Dimitris P Makris

Dimitris P Makris
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Dimitris verified their affiliation via an institutional email.
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Dimitris verified their affiliation via an institutional email.
  • PhD DIC
  • Professor (Associate) at University of Thessaly

About

225
Publications
111,154
Reads
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9,878
Citations
Introduction
Associate Professor, Department of Food Science & Nutrition, University of Thessaly; Head, Green Processes & Biorefinery Group
Current institution
University of Thessaly
Current position
  • Professor (Associate)
Additional affiliations
February 2019 - present
University of Thessaly
Position
  • Professor (Associate)
Description
  • Head, Green Processes & Biorefinery Group
April 2018 - January 2019
Technological Educational Institute of Thessaly
Position
  • Professor (Associate)
October 2008 - June 2009
T.E.I. of Crete
Position
  • Lecturer
Education
October 1997 - February 2001
Independent Researcher
Independent Researcher
Field of study
  • Food Chemistry

Publications

Publications (225)
Article
Full-text available
Citation: Roufas, K.; Chatzimitakos, T.; Athanasiadis, V.; Lalas, S.I.; Toulaki, A.; Makris, D.P. Polyphenolic, Anthocyanin, and Volatile Profile of Barrel-Aged Industrial Red Wines Made from Vitis vinifera Cv Maratheftiko. Beverages 2025, 11, 36. Abstract: Maratheftiko (Vitis vinifera sp.) is a prestigious grape variety native to Cyprus, but wines...
Article
Full-text available
Natural resources are currently overexploited to provide food supply for the ever-increasing world population, and because of the intensification of agricultural and food production, there is a growing rate of waste generation. This waste biomass is usually dumped into landfills, causing unprecedented damage to ecosystems. Nowadays, circular econom...
Article
Full-text available
Natural polyphenols may be very effective lipid antioxidants; however, the studies pertaining to specific commodities, such as refined olive kernel oil (OKO), are extremely limited, and thus there is a lack of relevant information. To provide coverage for this gap in the literature, this study was performed with the view of testing structurally rel...
Article
Full-text available
Olive leaves (OLLs) are an exceptional bioresource of natural polyphenols with proven antioxidant activity, yet the applicability of OLL extracts is constrained by the relatively high polarity of the major polyphenols, which occur as glycosides. To overcome this limitation, OLLs were subjected to both hydrothermal and ethanol organosolv treatments,...
Article
Full-text available
The grape variety Maratheftiko (V. vinifera sp.) is one of the most prestigious Cypriot varieties , yet Maratheftiko wines are rather poorly studied with regard to principal quality characteristics, such as the polyphenolic and aromatic profile. The current study was undertaken with the scope to investigate the effect of various common industrial p...
Article
Full-text available
The citrus processing industry is responsible for the generation of large volumes of waste side streams, represented principally by fruit peels. These tissues are exceptionally rich in polypheno-lic bioactive phytochemicals, and there has been a great industrial interest for their valorization. The examination presented herein targeted at developin...
Research
Full-text available
Agricultural practices, industrial manufacturing, and household consumption are just a few of the activities that contribute to the production of food waste biomass. Modern environmental theories, like that of the circular economy, are thought to provide the impulse behind the implementation of zero-waste policies. A huge percentage of this residua...
Article
Full-text available
Cotton stalks are residual biomass resulting from cotton bud harvesting, and they are composed primarily of lignocellulosic material. This material could be a source of functional polyphenols. To investigate this prospect, this study was undertaken with the view to examining whether an ethanol-based organosolv treatment could be suitable for produc...
Article
Full-text available
Citrus processing side-streams are largely represented by waste orange peels (WOP), and there are several techniques developed for polyphenol extraction from WOP; yet, there are a significant lack of methodologies based on non-conventional, green solvents. On this basis, this study was performed to assess a deep eutectic solvent (DES) synthesized w...
