Diego Ezequiel Egoburo

Universidad de Buenos Aires | UBA · Department of Biological Chemistry

Global regulators are hierarchical regulators that control directly or indirectly multiple genes simultaneously, optimizing the use of metabolic pathways according to growth conditions. Escherichia coli is a model facultative bacterium capable of adapting to many different environments, ranging from the intestinal tracts of suitable hosts to fresh...

Thermoanaerobacterium thermosaccharolyticum GSU5 was isolated from animal dung collected in a pasture plain in Buenos Aires, Argentina. This thermophilic and anaerobic microorganism was able to produce butanol and ethanol, but not acetone, using sugars such as xylose, arabinose, glucose, galactose, fructose, sucrose, and cellobiose. Key metabolic e...

The environmental strain Aeromonas salmonicida subsp. pectinolytica 34melT produces abundant melanin through the homogentisate pathway in several culture media, but unexpectedly not when grown in a medium containing glycerol. Using this observation as a starting point, this study investigated the underlying causes of the inhibition of melanin synth...

Environments co-contaminated with heavy metals and hydrocarbons have become an important problem worldwide, especially due to the effect of metals on hydrocarbon degrading microorganisms. Pseudomonas extremaustralis, a bacterium isolated from a pristine pond in Antarctica, showed high capabilities to cope with environmental stress and a very versat...

Manipulation of global regulators is one of the strategies used for the construction of bacterial strains suitable for the synthesis of bioproducts. However, the pleiotropic effects of these regulators can vary under different conditions and are often strain dependent. This study analyzed the effects of ArcA, CreC, Cra, and Rob using single deletio...

The microbial production of biofuels and other added-value chemicals is often limited by the intrinsic toxicity of these compounds. The phasin PhaP from the soil bacterium Azotobacter sp. strain FA8 is a polyhydroxyalkanoate granuleassociated protein that protects recombinant Escherichia coli against several kinds of stress. PhaP enhances growth an...

1,3-Propanediol (1,3-PDO) is an important chemical widely used in polymer production. This compound has been traditionally obtained by chemical synthesis, but it can also be obtained from bacterial fermentation using glycerol as renewable carbon source. Since 1,3-PDO and glycerol have a similar chromatographic behavior, it is not easy to determine...