Diogo Pais

Diogo Pais
Universidade NOVA de Lisboa | NOVA · Department of Anatomy

MD MSc PhD Agg

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150
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Publications

Publications (150)
Article
The attitudes of medical students towards the clinical importance of neuroanatomy have been little studied. Because it has been reported that medical students find neuroanatomy difficult and can have „neurophobia‟, here we test the hypothesis that early-stage medical students across Europe have a low regard for neuroanatomy‟s clinical relevance. Th...
Article
Background X ray Fluorescence has been essayed as a suitable technique for the elemental quantification of trace element in human tissues, namely comparison of normal and cancerous tissue. However, accurate results depend on a robust quantification approach, namely correct evaluation of the samples’ dark matrix. Methods In order to determine the m...
Poster
Several cadaveric fixation methods are used to keep human bodies preserved in the best possible way. According Healy et al (1), the formaldehyde is the oldest and most effective and still the most widely used method of embalming, which allow the preservation of macroscopic and microscopic features. However, the International Agency for Research on...
Article
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Ethical issues that arise during the care of a pregnant woman with cancer are challenging to physicians, policymakers, lawyers, and the bioethics community. The main purpose of this scoping review is to summarize existing literature regarding the bioethical dilemmas when a conflict arises in the maternal-fetus dyad, like the one related to cancer a...
Article
Trace elements are present in minute amounts in the human body but contribute to its proper functioning, by participating in several biological processes. Imbalance of the concentrations of these elements can lead to the development of pathologies, including cancer. As such, the determination of trace element content in tumour tissues and its compa...
Article
During the course of our regular tutorial classes of Anatomy for undergraduates of the Nova Medical School of Lisbon, one of the students brought to our consideration the finding of a peculiar variation of the skull base foramina, in which she recognized duplication of the left foramen ovale. To the left, the medial foramen is 0.3 cm wide, and the...
Article
Whenever we present the clinical interest to undergraduate students, we verify immediate growth in enthusiasm and commitment for the study of medical subjects, and for anatomy in particular, thus permitting gradual introduction of more complex, modern clinical knowledge. In the particular case of the knee joint, we offer our undergraduate students...
Data
ENLARGED EMISSARY SPHENOIDAL FORAMEN? OR DUPLICATION OF FORAMEN OVALE? UNUSUAL ANATOMICAL FINDINGS ON HUMAN SKULL BASE, WITH CLINICAL IMPLICATIONS. Bettencourt Pires M.; Piagkou M; Silva-Junior EX; Natsis K; Sousa-Junior JR; Casal D; Pais D. [and the student Rodrigues Póvoa AR]. During our regular tutorial classes of Anatomy for undergraduates at...
Conference Paper
During our regular tutorial classes of Anatomy for undergraduates of the Nova Medical School of Lisbon, one of the students brought to our consideration the finding of a peculiar variation of the skull base foramina, in which she recognized duplication of the left foramen ovale. To the left, the medial foramen is 0.3 cm wide, and the lateral forame...
Conference Paper
Full-text available
Whenever we present the clinical interest to our undergraduate students, we soon verify an immediate growth in enthusiasm and commitment for the study of medical subjects, and for anatomy in particular, thus permitting the gradual introduction of more complex modern clinical knowledge. In the particular case of the anatomy of the knee joint, we off...
Article
Full-text available
Purpose The tympanic membrane (TM) belongs to the ear. Despite its place in the ear anatomy, can we give it also a different anatomic classification? The main objective is to clarify the nature of TM, tympanic bone and malleus to propose a new anatomic classification. Methods This cadaveric study was performed in two human heads and six fresh temp...
Article
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The main aim of this work was to study the usefulness of human β-defensins 2 (BD-2) and 3 (BD-3), which are part of the innate immune system, in the treatment of infected ischemic skin flaps. We investigated the effect of transducing rat ischemic skin flaps with lentiviral vectors encoding human BD-2, BD-3, or both BD-2 and BD-3, to increase flap s...
Article
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Background: Unconventional perfusion flaps offer multiple potential advantages compared with traditional flaps. Although there are numerous experimental articles on unconventional perfusion flaps, the multiple animal species involved, the myriad vascular constructions used, and the frequently conflicting data reported make synthesis of this inform...