Article
Full-text available
The objective of this study was to determine the optimal conditions for the recovery of bioactive and antioxidant compounds in aqueous solutions of Cistus creticus leaves and then employ the optimal extract for the enrichment of yogurt samples. The optimal conditions were established by a response surface methodology and were determined to be a liq...
Article
Full-text available
The purpose of this investigation was (i) the development of a novel, green tertiary solvent system, composed of water, ethanol and glycerol, and (ii) the implementation of an organosolv treatment of red grape pomace (RGP) for the efficient production of polyphenol-containing extracts with enhanced antioxidant properties. The treatment developed wa...
Article
Full-text available
The current project aimed at examining the effect of the enrichment of commercial seed oils with waste orange peel (WOP) extracts on their polyphenolic profiles and resistance against oxidation. Polyphenol-containing WOP extracts were produced using a novel combination of ethanol and triacetin, and they were incorporated into seed oils (sunflower,...
Article
Full-text available
The current study aimed at developing an effective organosolv treatment, with the objective to obtain potato peel extracts highly enriched in polyphenols. To this end, two low-cost solvents were employed, 1- and 2-propanol, which are considered green, but they have been rather poorly studied compared to other conventional solvents, such as ethanol....
Article
Full-text available
The examination presented herein sought to establish a novel methodology for the efficient recovery of polyphenolic antioxidants from coffee processing residues, namely coffee silverskin (CSS). The process developed was an ethanol-based organosolv treatment, assisted by acid catalysis, using sulfuric acid or oxalic acid as the catalyst. The first a...
Article
Full-text available
Onion skins (OS) are a by-product of onion processing that causes both biological and environmental problems. Thus, OS could be used sustainably and as means of circular economy since they contain valuable bioactive compounds that can be used for the production of high-added-value products. This study aims to evaluate the potential antioxidant, ant...
Article
Full-text available
The present study examines, compares, and documents the environmental impact of five extraction techniques through Life Cycle Assessment (LCA). The material used was Moringa oleifera freeze-dried leaves and the assessment was based on their polyphenol content Three out of the five examined techniques are referred to in the literature as “green” tec...
Article
Full-text available
Oat bran (OB) may be regarded as food industry by-product, with a high perspective as a bioresource in the production of high-value polyphenolic substances. On this basis, the investigation presented herein aimed at (i) using 1- and 2-propanol organosolv treatment and studying the effect of an alkali (sodium hydroxide) catalyst on releasing bound p...
Article
Full-text available
Every day, more and more consumers choose to drink bottled water instead of tap water, since they believe that it is superior in quality. One of the criteria used by European consumers to choose bottled water is the geographical region of the spring. The flavor of the water is an additional factor that influences consumers' choices. As a result, de...
Article
Full-text available
The aim of this study was to evaluate the efficiency of successive extraction (using solvents of increasing polarity, namely hexane, ethyl acetate, acetone, ethanol, and water) of polyphenols from Cistus creticus L. The results were compared with the ones obtained from a single-solvent extraction (ethanol, water, and 50% ethanol: water). According...
Article
Full-text available
Background: Currently, the use of medicinal plants has increased. Artemisia species have been used in several applications, including medicinal use and uses in cosmetics, foods and beverages. Artemisia arborescens L. and Artemisia inculta are part of the Mediterranean diet in the form of aqueous infusions. Herein, we aimed to compare the secondary...
Article
The current examination dealt with the development of a methodology to produce quercetin, a multifunctional bio‐flavonoid, by designing task‐specific, highly acidic deep eutectic solvents, based on glycerol and natural organic acids. The purpose was to achieve a simultaneous hydrolysis of spiraeoside, the major quercetin glycoconjugate occurring in...
Article
Full-text available
To produce sufficient food for the expanding global population, natural resources are constantly being overused, and at the same time, wastes are being produced at an ever-increasing rate [...]
