Dohbit Julius Sama

• MD, DSSC
• Research Director at University of Yaoundé I

Accessory or ectopic breast tissue is an anomaly in the development of the breast. It is a rare condition that occurs along the embryological mammary line. In less than 1% of all breast cancers, supernumerary breast cancer is reported , with the axillary location being the most common in 60% to 90% of cases. Cancerous degeneration of this supernume...

Introduction: The purpose of this study was to explore the clinical presentation, differential diagnosis, treatment, and prognosis of bipolar disorder in children and adolescents. Methodology: The authors reviewed two clinical cases of patients with symptoms of bipolar disorder with rapid cycling. Medical history, symptoms and treatment were docume...

This paper analyzes a randomized controlled trial of a personalized digital counseling intervention addressing informational constraints and choice architecture, cross-randomized with discounts for long-acting reversible contraceptives (LARCs), such as intrauterine devices (IUDs). The counseling intervention encourages shared decision-making (SDM)...

Introduction: the purpose of this study was to identify factors associated with the failure of medical treatment for ectopic pregnancy (EP) in women at the Yaoundé Gynaecology, Obstetrics and Pediatrics Hospital. Methods: we conducted a case-control study using a retrospective data collection over a 10-year period from January 1st 2008 to Decemb...

Objective: To analyze the epidemiological aspects of invasive cervical cancer according to HIV status. Methods: This was an historical cohort study from January 2010 to April 2017 in three hospitals at the Yaoundé city Capital, Cameroon, after the National Ethics Committee' approval. We included invasive cervical cancers with documented HIV stat...

Background Safe childbirth remains a daunting challenge, particularly in low-middle income countries, where most pregnancy-related deaths occur. Cameroon’s maternal mortality rate, estimated at 529 per 100,000 live births in 2017, is significantly high. The WHO Safe Childbirth Checklist (SCC) was designed to improve the quality of care provided to...

Introduction Placenta accreta spectrum is a major obstetric disorder that is associated with significant morbidity and mortality. The objective of this study is to establish a prediction model of clinical outcomes in these women Materials and methods PAS-ID is an international multicenter study that comprises 11 centers from 9 countries. Women who...

Objective: To compare peripartum outcomes of uterus preserving procedures to caesarean hysterectomy in women with placenta accreta spectrum (PAS), and to identify risk factors associated with adverse maternal outcomes. Design: Retrospective study (ClinicalTrials.gov identifier: NCT04384510) Setting:11 tertiary centres from 9 countries Population or...

Uterine fibroid is the most encountered benign tumour in women of reproductive age. It causes spontaneous abortions, missed abortions, painful red degeneration or infarction of the fibroids, abnormal foetal presentation, obstructed labour, and an increased likelihood of premature deliveries, caesarean deliveries, postpartum haemorrhage in pregnancy...

The Yaoundé Gynaeco-Obstetric and Pediatric Hospital (YGOPH) faced challenges of high debts and sub-optimal care delivery. Performance-Based-Management (PBM) provides an environment of checks and balances, increased transparency, competition and autonomy, thereby improving clinical as well as financial indicators. We describe the transition from re...

Background: In the environment, there’s not enough studies on the effects of sexual activity during pregnancy on labor outcome, especially for nulliparous women. The aim was to assess the effects of sexual activity during the third term of pregnancy on the outcome of labor in nulliparous women.Methods: A prospective cohort study on labor was carrie...

Introduction: Acute pelvic pain is an important cause of morbi-mortality. The purpose of this study was to describe the epidemiological, clinical and therapeutic features of acute pelvic pain in Yaoundé. Methods: We conducted a cross-sectional, descriptive study with collection of prospective data in the Department of Gynecology and Obstetrics a...

Introduction: Anemia is a global problem affecting 41.8% of pregnant women. Iron deficiency is the leading cause during pregnancy. Its prevalence among Cameroonian pregnant women was estimated at 50.9% in 2004. Few studies have evaluated women's adherence to iron supplementation prescribed during pregnancy. We carried this study in order to evalua...

Background: Safe childbirth remains a daunting challenge, particularly in low-resource settings where most pregnancy-related deaths occur. Cameroon’s maternal mortality rate, estimated at 782 per 100,000 live births in 2011 is significantly high. Adherence to good practice standards by birth attendants is key to improving pregnancy outcomes. The WH...