Article
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Introdução: O objectivo do presente estudo é o relato de um caso de variação anatómica do nervo isquiático, por origem baixa e divisão alta bilateral. Material e Métodos: Foi dissecado um cadáver feminino de 66 anos, conservado pelas técnicas originais desenvolvidas no nosso departamento. Resultados: No trabalho regular de dissecção cadavérica da d...
Article
Full-text available
Due to its deep location, close to the elbow joint, the supinator muscle requires special dissection skills. This fact enhanced our interest for a more accurate knowledge of the anatomical relations of the muscle with the elbow joint and with the posterior branch of the radial nerve. There are many clinical consequences of these anatomic relations,...
Poster
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AGEING AND FERTILITY Bettencourt Pires, M.A. ; Esperança Pina J.A. ; Pais D. Dept of Surgery and Human Morphology, NOVA Medical School, Univ. Nova de Lisboa ABSTRACT The earliest signs of physical ageing can be found in the genital system, with consequent impairment of reproductive quality. In morphological terms, the landmarks of ageing are to b...
Article
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Introduction/Objectifs J. Dejerine (1849–1917) et A. Dejerine-Klumpke ont publié le tome 1 de leur atlas « Anatomie des centres nerveux » en 1895 [1]. Depuis lors, l’atlas est devenu une référence pour la morphologie du système nerveux (SN) pour l’enseignement, la recherche et la clinique. L’atlas n’est disponible qu’en Français. Le but de ce poste...
Poster
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We present a selection of images from a dissection class on the subject of the human knee. This corresponds to a successful teaching experience in which we presented the students some brief exposure of images from the technical arthroscopic approach to the human knee, then offering a human cadaveric specimen to explore through dissection. The under...
Data
Sempre que apresentamos o interesse clínico aos nossos alunos de pré-graduação, verificamos o imediato acréscimo do entusiasmo e maior empenho pelos estudos médicos e pela anatomia, em particular. O passo seguinte será a introdução gradual de conceitos clínicos mais especializados, de cada um dos assuntos que ensinamos nos cursos de pré-graduação e...
Conference Paper
Full-text available
O trabalho ilustra as técnicas originais de preservação cadavérica desenvolvidas no Departamento de Anatomia da NOVA Medical School de Lisboa. O sistema de embalsamamento cadavérico por bomba propulsora de perfusão arterial, monitorizado por programa informático específico, patenteado internacionalmente, permite preservação das características teci...
Conference Paper
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Profundamente localizado, em íntima relação com a articulação do cotovelo, o músculo supinador implica especial destreza na dissecção. O especial empenho nas esmeradas dissecções vem colmatar a escassez de trabalhos anatómicos sobre este músculo e suas relações com o cotovelo e o nervo perfurante. Comemoram-se 400 anos da primeira referência à pass...
Article
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The aim of this study was to evaluate in the Wistar rat the efficacy of various autologous nerve conduits with various forms of blood supply in reconstructing a 10-mm-long gap in the median nerve (MN) under conditions of local ischemia. A 10-mm-long median nerve defect was created in the right arm. A loose silicone tube was placed around the nerve...
Data
Infra-red thermography evaluation of the region of the forepays innervated by the median nerve 90 days postoperatively. NG, nerve graft; CNF, conventional nerve flap; ANVF, arterialized neurovenous flap; PNF, prefabricated nerve flap. D, day after the beginning of the experiment. Numeric variables are expressed as average ± standard deviation. (DOC...
Data
Walking track analysis results throughout the experiment. NG, nerve graft; CNF, conventional nerve flap; ANVF, arterialized neurovenous flap; PNF, prefabricated nerve flap. D, day after the beginning of the experiment. Numeric variables are expressed as average ± standard deviation. (DOCX)
Data
Evaluation of retrograde marking of the right median nerve proximally to the lesion site, of the right C7 dorsal ganglion and of the right ventral horn of the spinal cord at the C7 level. NG, nerve graft; CNF, conventional nerve flap; ANVF, arterialized neurovenous flap; PNF, prefabricated nerve flap. N/A, non-applicable. All parameters are express...