Article
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Apricot kernels are known to be rich in bioactive compounds such as polyphenols, which have applications in various fields such as cosmetology and the food industry. However, the extraction of these compounds has not been extensively studied. In this study, we aimed to extract oil from apricot kernels and investigate its composition and antioxidant...
Article
Full-text available
The vineyard of Cyprus is comprised largely of native Vitis vinifera varieties, which are rather underexploited with regard to wine production to date. Although empirical observations concur that several of these varieties may possess a high potential for the production of quality wines, analytical data pertaining to their polyphenolic composition...
Article
Full-text available
Apricots are one of the most important fruits in the Mediterranean region for both their nutritional and economic value. They are widely cultivated and consumed fresh or dried or are used in the food industry for the production of jams, juices, etc. In any case, the seeds they contain constitute waste. The kernels are very rich in bioactive compoun...
Article
Full-text available
The present study examines, compares, and documents the environmental impact of five extraction techniques through Life Cycle Assessment (LCA). The material used was Moringa oleifera freeze-dried leaves and the assessment was based on their polyphenol content Three out of the five examined techniques are referred to in the literature as “green” tec...
Article
Full-text available
This study had as a goal to carry out the drying of red grape pomace (RGP) using a 2 × 3 factorial design. The design of the experiment included combinations of time and temperature in order to achieve the lowest possible moisture levels and examine losses in precious polyphenols, but also the effect on the antioxidant properties of RGP extracts. D...
Article
Full-text available
In this study, an alternative debittering technique for olives, invented and patented by Prof. Vassilis Dourtoglou, was employed. Olive fruits (Olea europaea cv. Megaritiki) were stored under CO2 atmosphere immediately after harvest for a period of 15 days. After the treatment, a sensory evaluation between the olives stored under CO2 and those stor...
Article
Full-text available
Wheat bran (WB) is globally a major food industry waste, with a high prospect as a bioresource in the production of precious polyphenolic phytochemicals. In this framework, the current investigation had as objectives (i) to use ethanol organosolv treatment and study the effect of acid and alkali catalysts on releasing bound polyphenols, (ii) establ...
Article
Peppermint (Mentha × piperita L.) is a popular medicinal and aromatic plant, cultivated in several areas around the globe. Its functional and therapeutic potential has been largely attributed to its polyphenolic composition, yet rather a few investigations have delt with the preparation of polyphenol-enriched extracts from this plant. On this groun...
Article
Full-text available
Onion solid wastes (OSW) are a food side-stream with high polyphenolic load and distinguished polyphenolic profile. This study was conducted in order to explore a novel methodology of production of polyphenol-enriched extracts with antioxidant properties from OSW, using glycerol and green deep eutectic solvents (DES), composed of glycerol/citric ac...
Article
Full-text available
Waste orange peels (WOP) are a food processing residue rich in bioactive polyphenols. However, data on aqueous extraction processes for efficient polyphenol recovery are rather limited. The present study dealt with the optimization of WOP polyphenols, using a batch stirred-tank mode and water as solvent. After a preliminary single-factor examinatio...
Article
Full-text available
The interest in extracting bioactive compounds from food processing waste is growing unabated. Apricots are widely consumed worldwide, and many tons of waste are produced annually. Therefore, apricot pulp waste (APW) may serve as a rich source of bioactive compounds. In the present study, we investigated the extraction of antioxidant polyphenols an...
Article
Full-text available
To date, many studies have been published, aiming to extract bioactive compounds from plants. Lately, research focuses on maximizing the extraction yield, using environmentally friendly techniques and solvents. In this study, the extraction of polyphenolic compounds from Cistus creticus is discussed. Extraction of the compounds has been carried out...
Article
Full-text available
In this study, the use of pulsed electric field (PEF) for the extraction of polyphenols from mature Elaeagnus pungens ‘Limelight’ leaves is discussed. Optimization of the main parameters that affect the extraction process was carried out. More specifically, the composition of the solvent (ethanol, water, and mixtures of the two at a 25% v/v step gr...