Background: Safe childbirth remains a daunting challenge, particularly in low-resource settings where most pregnancy-related deaths occur. Cameroon’s maternal mortality rate, estimated at 782 per 100,000 live births in 2011 is significantly high. Adherence to good practice standards by birth attendants is key to improving pregnancy outcomes. The WH...

Background: Safe childbirth remains a daunting challenge, particularly in low-resource settings where most pregnancy-related deaths occur. Cameroon’s maternal mortality rate, estimated at 782 per 100,000 live births in 2011 is significantly high. Adherence to good practice standards by birth attendants is key to improving pregnancy outcomes. The WH...

Background: Safe childbirth remains a daunting challenge, particularly in low middle income countries, where most pregnancy-related deaths occur. Cameroon’s maternal mortality rate, estimated at 529 per 100,000 live births in 2017 is significantly high. Adherence to essential birth practices by birth attendants is key to improving pregnancy outcome...

Background: Safe childbirth remains a daunting challenge, particularly in low middle-income countries, where most pregnancy-related deaths occur. Cameroon's maternal mortality rate, estimated at 529 per 100,000 live births in 2017 is significantly high. The WHO Safe Childbirth Checklist (SCC) was designed to improve the quality of care provided to...

Background: Tocolysis aims to prolong pregnancy by stopping labor to achieve lung maturation. Failure of tocolysis is a common situation in obstetrics with its share of risks and complications for the fetus.Objective: To identify the determinants of tocolysis failure in two Hospitals in Yaounde.Patients and methods: We carried out a case-control st...

Introduction: Cervical cancer remains one of the leading health hazards affecting a majority women across the globe. The situation is even more, preoccupying particularly in areas where screening programmes and services are absent. The World Health Organization (WHO) says "cervical cancer is the fourth most frequent cancer in women, with an estima...

Objective In Africa, 80% of women ingest traditional medicine (TM) during pregnancy. Although widely used in Cameroon, no study in has either demonstrated its safety or effectiveness. Hence, we sought to determine the effects of TM ingestions during the peri-partum period on maternal and foetal outcomes. A cohort study was conducted from January to...

Background: Uterine fibroids are the most common uterine tumours in females of reproductive age. During pregnancy, uterine fibroids may be complicated by aseptic necrobiosis. We herein report an ambiguous clinical presentation of uterine fibroids in pregnancy and discuss the diagnostic challenges encountered in our resource-constraint setting. Cas...

Objective To identify the risk factors for ectopic pregnancy (EP) in a population of Cameroonian women. Sample and methods We performed a matched case-control study; 88 women with diagnosed EP (cases), and 176 women with first trimester intrauterine pregnancy (IUP) (controls), who underwent questionnaires. Odds Ratio (OR) and 95% confidence interv...

Introduction Teenage pregnancy is a social problem in Cameroon in general and in Kumbo East in particular. This results in physical, psychological and socio-economic consequences on the teenage mother, family and the society as a whole. In spite of studies and interventions that have been and are being implemented, the prevalence of unplanned teena...

Background There are increasing reports of term live abdominal pregnancies even though the diagnosis of abdominal pregnancy is made preoperatively only in 45% of cases which partly explains the high maternal and perinatal morbidity and mortality associated with abdominal pregnancy. Case Report We report a rare case of misdiagnosed term abdominal p...

Le taux d'utérus cicatriciel, facteur de risque établi de la morbidité obstétricale augmente à travers le monde. Dans les pays en développement, les ruptures sur utérus non cicatriciel peuvent constituer 87,4% des cas. Sa prise en charge demeure ainsi une problématique de l'obstétrique moderne, notamment dans ces pays. L'objectif était de décrire l...

Objective: To identifie the risk factors for ectopic pregnancy in a population of Cameroonian women Sample and methods: We wil perform a matched case-control study in two university hospitals caring for pregnant women in Yaoundé Cameroon; women with diagnosed EP (cases) and those with first trimester intrauterine pregnancy (IUP) as the controls. Th...

Acute urinary tract infection is a common clinical problem, especially during pregnancy due to urinary stasis. Superinfection of this urinary stasis in the intra-renal excretory ducts produces pyonephrosis, the occurrence of which during pregnancy has rarely been described in the literature. Herein, we report a case of pyonephrosis complicating pye...