Data
Summary of the correlations found between functional motor variables and neurophysiological and histomorphometric variables. CMAP, compound muscle action potentials; FCR, flexor carpi radialis; AUC, area under the curve; MN, median nerve; DRG, dorsal root ganglion. (DOCX)
Data
Summary of the correlations found between nociception assessment 90 days after surgery and functional motor, neurophysiological and histomorphometric variables. D90, ninety days after surgery; CMAP, compound muscle action potentials; MN, median nerve; DRG, dorsal root ganglion. (DOCX)
Data
Histomorphometric evaluation of the right median nerve distally to the repair zone and of the vascular density in the middle portion of the reconstructed nerve defect in the different experimental groups. NG, nerve graft; CNF, conventional nerve flap; ANVF, arterialized neurovenous flap; PNF, prefabricated nerve flap. N/A, non-applicable. All param...
Article
Full-text available
There is evidence that nerve flaps are superior to nerve grafts for bridging long nerve defects. Moreover, arterialized neurovenous flaps (ANVFs) have multiple potential advantages over traditional nerve flaps in this context. This paper describes a case of reconstruction of a long defect of the ulnar artery and nerve with an arterialized neuroveno...
Article
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Background Many fundamental questions regarding the blood supply to the integument of the rat remain to be clarified, namely the degree of homology between rat and humans. The aim of this work was to characterize in detail the macro and microvascular blood supply to the integument covering the ventrolateral aspect of the abdominal wall of the rat....
Article
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Background Although numerous experimental models of arterialized venous flaps (AVFs) have been proposed, no single model has gained widespread acceptance. The main aim of this work was to evaluate the survival area of AVFs produced with different vascular constructs in the abdomen of the rat. Methods Fifty-three male rats were divided into 4 group...
Article
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Background Open injuries to the face involving the external carotid artery are uncommon. These injuries are normally associated with laceration of the facial nerve because this nerve is more superficial than the external carotid artery. Hence, external carotid artery lesions are usually associated with facial nerve dysfunction. We present an unusua...
Article
Medical and dental curricula, together with anatomical sciences courses, are increasingly having to change, mainly because there is a drive to being what is termed, without adequate definition, 'clinically relevant'. The concept of 'clinical anatomy' has accordingly been invented and it is expected that, at all times, the teaching of anatomy is dir...
Article
Full-text available
Many studies have been undertaken to assess the attitudes of medical students to the clinical importance of gross anatomy. However, much less is known about their attitudes towards the clinical importance of histology. Using Thurstone and Chave methods to assess attitudes, over 2,000 early stage medical students across Europe provided responses to...
Article
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http://revistas.rcaap.pt/anestesiologia/article/view/7323 Introdução: A recusa em receber derivados do sangue a que as Testemunhas de Jeová estão submetidas levanta problemas éticos e legais relativamente ao modo como proporcionar os melhores cuidados de saúde a estes pacientes. No presente artigo discutimos os princípios Bioéticos envolvidos bem...
Data
open the link: https://prezi.com/u0uekzmkqhs2/lisbon-dissection-room-june2013
Article
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Free tissue transfer has been increasingly used in clinical practice since the 1970s, allowing reconstruction of complex and otherwise untreatable defects resulting from tumor extirpation, trauma, infections, malformations or burns. Free flaps are particularly useful for reconstructing highly complex anatomical regions, like those of the head and n...
Article
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Background Although open injuries involving the brachial plexus are relatively uncommon, they can lead to permanent disability and even be life threatening if accompanied by vascular damage. We present a case report of a brachial plexus injury in which the urgency of the situation precluded the use of any ancillary diagnostic examinations and force...
Article
Background: Sacral nerve stimulation is a common treatment for various pelvic floor disorders. It consists of the percutaneous introduction of electrodes through the posterior sacral foramina for therapeutic stimulation of the target sacral spinal nerve. The aim of our study was to determine the surface anatomical landmarks of the sacrum to facili...
Article
Introduction With the publication of "To Err is Human: Building a Safer Health System" 1 and several other studies, such as the Harvard Medical Practice Study, the issues of patient safety (PS) and Adverse Events (AE) (which attracts more media attention) were brought into the limelight and subjected to public opinion. In spite of being the basis o...
Article
Background: Although unconventional perfusion flaps have been in clinical use since 1975, many surgeons are still deterred from using them, because of some reports of high necrosis rates. Methods: The authors performed a systematic review and meta-analysis of all articles written in English, French, German, Spanish, and Portuguese on the clinica...
Article
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Teaching time dedicated to anatomy education has been reduced at many medical schools around the world, including Nova Medical School in Lisbon, Portugal. In order to minimize the effects of this reduction, the authors introduced two optional, semester-long cadaveric dissection courses for the first two years of the medical school curriculum. These...
