Dinesh Babu Manikandan

Bharathidasan University | bdu · Department of Animal Science

Aporosa cardiosperma is a plant species majorly found in the Indian Western Ghats that belongs to the phyllanthaceae family with ethnobotanical importance. Using a Fourier Transform-Infrared Spectrometer (FT-IR) and Gas Chromatography-Mass Spectrometry (GC–MS) for evaluating leaf extracts of A. cardiosperma, significant functional groups and metabo...

The expanded emergence of drug‐resistant microbes remains a concern to the scientific community in developing effective therapeutics. Approach of green chemistry based nanomaterials fabrication is in high demand, due to biocompatibility, non‐toxic, and high surface area that adheres more biomolecules on surface. Green fabricated silver nanoparticle...

Aeromonas hydrophila, an opportunistic bacteria, causes several devastating diseases in humans and animals, particularly aquatic species. Antibiotics have been constrained by the rise of antibiotic resistance caused by drug overuse. Therefore, new strategies are required to prevent appropriate antibiotic inability from antibiotic-resistant strains....

In this study, a sustainable fabrication of hybrid silver-copper oxide nanocomposites (Ag-CuO NCs) was accomplished utilizing Ocimum americanum L. by one pot green chemistry method. The multifarious biological and environmental applications of the green fabricated Ag-CuO NCs were evaluated through their antibacterial, anticancer, dye degradation, a...

The present study investigated the dietary fishmeal replacement by marine red seaweed (Halymenia dilatata) meal (RSM) on growth performance, feed utilization, chemical body composition, hematological constituents, digestive, antioxidant, and metabolic enzymes in freshwater fish Labeo rohita (Rohu) fingerlings. The fish were fed with RSM-free contro...

Fish skin mucus secretion is an important strategy against pathogens since it contains several immune molecules that act as the first line of defence. To date, several studies have reported that the mucus composition and immune responses vary depending on the fish species, and consequently, the comparative studies on skin mucus may have beneficial...

The risk faced by the drug-resistant pathogens, research, and development for viable alternative medicine is gaining traction. This study aims to utilize agricultural waste beneficially, by investigating the methanol, ethanol, acetone, ethyl acetate, petroleum ether, and hexane extracts of black gram pods by gas chromatography-mass spectrometry (GC...

Nanotechnology is an expanded branch of current research that involves the production and customization of particle structures with typical sizes of less than 100nm for various uses. A large area of surface to volume ratio was related with minimum surface functionalization, resulting in nanostructured metal oxide nanoparticles with outstanding biom...

Groundnut shells (GNS) make up about 20% of the weight of a dried peanut pod, indicating a substantial amount of shell residue after groundnut processing. In primary screening, bioactive metabolites present in the various GNS extract solvents like methanol, ethanol, acetone, ethyl acetate, hexane and petroleum ether were analyzed. Further, in the q...

The epidermal mucus of fish performs diverse functions from prevention of mechanical abrasion to limit pathogen invasions. The current experiment was designed to extract skin mucus proteins of three freshwater fish, i.e. common carp (Cyprinus carpio), mrigal (Cirrhinus mrigala) and rohu (Labeo rohita) with organic solvent (methanol) and dissolve in...

Nanotechnology tends to be a swiftly growing field of research that actively influences and inhibits the growth of bacteria/cancer. Noble metal nanoparticles (NPs) such as silver, copper, and gold have been used to damage bacterial and cancer growth over recent years; however, the toxicity of higher NPs concentrations remains a major issue. The cop...

The teleost fish skin mucus acts as an important physical and biological barrier that prevents fish from the surrounding environment. Many studies reported the presence of various immunological molecules in fish skin mucus that involve in protection against invading microbes. In the present study, the skin mucus proteins of freshwater fish Cirrhinu...

The green synthesis of nanoparticles using plant extracts attracts considerable interest from researchers as an eco-friendly alternative approach to conventional physical and chemical approaches to avoid toxic chemicals for the development of modern nanotechnology resources. In this study, Syzygium cumini (Java plum) aqueous leaf extract was used a...

Fish skin mucus acts as an immunological barrier that prevents entry of pathogens. However, there are gaps in the knowledge of microbes inhabiting skin mucus constituents to invade the host and induce pathogenecity. Hence, in the present study, skin and skin mucus of three freshwater fishes Cyprinus carpio, Labeo rohita, Cirrhinus mrigala was analy...

The present study investigated the effects of Aquamin® mineral mixture (AQMM) and Agrimin® mineral mixture (AGMM) supplemented diets on growth and chemical composition of juvenile freshwater prawn Macrobrachium malcolmsonii (H. Milne-Edwards, 1844). Experimental diets containing 6 different AQMM levels (Trial 1: 0, 0.5, 1.0, 1.5, 2.0, and 2.5%) and...

The present study investigated the effects of Aquamin® mineral mixture (AQMM) and Agrimin® mineral mixture (AGMM) supplemented diets on growth and chemical composition of juvenile freshwater prawn Macrobrachium malcolmsonii (H. Milne-Edwards, 1844). Experimental diets containing 6 different AQMM levels (Trial 1: 0, 0.5, 1.0, 1.5, 2.0, and 2.5%) and...

Green fabrications of metallic nanoparticles are rapidly developing the research era, due to their broad spectrum of applications in the field of biomedical sciences. In the present study, the green fabrication of silver nanoparticles (AgNPs) has been demonstrated by a highly stable, biocompatible, and environmental friendly aqueous leaf extract of...

In this study, we emphasize a rapid and cost-effective biogenic approach for the synthesis of silver nanoparticles (AgNPs) using an aqueous extract of onion (Allium cepa L.) peel (brown skin) acting as a reducing and capping agent. The synthesized AgNPs were characterized by UV-visible spectroscopy, X-ray diffraction (XRD), Fourier transform infrar...

Zinc oxide nanoparticles (ZnO NPs) are gaining interest due to their multifunctional properties and desirable biological activities. The present study reports the formulation and characterization of ZnO NPs using an aqueous extract of dry onion peels (Allium cepa L) and further investigates their photocatalytic, in vitro antipathogenic activity and...

Recent studies on flavonoids forming complexes with macromolecules attract researchers due to their enhanced bioavailability as well as chemo-preventive efficacy. In this study, a flavonoid rutin (Ru) is non-covalently complexed with fucoidan (Fu) using the functional groups to obtain a therapeutic polymeric complex overcoming the limitations of bi...

In the quest for developing a biological-based nanomaterial for therapeutic applications, here we report a novel benign method of silver nanoparticles synthesized using the endophytic fungi Phomopsis liquidambaris strain SA1 (SAAgNPs). A viable method was developed to generate silver nanoparticles by reacting with silver nitrate and an extracellula...