Diego Rosselli

• MD, EdM, MSc, Neurologist
• Associate professor of Health Economics at Pontifical Xavierian University

Introducción: la enfermedad de Parkinson (EP) es un trastorno neurodegenerativo con impacto social y económico. Este estudio estimó su prevalencia y comorbilidades en Colombia a partir de datos del sistema de información del Ministerio de Salud, lo que permite una mejor comprensión de su distribución y carga en la población. Materiales y métodos: s...

Objective With an increasing prevalence, Alzheimer's Disease (AD) is the most common cause of dementia. However, a percentage of potentially modifiable cases have been reported. This article describes the prevalence of four of these potentially modifiable risk factors: hearing loss, diabetes mellitus (DM), obesity, and hypertension. Methods Descri...

Introducción: la colecistitis aguda es una de las complicaciones más frecuentes de la colelitiasis. En Colombia no existen estudios sobre su prevalencia, ni sobre las características sociodemográficas de la población afectada. Objetivos: establecer la prevalencia de la colecistitis aguda en Colombia y describir las características sociodemográficas...

Objectives: With an increasing prevalence, Alzheimer’s Disease (AD) is the most common cause of dementia. However, a percentage of potentially modifiable cases have been reported. This article describes the prevalence of 4 of its potentially modifiable risk factors (hearing loss, diabetes mellitus (DM), obesity, and hypertension). Methods: Descript...

Introducción: Colombia está entre los países líderes en cardiología y medicina cardiovascular en Latinoamérica. La transición demográfica actual ha generado mayor demanda de procedimientos de cirugía cardiovascular; sin embargo, con la situación de pandemia por la COVID-19, esta se vio afectada. Objetivo: describir las características demográficas...

Aunque la región va unos años atrás de países desarrollados como Italia, Francia o Japón, América Latina ha ido ganando un impulso inusitado en el proceso que llamamos transición demográfica, cuya principal característica es el rápido envejecimiento de la población. Una de las maneras más empleadas para ver la magnitud de ese cambio son las pirámid...

La capacidad de escuchar los sonidos surgió temprano en la evolución biológica como una herramienta de supervivencia que permitía detectar peligros inminentes, como la presencia de un predador acechante o de un objeto que se desploma. También ayudó a esos primeros carnívoros a detectar posibles presas, y sirvió sin duda en la comunicación entre mie...

A mediados del siglo XIX los salubristas británicos vieron la dificultad de hacer comparaciones entre la mortalidad de las diferentes regiones de Inglaterra y Gales. Algunos lugares, como el sur de la isla, concentraban a muchos pensionados que buscaban un clima más agradable para su retiro. Su población envejecida tenía, por razones obvias, una el...

Introducción. La apendicitis aguda es una afección común, con un pico de incidencia entre los 10 y 20 años. La cirugía es el tratamiento preferido y la apendicectomía por laparotomía sigue siendo el estándar, aunque el abordaje laparoscópico ha mostrado menos complicaciones. El objetivo de este artículo fue caracterizar tanto la enfermedad como el...

Background A randomized clinical trial (HiFlo-COVID-19 Trial) showed that among patients with severe COVID-19, treatment with high-flow oxygen therapy (HFOT) significantly reduced the need for invasive mechanical ventilation support and time for clinical recovery compared with conventional oxygen therapy (COT). However, the cost of this strategy is...

Background: Within the spectrum of health-related concerns, sexual and reproductive health stands out as a domain where gender-based disparities against women are notably pronounced. The introduction of male surgical sterilization procedures has the potential to mitigate this gender inequity. Methods: The Colombian Ministry of Health manages the SI...

El desarrollo de la inteligencia artificial (IA), así como la mejora evidente que han tenido las tecnologías digitales en el campo de la salud, obliga a plantearnos dos preguntas importantes que surgen al incorporar la IA como instrumento para una mejora en la calidad de atención. 1) ¿Podrá la IA reemplazar a los médicos? y 2) ¿Cuáles son las consi...

