Doug Hyun Han

Doug Hyun Han
Chung-Ang University · Department of Psychiatry

MD, PhD

About

263
Publications
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6,244
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Publications

Publications (263)
Article
This case report aimed to discuss the efficacy of aripiprazole for dyskinesia in patients with functional movement disorder after streptococcal infection, with its biological action of modulating dopamine hyperactivity in the basal ganglia as a dopamine partial agonist. This report has shown that the [18F] N -(3-Fluoropropyl)-2β-carbon ethoxy-3β-(4...
Article
Introduction Over 80% of perimenopausal women experience various physical and neuropsychiatric symptoms due to changes in female hormones. However, accurate evaluation and treatment of menopausal symptoms are lacking due to limited evidence regarding customized treatment for each symptom type. This study aimed to identify and cluster psychosomatic...
Article
Objective: Facial affect recognition is associated with neuropsychological status and psychiatric diseases. We hypothesized that facial affect recognition is associated with psychological status and perception of other affects. Methods: A total of 80 images depicting facial affect, including 20 Neutral, 20 Angry, 20 Fear, and 20 Sad, were screen...
Article
The purpose of this study was to investigate effects of brain excitability by transcranial direct current stimulation (tDCS) on spike performances of professional female volleyball players. Thirteen professional female volleyball players were recruited for participation. We performed a randomized single-blind, SHAM-stimulus controlled, and counter-...
Preprint
BACKGROUND Virtual reality has been suggested to be effective in enhancing physical exercise because of its immersive characteristics. However, few studies quantitatively assessed motion and brain activity during virtual reality exercises. OBJECTIVE We hypothesized that virtual reality could stimulate body movement and brain activity more effectiv...
Article
Objective: This study aimed to evaluate whether somatic symptoms in adolescents with attention deficit hyperactivity disorder (ADHD) are associated with a dissociative pattern of functional connectivity (FC) within the default mode network (DMN) and whether methylphenidate administration can improve clinical and somatic symptoms. We also evaluated...
Article
Objective: During the coronavirus disease (COVID-19) pandemic, several studies have found that Internet usage and gaming times have increased among adolescents. Parents' Internet literacy and attitudes toward Internet gaming have been reported to affect children's Internet gaming disorder (IGD). We hypothesized that parents' attitudes toward Inter...
Article
Background: Smartphone use patterns may predict daily life efficacy and performance improvements in sports. Additionally, personal characteristics may be associated with smartphone overuse. Methods: We investigated the correlation between the temperament and character inventory (TCI) and academic performance using smartphone log data. We hypothe...
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Deficits in color vision and related retinal changes hold promise as early screening biomarkers in patients with Alzheimer’s disease. This study aimed to determine a cut-off score that can screen for Alzheimer’s dementia using a novel color vision threshold test named the red, green, and blue (RGB) modified color vision plate test (RGB-vision plate...
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Objective: This study aims to empirically determine if indirect exposure to client violence has significant negative effects on social workers' posttraumatic stress disorder (PTSD) the same way direct victimization does. Methods: Using a sample of 1,359 social workers drawn from the data collected by the Seoul Association of Social Workers, this...
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Background: Education on internet games for parents and internet game literacy are needed to prevent problematic internet game playing in Korea. We created an 18-item Internet Game Literacy Scale (IGLS). It is a valuable tool for assessing the positive and negative aspects of internet game play. We aimed to determine the validity of the IGLS and t...
Article
Background and objectives: Digital therapeutics are an emerging type of medical therapy and are defined as evidence-based therapeutic interventions for patients by means of qualified software programs to prevent, manage, or treat medical conditions. Today, digital therapeutics products are on the market or under development for a wide range of med...
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A close link has been established between self-harm and suicide risk in adolescents, and increasing attention is given to social media as possibly involved in this relationship. It is important to identify indicators of suicidality (i.e., suicide ideation or attempt) including aspects related to contagion in online and offline social networks and e...
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Olfactory impairment is associated with dementia and is a potential early biomarker of cognitive decline. We developed a novel olfactory threshold test called Sniff Bubble using rose odor-containing beads made with 2-phenylethyl alcohol. We aimed to define cut-off scores for this tool to help identify cognitive decline among elderly people. In tota...
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Objective: In somatic symptom disorder (SSD), cognitive dysfunction is related to perceptive distortion that excessively amplifies bodily sensations. The association between high body mass index (BMI) and cognitive dysfunction could be attributed to underlying systemic inflammation. We aimed to evaluate whether patients with SSD and high BMI exhib...