Article
Rhodosporidium toruloides NRRL Y-27012 grown in glycerol, produced yeast biomass and secondary metabolites as lipids (L) and intra-cellular polysaccharides (IPS) in trials under nitrogen limitation (initial C/N molar ratios ≈50, ≈100, ≈160 and ≈240). Initial glycerol (Glol0) concentration for all experiments was ≈90 g/L. The yeast demonstrated very...
Article
Full-text available
This study explored the use of β-cyclodextrin (β-CD) as an additive to improve the aqueous extraction of antioxidant polyphenols from peppermint (Mentha χ piperita). For this purpose, an initial single-factor screening was performed to test the effect of β-CD concentration on the yield of polyphenol extraction. In the following step, the extraction...
Article
Full-text available
Extraction of polyphenolic compounds from lemon peels using deep eutectic solvents (DES) was investigated. A choline chloride-based DES paired with glycerol was used as the extraction solvent, alternative to conventional ones. Response surface methodology (RSM) was employed to optimize the extraction parameters, namely, the water concentration (CW)...
Research
Full-text available
Agricultural practices, industrial manufacturing, and household consumption are just a few of the activities that contribute to the production of food waste biomass. Modern environmental theories, like the circular economy, are thought to be the impulse behind the implementation of zero-waste policies. A huge percentage of this residual biomass has...
Article
Full-text available
The valorization of red grape pomace is significant as grape is one of the most cultivated fruits worldwide and generated by-product quantities are enormous. For this purpose, numerous encapsulation techniques have been developed. However, the studies on microemulsions composed with deep eutectic solvent extracts are very limited. In this study, re...
Article
Full-text available
In the framework of introducing green strategies for food processing, the industrial orientation has shifted towards the replacement of conventional petroleum-based solvents with alternative eco-friendly ones. On this basis, the objective of this study was to synthesize a novel, tertiary, food-grade deep eutectic solvent, composed of glycerol, citr...
Article
Full-text available
This study was focused on the simultaneous organosolv treatment/extraction of waste orange peels (WOP) for the effective recovery of polyphenolic antioxidants. The treatments were performed with aqueous glycerol mixtures, which were acidified either with citric acid or hydrochloric acid (HCl). Process optimization was carried out using response sur...
Article
Full-text available
Polyphenols are an important class of compounds, due to their excellent antioxidant properties. Lately, much effort has been placed into developing new extraction techniques and optimizing them, so that polyphenols can be retrieved more efficiently from the plant materials. One of the most recent advances in extraction techniques is pulsed electric...
Article
Full-text available
Sweet potatoes have multiple uses as food, feed, and in industrial production. They are characterized by their need for high temperatures for optimal development. This study aimed to analyze the quantitative and qualitative aspects of growing sweet potato cultivars in southwest Romania using mulching and non-mulching systems. The effects of mulchin...
Article
Full-text available
Olive leaves (OLL) are an agri-food waste that may be regarded as a bioresource rich in bioactive polyphenolic metabolites. In this examination, simultaneous organosolv treatment/extraction of OLL polyphenols at elevated temperatures (>110 �C) has been optimized using glycerol, but also two glycerol-based deep eutectic solvents (DES). The assessmen...
Article
Full-text available
In the current study, Hibiscus sabdariffa has been extracted by microwave-assisted extraction (MAEX). Citric acid-based deep eutectic solvents (DES) have been specially designed, where a hydrogen bond donor (HBD) (glycerol and ethylene glycol) and a hydrogen bond acceptor (HBA) (citric acid) with a certain molar ratio (1/4) were used. After the bes...
Article
Full-text available
The extraction of phenolic compounds from olive leaves was optimized using three glycerol-based deep eutectic solvents (DESs) with lysine, proline, and arginine. A three-level Box–Behnken design was used to examine the influence of the liquid/solid ratio, concentration of DESs, and extraction temperature on the yield of the extraction process. A se...