Since the introduction of Universal Varicella Vaccination (UVV) in the Argentinean National Immunization Program in 2015, a significant decline in the incidence of varicella has been reported. This study aimed to estimate the economic impact of single-dose UVV in Argentina from 2015 to 2019. The economic impact was assessed based on the observed in...

Introduction: Treatment of stroke is time-dependent and it challenges patients' social and demographic context for timely consultation and effective access to reperfusion therapies. Objective: The objective of this study was to relate indicators of social position to cardiovascular risk factors, time of arrival, access to reperfusion therapy, an...

Background In Colombia, the best strategy to establish indication for adjuvant chemotherapy in early breast cancer (EBC) remains unknown. This study aimed to identify the cost-utility of Oncotype DX™ (ODX) or Mammaprint™ (MMP) tests to establish the necessity of adjuvant chemotherapy. Methods This study used an adapted decision-analytic model to c...

Objective To describe the adherence to the use of positive air pressure (PAP) devices in a cohort of patients with sleep apnea syndrome in Colombia. Material and Methods Descriptive cross-sectional study of adult patients treated between January 2018 and December 2019 in the sleep clinic of a private insurer in Colombia. Results The analysis includ...

Background: Neuromyelitis optica spectrum disorder (NMOSD) is a rare entity with severe inflammatory demyelinating events of the central nervous system with debilitating sequelae. Its global prevalence ranges between 0.5 and 4/100,000 individuals, with variations by region and ethnicity. Latin America lacks epidemiological data on the disease, and...

Objetivo: evaluar la costoefectividad de la terapia con trióxido de arsénico más treintona (ATO más ATRA) vs. manejo estándar ATRA+idarubicina (IDA) para el tratamiento de primera línea de leucemia promielocitica aguda (LPA) desde la perspectivadel sistema de salud colombiano. Materiales y métodos: para estimar la costoefectividad se diseñó un mode...

Introducción: los estimados de prevalencia de apnea de sueño se basan en encuestas que exploran factores como ronquido o somniolencia diurna. El Ministerio de Salud de Colombia posee un sistema de infomación que ha sido empleado para estimar la prevalencia de numerosas enfermedades.Objetivo: analizar la información de pacientes con diagnóstico de a...

Background: An institutional management protocol for patients with subarachnoid hemorrhage (SAH) based on initial cardiac assessment, permissiveness of negative fluid balances, and use of a continuous albumin infusion as the main fluid therapy for the first 5 days of the intensive care unit (ICU) stay was implemented at our hospital in 2014. It ai...

Introduction Latin America comprises a large set of culturally diverse middle-income countries sharing an inequality gap and a rapidly aging population. A better informed growing middle class adds to the pressure on fragmented health systems that strive to attain universal coverage. Cost containment becomes crucial for sustainability. Areas covere...

Hemos leído con interés el artículo ‘Epidemiolo-gía de la miastenia grave en la península ibéri-ca y Latinoamérica’, recientemente publicado en su revista [1]. Como punto inicial, queremos felicitar a los autores por su esfuerzo en la reco-lección de los estudios de cada país. La variabili-dad que ellos encuentran en tasas de incidencia y prevalenc...

Introducción. A lo largo de los años se ha observado una importante brecha de género en la especialidad de ortopedia y traumatología. Su persistencia en otros países sugiere una evolución similar en Colombia. Objetivo. Determinar la distribución por sexo de los residentes de ortopedia y traumatología en Colombia en tres momentos fundamentales: la i...

Objectives: to estimate the burden of disease related to chronic pain in Ecuador. Methods: We used Global Burden of Disease (GBD) methods to estimated disability-adjusted life years (DALYs) related to chronic pain in Ecuador. We focused on chronic pain related to lumbar pain, osteoarthritis, post-herpetic neuralgia, diabetic neuropathy, cancer-r...

Introduction Psoriasis is a chronic systemic inflammatory disease manifesting as erythematous and desquamative dermatoses. Objectives This study estimated the cost per responder (CPR) for the treatment of moderate-to-severe plaque psoriasis with biologic therapies approved by the Colombian regulatory agency. Methods This secondary study used a mo...

