Dory Abelman

University of Toronto | U of T · Department of Medical Biophysics

Introduction Accurate detection of minimal residual disease (MRD) is crucial for evaluating treatment efficacy in multiple myeloma (MM), yet current methods are invasive and often limited by bone marrow (BM) sample quality. We therefore compared standard MRD detection methods to whole-genome sequencing (WGS) of peripheral blood plasma cell-free DNA...

Introduction: Molecular profiling of bone marrow (BM) tumor cells in multiple myeloma (MM) can be limited by low tumor cell content for analysis by multiple assays. We therefore evaluated the concordance of molecular profiles of cancer cells enriched from BM versus cell-free DNA (cfDNA) derived from peripheral blood (PB) and BM plasma collected at...

Genomic characterization of cancer has enabled identification of numerous molecular targets, which has led to significant advances in personalized medicine. However, with few exceptions, precision medicine approaches in the plasma cell malignancy multiple myeloma (MM) have had limited success, likely owing to the subclonal nature of molecular targe...

Improving the efficiency and sustainability of Canada’s healthcare system is currently being prioritized by the federal government. In order to achieve this, government and non-government stakeholder collaboration will be required to improve integration, universality, and equity for all populations throughout the country. Although technological inn...

Considering both the high monetary and emotional costs associated with caring for patients afflicted with depression, it is apparent that health professionals should find effective treatments to ensure that interventions are both cost effective and risk-reducing. While exercise is generally known to be important in maintaining general health and we...

As postsecondary students' use of "study drugs" becomes more popular with increasingly reported negative effects on health and academic performance, failing prohibitionist policies to reduce consumption, and ambiguity in literature towards best practices to address this population, we present a literature review that seeks effective solutions educa...

Executive Summary This report summarizes results of an assessment survey conducted with students in the School of Health Studies (SHS) at Western University. The purpose of the survey was twofold: 1. to determine general interest in study abroad among SHS students 2. to determine specific student interest, preferred outcomes and financial capacity...

Undergraduate students are becoming increasingly involved in research. They already posses the skills required to make meaningful contributions to their field of interest. Some important components of their success relates to a student's ability to stay up to date in the research of their field, and to learn practical skills pertaining to the publi...