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Current institution
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September 2018 - June 2022
Publications
Publications (35)
Bryophytes, which include about 24,000 taxa and consist of mosses (Bryopsida), liverworts (Hepaticopsida), and hornworts (Anthocerotopsida), are the largest group of secondary terrestrial plants after angiosperms. Indigenous communities globally use bryophytes for various medicinal purposes, including antimicrobial, antipyretic, dermatological, hep...
The Salvia genus, commonly referred to as “sage”, represents the largest genus within the family Lamiaceae. Approximately 1,000 species of the Salvia genus are known to grow naturally, primarily in southern Europe but also in other regions worldwide. A significant proportion of the species are utilized in traditional medicine. In vitro and in vivo...
Objective: This study aims to determine the chemical composition of the mushroom Pholiota aurivella by investigating its antimicrobial, antibiofilm, and antioxidant activities. The potential effects of the ethanol extract of the mushroom on a total of 27 different microorganisms, including strains with multidrug resistance (MDR), were examined. Add...
This study aimed to assess the antimicrobial activity of Daucus carota ssp. sativus var. atrorubens Alef. plant through disk diffusion and MIC (Minimum Inhibitory Concentration) methods, evaluate its antioxidant activity via the DPPH (2,2-diphenyl-1-picrylhydrazyl) method, and analyze its biochemical composition using GC-MS (Gas Chromatography-Mass...
Biofilm is a complex structure formed by microorganisms adhering to surfaces. It provides protection, contributes to the chronicity of infections, and enhances microbial resistance to treatment. Biofilms enhance microbial resistance to antibiotics and immune responses, complicating infection treatment. In this study, the biofilm formation capacitie...
Living organisms produce reactive oxygen species (ROS) during the oxygen processing. ROS damage biomolecules and causes oxidative stress. Antioxidants prevent cellular damage against these harmful effects of ROS by neutralizing free radicals. Medicinal plants provide a rich source of antioxidants to reduce oxidative stress and play an important rol...
The current study investigates the biochemical composition and biological activities of ethanol extract from the fruit body of Tricholoma bufonium, marking the first detailed examination of this species. The primary goal was to assess the antimicrobial, anti-biofilm, and antioxidant properties of ethanol extract from the fruit body of T. bufonium a...
Dünya genelinde artan antibiyotik kullanımı, antibiyotiklere dirençli mikroorganizmaların hızla yayılmasına neden olmaktadır. Bu durum, yeni ve etkili antimikrobiyal ajanların keşfini kritik bir öncelik haline getirmiştir. Mantarlar, ürettikleri çeşitli enzimler ve metabolitler sayesinde birçok patojene karşı güçlü antimikrobiyal aktivite göstermel...
Ginger (Zingiber officinale), originally from Asia, is now cultivated worldwide. For over 2500 years, it has been used in ethnobotany for its therapeutic benefits, including pain relief, diarrhea prevention, and aiding digestion. Antimicrobial tests have demonstrated that ginger exhibits both antibacterial and antifungal effects, leading to the dev...
Since ancient times, humans have been utilizing various plants for medicinal purposes, a practice that has persisted from early civilizations to the present day. Plants serve as rich sources of biomolecules, although many of their contents remain unidentified. Bryophytes are considered important reservoirs for new natural products, with mosses bein...
Juniper is a term used to identify shrub and tree species that fall under the genus Juniperus of the Cupressaceae family. The boiled and molasses forms of juniper berries have been traditionally utilized in folk medicine for centuries. In Turkey, juniper berries have been known to aid in treating shortness of breath, cough, abdominal pain, wound he...
Tissue scaffolds provide a structural environment for cells to adhere and proliferate. Thermoplastic polyurethanes (TPUs) are linear polymers that have high biocompatibility, biodegradability and superior viscoelastic behaviour. They are used in medical applications such as wound dressings. 3D printing is an innovative tool for tissue engineering....
antimikrobiyal aktivite
Mikroorganizmalar yaygın kanının aksine soliter değil kümeler halinde yaşamaya yatkındırlar. Bakteri popülasyonları da kendileri ürettikleri polimerik madde içerisinde yaşarlar. Bu polimer yapı biyofilm olarak adlandırılmaktadır. Oluşturdukları biyofilm bakteri popülasyonunu; antimikrobiyal ajanlardan, çevresel faktörlerden korumaktadır ve serbest...
Yaşamın birçok alanda kullanılan biyokimyasal bileşikler organizmaların hücrelerini ve diğer yapılarını oluşturmaktadır ve yaşam süreçlerini yürütmektedir. Proteinler, aminler, poliaminler, kompleks karbonhidratlar, organik asitler, lipitler, fenoller, flavonoidler, terpenoidler, aromatik bileşikler, hormonlar ve vitaminler gibi biyokimyasal bileşi...