Background: The impact of immunosuppression in solid organ transplant recipients with SARS-CoV-2 infection is unknown. The knowledge about the behavior of different immunosuppression schemes in clinical outcomes is scarce. This study aimed to determine the risk of death in kidney transplant recipients with COVID-19 under two different schemes of i...

RESUMEN Colombia es reconocida en la región por la universalidad tanto de su sistema de salud como de sus sistemas de información. Si bien el Sistema de Información Integral para la Protección Social (SISPRO) tiene como finalidad cumplir una función administrativa dentro del sistema de salud, se están reconociendo sus usos en investigación. SISPRO...

Background: In Colombia, the best strategy to establish indication for adjuvant chemotherapy in early breast cancer (EBC) remains unknown. This study aimed to identify the cost-utility of Oncotype DX™ (ODX) or Mammaprint™ (MMP) tests to establish the necessity of adjuvant chemotherapy. Methods: This study used an adapted decision-analytic model to...

Introduction Psoriatic arthritis is an inflammatory arthritis with a wide range of manifestations. The complexity of the disease is a barrier to understanding it, however knowledge about the disease has increased considerably over time, due to advances in genetics, immunology, imaging, and a better understanding of epidemiology. The exact prevalenc...

Objetivo: Caracterizar el impacto de la pandemia de COVID-19 sobre la carga de trabajo de la radiología en Colombia. Materiales y métodos: Estudio retrospectivo, de las bases de datos del Ministerio de Salud, de los estudios radiológicos realizados entre 2015 y 2021. Se comparó el número de procedimientos durante el periodo previo a la pandemia con...

Objectives To evaluate the cost-effectiveness of the nonsurgical periodontal treatment (NSPT) compared with supragingival therapy in type II diabetics with periodontitis. Methods A decision tree analysis was used to estimate the costs and health outcomes of two periodontal therapies in a hypothetical cohort of type II diabetics with periodontitis....

Objetivo: establecer la estrategia más costo-útil para Colombia entre ofrecer el tratamiento de quimioterapia adyuvante (QT-A) a todas las pacientes (estrategia estándar) con cáncer de mama temprano, receptor hormonal (RH) positivo, Her 2 neu negativo, sin compromiso ganglionar (N0), con criterios clínicos de alto riesgo de recurrencia o definir la...

Objectives to assess the burden of disease of chronic pain in Colombia. Methods we estimated disability adjusted life years (DALYs) attributable to chronic pain using Global Burden of Disease (GBD) method. We identified diagnostic codes related to chronic pain considering lumbar pain, osteoarthritis, post-herpetic neuralgia, diabetic neuropathy, c...

Background: The impact of immunosuppression in solid organ transplant recipients with SARS CoV-2 infection is unknown. The knowledge about the behavior of different immunosuppression schemes in clinical outcomes is scarce. This study aimed to determine the risk of death in kidney transplant recipients with COVID-19 under two different schemes of im...

Para muchas personas, la Economía en general, incluso la Economía de la Salud, es percibida como la ciencia que se ocupa de estudiar el dinero. Esa es una interpretación errada. Como ciencia social, la Economía va mucho más allá, y en sus análisis, así como en sus recomendaciones, incorpora además de la asignación de los recursos (de los cuales el...

Introducción: La N-acetilcisteína (NAC) es uno de los medicamentos que se ha propuesto en el manejo de pacientes con covid-19. Este fármaco cuenta con más de cincuenta años de uso en profilaxis y terapia de varias condiciones clínicas. Objetivo: Revisar la literatura que recoja la evidencia disponible sobre el uso de NAC como adyuvante en inmunizac...

Objective To describe the relation between corruption indicators and statistics on noncommunicable diseases and their risk factors by continent. Methods An ecological study was conducted to examine the relation of the GINI coefficient, the Country Policy and Institutional Assessment (CPIA), and the Corruption Perception Index (CPI) with noncommuni...