Article
Full-text available
Fοllow up with our previous study on the extraction of saffron processing waste polyphenols using deep eutectic solvents, the objective of this examination was a comparative evaluation of pressurized liquid extraction (PLE), stirred-tank extraction (STE) and stirred-tank extraction with ultrasonication pretreatment (STE/UP) with respect to the reco...
Article
Full-text available
This investigation was carried out with the scope to examine three commonly used cyclodextrins (CDs), β-cyclodextrin (β-CD), methyl β-cyclodextrin (m-β-CD) and 2-hydroxypropyl β-cyclodextrin (HP-β-CD) as green co-solvents for the effective extraction of polyphenols and pigment from onion solid wastes (OSW). Efficiency appraisal was based on the “ex...
Poster
Full-text available
The aim of this study was to reach the optimal conditions for whey proteins hydrolysis using the digestive enzymes, either separately or combined in order to generate peptides with higher antioxidant activity. A full factorial design was employed for the single enzymatic hydrolysis in order to evaluate the effect of two independent factors on the p...
Presentation
Full-text available
Abstract The hydrolysis of bovine whey proteins was optimized using chymotrypsin, trypsin, and pepsin. The aim of this study was to reach the optimal conditions for whey proteins hydrolysis using the digestive enzymes, either separately or combined in order to generate peptides with higher antioxidant activity. The optimum conditions were applied o...
Article
Full-text available
Olive leaves (OLL) are reported as a source of valuable antioxidants and as an agricultural by-product/waste. Thus, a twofold objective with multi-level cost and environmental benefits arises for a “green” standalone extraction technology. This study evaluates the OLL waste valorization through maximizing OLL extracts polyphenol concentration utili...
Cover Page
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Our paper was selected to be the cover page of the BEVERAGES forthcoming issue.
Article
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The current study evaluates the Pulsed Electric Field (PEF) technique for the extraction of polyphenols from the plants Rosa canina, Calendulaofficinalis and Castanea sativa. These plants are traditionally used both for the preparation of therapeutic decoctions and the aromatization of beverages (alcoholic or not). Pulses of 10 μs duration were use...
Article
Full-text available
In this examination, two glycerol-based deep eutectic solvents (DESs) were tested for their efficiency in the recovery of antioxidant polyphenols and anthocyanin pigments from red grape pomace (RGP). The two DESs synthesized had sodium acetate and sodium benzoate as hydrogen bond acceptors, to test the role of the hydrogen bond acceptor polarity on...
Article
Full-text available
The present study aimed to evaluate the pulsed electric field (PEF)-assisted extraction of phytochemicals from Salvia officinalis L. leaves. The study parameters included a PEF pulse duration of 10 or 100 μs for 30 min, using different “green” extraction solvents: pure ethanol, pure water, and their mixtures at 25, 50, and 75% v/v concentrations. T...
Article
Full-text available
Winemaking is a process that generates a large volume of solid waste biomass, which is currently under extensive investigation as a bioresource of precious polyphenolic compounds. These substances are retrieved from vinification side streams principally by deploying solid-liquid extraction methods. In this frame, the present investigation had as ob...
Article
Full-text available
This investigation had as objective to study the effective recovery of olive leaf (OLL) polyphenols using a blend of an L-lactic acid/ammonium acetate deep eutectic solvent (DES) with β-cyclodextrin (β-CD). Following an initial DES screening, the extraction process was optimised with response surface methodology by implementing Box-Behnken design....
Article
Medicinal and aromatic plants (MAPs) have always been a source of a vast variety of secondary metabolites with high biological potency. There is to-date an enormous ongoing research on the development of sophisticated methodologies for the production of bioactive MAP extracts, which may be applied in a spectrum of products, such as foods, pharmaceu...