Article
The use of optional (elective) courses within the medical curriculum is increasingly being seen as a way of allowing students to pursue their studies according to their personal interests. For anatomy, particularly where the subject is being taught in an integrative curriculum and by means of a systemic approach, the development of elective regiona...
Article
Full-text available
Os bloqueios anestésicos tronculares do períneo feminino são opções terapêuticas importantes no trabalho de parto e na realização de várias intervenções invasivas perineais, permitindo a realização de procedimentos cirúrgicos sem necessidade de anestesia geral. Contudo o conhecimento da anatomia dos nervos que suprem esta região é disperso, muitas...
Article
Full-text available
Introdução: Contrariamente ao que muitas vezes é ensinado, no ensino médico pré-graduado, as peças ósseas e cartilagíneas do adulto apresentam inúmeras variações anatómicas. A variabilidade de estruturas consideradas constantes pode condicionar erros de diagnóstico e terapêuttica, se não fr tida em consideração. [...]
Conference Paper
Full-text available
Introdução: Ao contrário do que muitas vezes é ensinado no ensino médico pré-graduado, as peças ósseas e cartilagíneas do adulto apresentam inúmeras variações anatómicas. A variabilidade de estruturas consideradas constantes pode condicionar erros de diagnóstico e terapêutica, se não for tida em consideração. Métodos: Durante os trabalhos de dissec...
Conference Paper
Full-text available
50a Reunião Científica da SAP e 3a Reunião Científica da AAP, Braga, 30 Abril 2016. Bases anatómicas dos bloqueios anestésicos tronculares perineais femininos: uma revisão narrativa da literatura ilustrada com dissecção cadavérica. Raquel Lopes (1); Diogo Casal (2,4); Fátima Serrano(1,3); Maria Alexandre Bettencourt Pires (4); Diogo Pais (4); João...
Conference Paper
POSTGRADUATE TEACHING IN THE DEPARTMENT Of ANATOMY OF THE NOVA MEDICAL SCHOOL OF LISBON Goyri-O'Neill J.; Pais D. Department of Anatomy. NOVA Medical School of Lisbon. Portugal Maintaining the regular practice of cadaveric dissection has always been one of the main issues, since the foundation of the Anatomy Department of the Faculty of Medical Sc...
Article
Although there have been many studies reporting the attitudes of medical students to the clinical importance of gross anatomy, little is known about their opinions concerning the clinical importance of embryology. Using Thurstone and Chave methods to assess attitudes, nearly 1,600 medical students across Europe in the early stages of their training...
Article
Full-text available
strong>Introduction: Olfaction is frequently affected in chronic rhino-sinusitis with polyposis and has been recognised to have important impact on quality of life. Surgical resolution on cases of maximal medical therapy failure is an option to relieve symptoms, with debates as to how extensive surgery should be. A more radical approach will achiev...
Article
Full-text available
Introduction: Olfaction is frequently affected in chronic rhino-sinusitis with polyposis and has been recognised to have important impact on quality of life. Surgical resolution on cases of maximal medical therapy failure is an option to relieve symptoms, with debates as to how extensive surgery should be. A more radical approach will achieve bett...
Article
There is increasingly a call for clinical relevance in the teaching of biomedical sciences within all health care courses. However, this presupposes that there is a clear understanding of what can be considered core material within the curricula. To date, the anatomical sciences have been relatively poorly served by the development of core syllabus...
Article
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http://www.sociedadeanatomica.pt/site/upload/files/fich_99218405585_foma-editada--archives-of-anatomy.pdf
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http://www.sociedadeanatomica.pt/site/upload/files/fich_99218405585_foma-editada--archives-of-anatomy.pdf
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http://www.sociedadeanatomica.pt/site/upload/files/fich_99218405585_foma-editada--archives-of-anatomy.pdf
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http://www.sociedadeanatomica.pt/site/upload/files/fich_99218405585_foma-editada--archives-of-anatomy.pdf
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Online Edition of the Abstracts of Works presented at the 49th Scientific Meeting of the Portuguese Anatomical Society, May 23rd, 2015.http://www.sociedadeanatomica.pt/site/upload/files/fich_99218405585_foma-editada--archives-of-anatomy.pdf