract in streptozotocin-induced diabetic rats. The plant is used as a medicinal salad for lowering blood sugar level in North-Eastern parts of India. Oral administration of extract at 200 and 400 mg/kg dos...
Article
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Aim: Houttuynia cordata Thunb. (Saururaceae) is one of the perennial herb indigenous to North-East India and China. Despite the popular utilization of this herb as medicine, still no study has been reported so far regarding the pharmacognostical standardization. Thus, the aim of the present study was to scientifically establish a standard monograph...
Article
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Background: Potentilla mooniana Wight. (PM) (Family: Rosaceae) is a plant commonly grown at the higher altitudes (1500–3660 meter) of the lower Asian continent and is traditionally used to treat gastric and mouth disorders. The present study was aimed to scientifically develop a standard monograph for PM on the basis of pharmacognostical and phytoc...
Article
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The antidiarrhoeal activity of Cryptocoryne spiralis rhizomes extract (250, 500, 750 mg/kg, po) was evaluated using faecal excretion, castor oil-induced diarrhoea, small intestinal transit, intestinal fluid accumulation, gastric emptying and PGE2 induced enteropooling models in rats. In addition, various biochemical estimations, histopathological s...
Article
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The roots of the plant Eriosema chinense are traditionally used by the tribal people of North East India for treatment of diarrhoea. Therefore, the present investigation was undertaken to scientifically validate the traditional claim that these roots have an antidiarrhoeal effect. Ethanol extract along with three fractions, ethyl acetate, chlorofor...
Article
Full-text available
Background Roots of the plant Eriosema chinense Vogel are used as a vegetable by the people of Northern Australia and North East India. Traditionally, the roots of the plant are used for the treatment of diarrhea by the tribal people of North East India. Aim The present study was undertaken to perform quality control standardization and to evaluat...
Article
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The present investigation is an attempt to scientifically validate the traditional use of the roots of the plant Albizzia lebbeck in Ayurvedic system of medicine for curing wounds. The study included phytochemical standardization of the ethanol root extract of A. lebbeck, which was further subjected to oral acute toxicity study. Wound-healing activ...
Article
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Background & aimsPotentilla fulgens Wall. ex Hook. (PF) (Family: Rosaceae) is a shrub growing at high altitudes (1800-4350 m ASL) of the Western Himalayas. Traditionally, the roots of the plant are used to treat diabetes, peptic ulcers, diarrhoea, anthelmintic and cancer. The objective of the present study is to scientifically develop a standard mo...
Article
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Cytomorphological and physicochemical evaluations of rhizomes of Cryptocoryne spiralis, used as a substitute of Aconitum heterophyllum for treatment of diarrhea in the Indian Siddha medicine, were carried out. The study included macroscopical and microscopical description of rhizomes of plant. Physicochemical parameters including ash values, extrac...
Article
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Context: Prosopis cineraria (L.) Druce (Leguminosae), a plant of the Thar Desert of India and Pakistan is used traditionally by local people for the treatment of memory disorders and to arrest wandering of the mind. Objective: The study includes scientific validation of P. cineraria for nootropic activity. To elucidate the possible mechanism, th...
Article
Objective: To isolate the mangiferin fromMangifera indica (M. indica)and assess the antimicrobial activity of different analogues synthesized from mangiferin. Methods: Mangiferin was isolated by column chromatography from the ethanolic extract of stem bark of M. indica. Mangiferin was further converted to 5-(N-phenylamino methyleno)mangiferin, 5...
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The present study includes macroscopical as well as microscopical description of the plant Melothria maderaspatana Linn., along with determination of various physicochemical parameters, such as different ash values, extractive values, and fluorescence drug analysis. Preliminary phytochemical screening along with quantification of total phenolic and...
Article
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Harmine, a beta-carboline alkaloid, is widely distributed in the plants, marine creatures, insects, mammalians as well as in human tissues and body fluids. Harmine was originally isolated from seeds of Peganum harmal in 1847 having a core indole structure and a pyridine ring. Harmine has various types of pharmacological activities such as antimicro...