Background: Adolescent pregnancies are characterized by high rate of maternal, foetal and neonatal morbi-mortality. Adherence to antenatal care still remains a major challenge amongst pregnant adolescents in a resource-limited setting. Objective: The aim of this study was to determine the rate of loss to follow up of adolescent pregnancies and desc...

Introduction L’impact des références sur la survenue des complications obstétricales n’est pas encore connu. Notre but était d’identifier les complications associées aux références obstétricales à Yaoundé. Méthodes Il s’agissait d’une étude transversale descriptive et analytique du 1er Février au 31 Juillet 2015 à l’Hôpital Gynéco-Obstétrique et P...

Objective: To identify nuchal cord risk factors. Methods: The present case-control study was carried out between December 2016 and April 2017 at two hospitals in Yaoundé, Cameroon. Singletons with a nuchal cord at delivery (case group) as well as the two neonates without a nuchal cord delivered immediately after each case (control group), all in...

Objective To evaluate the reproducibility of the 75 g oral glucose tolerance test and factors associated with non-reproducible results in Cameroonian pregnant women. ResultsTwenty-seven of the 84 participants (32.1%) who did the first oral glucose tolerance test were diagnosed with gestational diabetes mellitus. There was no difference between the...

Introduction Access to laparoscopy is low in Cameroon where customers' satisfaction has not been reported so far. We assessed patients' satisfaction with the process of care during laparoscopic surgery in a new tertiary hospital. Methods A questionnaire was addressed to consenting patients (guardians for patients under 18) with complete medical re...

Background and objectives Vaginal breech delivery (VBD) is known to be associated with more perinatal and maternal complications. Very few studies on the subject have been carried out in poor-resource settings. The aim of this study was to determine maternal and neonatal outcomes in carefully selected cases of VBD for singleton term pregnancies in...

Background: Breast cancer is today a global health problem. With 1,671,149 new cases diagnosed in 2012, it is the most common female cancer in the world and accounts for 11.9% of all cancers and it affects more people than prostate cancer. In 2008, The United States statistics showed that, for all cancer that affect women before 40 years, more than...

Background: Congenital uterine anomalies like bicornis or bicornuate uterus are relatively rare in sub-Saharan Africa. They are associated with an increased rate of spontaneous abortion, preterm delivery, and infertility. The occurrence of bicornis bicollis uterus with unilateral cervical atresia is exceptional and its management is controversial....

Background: Little evidence exists on the efficacy and safety of the different surgical techniques used in the treatment of postpartum haemorrhage (PPH). We aimed to compare uterus preserving surgery (UPS) versus hysterectomy for refractory PPH in terms of perioperative outcomes in a sub-Saharan African country with a known high maternal mortality...

Background: Malaria is still a major public health problem in sub-Saharan Africa. The aim was to determine the prevalence of malaria infection at the onset of labor and the resulting complications.Methods: We carried out a five-month cross-sectional study at the Yaoundé Gyneco-Obstetric and Pediatric Hospital. We used results from the rapid diagnos...

Background: Kaolin consumption is common in our sub-Saharan Africa. The objective of this study was to assess the effects of kaolin consumption on the outcome of surgery in women. Methods: It was a cohort study comparing the occurrence of complications during labor among 263 consecutively recruited women who underwent gynecologic or obstetric surge...

Background: Nuchal cord is a common occurrence at delivery and it is known to be associated with birth asphyxia and perinatal death. The objective of this study was to identify the predictive factors of perinatal death in the presence of nuchal cord. Methods: This was a case-control study carried out during the period from October 1st 2014 to April...

The partogram is an inexpensive tool which can provide a continuous pictorial overview of labour and is essential to monitor and manage labour. The success of its use requires that it is available in the first place and secondly that it is being put into use. In order to be successful, the partogram must be used in the continuous monitoring of labo...

Background: Adolescence is a period of life between 10 and 19 years, marked by a state of psychological imbalance and immaturity of organs. The occurrence of pregnancy at this age group can cause social, psychological or obstetric problems (prematurity, unsafe abortion, obstructed labor). The objective of this study was to identify the risk factors...

Objectives . We aimed to assess the variation of insulin sensitivity in relation to obesity in women living with PCOS in a sub-Sahara African setting. Methods . We studied body composition, insulin sensitivity, and resting energy expenditure in 14 PCOS patients (6 obese and 8 nonobese) compared to 10 matched nonobese non-PCOS subjects. Insulin sens...

