Dk Vns Malleswara

Dk Vns Malleswara
Sri Sathya Sai Institute of Higher Learning · Department of Biosciences

Doctor of Philosophy

About

8
Publications
2,285
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17
Citations
Introduction
Additional affiliations
June 2014 - April 2019
Sri Sathya Sai Institute of Higher Learning
Position
  • Professor (Assistant)

Publications

Publications (8)
Article
Full-text available
There is a growing demand for new diabetes drugs with fewer side effects to replace current medications known for their adverse effects. Inhibition of α-glucosidase responsible for postprandial hyperglycemia among diabetes patients is a promising strategy for managing the disease. This study aims to explore and identify novel bioactive metabolites...
Article
Full-text available
Background Understanding how ectotherms manage energy in response to temperature is crucial for predicting their responses to climate change. However, the complex interplay between developmental and adult thermal conditions on total energy stores remains poorly understood. Here, we present the first comprehensive quantification of this relationship...
Article
Full-text available
In ectotherms, body temperature is a crucial determinant of performance and fitness, as captured by thermal performance curves (TPCs). Since survival in variable environments is often facilitated by phenotypic plasticity, to reliably assess an organism’s ability to cope with thermal changes, it is necessary to characterize not only TPCs but also th...
Article
Full-text available
Diabetes-associated postprandial hyperglycemia is a major risk factor in cardiovascular disease. Since enzyme α-glucosidase is primarily responsible for glucose release during digestion, inhibiting it mitigates post-meal spike in blood glucose level. Metabolites from endophytic fungi could be potential natural inhibitors of this enzyme. Endophytic...
Chapter
Endophytic fungi are a unique group of microfungi that inhabit all the plants. Their potential for being good sources of novel bioactive molecules (secondary metabolites) is yet to be fully tapped. These novel bioactive molecules have the potential to replace synthetic drugs in a significant way in the treatment of several diseases. The stumbling b...
Article
Full-text available
The physiology of Pila globosa (Indian apple snail) under heat shock was analyzed by measuring activities of two anti-oxidative enzymes and one oxidative enzyme in selected tissues. The temperature set points for the experiments were based on the climatic variations the snail gets exposed during an annual period in the specific geographical region....
Article
Full-text available
Fresh water snails are widely distributed in terrestrial habitats, typically in moist environments that fa- cilitate animals for gaseous exchange and reduce desiccation. Such habitats do undergo frequent seasonal changes that impact animal life. To survive dry, hot seasons and scarcity of food conditions, snails innately enter a dormant state by cl...
Article
Full-text available
Factors leading to aestivation (summer sleep) invariably display features of stress and hence it is of interest to understand and elucidate the role of heat shock proteins (HSP`s) during cellular stress response in an aestivating amphibious Indian apple snail Pila globosa. Expression of Inducible HSP40 was documented in the hepatopancreatic tissue...

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