Objectives Azathioprine has been the therapy of choice for the maintenance of remission in patients with antineutrophil cytoplasm antibody (ANCA)-associated systemic vasculitis, but recent studies show that rituximab could be more effective. To evaluate the cost-effectiveness of azathioprine, fixed-schedule rituximab, and tailored-dose rituximab fo...

Objectives Advanced melanoma accounts for 4% of malignant skin tumors, and approximately 80% of deaths are attributed to it. The most frequent mutation of the RAF gene is BRAFV600, which has been associated with a worse prognosis. The objective of the research was to evaluate the cost-effectiveness of the combined regimen of dabrafenib plus trameti...

Introducción. La causa más común de estenosis laringotraqueal benigna es iatrogénica, secundaria a intubación orotraqueal. El manejo quirúrgico sigue siendo la alternativa que ha mostrado mejores resultados a largo plazo. El objetivo de este estudio fue analizar la experiencia en el manejo quirúrgico de la estenosis laringotraqueal durante 15 años...

Objectives: (1) To estimate the prevalence, geographic distribution, and demographic characteristics of patients diagnosed with mental and behavioral disorders due to the use of opioids in Colombia, between 2009 and 2018. (2) To describe the opioid sales trends in Colombia over the last few years. Methods: We conducted an observational study ana...

Background and Objective Prostate cancer is a multifactorial disease and is among the top five causes of death in men worldwide. The Colombian Ministry of Health has adopted the Integrated Information System on Social Protection (Sistema Integrado de Información de la Protección Social, SISPRO, by its Spanish acronym) registry to collect comprehens...

Objective Using data from the Ministry of Health of Colombia, we performed an analysis of prevalence and general demographic characteristics of patients with inflammatory myopathies, with data from 2012 to 2018. Design A descriptive cross-sectional study based on data from the Ministry of Health of Colombia. We used as key terms the diagnostic cod...

Introduction Many authors have highlighted the management and outcomes of liver transplant patients with SARS -CoV2, however, there is a reduced experience identified with Hispanic or Latino patients [1]. We would like to share our experience with liver transplantation and SARS-CoV-2 infection (Real-time PCR identification) during 2020. Objectives...

Objectives: (1) To estimate the prevalence, geographic distribution, and demographic characteristics of patients diagnosed with mental and behavioral disorders due to the use of opioids in Colombia, between 2009 and 2018. (2) To describe the opioid sales trends in Colombia over the last few years. Methods: We conducted an observational study analyz...

For centuries, cannabis has been used with many different purposes, including medicinal use, usually bypassing any formal approval process. However, during the last decade, interest in cannabis in medicine has been increasing, and several countries, including the United States and Canada, have produced their own legislation about marihuana and cann...

Introduction Osteoporosis is considered a healthcare problem due to the increased risk of fractures and high cost of care. In Colombia, the Ministry of Health introduced SISPRO, a tool to collect nationwide information from the health system. The information collected from SISPRO is available for scientific analysis. This article presents an analys...

Corruption in healthcare is on the rise. When corruption infiltrates global health, causes embezzlement of public health funds, malfunctioning medical equipment, fraudulent or ineffective health services such as expired medicines and fake vaccines that could have life-or-death consequences. A corrupt healthcare system, amid global health crises lik...

Objectives We designed and conducted a narrative review consistent with the PRISMA guidelines (PROSPERO registration number: CRD42018099498) to evaluate the association between environmental metals (manganese, mercury, iron) and Parkinson’s Disease (PD) in low and middle-income countries (LMIC). Methods Data sources: A total of 19 databases were s...

Background The best strategy to establish indication for adjuvant chemotherapy in early breast cancer (EBC) in Colombia is unknown. This study aimed to identify the cost-effectiveness of various strategies to establish the necessity of adjuvant chemotherapy.Methods This study used an adapted decision-analytic model to compare cost and outcomes of c...

Background: In Colombia, the best strategy to establish indication for adjuvant chemotherapy in early breast cancer (EBC) remains unknown. This study aimed to identify the cost-effectiveness of various strategies to establish the necessity of adjuvant chemotherapy. Methods: This study used an adapted decision-analytic model to compare cost and outc...