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Smartphone app-use patterns will predict professional golfers’ athletic performance, and the use time of serious apps would be associated with improved performance. This longitudinal 4-week observation of 79 professional golfers assessed golf handicaps and smartphone app-use patterns at the start of the Korean professional golf season and 2 and 4 w...
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Objective We aimed to identify differences in brain functional connectivity (FC) and characteristics of body sensation between sports players and patients with somatic symptom disorder (SSD), in order to investigate the neurobiological basis of SSD. Methods Thirty-five sports players (SPORTS group), 36 patients with SSD (SOM group), and 33 healthy...
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Introduction: The results of studies comparing the characteristics of Internet gaming with those of Internet gambling have been controversial. We hypothesized that problematic web-based board gaming behaviors are associated with psychological and social interaction factors. We also hypothesized that non-problematic adolescent Internet gaming is a p...
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Introduction: Complex post-traumatic stress disorder (C-PTSD) is characterized by the typical symptoms of PTSD, in addition to affective dysregulation, negative self-concept, and disturbances in interpersonal relationships. Children and adolescents with C-PTSD have been reported to have deficits in emotional and cognitive functions. We hypothesized...
Preprint
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BACKGROUND Stress management within the workplace is important for a healthy mental and physical state. Due to technological advancements, individual-tailored therapy as well as online cognitive-behavioral therapy (CBT) is on the rise. OBJECTIVE This study analyzed the efficacy of a smartphone application based on third-wave CBT tailored to the in...
Article
Background: Stress management in the workplace is essential for a healthy mental and physical state. Due to technological advancements, individually tailored therapy and online cognitive behavioral therapy (CBT) are on the rise. Objective: This study analyzed the efficacy of a smartphone app based on third-wave CBT tailored to an individual. Me...
Article
Background: Although attention-deficit/hyperactivity disorder (ADHD) symptoms were identified as a key risk factor for Internet gaming disorder (IGD), the effect of ADHD comorbidity on longitudinal course of IGD in the clinical population remains to be further examined. This study aimed to investigate whether ADHD comorbidity in IGD patients affec...
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The purpose of this study was to compare the characteristics of suicide attempts by drug overdose between young people and adults, and evaluate the cost-effectiveness of a multi-disciplinary emergency consultation system (MECS) for suicide attempters with drug overdose. It was verified by comparing and analyzing data from June 1, 2017 to May 31, 20...
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Objective There is an updated conceptualization of whole-lifespan attention-deficit hyperactivity disorder (ADHD), promoted by awareness of probable persistence of impairment into adulthood. We investigated cognition trajectories from adolescence to mid-adulthood in ADHD. Method Data of 240 patients with ADHD and 244 healthy controls (HCs) were ob...
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Background Methylphenidate improves clinical symptoms and brain activity in attention deficit disorder (ADHD) patients through the attention-regulation network's dopamine system. Additionally, water-soluble extracts (HX106) of four plants (Gastrodia elata Blume, Liriope platyphylla Wang et Tang, Salvia miltiorrhiza Bunge, and Dimocarpus longan Lour...
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Background The emotional perception test is considered an effective tool in differentiating between schizophrenia and bipolar disorder. We hypothesized that schizophrenic patients would show decreased emotional perception ability compared with bipolar patients and that the disrupted emotional perception ability would be associated with the disrupte...
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Background: This study aimed to develop a simple and one-off olfactory screening test, the sniffing bead system, for general clinical use in older adults. Methods: In this cross-sectional study, geriatric subjects (aged > 50 years) who underwent neurocognitive and olfactory function tests were included. Overall, 137 subjects were enrolled, and t...
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Bitcoin has unique characteristics that have inspired people to invest in it as well as distinct drawbacks. With a rapid increase in Bitcoin prices in the short term, more investors enthusiastically began investing in it, raising concerns about a speculative bubble. This study investigated the multiple factors involved in the Bitcoin craze despite...
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Among olfactory functions, odor identification is the most studied predictor of dementia. We aimed to verify whether patients with dementia are less aware of specific odors than cognitively normal individuals using an odor identification test, which includes odorants that are culturally familiar to South Koreans. We divided 139 older adults aged 57...
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Objective: We aimed to find the optimal cut-off scores for screening of odor detection threshold, odor discrimination, and odor identification tests for detection of mild cognitive impairment (MCI) and dementia in Korean elderly. Methods: A total of 195 elderly people were divided into three groups: the normal cognition (NC), MCI, and dementia g...