Introduction: Breast cancer is the most common cancer and the first cause of cancer-related deaths among women in Cameroon. The aim of the study was to investigate its risk factors for breast cancer at two University Teaching Hospitals in Yaounde. Methodology: A case-control study was conducted for 5 months, from February 25th to July 25th 2015, at...

Résumé L’obésité est retrouvée chez 25 % des Camerounaises. Les données et complications associées à l’obésité en grossesse ne sont cependant pas connues dans notre milieu. Objectifs Notre étude avait pour but de décrire l’issue maternofœtale de la grossesse chez la femme obèse à l’hôpital gynéco-obstétrique et pédiatrique de Yaoundé au Cameroun...

Unlabelled: The gynecological examination is a key element in the diagnosis of the most genitourinary disorders. Improving how women experience the first gynecological examination (FGE) should have a significant impact on their perception of this examination and on their general feeling about it afterwards. Objective: The aim of our study was to...

Objective: To identify the risk factors for emergency cesarean deliveries and assess the effects of the emergency situation on maternal and fetal prognosis. Methods: This retrospective cohort study compared emergency and elective cesarean deliveries performed at the Yaoundé Women's and Children's Hospital in Cameroon, analyzing socioeconomic var...

Introduction L’obésité accroit le risque d’infertilité car l’hyperinsulinisme associé cause une hyperandrogenémie interférant avec la folliculogénèse et la secrétion des gonadotrophines centrales. Le syndrome des ovaires polykystiques (SOPK), plus souvent retrouvé chez des patientes d’IMC de 25 kg/m², constitue la principale cause d’infertilité. L’...

Unlabelled: Excessive weight gain (EWG) during pregnancy can cause maternal and fetal complications. It has not yet been studied in our social environment, however. Objectives: Our study aimed to describe maternal and fetal outcome in women gaining excessive weight during pregnancy in Cameroon. Methodology: This cross-sectional descriptive stu...

This is a retrospective analysis of eight years of gynaecological laparoscopic surgery in a resource-limited setting. All gynaecological patients managed by laparoscopy at the Yaoundé Gynaeco-Obstetric and Paediatric Hospital from 1 January 2004 to 30 November 2011 were included. Amongst the 9194 gynaecological surgeries performed during the study...

Objective To analyze the outcome of repeat repair of vesico-vaginal fistula following a failure. Methods This was a cross-sectional analytic study in two different obstetric fistula surgery units at the Regional Hospital of Maroua-Cameroon and the University Teaching Hospital of Yaoundé-Cameroon. The study period covered from January 2005 to Decem...

Abstract Objective Our aim was to assess the effects of sexual activity during pregnancy on the prognosis of labor. Methods It was a prospective cohort study of labor comparing 72 women declaring unprotected vaginal sexual intercourse after 37 weeks of pregnancy consecutively recruited to 72 women claiming no sexual contact after 37 weeks of pregna...

Women older than 40 years have been termed "advanced maternal age" and considered to be at risk of adverse pregnancy outcome. This study aimed to examine the obstetrical outcomes among primiparous and multiparous African advanced maternal age women. We conducted a retrospective cohort study study at two teaching hospitals at Yaounde, Cameroon. From...

As far as we know, the accuracy of clinical judgment in diagnosing uterine cervical polyps has not been assessed in sub-Saharan Africa. Our objective was to discover the positive predictive value (PPV) of clinical judgment in the diagnosis of cervical polyps. This is a retrospective descriptive study of 192 patients, carried out by the Departments...

The objective of this study was to describe the extent of sexual activity in adolescent school girls. This was a cross-sectional study with prolective collection of data carried out at Lycée General Leclerc, Yaounde (Cameroon), from October 1 to November 30, 2011. Heterosexual coitus was considered as sexual activity. A pretested self-administered...

Aim: The objective was to describe the clinical and therapeutic aspects of breast cancer at the Yaounde Gynaeco-Obstetric and Pediatric Hospital, which is a referral centre for gynecological malignancies. Methods: It was a retrospective descriptive study over a period of four years, from June 1st 2003 to May 31st 2007. Results: Sixty five pati...

Breech presentation remains a hazard for the mother and her fetus. To reduce its incidence at delivery, postural techniques have been used, among which the knee-chest position. The objective of this study was to assess the effectiveness of this position on cephalic version of breech presentation. It was a prospective randomized study in a group of...