Dongdong Chen

The University of Edinburgh | UoE · School of Engineering

Multi-modality image fusion is a technique used to combine information from different sensors or modalities, allowing the fused image to retain complementary features from each modality, such as functional highlights and texture details. However, effectively training such fusion models is difficult due to the lack of ground truth fusion data. To ad...

Solving an ill-posed linear inverse problem requires knowledge about the underlying signal model. In many applications, this model is a priori unknown and has to be learned from data. However, it is impossible to learn the model using observations obtained via a single incomplete measurement operator, as there is no information about the signal mod...

From early image processing to modern computational imaging, successful models and algorithms have relied on a fundamental property of natural signals: symmetry . Here symmetry refers to the invariance property of signal sets to transformations, such as translation, rotation, or scaling. Symmetry can also be incorporated into deep neural networks...

In many real-world inverse problems, only incomplete measurement data are available for training which can pose a problem for learning a reconstruction function. Indeed, unsupervised learning using a fixed incomplete measurement process is impossible in general, as there is no information in the nullspace of the measurement operator. This limitatio...

From early image processing to modern computational imaging, successful models and algorithms have relied on a fundamental property of natural signals: symmetry. Here symmetry refers to the invariance property of signal sets to transformations such as translation, rotation or scaling. Symmetry can also be incorporated into deep neural networks in t...

Solving a linear inverse problem requires knowledge about the underlying signal model. In many applications, this model is a priori unknown and has to be learned from data. However, it is impossible to learn the model using observations obtained via a single incomplete measurement operator, as there is no information outside the range of the invers...

In many real-world settings, only incomplete measurement data are available which can pose a problem for learning. Unsupervised learning of the signal model using a fixed incomplete measurement process is impossible in general, as there is no information in the nullspace of the measurement operator. This limitation can be overcome by using measurem...

Magnetic Resonance Fingerprinting (MRF) has emerged as a promising quantitative MR imaging approach. Deep learning methods have been proposed for MRF and demonstrated improved performance over classical compressed sensing algorithms. However many of these end-to-end models are physics-free, while consistency of the predictions with respect to the p...

Deep networks provide state-of-the-art performance in multiple imaging inverse problems ranging from medical imaging to computational photography. However, most existing networks are trained with clean signals which are often hard or impossible to obtain. Equivariant imaging (EI) is a recent self-supervised learning framework that exploits the grou...

In various imaging problems, we only have access to compressed measurements of the underlying signals, hindering most learning-based strategies which usually require pairs of signals and associated measurements for training. Learning only from compressed measurements is impossible in general, as the compressed observations do not contain informatio...

Deep convolutional neural networks (CNNs) have emerged as a new paradigm for Mammogram diagnosis. Contemporary CNN-based computer-aided-diagnosis systems (CADs) for breast cancer directly extract latent features from input mammogram image and ignore the importance of morphological features. In this paper, we introduce a novel end-to-end deep learni...

In various imaging problems, we only have access to compressed measurements of the underlying signals, hindering most learning-based strategies which usually require pairs of signals and associated measurements for training. Learning only from compressed measurements is impossible in general, as the compressed observations do not contain informatio...

Computer-aided breast cancer diagnosis in mammography is a challenging problem, stemming from mammographical data scarcity and data entanglement. In particular, data scarcity is attributed to the privacy and expensive annotation. And data entanglement is due to the high similarity between benign and malignant masses, of which manifolds reside in lo...

Deep learning is emerging as a new paradigm for solving inverse imaging problems. However, the deep learning methods often lack the assurance of traditional physics-based methods due to the lack of physical information considerations in neural network training and deploying. The appropriate supervision and explicit calibration by the information of...

Consistency of the predictions with respect to the physical forward model is pivotal for reliably solving inverse problems. This consistency is mostly un-controlled in the current end-to-end deep learning methodologies proposed for the Magnetic Resonance Fingerprinting (MRF) problem. To address this, we propose PGD-Net, a learned proximal gradient...

Deep convolutional neural networks (CNNs) have emerged as a new paradigm for Mammogram diagnosis. Contemporary CNN-based computer-aided-diagnosis (CAD) for breast cancer directly extract latent features from input mammogram image and ignore the importance of morphological features. In this paper, we introduce a novel deep learning framework for mam...

Deep learning is emerging as a new paradigm for solving inverse imaging problems. However, the deep learning methods often lack the assurance of traditional physics-based methods due to the lack of physical information considerations in neural network training and deploying. The appropriate supervision and explicit calibration by the information of...

Deep learning is emerging as a new paradigm for solving inverse imaging problems. However, the deep learning methods often lack the assurance of traditional physics-based methods due to the lack of physical information considerations in neural network training and deploying. The appropriate supervision and explicit calibration by the information of...

Consistency of the predictions with respect to the physical forward model is pivotal for reliably solving inverse problems. This consistency is mostly un-controlled in the current end-to-end deep learning methodologies proposed for the Magnetic Resonance Fingerprinting (MRF) problem. To address this, we propose ProxNet, a learned proximal gradient...