Article
Full-text available
The aim of the present study was to evaluate the physical and antioxidant properties of microemulsions containing Moringa oleifera leaf extract (MLE) produced by the means of a deep eutectic solvent. Selected microemulsions containing MLE were incorporated in chocolate products to enrich them. Their color properties including CIE L*, a*, b* paramet...
Article
Full-text available
Olive leaves (OLL), an agricultural waste by-product, are considered a significant biore-source of polyphenols, known as bioactive compounds. This study evaluates the pulsed electric field (PEF) technique for the extraction of polyphenols from OLL. The study parameters included a series of "green" solvents (ethanol, water as well as mixtures of the...
Article
Full-text available
The aim of the present study was to evaluate the physical and antioxidant properties of chocolate alginate beads containing Moringa oleifera leaf extract (MLE) produced with ecofriendly solvent extraction technology (Deep Eutectic Solvents). The concentration of MLE incorporated was 0, 2, 4, and 6% w/w, and hardening time for ionotropic gelation wi...
Article
Full-text available
Pomegranate peel is a byproduct of pomegranate juice production, and is rich in polyphenol compounds. The objective of this study was to investigate the incorporation of pomegranate peel extract in chitosan films. Green deep eutectic solvents (DESs) were used as extraction solvents. Choline chloride (ChCl) and glycerol (Gly) were used as the hydrog...
Article
Full-text available
This study exploited the application of pulsed electric field (PEF) on the recovery of polyphenols from aerial parts of Sideritis scardica, tepals of Crocus sativus, and fruits of Vitis vinifera. Short pulses of 10 μs in a period of 1 ms were applied to the plant material, while different electric field intensities, 1.2 to 2.0 kV/cm were tested to...
Article
Full-text available
Quercetin (Qt) is a natural flavonoid of high biological significance, and it occurs in a wide variety of plant foods. Although its oxidation by various means has been extensively studied, its behavior with regard to thermal treatments remains a challenge. The study described herein aimed at investigating Qt thermal decomposition, by proposing an e...
Chapter
Food-processing by-products’ exploitation includes the recovery of fine chemicals and production of precious metabolites, such as natural antioxidants, enzymes, starch, pigments, etc., which are value-added products of high significance to the pharmaceutical, cosmetics, and food industries. Contemporary biocatalysis is based upon new tools and meth...
Article
Full-text available
The acknowledgement that uncontrolled and excessive use of fossil resources has become a prime concern with regard to environmental deterioration, has shifted the orientation of economies towards the implementation of sustainable routes of production, through the valorization of biomass. Green chemistry plays a key role in this regard, defining the...
Article
Full-text available
In a previous study, it was demonstrated that a novel deep eutectic solvent (DES), composed of lactic acid and sodium citrate dibasic at a molar ratio of 15:1 (LA-SCDB15), was a high-performing system with regard to polyphenol extraction from the medicinal plant Salvia fruticosa Mill. (Greek or Cretan sage). However, an issue of particular importan...
Article
Full-text available
There has been, to-date, a large number of studies pertaining to the exploitation of plant resources (herbs, botanicals, processing by-products) for the production of extracts enriched with bioactive substances [...]
Article
Full-text available
The aim of this study was the examination of the effect of ultrasonication pretreatment and thermal treatment of soft wheat bran (SWB) with a novel acidic, tertiary deep eutectic solvent, composed of glycerol/citric acid/glycine, on the polyphenol extraction yield and antioxidant activity. This was achieved by sequentially deploying ultrasonication...
Article
Polyphenols are commonly retrieved from plant material with solid-liquid extraction, the optimization of which requires fundamental laboratory-scale investigation, to clearly identify variables and variable levels crucial to the process. When performing scaling-up, the process result should be the anticipated one, irrespective of the scale adopted....
Article
Full-text available
There is, to-date, an expanding interest concerning the use of cyclodextrins as green food-grade co-solvents in the aqueous extraction of polyphenols, however, data regarding polyphenol extraction from waste orange peels (WOP) are lacking. On this ground, hydroxypropyl β-cyclodextrin (HP-β-CD), a highly water-soluble cyclodextrin, was used to devel...