İnsanlık tarihinin başlangıcından bu günlere dek bitkiler, gıda, ilaç, inşaat, tekstil ve enerji gibi çeşitli sektörlerde kullanılmış ve kullanılmaya devam etmektedir. Özellikle ilaç sektöründe, bitkiler en az diğer sektörlerde oldukları kadar önemli olup ilaç arayışlarında ilk başvurulan kaynaklardan olmuşlardır. Bu kaynak bitki gruplarından biris...
Origanum onites (Lamiaceae) is an Eastern Mediterranean plant that is widely used in Turkish traditional medicine. This study aimed to investigate the biochemical composition, antimicrobial activity, and antioxidant potential of O. onites. In this study, the biochemical composition of the O. onites ethanol extract (OOEt) was analyzed using GC-MS. T...
In this study, the chemical composition and biological activity of Allium scorodoprasum subsp. jajlae (Vved.) Stearn were investigated for the first time, focusing on its antimicrobial, antioxidant, and antibiofilm properties. A GC-MS analysis was employed to evaluate the composition of its secondary metabolites, identifying linoleic acid, palmitic...
In this study, the biochemical, antioxidant properties, and antimicrobial activity of the epiphytic leafy liverwort Frullania dilatata (L.) Dumort were investigated. Due to the scarcity and difficulty in obtaining liverworts, research on their bioactivity is limited; thus, this study aimed to uncover the potential of F. dilatata. The antimicrobial...
In this study, we investigated the antimicrobial, antioxidant, and antibiofilm activities and the biochemical composition of Achillea fraasii. The antimicrobial activity of A. fraasii ethanol extract (AFEt) was tested against 48 strains, and this is the first study testing the antimicrobial activity of this plant to this extent. The antioxidant act...
Cytinus hypocistis (L.) L. (Cytinaceae) is a Mediterranean parasitic plant used traditionally. This study aimed to investigate the in vitro antimicrobial, antioxidant activity, and biochemical composition of C. hypocistis ethanol extract (CHEt). The biochemical composition of CHEt was analyzed by GC-MS. The antimicrobial activity was investigated u...
Atropa belladonna is a perennial herbaceous plant in the Solanaceae family. The flowers of the plant are greenish purple in color and tube-shaped, the leaves are oval, and the fruits are black in color, shiny, and in a grape-like form. The A. belladonna plant, which appears mostly as a semi-shrub with fleshy roots, can reach a length of 100 cm to 1...
Like many animals, human beings have been using plants to combat diseases and infections since they first appeared on the scene of history. On the other hand, thousands of antibiotics have been synthesized and used since Alexander Flameng's discovery of penicillin in 1928. Antibiotics, which are an effective weapon in this war against bacteria, are...
Plants have been used in many areas from health to industry throughout human history and continue to be used today.
Daucus carota ssp. sativus var. atrorubens Alef. which is rich in vitamins and minerals and is also known colloquially as
the black carrot. It originated in Türkiye, the Middle, and the Far East and has been cultivated for about 300...
Fungi in the fungal kingdom constitute the second largest living group in the biosphere after insects. The genus Lyophyllum is in the class Agaricomycetes of the phylum Basidiomycetes and is widely distributed among northern temperate ecosystems. Although about 40 species have been defined in the genus Lyophyllum, it is the most studied Lyophyllum...
Antimicrobial resistance reduces the effectiveness of antibiotics and endangers human health by increasing the risk of death from serious diseases. We need to prevent both the transmission of resistant bacteria and the infections they cause, which are a growing threat with the increasing world population. In this context, new antimicrobial agents a...
Hibiscus syriacus is an ornamental plant, and it also has uses in traditional medicine. This study aimed to investigate in vitro antimicrobial activity and the biochemical composition of Hibiscus syriacus. In this study, the biochemical composition of ethanol extracts of H. syriacus flowers (HSFEt) and H. syriacus leaves (HSLEt) was analyzed by GC-...
The relationship between plants and humans is as old as human history. The branch of science that studies this relationship between humans and plants is called ethnobotany. People have been used plants in various ways, including food, medicine, clothing, goods, and firewood. Geophyte is a name given to herbaceous plants with special subsoil stems,...
In this study, the antimicrobial activity of Asparagus acutifolius, called "Tilkişen" and used in the treatment of diseases, was investigated in and around Aydın. The ethanol extracts obtained from fresh shoot tips and stems of A. acutifolius were tested against 45 bacteria and 3 fungi strains by the disk diffusion method. As a result of the study,...
This study aims to observe the antimicrobial and antioxidant activities of ethanol extract from the fruits of Pyracantha coccinea. Antimicrobial activity was tested against 45 bacteria and 3 yeasts by disk diffusion method and antioxidant activity was tested by the DPPH method. The results of this study showed that ethanol extract of fruits exhibit...
The Araceae family is one of the large families of Angiosperms. The family contains 105 genera and 3300 species. About 90% of the genera and about 95% of the species are found in tropical areas. It contains species of medical value and used as food among the public. Arum, Biarum, Dracunculus, Eminium, and Arisarum are the most important genera in T...