Article
This study aimed to determine the neurophysiological mechanisms underlying the effects of aerobic exercise, which influence brain O2 consumption, on cognitive enhancement. Sixteen healthy men were asked to complete a 2-back test at rest and after moderate and high-intensity aerobic exercise. During the 2-back test, hemodynamic changes within the pr...
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Background: This study was to assess the validity of the Korean version of the semi-structured Diagnostic Interview for Adult ADHD, third edition (DIVA-5). The secondary aim was to compare sociodemographic and psychiatric comorbidities in adult patients with and without a diagnosis of ADHD. Methods: A total of 279 participants were recruited fro...
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Objective: We sought to determine if the links between and within the default mode network (DMN) and dorsal attention network (DAT) exhibited different conditions according to catechol-O-methyltransferase (COMT) gene polymorphism in relationship to attention-deficit hyperactivity disorder (ADHD) symptoms. Methods: Fifty-seven children with ADHD...
Preprint
BACKGROUND This study proposes a digital program for the treatment of mental illness that could increase motivation and learning outcomes for patients. Several studies already applied this method by using an exposure and response prevention inspired serious game to treat patients with obsessive compulsive disorder (OCD). OBJECTIVE We hypothesized...
Article
Background This study proposes a digital program for the treatment of mental illness that could increase motivation and improve learning outcomes for patients. Several studies have already applied this method by using an exposure and response prevention–inspired serious game to treat patients with obsessive-compulsive disorder (OCD). Objective We...
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This study investigated differences in perfectionist traits and commitment between professional and amateur golfers, as well as correlations among perfectionist traits, commitment, and golf handicap. Using simple random sampling, 486 professional golfers (mean age = 22.1 ± 3.0, 52.1% female) and 233 amateur golfers (mean age = 44.8 ± 10.2, 55.8% fe...
Preprint
Full-text available
Background In the current coronavirus disease pandemic situation, the need for quick, simple, and one-off olfactory function screening test has increased. This study aimed to develop a simple and one-off olfactory screening test, the sniffing bead system, for general clinical use in older adults. Methods In this prospective cross-sectional study,...
Preprint
Full-text available
Background: This study aimed to develop a simple and one-off olfactory screening test, the sniffing bead system, for general clinical use in older adults. Methods: In this cross-sectional study, geriatric subjects (aged > 50 years) who underwent neurocognitive and olfactory function tests were included. Overall, 137 subjects were enrolled, and the...
Preprint
Full-text available
Background: This study aimed to develop a simple and one-off olfactory screening test, the sniffing bead system, for general clinical use in older adults. Methods: In this cross-sectional study, geriatric subjects (aged > 50 years) who underwent neurocognitive and olfactory function tests were included. Overall, 137 subjects were enrolled, and the...
Preprint
Full-text available
Background: This study aimed to develop a simple and one-off olfactory screening test, the sniffing bead system, for general clinical use in older adults. Methods: In this cross-sectional study, geriatric subjects (aged > 50 years) who underwent neurocognitive and olfactory function tests were included. Overall, 137 subjects were enrolled, and the...
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Full-text available
Background: This study aimed to evaluate the therapeutic effect of repetitive transcranial magnetic stimulation (rTMS) as a nonpharmacologic treatment in depressed hemodialysis patients. Methods: Patients who scored ≥ 5 on the Patient Health Questionnaire-9 were randomized to either the rTMS (n = 7) or sham group (n = 7). The rTMS group was stim...
Article
The goal of this study was to examine if motor timing training alters the variability of the upper extremity movement during the golf putt. To improve motor timing, we utilised Interactive Metronome (IM), a software program that is designed to improve the rhythm and timing of intrinsic movements. Twenty participants who were registered in the Korea...
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The esports industry is increasing in popularity and is now played at the professional level. We hypothesized that esports players may have a significant advantage over the general population in terms of psychological and cognitive characteristics, which may be similar to that of professional baseball players. We recruited three participant groups:...
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Disrupted reward circuits and diminished behavioural control have been suggested as the pathophysiologies of Internet gaming disorder (IGD). Family functioning is thought to play an important role in reward-related control. We hypothesized that adolescents with IGD show disrupted patterns of family relationships, which are associated with brain act...
Article
The aims of this study were to examine the relationship between Internet gaming disorder (IGD) and gaming disorder (GD) and the degree of concordance between treatment seeking for gaming and IGD/GD. One hundred gamers who sought treatment for their gaming were compared with one hundred gamers who never sought treatment and gamers who met IGD and/or...