Article
Full-text available
A series of citrate salts were tested as hydrogen bond acceptors to synthesize deep eutectic solvents (DES) based on lactic acid and glycerol, used as hydrogen bond donors. The DES produced were then screened to identify the highest performing system for the effective extraction of polyphenolic phytochemicals from the medicinal plant Salvia frutico...
Article
Full-text available
Salvia fruticosa Miller, also known as Cretan or Greek sage, is a medicinal plant with significant biological properties, which are largely ascribed to its polyphenolic composition, but there is to-date a scarcity of green and sustainable processes for efficient polyphenol extraction from this plant. The objective of this study was the implementati...
Article
Full-text available
Potato peels (PP) are a major agri-food side-stream originating from potato processing, but to date, their green valorization as a bioresource of antioxidant polyphenols is limited to extraction processes involving mainly water/ethanol-based solvents, whereas other eco-friendly methodologies are scarce. This study aimed at developing a simple, stra...
Article
Full-text available
S. fruticosa, collectively known as Cretan sage, is a medicinal plant to which a number of bioactivities have been attributed. In spite of its importance in nutrition and pharmacy, reports on the extraction of major polyphenols using sustainable processes are particularly limited. In this study, three common cyclodextrins, namely, methyl β-cyclodex...
Research Proposal
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Message from the Guest Editor There is to-date a large number of studies pertaining to the exploitation of plant resources (herbs, botanicals, processing by-products) for the production of extracts enriched in bioactive substances. The interest has been focused on the development of efficient and cost-effective downstream processes, which aim at pr...
Article
Full-text available
Olive leaves (OLL) are considered to be a highly appreciated bioresource of bioactive polyphenolic phytochemicals, embracing several different structures. However, extraction processes based on deep eutectic solvents (DES) are very limited despite the wide range of techniques developed for the efficient recovery of polyphenols. This study had as ob...
Article
Full-text available
Sambucus nigra flowers, known as elderberry flowers (EBF), are a plant tissue rich in polyphenolic phytochemicals with important bioactivities. However, there are few studies dealing with the production of polyphenol-containing EBF extracts. The objective of the investigation presented herein was the development of a high-performance green extracti...
Article
Full-text available
Moringa oleifera L. leaves are a plant tissue particularly rich in polyphenolic phytochemicals with significant bioactivities, and there has been significant recent interest for the production of extracts enriched in these substances. The current investigation is aimed at establishing a green extraction process, using a novel eco-friendly natural d...
Article
Full-text available
As the world’s population is rapidly expanding, environmental aggravation and bioresource depletion are becoming challenges of paramount importance [...]
Article
Full-text available
The current investigation was undertaken to examine saffron processing waste (SPW) as a bioresource, which could be valorized to produce extracts rich in antioxidant polyphenols, using a green, natural deep eutectic solvent (DES). Initially, there was an appraisal of the molar ratio of hydrogen bond donor/hydrogen bond acceptor in order to come up...
Article
Full-text available
The objective of the study presented herein was the optimisation of onion solid waste (OSW) polyphenol extraction, using sodium propionate-based deep eutectic solvents (DESs) and process variables optimised through response surface methodology. Initial screening of several novel DESs composed of either L-lactic acid or glycerol as hydrogen bond don...
Article
Full-text available
The investigation presented herein had as its scope the development of an integrated process for the efficient extraction of polyphenols from hop. For this purpose, a novel, natural deep eutectic solvent (DES) was synthesised, composed of glycerol and L-alanine, and the process was optimised by deploying a response surface methodology based on a Bo...
Article
Full-text available
In this study, peach pomace (PP) moisture reduction using conventional oven-drying was investigated by implementing the Box-Behnken experimental design, considering two major process variables, time-t and temperature-T. The purpose was the optimisation of the process to obtain PP extracts as rich as possible in total carotenoids (TCn). It was shown...