Consistency of the predictions with respect to the physical forward model is pivotal for reliably solving inverse problems. This consistency is mostly uncontrolled in the current end-to-end deep learning methodologies proposed for the Magnetic Resonance Fingerprinting (MRF) problem. To address this, we propose PGD-Net, a learned proximal gradient d...

Catastrophic forgetting is a chronic problem during the online training process of deep neural networks. That is, once a new data set is used to train an existing neural network, the network will lose the ability to recognize the original data set. In literature, online contrastive divergence (CD) with generative replay (GR) exploits the generative...

Small-sample learning involves training a neural network on a small-sample data set. An expansion of the training set is a common way to improve the performance of neural networks in small-sample learning tasks. However, improper constraints in expanding training data will reduce the performance of the neural networks. In this article, we present c...

Magnetic Resonance Fingerprinting (MRF) methods typically rely on dictionary matching to map the temporal MRF signals to quantitative tissue parameters. These methods suffer from heavy storage and computation requirements as the dictionary size grows. To address these issues, we proposed an end to end fully convolutional neural network for MRF reco...

Computer-aided breast cancer diagnosis in mammography is limited by inadequate data and the similarity between benign and cancerous masses. To address this, we propose a signed graph regularized deep neural network with adversarial augmentation, named DiagNet. Firstly, we use adversarial learning to generate positive and negative mass-contained mam...

We study a deep learning approach to address the heavy storage and computation re-quirements of the baseline dictionary-matching (DM) for Magnetic Resonance Fingerprint-ing (MRF) reconstruction. The MRF-Net provides a piece-wise affine approximation to the (temporal) Bloch response manifold projection. Fed with non-iterated back-projected images, t...

This work proposes an end-to-end deep fully convolutional neural network for MRF reconstruction (MRF-FCNN), which firstly employs linear dimensionality reduction and then uses a neural network to project the data into the tissue parameters. The MRF dictionary is only used for training the network and not during image reconstruction. We show that MR...

Computer-aided breast cancer diagnosis in mammography is limited by inadequate data and the similarity between benign and cancerous masses. To address this, we propose a signed graph regularized deep neural network with adversarial augmentation, named \textsc{DiagNet}. Firstly, we use adversarial learning to generate positive and negative mass-cont...

We present, for the first time, a novel deep neural network architecture called DUALCORENET with a dual-path connection between the input image and output class label for mammogram image processing. This architecture is built upon U-Net, which non-linearly maps the input data into a deep latent space. One path of the DUALCORENET, the locality prese...

Manifold learning (ML) is a research topic of great interest in the field of machine learning that aims to determine the appropriate low-dimensional embeddings of data. The embeddings should preserve the intrinsic structure of the data manifold. Many ML techniques have been proposed to learn the underlying manifold of data. It is crucial to effecti...

We present, for the first time, a novel deep neural network architecture called \dcn with a dual-path connection between the input image and output class label for mammogram image processing. This architecture is built upon U-Net, which non-linearly maps the input data into a deep latent space. One path of the \dcnn, the locality preserving learner...

We explore the use of deep learning for breast mass segmentation in mammograms. By integrating the merits of residual learning and probabilistic graphical modelling with standard U-Net, we propose a new deep network, Conditional Residual U-Net (CRU-Net), to improve the U-Net segmentation performance. Benefiting from the advantage of probabilistic g...

Current popular methods for Magnetic Resonance Fingerprint (MRF) recovery are bottlenecked by the heavy storage and computation requirements of a matched-filtering step due to the growing size and complexity of the fingerprint dictionaries in multi-parametric quantitative MRI applications. In this abstract we investigate and evaluate advantages of...

We investigate the potential of a restricted Boltzmann Machine (RBM) for discriminative representation learning. By imposing the class information preservation constraints on the hidden layer of the RBM, we propose a Signed Laplacian Restricted Boltzmann Machine (SLRBM) for supervised discriminative representation learning. The model utilizes the l...

We explore the use of deep learning for breast mass segmentation in mammograms. By integrating the merits of residual learning and probabilistic graphical modelling with standard U-Net, we propose a new deep network, Conditional Residual U-Net (CRU-Net), to improve the U-Net segmentation performance. Benefiting from the advantage of probabilistic g...

In this paper, we propose a novel deep manifold clustering (DMC) method for learning effective deep representations and partitioning a dataset into clusters where each cluster contains data points from a single nonlinear manifold. Different from other previous research efforts, we adopt deep neural network to classify and parameterize unlabeled dat...

The local neighborhood selection plays a crucial role for most representation based manifold learning algorithms. This paper reveals that an improper selection of neighborhood for learning representation will introduce negative components in the learnt representations. Importantly, the representations with negative components will affect the intrin...

The local neighborhood selection plays a crucial role for most representation based manifold learning algorithms. This paper reveals that an improper selection of neighborhood for learning representation will introduce negative components in the learnt representations. Importantly, the representations with negative components will affect the intrin...