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Olfactory impairment occurs in patients with Alzheimer's disease, and olfactory function tests are performed for the diagnosis of Alzheimer's disease. However, the diagnosis and patient status are not currently outlined for vascular dementia, and many physicians do not consider concurrent vascular dementia in patients complaining of olfactory dysfu...
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Background Internet gaming disorder (IGD) is commonly comorbid with attention-deficit/hyperactivity disorder (ADHD). Although the addiction is more severe when comorbid with ADHD, little is known about the neural correlates of the association. This study aimed to identify whether an ADHD-related structural brain network exists in IGD patients with...
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Purpose We aimed to evaluate the effect and neurophysiological mechanism of physical exercise intervention combined with cognitive behavioral therapy on mood and frontal alpha asymmetry in the treatment of Internet gaming disorder. Methods Fifty male adolescents with Internet gaming disorder were randomly assigned to one of two groups. In the cogn...
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Objective: Our previous study suggested that monitoring online board gamers may be an efficient approach to curb illegal gambling. We aimed to invent and validate a behavioral scale for assessing the risk of problematic web-based board gaming. Methods: The sample included 300 Korean adults, representing a response rate of 3.1%. All participants...
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Objective: Coping can be defined as the reactions to harm or distress individuals take to reduce stress. This study aimed to determine how an individual's temperament and character is correlated with the person's main coping method. Methods: The Korean version of the Ways of Coping Questionnaire and Temperament and Character Inventory-Revised-Sh...
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While pro-gamers play according to defined living habits and planned schedules, adolescents with internet gaming disorder (IGD) exhibit irregular lifestyles and unregulated impulsive gaming behavior. Fourteen IGD adolescents and 12 pro-gaming students participated in this study. At baseline and after one year, demographic data, the Child Behavior C...
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Objectives: Adult attention-deficit/hyperactivity disorder (ADHD) is an important mental health problem that needs resolution, especially considering the high rates of ADHD continuation from childhood to adolescence/adulthood and the high prevalence of ADHD in adults. Adults with ADHD have lifelong negative impacts and require close monitoring wit...
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Cognitive behavioral therapy (CBT) is considered to be an effective treatment for internet gaming disorder (IGD). This study examined the effectiveness of CBT in treating impulsivity, anxiety, avoidance, and family and environmental problems in patients. A total of 101 patients completed the CBT program and 104 completed supportive therapy. The CBT...
Article
Objective: We aimed to understand whether Attention Deficit Hyperactivity Disorder (ADHD) and Internet gaming disorder (IGD) share similar brain functional connectivity (FC) between the frontal and subcortices. Method: We compared changes in clinical symptoms and brain activity using functional magnetic resonance imaging (fMRI) in 26 patients with...
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This study investigated protective and risk factors for depressive mood and anxiety against occupational stress, including temperament character and coping strategy, among civil servants. We administered a questionnaire that included demographic factors and psychological scales to 1197 Korean civil servants. High levels of occupational stress, temp...
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Introduction: Previous studies on internet gaming disorder (IGD) have reported an association between personality traits and impulsive or problematic use of the internet or internet games, but the results obtained were inconsistent. Our study’s hypothesis was that personality traits are associated with the individual’s choice to play internet games...
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Objective: Korea (ranked 16th) and Japan (ranked 13th) show similar rankings, skills, and performance in basketball. However, the countries differ in size and the number of players in the national women's basketball system. The current study aimed to compare the psychological factors (anxiety, and temperament and character) and the national teams'...
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Objective: Synaptic vesicle mobilization and neurite outgrowth regulation molecules were examined in modulation of effects of methylphenidate (MPH) in Spontaneous Hypertensive Rats (SHRs), a model for attention-deficit hyperactivity disorder (ADHD). Methods: We compared the changes in the protein expression level of Cyclin dependent kinase 5 (Cd...
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Background We assessed implicit and explicit emotion in older patients with dementia using biosignals. Methods Fifty patients with dementia and 34 healthy individuals watched 3 videos that aimed to elicit various emotional responses. Electroencephalogram and heart rate variability were recorded. Results Patients with dementia experienced less fun...
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Background and objective: Patients with mood disorders are known to have an emotion recognition deficit in facial emotion processing. Emotion perception involves two systems of cognitive and affective processes associated with brain activation in the fusiform gyrus and prefrontal cortices. To overcome the limitations of existing emotion perception...
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Background: Studying immigrants may have the potential to explore how cultural and environmental changes affect the internet game play patterns of individuals in the two countries. We planned to compare risk and preventive factors for Internet Gaming Disorder (IGD) between Korean adolescents in Korea and immigrant Koreans in the US. Methods: Nin...