Article
Full-text available
Production of added products from industrial byproducts is a challenge for the current natural product industry and the extraction field more generally. Therefore, the aim of this study is to valorize the selected Mediterranean crops that can be applied as antioxidants, natural chelating agents, or even as biosolvents or biofuels after special trea...
Poster
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1st International Conference on Analytical and Bioanalytical Chemistry, Antalya Turkey, 27-30 March, 2019
Article
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This study aimed at investigating the effect of L-cysteine on the Cu 2þ-induced oxidation of quercetin, within a pH range varying from 6.7 to 8.3 and temperatures varying from 53 to 87 C. Initial examinations showed that quercetin degradation obeyed apparent first-order kinetics and it was significantly temperature-dependent. Modeling of the effect...
Article
Full-text available
A number of biological activities have been attributed to polyphenolic substances occurring in the leaves of the olive tree (O. europaea), an olive oil industry waste material, and for this reason several extraction processes have been developed for the efficient recovery of these phytochemicals. The study presented herein describes for the first t...
Article
Full-text available
Polyphenol-containing extracts from olive (Olea europaea) leaves (OLL) were obtained using a glycerol-based deep eutectic solvent (DES) and a combination of DES with methyl β-cyclodextrin (m-β-CD). The extracts were stored at various temperatures for a period of 20 days and the reducing power (PR) was monitored to trace changes in the antioxidant p...
Article
Full-text available
This study aimed at investigating the effect of l-ascorbic acid on the Cu²⁺-induced oxidation of quercetin, within a pH range from 6.7 to 8.3 and temperatures varying from 53 to 87 °C. Initial examinations showed that quercetin degradation obeyed apparent first-order kinetics and it was significantly affected by temperature. Modelling of the effect...
Article
Full-text available
Polyphenol extracts from Moringa oleifera leaves (MoL) were obtained with a glycerol-based low-transition temperature mixture (LTTM) and a combination of LTTM with 2-hydroxypropyl β-cyclodextrin (HP-β-CD). The extracts were maintained at 4, 22 and 50 °C for 18 days and the antiradical activity (A AR) was recorded to detect modifications in the anti...
Article
Novel low-transition temperature mixtures (LTTMs), composed of glycerol and sodium acetate, sodium propionate, and sodium butyrate, were synthesized with the aim to investigate the organic anion chain length effect on the performance of polyphenol extraction from the medicinal plant Origanum dictamnus. The LTTMs used as hydrogen bond donor:hydrogen...
Article
Full-text available
A novel deep eutectic solvent (DES) with optimised composition was used to evaluate the effect of methyl β-cyclodextrin (CD) on the efficiency of polyphenol extraction from Olea europaea leaves (OLLs). The process developed was based on a 2³ full-factorial design and response surface methodology to assess the simultaneous effect of CD concentration...
Article
Full-text available
The valorization of onion (Allium cepa) solid wastes, a 450,000 tonnes/year waste in Europe, by a green extraction method is presented. Polyphenols of onion solid wastes were extracted using eco‐friendly solvents, such as water and glycerol. The 2‐hydroxypropyl‐β‐cyclodextrin was also used as a co‐solvent for the augmentation of the extraction yiel...
Article
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The valorization of solid waste hemp (Cannabis sativa L.) by a non-conventional method is presented in this article. Hemp polyphenols were extracted using aqueous solutions of 2-hydroxypropyl-β-cyclodextrin as an eco-friendly extraction solvent. Cyclodextrins (CD’s) are known to enhance the extraction of polyphenols in water by forming water solubl...
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A novel LTTM composed of glycerol and sodium acetate was used to assess the effect of 2-hydroxypropyl β-cyclodextrin (CD) on the effectiveness of polyphenol extraction from M. oleifera leaves (MoL). The extraction process was based on a 2³-full factorial design and response surface methodology, to evaluate simultaneously the effect of CD concentrat...

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